Are psychiatric disorders associated with worse asthma control and quality of life in asthma patients?
Open accessAbstract
Background Achieving good asthma control has become the major goal of asthma treatment. Studies have reported a high rate of psychiatric disorders among asthma patients, though the impact of these disorders on asthma control and quality of life remains unexplored. This study evaluated the prevalence of psychiatric disorders in 406 adult asthma patients, and associations between psychiatric status, levels of asthma control, and asthma-related quality of life.Methods Consecutive asthma patients presenting to the asthma clinic underwent a brief, structured psychiatric interview, completed the Asthma Control Questionnaire (ACQ) and Asthma Quality of Life Questionnaire (AQLQ), and reported the frequency of bronchodilator use in the past week. All patients underwent standard pulmonary function testing.Results A total of 34% (n=136) of patients had one or more psychiatric diagnosis, including major depression (15%), minor depression (5%), dysthymia (4%), panic disorder (12%), generalized anxiety disorder (5%), and social phobia (4%). Though there were no differences in pulmonary function, patients with versus without psychiatric disorders had worse ACQ and AQLQ scores and reported greater bronchodilator use, independent age, sex and asthma severity.Conclusions Results suggest that psychiatric disorders are prevalent among asthmatics and are associated with worse asthma control and quality of life. Physicians should be aware of the potential risk of poorer asthma control and functional impairment in this population.
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Psychological dysfunction is often unrecognized in primary care, despite being significantly associated with poor asthma outcomes, including asthma control and QoL.
“Psychological dysfunction is often unrecognized in primary care, despite being significantly associated with poor asthma outcomes, including asthma control and QoL.8,12,13”
From A systematic review of psychological, physical health factors, and quality of life in adult asthma (2019) · cites this paper as [12]
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- Authors
- Lavoie, K. L., Cartier, A., Labrecque, M., Bacon, S. L., Lemière, C., Malo, J.-L., Lacoste, G., Barone, S., Verrier, P., & Ditto, B.
- Affiliations
- Université du Québec à Montréal (CA)
- Hôpital du Sacré-Cœur de Montréal (CA)
- Montreal Heart Institute (CA)
- Corresponding author
- Lavoie, Kim L.
- ORCID
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2005-10
- Volume
- 99
- Issue
- 10
- Pages
- 1249-1257
- ISSN
- 0954-6111 (ISSN-L)
- OpenAlex
- W2108940923
- Cited by
- 201
- References
- 45
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 10 · 2023: 8 · 2022: 9 · 2021: 4 · 2020: 9 · 2019: 12 · 2018: 8 · 2017: 6 · 2016: 14 · 2015: 14 · 2014: 16 · 2013: 9 · 2012: 12
- FWCI
- 6.59
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Respiratory Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
- Keywords
- asthma, mental illness, asthma control, quality of life, depression, anxiety disorders, panic disorder, dysthymia, social anxiety disorder, bronchodilator use, prevalence, lung function
- MeSH terms
- Adult, Asthma, Mental Disorders, Bronchodilator Agents, Female, Forced Expiratory Volume, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Prevalence
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