CoChat
Sign Up
Cited by 47Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesSexual Differentiation and DisordersSexual function and dysfunction studies

Turner's syndrome and other forms of congenital hypogonadism impair quality of life and sexual function

Ros, Cristina, Alobid, Isam, Balasch, Juan, Mullol, Joaquim, Castelo-Branco, Camil·2013·American Journal of Obstetrics and Gynecology
DOI 10.1016/j.ajog.2013.01.011
Open this paper in CoChat — free account

Abstract

Objective We sought to assess the burden of Turner's syndrome (TS) and other congenital hypogonadisms (OCH) on quality of life (QOL) and sexual function.Study design An observational study was undertaken in a gynecological endocrinology unit of a teaching hospital. Three cohorts of women aged 20-50 years were compared: 26 TS patients, 21 women with OCH and wild-type karyotype, and 41 healthy age-matched women who were included as controls. All subjects filled out the Medical Outcome Study Short Form (SF-36) and the Female Sexual Function Index.Results TS subjects had significantly worse QOL scores in physical functioning (P = .026) and role physical functioning (P = .032) whereas OCH showed significantly worse scores in physical functioning (P = .027) and bodily pain (P = .025) compared to controls. In all, 80% of OCH and 50% of TS patients declared sexual activity. Sexually active TS patients had poorer arousal outcomes (P = .009) and OCH women showed significantly worse scores in arousal (P = .002), orgasm (P = .007), pain (P = .001), and Female Sexual Function Index total score (P = .004) compared with healthy controls. No differences between sexually active and inactive TS women were found in SF-36 scores, clinical characteristics, or anthropomorphic characteristics.Conclusion TS and OCH subjects presented impaired physical domains in QOL. Women with TS are less likely to be involved in sexual activity, arousal dysfunctions being their main symptom. Conversely, arousal, orgasm, pain, and total score were significantly affected in OCH subjects.

Integrity signals

Registry

Crossref · 10.1016/j.ajog.2013.01.011

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Despite having normal sex drive/libido, individuals with TS are less likely to be married or in relationships compared to women of the same age.

    “Despite having normal sex drive/libido, individuals with TS are less likely to be married or in relationships as compared to women of the same age.371,372,569,570”

    From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [569]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Ros, C., Alobid, I., Balasch, J., Mullol, J., & Castelo-Branco, C.
Affiliations
  • Hospital Clínic de Barcelona (ES)
  • Universitat de Barcelona (ES)
ORCID
Venue
American Journal of Obstetrics and Gynecology
Publisher
Elsevier BV
Published
2013-06
Volume
208
Issue
6
Pages
484.e1-484.e6
ISSN
0002-9378 (ISSN-L)
DOI
10.1016/j.ajog.2013.01.011
OpenAlex
W1969443369
Cited by
47
References
32
Citations by year
2026: 1 · 2025: 5 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 6 · 2018: 4 · 2017: 3 · 2016: 3 · 2015: 6 · 2014: 2 · 2013: 2
FWCI
2.87
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • American Journal of Obstetrics and Gynecology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Keywords
Turner syndrome, congenital hypogonadism, quality of life, female sexual function, orgasm, sexual activity, physical function, bodily pain, karyotype
MeSH terms
Adult, Female, Humans, Hypogonadism, Middle Aged, Quality of Life, Surveys and Questionnaires, Sexual Behavior, Turner Syndrome, Cohort Studies, Sexual Dysfunctions, Psychological, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review