Cited by 398Gestational Diabetes Research and ManagementDiabetes Management and ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: paving the way for new diagnostic criteria for gestational diabetes mellitus

Open access

Coustan, Donald R., Lowe, Lynn P., Metzger, Boyd E., Dyer, Alan R.·2010·American Journal of Obstetrics and Gynecology

DOI 10.1016/j.ajog.2010.04.006PMC PMC2897007

Open this paper in CoChat — free account

Abstract

The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study was performed in response to the need for internationally agreed upon diagnostic criteria for gestational diabetes, based upon their predictive value for adverse pregnancy outcome. Increases in each of the 3 values on the 75-g, 2-hour oral glucose tolerance test are associated with graded increases in the likelihood of pregnancy outcomes such as large for gestational age, cesarean section, fetal insulin levels, and neonatal fat content. Based upon an iterative process of decision making, a task force of the International Association of Diabetes and Pregnancy Study Groups recommends that the diagnosis of gestational diabetes be made when any of the following 3 75-g, 2-hour oral glucose tolerance test thresholds are met or exceeded: fasting 92 mg/dL, 1-hour 180 mg/dL, or 2 hours 153 mg/dL. Various authoritative bodies around the world are expected to deliberate the adoption of these criteria.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.ajog.2010.04.006

Cites

17 of 17 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Diagnosis and Classification of Diabetes Mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc11-s062 · Cited by 14,094
Hyperglycemia and adverse pregnancy outcomes
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0707943 · Cited by 5,563
Diagnosis and classification of diabetes mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc10-s062 · Cited by 5,491
International Association of Diabetes and Pregnancy Study Groups Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy
International Association of Diabetes and Pregnancy Study Groups Consensus Panel (2010) · Diabetes Care · doi:10.2337/dc09-1848 · Cited by 5,390
Effect of Treatment of Gestational Diabetes Mellitus on Pregnancy Outcomes
Crowther, C. A., Hiller, J. E., Moss, J. R., McPhee, A. J., Jeffries, W. S., & Robinson, J. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa042973 · Cited by 3,159
A Multicenter, Randomized Trial of Treatment for Mild Gestational Diabetes
Landon, M. B., Spong, C. Y., Thom, E., Carpenter, M. W., Ramin, S. M., Casey, B., Wapner, R. J., Varner, M. W., Rouse, D. J., Thorp, J. M., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0902430 · Cited by 2,122
National Health and Nutrition Examination Survey
Rothwell, C. J. (2009) · Springer eBooks · doi:10.1007/978-0-387-78665-0_6177 · Cited by 2,093
Summary and recommendations of the Fifth International Workshop-Conference on gestational diabetes mellitus
Metzger, B. E., Buchanan, T. A., Coustan, D. R., de Leiva, A., Dunger, D. B., Hadden, D. R., Hod, M., Kitzmiller, J. L., Kjos, S. L., Oats, J. N., et al. (2007) · Diabetes Care · doi:10.2337/dc07-s225 · Cited by 1,908
Self-citation
Untitled work
(1964) · PubMed · Cited by 1,230
Untitled work
(1998) · PubMed · Cited by 992
Self-citation

