The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
What is the placenta?
Open accessAbstract
Discarded at birth, the placenta is a highly complex and fascinating organ. During the course of a pregnancy, it acts as the lungs, gut, kidneys, and liver of the fetus. The placenta also has major endocrine actions that modulate maternal physiology and metabolism and provides a safe and protective milieu in which the fetus can develop. The human placenta undergoes dramatic transformations in form and function between the first trimester, when organogenesis occurs, and the remainder of pregnancy that reflect evolutionary responses to changing oxygen concentrations in the earth's atmosphere. Recent research indicates a more interactive dialogue between the placenta and the maternal tissues than previously recognized. The endometrial glands provide histotrophic support during the first weeks of pregnancy, and the placenta appears able to stimulate its own development by up-regulating gland activity in response to endocrine signals. Extravillous trophoblast cells migrate from the placenta into the uterine wall, in which they interact with cells of the maternal innate immune system. These interactions have a physiological, rather than a classical immunological, outcome and most probably mediate remodeling of the uterine spiral arteries that supply the placenta. Furthermore, deportation of aggregates of transcriptionally active trophoblast nuclei, and the release of exosomes carrying microribonucleic acids challenge our perceptions of fetal-maternal signaling and where the placental interface actually lies. Here we reconsider definitions of the placenta in the light of these recent advances.
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Cites
Burton, G. J., Woods, A. W., Jauniaux, E., & Kingdom, J. C. P. (2009) · Placenta · doi:10.1016/j.placenta.2009.02.009 · Cited by 1,188
Self-citationComparative morphogenesis of the fetal membranes and accessory uterine structures
Mossman, H. W. (1991) · Placenta · doi:10.1016/0143-4004(91)90504-9 · Cited by 499
Sarker, S., Scholz-Romero, K., Perez, A., Illanes, S. E., Mitchell, M. D., Rice, G. E., & Salomon, C. (2014) · Journal of Translational Medicine · doi:10.1186/1479-5876-12-204 · Cited by 411
The influence of the intrauterine environment on human placental development
Burton, G. J., Jauniaux, E., & Charnock-Jones, D. S. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.082764gb · Cited by 307
Self-citationComparative Placentation: Structures, Functions and Evolution
Wooding, P., & Burton, G. (2008) · doi:10.1007/978-3-540-78797-6 · Cited by 228
Self-citationMaternal influences on fetal microbial colonization and immune development
Romano-Keeler, J., & Weitkamp, J.-H. (2015) · Pediatric Research · doi:10.1038/pr.2014.163 · Cited by 212
Rajakumar, A., Cerdeira, A. S., Rana, S., Zsengeller, Z., Edmunds, L., Jeyabalan, A., Hubel, C. A., Stillman, I. E., Parikh, S. M., & Karumanchi, S. A. (2012) · Hypertension · doi:10.1161/hypertensionaha.111.182170 · Cited by 180
Biological Roles of Uterine Glands in Pregnancy
Spencer, T. (2014) · Seminars in Reproductive Medicine · doi:10.1055/s-0034-1376354 · Cited by 115
Jauniaux, E. R. M., Cindrová‐Davies, T., Johns, J., Dunster, C., Hempstock, J., Kelly, F. J., & Burton, G. J. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031332 · Cited by 111
Self-citationThe role of the maternal immune system in the regulation of human birthweight
Moffett, A., Hiby, S. E., & Sharkey, A. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0071 · Cited by 96
Cited by
Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?
Pique-Regi, R., Romero, R., Tarca, A. L., Luca, F., Xu, Y., Alazizi, A., Leng, Y., Hsu, C.-D., & Gomez-Lopez, N. (2020) · eLife · doi:10.7554/elife.58716 · Cited by 283
The Placental Barrier: the Gate and the Fate in Drug Distribution
Tetro, N., Moushaev, S., Rubinchik-Stern, M., & Eyal, S. (2018) · Pharmaceutical Research · doi:10.1007/s11095-017-2286-0 · Cited by 145
The first prior: From co-embodiment to co-homeostasis in early life
Ciaunica, A., Constant, A., Preissl, H., & Fotopoulou, K. (2021) · Consciousness and Cognition · doi:10.1016/j.concog.2021.103117 · Cited by 105
Modelling female physiology from head to Toe: impact of sex hormones, menstrual cycle, and pregnancy
Abo, S., Smith, D., Stadt, M., & Layton, A. (2022) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2022.111074 · Cited by 35
Mitochondrial transformations in the aging human placenta
Bartho, L. A., Fisher, J. J., Cuffe, J. S. M., & Perkins, A. V. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00354.2020 · Cited by 32
Metadata
- Authors
- Burton, G. J., & Jauniaux, E.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 213
- Issue
- 4
- Pages
- S6.e1-S6.e4
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2098835730
- Cited by
- 342
- References
- 11
- FWCI
- 16.86
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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