Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 292

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

The female urinary microbiome in urgency urinary incontinence

Open access
Pearce, Meghan M., Zilliox, Michael J., Rosenfeld, Amy B., Thomas-White, Krystal J., Richter, Holly E., Nager, Charles W., Visco, Anthony G., Nygaard, Ingrid E., Barber, Matthew D., Schaffer, Joseph, Moalli, Pamela, Sung, Vivian W., Smith, Ariana L., Rogers, Rebecca, Nolen, Tracy L., Wallace, Dennis, Meikle, Susan F., Gai, Xiaowu, Wolfe, Alan J., Brubaker, Linda·2015·American Journal of Obstetrics and Gynecology
DOI 10.1016/j.ajog.2015.07.009
Open this paper in CoChat — free account

Abstract

Objectives To characterize the urinary microbiota in women planning treatment for urgency urinary incontinence and to describe clinical associations with urinary symptoms, urinary tract infection and treatment outcomes. Study Design Catheterized urine samples were collected from female multi-site randomized trial participants without clinical evidence of urinary tract infection and 16S rRNA gene sequencing was used to dichotomize participants as either DNA sequence-positive or sequence-negative. Associations with demographics, urinary symptoms, urinary tract infection risk, and treatment outcomes were determined. In sequence-positive samples, microbiotas were characterized on the basis of their dominant microorganisms. Results Over half [51.1% (93/182)] of the participants’ urine samples were sequence-positive. Sequence-positive participants were younger (55.8 vs. 61.3, p=0.0007), had a higher body mass index (33.7 vs. 30.1, p=0.0009), had a higher mean baseline daily urgency urinary incontinence episodes (5.7 vs. 4.2, p<0.0001), responded better to treatment (decrease in urgency urinary incontinence episodes −4.4 vs. −3.3, p=0.0013) and were less likely to develop urinary tract infection (9% vs. 27%, p=0.0011). In sequence-positive samples, eight major bacterial clusters were identified; seven clusters were dominated by a single genus, most commonly Lactobacillus (45%) or Gardnerella (17%), but also other taxa (25%). The remaining cluster had no dominant genus (13%). Conclusions DNA sequencing confirmed urinary bacterial DNA in many women without signs of infection and with urgency urinary incontinence. Sequence status was associated with baseline urgency urinary incontinence episodes, treatment response and post-treatment urinary tract infection risk.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.ajog.2015.07.009

Cites

17 of 17 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 17 references

Cited by

See all 292

Metadata

Authors
Pearce, M. M., Zilliox, M. J., Rosenfeld, A. B., Thomas-White, K. J., Richter, H. E., Nager, C. W., Visco, A. G., Nygaard, I. E., Barber, M. D., Schaffer, J., Moalli, P., Sung, V. W., Smith, A. L., Rogers, R., Nolen, T. L., Wallace, D., Meikle, S. F., Gai, X., Wolfe, A. J., & Brubaker, L.
Venue
American Journal of Obstetrics and Gynecology
Publisher
Elsevier BV
Published
2015-09
Volume
213
Issue
3
Pages
347.e1-347.e11
ISSN
0002-9378 (ISSN-L)
DOI
10.1016/j.ajog.2015.07.009
OpenAlex
W1834656240
Cited by
292
References
17
FWCI
17.43
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: The female urinary microbiome in urgency urinary incontinence. https://app.cochat.ai/papers/10.1016/j.ajog.2015.07.009
The paper
Pearce, M. M., Zilliox, M. J., Rosenfeld, A. B., Thomas-White, K. J., Richter, H. E., Nager, C. W., Visco, A. G., Nygaard, I. E., Barber, M. D., Schaffer, J., Moalli, P., Sung, V. W., Smith, A. L., Rogers, R., Nolen, T. L., Wallace, D., Meikle, S. F., Gai, X., Wolfe, A. J., & Brubaker, L. (2015). The female urinary microbiome in urgency urinary incontinence. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/j.ajog.2015.07.009

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.