Show all 16 references

Sorted by citations

Items 101–200 of 398

The impact of pre-pregnancy body mass index on the risk of gestational diabetes
Singh, J., Huang, C.-C., Driggers, R. W., Timofeev, J., Amini, D., Landy, H. J., Miodovnik, M., & Umans, J. G. (2011) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2012.626920 · Cited by 35
Is the evidence strong enough to change the diagnostic criteria for gestational diabetes now?
Visser, G. H. A., & de Valk, H. W. (2012) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2012.10.881 · Cited by 35
Exercise for pregnant women with gestational diabetes for improving maternal and fetal outcomes
Ceysens, G., Brown, J., & Boulvain, M. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012202 · Cited by 35
Feasibility and effectiveness of a lifestyle intervention after complicated pregnancies to improve risk factors for future cardiometabolic disease
Berks, D., Hoedjes, M., Raat, H., Franx, A., Looman, C. W. N., van Oostwaard, M. F., Papatsonis, D. N. M., Duvekot, J. J., & Steegers, E. A. P. (2018) · Pregnancy Hypertension · doi:10.1016/j.preghy.2018.12.004 · Cited by 35
The prevalence of gestational diabetes mellitus among Aboriginal and Torres Strait Islander women in Australia: a systematic review and meta‐analysis
Chamberlain, C., Joshy, G., Li, H., Oats, J. J. N., Eades, S., & Banks, E. (2014) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2570 · Cited by 33
Analysis of correlations between the placental expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 and selected maternal and fetal parameters in pregnancies complicated by diabetes mellitus
Stanirowski, P. J., Szukiewicz, D., Pyźlak, M., Abdalla, N., Sawicki, W., & Cendrowski, K. (2017) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2017.1387897 · Cited by 33
“Outcome study [14], (ii) patients with the PGDM type”
Background
Early markers of gestational diabetes mellitus
Omazić, J., Ivić, V., Wagner, J., Müller, A., Zibar, L., Kadivnik, M., & Viljetić, B. (2021) · Biochemia Medica · doi:10.11613/bm.2021.030502 · Cited by 37
“(15-17).”
Attitudes of women with gestational diabetes toward diet and exercise: a qualitative study
Smyth, S., Mulligan, K., Rutter, E., Harrington, L., Hatunic, M., & Higgins, M. (2023) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2022.2155045 · Cited by 34
Prevalence of type 2 diabetes mellitus in women of childbearing age in Africa during 2000–2016: a systematic review and meta-analysis
Chivese, T., Werfalli, M., Magodoro, I. M., Chinhoyi, R. L., Kengne, A. P., Norris, S. A., & Levitt, N. S. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-024345 · Cited by 31
Antepartum A1C, maternal diabetes outcomes, and selected offspring outcomes: an epidemiological review
Katon, J. G., Williams, M. A., Reiber, G. E., & Miller, E. (2011) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2011.01195.x · Cited by 31
Screening for hyperglycaemia in pregnancy: Consensus and controversy
Waugh, N. R., Pearson, D. W. M., & Royle, P. (2010) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.06.004 · Cited by 30
Antenatal inflammation and gestational diabetes mellitus risk among pregnant African-American women
Bossick, A. S., Peters, R. M., Burmeister, C., Kakumanu, N., Shill, J., & Cassidy‐Bushrow, A. E. (2016) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2016.03.005 · Cited by 31
Epigenetic Links between Microbiota and Gestational Diabetes
Mora-Janiszewska, O., Faryniak-Zuzak, A., & Darmochwał-Kolarz, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031831 · Cited by 28
Comments on gestational diabetes mellitus: from pathophysiology to clinical practice
Poulakos, P., Mintziori, G., Tsirou, E., Taousani, E., Savvaki, D., Harizopoulou, V. C., & Goulis, D. G. (2015) · HORMONES · doi:10.14310/horm.2002.1570 · Cited by 33
Maternal insulin resistance, triglycerides and cord blood insulin in relation to post‐natal weight trajectories and body composition in the offspring up to 2 years
Brunner, S., Schmid, D., Hüttinger, K., Much, D., Heimberg, E., Sedlmeier, E. ‐., Brüderl, M., Kratzsch, J., Bader, B., Amann‐Gassner, U., et al. (2013) · Diabetic Medicine · doi:10.1111/dme.12298 · Cited by 29
Objective assessment of heparin requirements for hemodialysis in humans.
Ireland, H., Lane, D. A., & Curtis, J. R. (1984) · PubMed · Cited by 29
Thiol/disulfide homeostasis in predicting adverse perinatal outcomes at 24–28 weeks of pregnancy in gestational diabetes
Özler, S., Öztaş, E., Çağlar, A. T., Uygur, D., Ergin, M., Erel, Ö., & Danışman, N. (2016) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2016.1141885 · Cited by 27
“According to the results of the hyperglycemia and adverse pregnancy outcome (HAPO) study, diagnostic criteria for gestational diabetes were suggested to be revised with decreased thresholds considering their predictive value for adverse pregnancy outcomes [20].”
Result
A two-step screening algorithm including fasting plasma glucose measurement and a risk estimation model is an accurate strategy for detecting gestational diabetes mellitus
Göbl, C. S., Bozkurt, L., Rivic, P., Schernthaner, G.-H., Weitgasser, R., Pacini, G., Mittlböck, M., Bancher‐Todesca, D., Lechleitner, M., & Kautzky‐Willer, A. (2012) · Diabetologia · doi:10.1007/s00125-012-2726-7 · Cited by 27
