CoChat
Sign Up
Cited by 109Clinical Laboratory Practices and Quality ControlLGBTQ Health, Identity, and PolicyHormonal and reproductive studies

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Interpreting Laboratory Results in Transgender Patients on Hormone Therapy

Roberts, Tiffany K., Kraft, Colleen S., French, Deborah, Ji, Wuyang, Wu, Alan H.B., Tangpricha, Vin, Fantz, Corinne R.·2014·The American Journal of Medicine
DOI 10.1016/j.amjmed.2013.10.009
Open this paper in CoChat — free account

Abstract

Background Clinical guidelines recommend laboratory monitoring of transgender persons on cross-sex hormone therapy, but gender-specific reference intervals leave clinicians with the dilemma of deciding what is "normal" for each patient. The goal of this study was to identify consistent changes in measurands with hormone therapy and determine which reference interval is appropriate.Methods Laboratory data were abstracted from the medical records of 55 male-to-female patients on hormone therapy and compared with 20 male and 20 female nontransgender subjects.Results Hemoglobin, hematocrit, and low-density lipoprotein resembled female values (P < .005), while alkaline phosphatase, potassium, and creatinine resembled male values (P < .05). Triglycerides were higher (P < .005) than either the male or female groups. The remainder of the measurands showed no differences.Conclusions Use of correct reference intervals in interpreting laboratory results reduces the risk of testing-related diagnostic error. Preliminary data suggest that new reference intervals need to be established for transgender patients.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.amjmed.2013.10.009

Cites

13 of 13 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 13 references

Cited by

Sorted by citations

Related

See all

Metadata

Authors
Roberts, T. K., Kraft, C. S., French, D., Ji, W., Wu, A. H. B., Tangpricha, V., & Fantz, C. R.
Affiliations
  • Emory University (US)
  • University of California, San Francisco (US)
  • San Francisco General Hospital (US)
Corresponding author
Roberts, Tiffany K.
ORCID
Venue
The American Journal of Medicine
Publisher
Elsevier BV
Published
2014-02
Volume
127
Issue
2
Pages
159-162
ISSN
0002-9343 (ISSN-L)
DOI
10.1016/j.amjmed.2013.10.009
OpenAlex
W2002613869
Cited by
109
References
13
Citations by year
2026: 4 · 2025: 6 · 2024: 11 · 2023: 12 · 2022: 11 · 2021: 8 · 2020: 13 · 2019: 10 · 2018: 8 · 2017: 17 · 2016: 5 · 2015: 3 · 2014: 1
FWCI
2.08
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • The American Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
  • Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Keywords
transgender patients, gender-affirming hormone therapy, laboratory reference intervals, laboratory monitoring, hemoglobin, hematocrit, low-density lipoprotein, alkaline phosphatase, triglycerides, diagnostic errors
MeSH terms
Adult, Aged, Alkaline Phosphatase, Creatinine, Diagnostic Errors, Female, Hematocrit, Hemoglobins, Humans, Cholesterol, LDL, Male, Middle Aged, Potassium, Reference Values, Gonadal Steroid Hormones, Triglycerides, Biomarkers, Gender-Affirming Procedures, Transgender Persons

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review