Dual Use of Nicotine and Cannabis Through Vaping Among Adolescents
Open accessAbstract
Introduction This study seeks to identify adolescent nicotine and cannabis vaping patterns and the characteristics of those adolescents who comprised each pattern. Methods This prospective longitudinal survey study measured the relationship between nicotine and cannabis vaping among 1,835 adolescents from 4 public high schools outside of Philadelphia, Pennsylvania. Adolescents completed in-classroom surveys, including questions of lifetime and past 30-day nicotine and cannabis vaping, at Wave 1 (fall 2016, ninth grade) and 6-month intervals for the following 36 months (fall 2019, 12th grade). Data were analyzed in 2021. Results A sequential processes growth mixture model revealed 4 latent conjoint classes of nicotine and cannabis vaping: early, declining dual use (Class 1: n=259); rapidly increasing dual use (Class 2: n=128); later, slower dual use (Class 3: n=313); and no use (Class 4: n=1,136). Increased odds of belonging to Class 1 and Class 2 versus belonging to Class 4 were significantly associated with cigarette smoking (OR=3.71, OR=2.21), alcohol use (OR=2.55, OR=4.39), peer vaping (OR=1.24, OR=1.20), sensation seeking (OR=1.03, OR=1.11), positive E-cigarette expectations (OR=1.21, OR=1.17), and cigar smoking (OR=2.39 Class 2 only). Increased odds of belonging to Class 3 versus Class 4 were significantly associated with alcohol use (OR=1.66), perceived benefits of E-cigarette use (OR=1.03), positive E-cigarette expectations (OR=1.08), depressive symptoms (OR=1.02), and sensation seeking (OR=1.03). Conclusions From middle to late adolescence, vaping of nicotine and cannabis develop in close parallel. Regulatory policy and prevention interventions should consider the interplay between these 2 substances during this period of adolescence.
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Recent evidence suggests e-cigarette use and cannabis use develop in close parallel from middle to late adolescence.
“recent evidence suggests that e-cigarette use and cannabis use develop in close parallel from middle to late adolescence [242]”
From Consequences of adolescent drug use (2023) · cites this paper as [242]
The Discussion reports co-development of nicotine and cannabis vaping from middle to late adolescence and describes their use as parallel. The claim broadens this to cannabis use generally, whereas the study assessed cannabis vaping specifically. (LLM, conf=0.84)
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- Authors
- Moustafa, A. F., Rodriguez, D., Pianin, S. H., Testa, S. M., & Audrain-McGovern, J. E.
- Affiliations
- New York Medical College (US)
- La Salle University (US)
- University of Pennsylvania (US)
- Corresponding author
- Audrain-McGovern, Janet E.
- Venue
- American Journal of Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2022-07
- Volume
- 63
- Issue
- 1
- Pages
- 60-67
- ISSN
- 0749-3797 (ISSN-L)
- PMC
- PMC9232951
- OpenAlex
- W4220759881
- Cited by
- 26
- References
- 52
- Citations by year
- 2026: 8 · 2025: 5 · 2024: 7 · 2023: 6
- FWCI
- 2.72
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Preventive Medicine (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (RO1 CA202262)
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Sociology and Political Science › Impact of Technology on Adolescents
- Keywords
- vaping, youth vaping, cannabis vaping, nicotine vaping, cigarette smoking, alcohol consumption, sensation seeking, depressive symptoms, adolescent substance use
- MeSH terms
- Vaping, Adolescent, Cannabis, Humans, Nicotine, Prospective Studies, Philadelphia, Electronic Nicotine Delivery Systems
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