“The IADPSG Consensus Panel recently revised its recommendations for the diagnosis of GDM, particularly based on the results of the HAPO (Hyperglycemia and Adverse Pregnancy Outcome) study, aiming to close the ‘lack of international uniformity in the approach to ascertainment and diagnosis of GDM’ [20, 25].”
BackgroundMethod
Three-dimensional ultrasonographic placental volume in gestational diabetes mellitus
Pala, H. G., Ülkümen, B. A., Koyuncu, F. M., & BAYTUR, Y. B. (2015) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2015.1012066 · Cited by 28
Vitamin D and gestational diabetes
Joergensen, J. S., Lamont, R., & Torloni, M. R. (2014) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000064 · Cited by 29
Maternal hyperglycemia according to IADPSG criteria as a predictor of perinatal complications in women with gestational diabetes: a retrospective observational study
Zawiejska, A., Wender-Ożegowska, E., Radzicka, S., & Brązert, J. (2013) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2013.863866 · Cited by 27
Impact des nouveaux critères de dépistage sur la prévalence du diabète gestationnel
Wery, E., Vambergue, A., Gouëff, F. L., Vincent, D., & Deruelle, P. (2013) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2013.01.005 · Cited by 28
In-Hospital Breastfeeding Experiences Among Women with Gestational Diabetes
Oza‐Frank, R. B., & Gunderson, E. P. (2017) · Breastfeeding Medicine · doi:10.1089/bfm.2016.0197 · Cited by 27
Screening and Management of Gestational Diabetes in Mexico: Results from a Survey of Multilocation, Multi-Health Care Institution Practitioners
Dainelli, L., Prieto Patron, A., Silva-Zolezzi, I., Sosa Rubi, S. G., Espino y Sosa, S., Reyes Muñoz, E., Lopez-Ridaura, R., & Detzel, P. (2018) · Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy · doi:10.2147/dmso.s160658 · Cited by 26
Increased expression of immune-related genes in leukocytes of patients with diagnosed gestational diabetes mellitus (GDM)
Wójcik, M., Zieleniak, A., Żurawska-Kliś, M., Cypryk, K., & Woźniak, L. A. (2015) · Experimental Biology and Medicine · doi:10.1177/1535370215615699 · Cited by 26
Maternal Sleep-Disordered Breathing in Pregnancy and Increased Nocturnal Glucose Levels in Women with Gestational Diabetes Mellitus
Newbold, R., Benedetti, A., Kimoff, R. J., Meltzer, S., Garfield, N., Dasgupta, K., Gagnon, R., Lavigne, L., Olha, A., Rey, E., et al. (2021) · Chest · doi:10.1016/j.chest.2020.07.014 · Cited by 28
Prevalence of gestational diabetes mellitus among Indigenous women and comparison with non-Indigenous Australian women: 1990-2009
Chamberlain, C., Banks, E., Joshy, G., Diouf, I., Oats, J. J. N., Gubhaju, L., & Eades, S. (2014) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12213 · Cited by 26
50-Gram glucose challenge test: is it indicative of outcomes in women without gestational diabetes mellitus?
Yee, L. M., Cheng, Y. W., Liddell, J., Block-Kurbisch, I. J., & Caughey, A. B. (2011) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2010.546450 · Cited by 24
Association between gestational diabetes mellitus diagnostic criteria and adverse pregnancy outcomes—a systematic review and meta-analysis of adjusted effect sizes from studies using current diagnostic criteria
Mahmoud, E., Elsayed, A. M., Elsayed, B. M. S., Elsalakawi, Y., Gopinath, A., & Chivese, T. (2024) · BMJ Open · doi:10.1136/bmjopen-2024-091258 · Cited by 29
Placental Histomorphometry in Gestational Diabetes Mellitus
Bentley–Lewis, R., Dawson, D. L., Wenger, J., Thadhani, R., & Roberts, D. J. (2014) · American Journal of Clinical Pathology · doi:10.1309/ajcpx81aunfpotll · Cited by 23
Breastfeeding Self-efficacy of Women With and Without Gestational Diabetes
Chertok, I. R. A., & Sherby, E. (2016) · MCN The American Journal of Maternal/Child Nursing · doi:10.1097/nmc.0000000000000233 · Cited by 23
The experience of gestational diabetes for indigenous Māori women living in rural New Zealand: qualitative research informing the development of decolonising interventions
Reid, J., Anderson, A., Cormack, D. M., Reid, P., & Harwood, M. L. N. (2018) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-018-2103-8 · Cited by 27
“The short-term effects of GDM are well documented [4] and our understanding about the long term consequences for mother and child is growing as results from longitudinal studies become available [5, 6].”
Background
Effectiveness of Low Glycemic Index Diet Consultations Through a Diet Glycemic Assessment App Tool on Maternal and Neonatal Insulin Resistance: A Randomized Controlled Trial
Zhang, Y., Wang, L., Yang, W., Niu, D., Li, C., Wang, L., Gu, P., Xia, Y., Shen, Y., Yan, J., et al. (2019) · JMIR mhealth and uhealth · doi:10.2196/12081 · Cited by 23
A Review on Research Progress in the Application of Glycosylated Hemoglobin and Glycated Albumin in the Screening and Monitoring of Gestational Diabetes
Liu, X., Wu, N., & Al-Mureish, A. (2021) · International Journal of General Medicine · doi:10.2147/ijgm.s296316 · Cited by 26
Morbidity Associated with Fetal Macrosomia among Women with Diabetes Mellitus
Dudley, A. O., Figueroa, H. M., Ellis, V., Chen, H.-Y., Chauhan, S. P., & Jenner, Z. B. (2017) · American Journal of Perinatology · doi:10.1055/s-0037-1608811 · Cited by 23
