Self-Measurement and Self-Titration in HypertensionA Pilot Telemedicine Study
Abstract
BACKGROUND: Because of poor patient compliance and clinical inertia, hypertension control rates remain poor. Home blood-pressure measurements (HBPM) improve compliance of patients and achievement of blood pressure (BP) targets. However, few studies have evaluated self-BP management by patients. METHODS: In a multicenter, prospective, single-group, open-label pilot study of 111 patients whose hypertension was uncontrolled despite monotherapy, we studied satisfaction with, and feasibility of, HBPM and self-titration of antihypertensive treatment using telemedicine for compliance, efficacy, and safety. After education (protocol, action plan, and use of the HBPM device), patients performed a sequence of HBPM every 2 weeks for 8 weeks. Following a stepwise approach, treatment was increased by the patient at weeks 4 and 6 if average HBPM values exceeded predefined limits. For each titration, the patient informed the Core Center by telemedicine, but BP values were transferred automatically. RESULTS: Overall, 80% of patients were satisfied (58%) or very satisfied (23%) with the program (95% confidence interval, 73% to 87%). Regarding compliance, 78% of patients fully complied with self-measurement, and just over 71% titrated their treatment adequately. Physicians were satisfied (52%) or very satisfied (22%) with the program. Between the first and final visits (at week 8), office systolic/diastolic BP (mean +/- SD) decreased significantly from 151 +/- 9/91 +/- 6 to 143 +/- 13/84 +/- 11 mmHg. During the trial, HBPM (mean +/- SD) decreased significantly from 149 +/- 13/86 +/- 12 to 138 +/- 16/81 +/- 10 mmHg. No significant safety issues were reported. CONCLUSIONS: This innovative approach to the management of hypertension, combining self-measurement and self-titration, is feasible, well-accepted by both patients and physicians, and safe.
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HBPT may achieve more satisfactory hypertension control rates.
“and to achieve more satisfactory hypertension control rates [57,112–115]”
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- Authors
- BOBRIE, G., POSTELVINAY, N., DELONCA, J., & CORVOL, P.
- Affiliations
- Hôpital Européen Georges-Pompidou (FR)
- Bristol-Myers Squibb (France) (FR)
- Corresponding author
- BOBRIE, G
- Venue
- American Journal of Hypertension
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-12
- Volume
- 20
- Issue
- 12
- Pages
- 1314-1320
- ISSN
- 0895-7061 (ISSN-L)
- OpenAlex
- W2024198186
- Cited by
- 68
- References
- 27
- Citations by year
- 2025: 3 · 2024: 1 · 2021: 2 · 2020: 2 · 2019: 4 · 2018: 2 · 2017: 1 · 2016: 2 · 2015: 7 · 2014: 4 · 2013: 4 · 2012: 9
- FWCI
- 3.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Keywords
- hypertension, home blood pressure monitoring, self-titration, telemedicine, antihypertensive therapy, medication adherence, uncontrolled hypertension, patient satisfaction, physician satisfaction, blood pressure control
- MeSH terms
- Aged, Blood Pressure Determination, Female, Humans, Hypertension, Male, Middle Aged, Patient Compliance, Pilot Projects, Prospective Studies, Self Care, Telemedicine
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