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The impact of anxiety and depression on outpatients with asthma
Open accessAbstract
Background Anxiety and depression may frequently affect patients with asthma. However, the findings of several studies are partially conflicting and conducted in selected cohorts. Objective To investigate the effect of anxiety and depression in a group of outpatients with asthma. Methods This cross-sectional, real-life study included 263 patients (109 males; mean age, 39.2 years) with asthma. Clinical examination, lung function, fractional exhaled nitric oxide measurement, Asthma Control Test (ACT) score, asthma control grade, perception of symptoms by visual analog scale, and Hospital Anxiety and Depression Scale (HADS) questionnaires were evaluated. Results Globally, 97 patients (36.9%) had anxiety, and 29 (11%) had depression. Of these patients, 71 had combined anxiety and depression. Anxiety and depression were associated with poor asthma control (P =.007 and .02, respectively). Patients with depression had higher body mass indexes (P =.002). Anxiety and depression were associated with lower ACT scores (P < .001 for both). The scores on the anxiety and depression subscales of HADS were moderately related (r = 0.57). Conclusions The present real-life study indicates that anxiety and depression are common and relevant comorbidities in asthmatic outpatients and are associated with uncontrolled asthma and lower ACT scores. Thus, assessment of comorbid mental disorders should be performed in common practice.
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“Some of the features of asthma overlap with symptoms of anxiety and the association between asthma and anxiety has been reported extensively in the scientific literature (Brew, Lundholm, Gong, Larsson & Almqvist, 2018;Brew, Lundholm, Viktorin, Lichtenstein, Larsson & Almqvist, 2018;Ciprandi, Schiavetti, Rindone & Ricciardolo, 2015).”
From Exposure‐based cognitive behavior therapy for anxiety related to asthma: A feasibility study with multivariate baseline design. (2020) · cites this paper as Ciprandi, Schiavetti, Rindone & Ricciardolo, 2015
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Metadata
- Authors
- Ciprandi, G., Schiavetti, I., Rindone, E., & Ricciardolo, F. L. M.
- Affiliations
- Ospedale Policlinico San Martino (IT)
- University of Genoa (IT)
- University of Turin (IT)
- Corresponding author
- Ciprandi, Giorgio
- Venue
- Annals of Allergy, Asthma & Immunology
- Publisher
- Elsevier BV
- Published
- 2015-11
- Volume
- 115
- Issue
- 5
- Pages
- 408-414
- ISSN
- 1081-1206 (ISSN-L)
- OpenAlex
- W2097414539
- Cited by
- 177
- References
- 47
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 15 · 2023: 11 · 2022: 17 · 2021: 21 · 2020: 53 · 2019: 14 · 2018: 10 · 2017: 8 · 2016: 8 · 2015: 1
- FWCI
- 6.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of Allergy Asthma & Immunology (publishedVersion)
- PubMed (publishedVersion)
- CINECA IRIS Institutial Research Information System (University of Genoa) (submittedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- asthma, anxiety, depression, comorbidities, asthma control, Asthma Control Test, outpatients, body mass index, mental health screening
- MeSH terms
- Adult, Anxiety, Asthma, Cross-Sectional Studies, Depression, Depressive Disorder, Female, Humans, Male, Outpatients, Severity of Illness Index, Visual Analog Scale
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