Pregnancy phthalate metabolite concentrations and infant birth weight by gradations of maternal glucose tolerance
Noor, N., Ferguson, K. K., Meeker, J. D., Seely, E. W., Hauser, R. B., James-Todd, T. M., & McElrath, T. F. (2019) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2018.12.005 · Cited by 23
Association of Shorter Height with Increased Risk of Ischaemic Placental Disease
Ogawa, K., Morisaki, N., Saito, S., Sato, S., Fujiwara, T., & Sago, H. (2017) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12351 · Cited by 22
DESFECHOS MATERNO-FETAIS DE GESTANTES COM E SEM DIABETES MELLITUS GESTACIONAL
Silva, R. R. E., de Souza, M. L. R., de Oliveira, L. C., Silva, T. R. E., Bertoli, J. P. D. P., & Silva, J. C. (2019) · Arquivos Catarinenses de Medicina · doi:10.63845/370yzg60 · Cited by 21
Pre-Pregnancy Adherence to Mediterranean Diet and Risk of Gestational Diabetes Mellitus: A Prospective Cohort Study in Greece
Tranidou, A., Dagklis, T., Magriplis, E., Apostolopoulou, A., Tsakiridis, I., Chroni, V., Tsekitsidi, E., Kalaitzopoulou, I., Pazaras, N., & Chourdakis, M. (2023) · Nutrients · doi:10.3390/nu15040848 · Cited by 21
“For the diagnosis of GDM, all women underwent a 75 g oral glucose tolerance test (OGTT) at 24–28 weeks of gestation, following the criteria suggested by the Hellenic Society of Obstetricians and Gynecologists (HSOG) [36], which are based on the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study [37].”
Method
Prediction of Gestational Diabetes Mellitus in the First Trimester of Pregnancy Based on Maternal Variables and Pregnancy Biomarkers
Tranidou, A., Tsakiridis, I. G., Apostolopoulou, A., Xenidis, T., Pazaras, N., Mamopoulos, A. M., Athanasiadis, A. P., Chourdakis, M., & Dagklis, T. (2023) · Nutrients · doi:10.3390/nu16010120 · Cited by 23
“With regards to GDM screening, the Hellenic Society of Obstetricians and Gynecolo-gists recommends universal screening at 24–28 weeks of gestation, using GDM diagnostic criteria that are based on the results of the “Hyperglycemia and Adverse Pregnancy Out-come” (HAPO) study [22].”
Method
COVID-19 pandemic gestational diabetes screening guidelines: A retrospective study in Australian women
Zhu, S., Meehan, T., Veerasingham, M., & Sivanesan, K. (2021) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2021.01.021 · Cited by 20
Le diabète gestationnel
Sénat, M., & Deruelle, P. (2016) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2016.01.009 · Cited by 28
Investigation on the suitability of the International Association of Diabetes and Pregnancy Study Group diagnostic criteria for gestational diabetes mellitus in China
Shang, M., Lin, L., Ma, L., & Yin, L. (2014) · Journal of Obstetrics and Gynaecology · doi:10.3109/01443615.2013.832177 · Cited by 19
“…recommended new GDM diagnostic criteria mainly based on the results from the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study (Metzger et al. 1991; HAPO Study Cooperative Research Group 2002; Coustan et al. 2010; International Association of Diabetes and Pregnancy Study Groups 2010).”
Method
Maternal overweight and obesity and its association with metabolic changes and fetal overgrowth in the absence of gestational diabetes mellitus: A prospective cohort study
Monod, C., Kotzaeridi, G., Linder, T., Yerlikaya‐Schatten, G., Wegener, S., Mosimann, B., Henrich, W., Tura, A., & Göbl, C. S. (2023) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.14688 · Cited by 21
Prenatal Hyperglycemia Exposure and Cellular Stress, a Sugar-Coated View of Early Programming of Metabolic Diseases
Tozour, J. N., Hughes, F., Carrier, A., Vieau, D., & Delahaye, F. (2020) · Biomolecules · doi:10.3390/biom10101359 · Cited by 19
A mouse model of gestation-specific transient hyperglycemia for translational studies
Li, H. Y., Liu, Y. X., Harvey, L., Shafaeizadeh, S., van der Beek, E. M., & Han, W. (2020) · Journal of Endocrinology · doi:10.1530/joe-19-0516 · Cited by 20
Early-Pregnancy Intermediate Hyperglycemia and Adverse Pregnancy Outcomes Among Women Without Gestational Diabetes
Ye, Y., Xiong, Y., Zhou, Q., Xiao, X., & Li, X. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab841 · Cited by 18
Impact of Gestational Diabetes Detection Thresholds on Infant Growth and Body Composition: A Prospective Cohort Study Within a Randomized Trial
Manerkar, K., Crowther, C. A., Harding, J. E., Meyer, M. P., Conlon, C. A., Rush, E. C., Alsweiler, J. M., McCowan, L. M. E., Rowan, J. A., Edlin, R., et al. (2024) · Diabetes Care · doi:10.2337/dc23-0464 · Cited by 19
Gestational Diabetes Mellitus Screening Using the One-Step Versus Two-Step Method in a High-Risk Practice
Fuller, K., & Borgida, A. (2014) · Clinical Diabetes · doi:10.2337/diaclin.32.4.148 · Cited by 19
Gestational diabetes mellitus and risk of neurodevelopmental disorders in young offspring: does the risk differ by race and ethnicity?
Liu, X., Zhu, Y., Seamans, M. J., Nianogo, R. A., Janzen, C., Fei, Z., & Chen, L. (2023) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2023.101217 · Cited by 21
Diabetes in pregnancy: glycemia control guidelines and rationale
Karakash, S. D., & Einstein, F. H. (2011) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e3283446ed2 · Cited by 18
Combined intervention of swimming plus metformin ameliorates the insulin resistance and impaired lipid metabolism in murine gestational diabetes mellitus
Huang, L., Yue, P., Wu, X., Yu, T., Wang, Y., Zhou, J., Kong, D., & Chen, K. (2018) · PLoS ONE · doi:10.1371/journal.pone.0195609 · Cited by 18
Diet and exercise interventions for preventing gestational diabetes mellitus
Crane, M., Bain, E., Tieu, J., Han, S., Middleton, P., & Crowther, C. A. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010443 · Cited by 22
Early Screening and Diagnosis of Gestational Diabetes Mellitus (GDM) and Its Impact on Perinatal Outcomes
Bastian, B., Smithers, L. G., Pape, A., Davis, W., Fu, K., & Francois, M. (2024) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2024.111890 · Cited by 18
The simultaneous occurrence of gestational diabetes and hypertensive disorders of pregnancy affects fetal growth and neonatal morbidity
Onuoha, C., Schulte, C. C. M., Thaweethai, T., Hsu, S. C., Pant, D. B., James, K. E., Sen, S., Kaimal, A. J., & Powe, C. E. (2024) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2024.03.009 · Cited by 20
How safe is metformin when initiated in early pregnancy? A retrospective 5-year study of pregnant women with gestational diabetes mellitus from India
Vanlalhruaii, Dasgupta, R., Ramachandran, R., Mathews, J. E., Regi, A., Thomas, N., Gupta, V., Visalakshi, P., Asha, H. S., Paul, T. V., et al. (2018) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2018.01.002 · Cited by 17
Fasting plasma glucose, diagnosis of gestational diabetes and the risk of large for gestational age: a regression discontinuity analysis of routine data
Tennant, P. W. G., Doxford‐Hook, E., Flynn, L., Kershaw, K., Goddard, J. R., & Stacey, T. (2021) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16906 · Cited by 17
The effect of dietary counselling on food intakes in pregnant women at risk for gestational diabetes: a secondary analysis of a randomised controlled trial RADIEL
Valkama, A., Koivusalo, S. B., Lindström, J., Meinilä, J. M., Kautiainen, H., Stach‐Lempinen, B., Rönö, K., Klemetti, M. M., Pöyhönen‐Alho, M., Tiitinen, A. E., et al. (2015) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2015.205 · Cited by 18
Compliance with National Institute of Health and Care Excellence risk-based screening for Gestational Diabetes Mellitus in nulliparous women
Murphy, N. M., McCarthy, F. P., Khashan, A. S., Myers, J., Simpson, N., Kearney, P. M., Greene, R. A., Poston, L., & Kenny, L. C. (2016) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.01.044 · Cited by 17
Evaluation of SCUBE-1 levels as a placental dysfunction marker at gestational diabetes mellitus
Tekın, Y. B., Erin, K. B., & Yılmaz, A. (2019) · Gynecological Endocrinology · doi:10.1080/09513590.2019.1683537 · Cited by 17
Neonatal birth waist is positively predicted by second trimester maternal active ghrelin, a pro-appetite hormone, and negatively associated with third trimester maternal leptin, a pro-satiety hormone
Valsamakis, G., Papatheodorou, D. C., Naoum, A., Margeli, A., Papassotiriou, I., Kapantais, E., Creatsas, G. C., Kumar, S., & Mastorakos, G. P. (2014) · Early Human Development · doi:10.1016/j.earlhumdev.2014.07.001 · Cited by 17
Deciphering DNA Methylation in Gestational Diabetes Mellitus: Epigenetic Regulation and Potential Clinical Applications
Li, N., Liu, H., & Liu, S.-M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25179361 · Cited by 16
“Since 2010, the International Association of Diabetic Pregnancy Study Groups’ (IADPSG) recommended criteria (i.e., the oral glucose tolerance test) [16] have increasingly been used as diagnostic criteria for GDM globally; however, there is still ongoing debate about their usage.”
Background
Characteristics of different risk factors and fasting plasma glucose for identifying GDM when using IADPSG criteria: a cross-sectional study
Saeedi, M., Hanson, U., Simmons, D. S., & Fadl, H. (2018) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-018-1875-1 · Cited by 18
Prediction of Gestational Diabetes by Measuring the Levels of Pregnancy Associated Plasma Protein-A (PAPP-A) During Gestation Weeks 11-14.
Ramezani, S., Doulabi, M. A., Saqhafi, H., & Alipoor, M. (2020) · PubMed Central · Cited by 16
The Value of Total antioxidant Status and Serum Tumor Necrosis Factor-α Levels at 24–28 Weeks of Gestation in the Prediction of Optimal Treatment Protocol in Gestational Diabetes Mellitus
Özler, S., Oztas, E., Uygur, D., Ersoy, A. Ö., Ergin, M., Koca, C., Danışman, N., & Erkaya, S. (2015) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0035-1554623 · Cited by 16
Gestational diabetes mellitus is rare in primigravida Pakistani women
Jawa, A., Raza, F., Qamar, K., Jawad, A., & Akram, J. (2011) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.83404 · Cited by 15
Shape Information in Repeated Glucose Curves during Pregnancy Provided Significant Physiological Information for Neonatal Outcomes
Frøslie, K. F., Røislien, J., Qvigstad, E., Godang, K., Bollerslev, J., Henriksen, T., & Veierød, M. B. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090798 · Cited by 15
“The HAPO study extended the Pedersen hypothesis about how maternal hyperglycemia affects the foetus [13] to the normalglycaemic range, thereby giving rise to a comprehensive debate about the GDM diagnosis [11,43–47].”
Method
Lifestyle interventions for the treatment of women with gestational diabetes
Brown, J., Alwan, N. A., West, J., Brown, S. C., McKinlay, C. J. D., Farrar, D., & Crowther, C. A. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011970 · Cited by 16
Excessive gestational weight gain in early pregnancy and insufficient gestational weight gain in middle pregnancy increased risk of gestational diabetes mellitus
Yin, A., Tian, F., Wu, X., Chen, Y., Liu, K., Tong, J., Guan, X., Zhang, H., Wu, L., & Niu, J. (2022) · Chinese Medical Journal · doi:10.1097/cm9.0000000000001972 · Cited by 15
Enhancing gestational diabetes mellitus risk assessment and treatment through GDMPredictor: a machine learning approach
Xing, J., Dong, K., Liu, X., Ma, J., Yuan, E., Zhang, L., & Yang, F. (2024) · Journal of Endocrinological Investigation · doi:10.1007/s40618-024-02328-z · Cited by 15
“GDM is associated with various adverse maternal and fetal outcomes, including preeclampsia, preterm birth, macrosomia, and neonatal hypoglycemia [2].”
Background
Does Maternal Body Mass Index Influence Treatment Effect in Women with Mild Gestational Diabetes?
Mele, L., Landon, M. B., Spong, C. Y., Ramin, S. M., Wapner, R. J., Varner, M. W., Rouse, D. J., Thorp, J. M., Catalano, P., Harper, M., et al. (2014) · American Journal of Perinatology · doi:10.1055/s-0034-1374815 · Cited by 17
Prospective associations between maternal stress during pregnancy and fasting glucose with obstetric and neonatal outcomes
Horsch, A., Gilbert, L., Lanzi, S., Kang, J. S., Vial, Y., & Puder, J. J. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109795 · Cited by 15
A simplified diagnostic work-up for the detection of gestational diabetes mellitus in low resources settings: achievements and challenges
Putoto, G., Somigliana, E., Olivo, F., Ponte, S., Koroma, M. M., Citterio, F., Orsi, M., Pisani, E., Pilon, M., Manenti, F., et al. (2020) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-020-05708-x · Cited by 16
Elective induction of labor in women with gestational diabetes mellitus: an intervention that modifies the risk of cesarean section
Lando, M. B., Srebnik, N., Farkash, R., Ioscovich, A., Samueloff, A., & Grisaru‐Granovsky, S. (2014) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-014-3313-6 · Cited by 15
CHARACTERIZATION OF PSYCHOLOGICAL AND PHYSICAL DEVELOPMENT IN CHILDREN OF GESTATION DIABETES PREGNANCIES
NIKITINA, I. L., KONOPLYA, I. S., POLYANSKAYA, A. A., Сергеевна, Л. А., & Popova, P. (2017) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2017-9-14-20 · Cited by 15
Expression Profile of Diabetes-Related Genes Associated with Leukocyte Sirtuin 1 Overexpression in Gestational Diabetes
Mac‐Marcjanek, K., Zieleniak, A., Żurawska-Kliś, M., Cypryk, K., Woźniak, L. A., & Wójcik, M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123826 · Cited by 15
“Gestational diabetes mellitus (GDM), defined as a carbohydrate intolerance of varying severity with onset or first recognition during pregnancy, is one of the most common pregnancy complications, affecting between 3% and 17% of all pregnancies, depending on the population studied and the diagnostic criteria used [1].”
Background
Oral anti-diabetic pharmacological therapies for the treatment of women with gestational diabetes
Brown, J., Martis, R., Hughes, B., Rowan, J., & Crowther, C. A. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011967 · Cited by 15
STZ-induced gestational diabetes exposure alters PTEN/AKT/mTOR-mediated autophagy signaling pathway leading to increase the risk of neonatal hypoxic-ischemic encephalopathy
Gong, L., Jiang, S., Tian, J., Li, Y., Yu, W., Zhang, L., & Xiao, D. (2023) · Reproductive Toxicology · doi:10.1016/j.reprotox.2023.108494 · Cited by 14
Identification of a novel association for the WWOX/HIF1A axis with gestational diabetes mellitus (GDM)
Baryła, I., Płuciennik, E., Kośla, K., Wójcik, M., Zieleniak, A., Żurawska-Kliś, M., Cypryk, K., Woźniak, L. A., & Bednarek, A. K. (2021) · PeerJ · doi:10.7717/peerj.10604 · Cited by 14
“recognition during pregnancy that complicates 1–22% of all pregnancies, depending on the ethnic background of the study population and the diagnostic criteria used (Coustan et al., 2010; Jenum et al., 2012).”
Background
HbA1c at term delivery and adverse pregnancy outcome
Hong, J. G. S., Fadzleeyanna, M. Y. N., Omar, S. Z., & Tan, P. C. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-05000-7 · Cited by 16
Gestational Glucose Intolerance and Birth Weight–Related Complications
Maya, J., Selen, D. J., Thaweethai, T., Hsu, S. C., Godbole, D., Schulte, C. C. M., James, K. E., Sen, S., Kaimal, A. J., Hivert, M., et al. (2023) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000005278 · Cited by 13
Association between neutrophil-lymphocyte ratio and perinatal depressive symptoms among Chinese women
Zhang, Y. P., Mei, H., Xiao, H., Zhang, Y., Gao, W., Qi, H., & Zhang, J. (2022) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2022.111101 · Cited by 13
Incidence of gestational diabetes mellitus in the United Arab Emirates; comparison of six diagnostic criteria: The Mutaba’ah Study
Bashir, M. M., Ahmed, L. A., Elbarazi, I., Loney, T., Al‐Rifai, R. H., Alkaabi, J., & Al‐Maskari, F. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1069477 · Cited by 15
Preeclampsia mediates the association between shorter height and increased risk of preterm delivery
Morisaki, N., Ogawa, K., Urayama, K. Y., Sago, H., Sato, S., & Saito, S. (2017) · International Journal of Epidemiology · doi:10.1093/ije/dyx107 · Cited by 13
Comparison of the International Association of Diabetes in Pregnancy Study Group Criteria with the Old American Diabetes Association Criteria for Diagnosis of Gestational Diabetes Mellitus
Niroomand, M., Afsar, J., Hosseinpanah, F., Afrakhteh, M., Farzaneh, F., & Serahati, S. (2019) · Intern J Endocrinol Metab · doi:10.5812/ijem.88343 · Cited by 14
Is vaginal progesterone treatment associated with the development of gestational diabetes? A retrospective case–control study
Rosta, K., Ott, J., Kelemen, F., Temsch, W., Lahner, T., Reischer, T., Helmer, H., & Somogyi, A. (2018) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-018-4895-1 · Cited by 13
Association between Diabetes in Pregnancy and Shoulder Dystocia by Infant Birth Weight in an Era of Cesarean Delivery for Suspected Macrosomia
Abdelwahab, M., Frey, H. A., Lynch, C. D.-J., Klebanoff, M. A., Thung, S., Costantine, M. M., Landon, M. B., & Venkatesh, K. K. (2023) · American Journal of Perinatology · doi:10.1055/s-0043-1764206 · Cited by 12
Trends and burden of diabetes in pregnancy among Aboriginal and non-Aboriginal mothers in Western Australia, 1998–2015
Ahmed, M. A., Bailey, H. D., Pereira, G. F., White, S. W., Wong, K., & Shepherd, C. (2022) · BMC Public Health · doi:10.1186/s12889-022-12663-6 · Cited by 11
Advanced glycation end products increased placental vascular permeability of human BeWo cells via RAGE/NF-kB signaling pathway
Shi, Y., Qian, J., Zhang, Q., Hu, Y., Sun, D., & Jiang, L. (2020) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2020.04.058 · Cited by 12
Low-carbohydrate diet and maternal glucose metabolism in Chinese pregnant women
Chen, Q., Chen, Y., Wu, W., Tang, N., Wang, D., Chen, Y., Jin, J., & Cai, L. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520004092 · Cited by 14
“Considerable evidence showed a continuous positive relationship between fasting plasma glucose (FPG) and postprandial glucose with caesarean section, clinical neonatal hypoglycaemia and preeclampsia(6).”
Background
Effects of Implementing International Association of Diabetes and Pregnancy Study Groups Gestational Diabetes Screening on Pregnancy Outcomes at a Small Community Teaching Hospital
Gerome, J. M., Bucher, L. K. M., & Dogbey, G. Y. (2017) · Clinical Diabetes · doi:10.2337/cd16-0031 · Cited by 12
Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteria
Han, S., Crowther, C. A., & Middleton, P. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009037 · Cited by 12
Impact de la chirurgie bariatrique sur le pronostic obstétrical
Fumery, L., Pigeyre, M., Fournier, C., Arnalsteen, L., Rivaux, G., Subtil, D., & Deruelle, P. (2012) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2012.09.004 · Cited by 11
The Effect of the 50 g Glucose Challenge Test on The Thiol/Disulfide Homeostasis in Pregnancy
Mertoğlu, C., Günay, M., Siranli, G., Külhan, M., Gök, G., & Erel, Ö. (2018) · Fetal and Pediatric Pathology · doi:10.1080/15513815.2018.1453002 · Cited by 11
“Since GDM may result in serious complications in both pregnant women and their infants, it is crucial to make an early diagnosis by performing screening tests (3).”
Background
Characteristics of bone turnover markers in women with gestational diabetes mellitus
Zhang, J., Zhang, Y., Wang, J., & Fan, Y. (2019) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2019.12.013 · Cited by 11
Gestational diabetes and pregnancy outcome – do we have right diagnostic criteria?
Tomić, V., Petrović, O., Orlić, Ž. C., & Mandić, V. (2013) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2013.776530 · Cited by 11
‘Dealing with ambiguity’– the role of obstetricians in gestational diabetes mellitus
Persson, M., Hörnsten, Å., Winkvist, A., & Mogren, I. (2011) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/j.1600-0412.2011.01240.x · Cited by 11
“However, as the results from the HAPO study are being presented, evidence for consensus criteria for the diagnosis and screening of GDM increases (1,3,23,24).”
Postpartum human breast milk levels of neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9)/NGAL complex in normal and pregnancies complicated with insulin-dependent gestational diabetes mellitus. A prospective pilot case-control study
Metallinou, D., Lykeridou, A., Karampas, G., Liosis, G., Skevaki, C. L., Rizou, M., Papassotiriou, I., & Rizos, D. (2019) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443615.2019.1628191 · Cited by 11
Unifying the diagnosis of gestational diabetes mellitus: Introducing the NPRP criteria
Doi, S. A. R., Bashir, M., Sheehan, M. T., Onitilo, A. A., Chivese, T., Ibrahim, I., Beer, S. F., Furuya‐Kanamori, L., Abou‐Samra, A., & McIntyre, D. H. (2021) · Primary care diabetes · doi:10.1016/j.pcd.2021.08.006 · Cited by 12
Cord serum dipeptidyl‐peptidase 4 activity in gestational diabetes
Al‐Aissa, Z., Rosta, K., Hadarits, O., Harreiter, J., Zóka, A., Bancher‐Todesca, D., Patócs, A., Kiss, K., Sármán, B., Pusztai, P., et al. (2015) · European Journal of Clinical Investigation · doi:10.1111/eci.12397 · Cited by 11

Authors: Coustan, D. R., Lowe, L. P., Metzger, B. E., & Dyer, A. R.
Affiliations: Brown University (US)
Northwestern University (US)
ORCID: Coustan, Donald R.
Lowe, Lynn P.
Metzger, Boyd E.
Dyer, Alan R.
Venue: American Journal of Obstetrics and Gynecology
Publisher: Elsevier BV
Published: 2010-06
Volume: 202
Issue: 6
Pages: 654.e1-654.e6
ISSN: 0002-9378 (ISSN-L)
DOI: 10.1016/j.ajog.2010.04.006
PMC: PMC2897007
OpenAlex: W2063955121
Cited by: 398
References: 16
Citations by year: 2026: 14 · 2025: 32 · 2024: 20 · 2023: 28 · 2022: 41 · 2021: 25 · 2020: 30 · 2019: 27 · 2018: 20 · 2017: 30 · 2016: 25 · 2015: 23 · 2014: 25 · 2013: 17 · 2012: 12
FWCI: 24.86
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: American Journal of Obstetrics and Gynecology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (R01-HD34242, R01-HD34243)
National Center for Research Resources (M01-RR00048, M01-RR00080)
Eunice Kennedy Shriver National Institute of Child Health and Human Development
American Diabetes Association
Topics: Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: gestational diabetes mellitus, diagnostic criteria, HAPO study, oral glucose tolerance test, hyperglycemia, adverse pregnancy outcomes, large for gestational age, cesarean section, fetal insulin
MeSH terms: Blood Glucose, Female, Glucose Tolerance Test, Humans, Insulin, Predictive Value of Tests, Pregnancy, Pregnancy Outcome, Odds Ratio, Diabetes, Gestational

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: paving the way for new diagnostic criteria for gestational diabetes mellitus

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks