The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
Anesthesia for Major Surgery in the Neonate
Abstract
Perioperative risk of morbidity and mortality for neonates is significantly higher than that for older children and adults. At particular risk are neonates born prematurely, neonates with major or severe congenital heart disease, and neonates with pulmonary hypertension. Presently no consensus exists regarding the safest anesthetic regimen for neonates. Regional anesthesia appears to be safe, but does not reduce the overall risk of postoperative apnea. Former preterm infants require postoperative observation for apnea. The anesthesiologist caring for the neonate for major surgery should be knowledgeable of the unique physiology of the neonate and maintain the highest level of vigilance throughout.
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Due to poor ventricular compliance, excessive fluid infusion may put the neonatal heart at risk of overdistension and heart failure.
“due to poor ventricular compliance, excessive fluid infusion may put the neonatal heart at risk of overdistension and heart failure (5).”
From Innovative wearable technology for continuous echocardiographic monitoring: first-in-neonate case report (2025) · cites this paper as [5]
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Cites
Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort
Wilder, R. T., Flick, R. P., Šprung, J., Katusic, S. K., Barbaresi, W. J., Mickelson, C., Gleich, S. J., Schroeder, D. R., Weaver, A. L., & Warner, D. O. (2009) · Anesthesiology · doi:10.1097/01.anes.0000344728.34332.5d · Cited by 1,367
Sun, L. S., Li, G., Miller, T. L. K., Salorio, C., Byrne, M. W., Bellinger, D. C., Ing, C., Park, R., Radcliffe, J., Hays, S. R., et al. (2016) · JAMA · doi:10.1001/jama.2016.6967 · Cited by 949
A STUDY OF THE DEATHS ASSOCIATED WITH ANESTHESIA AND SURGERY
Beecher, H. K., & Todd, D. P. (1954) · Annals of Surgery · doi:10.1097/00000658-195407000-00001 · Cited by 771
McCann, M. E., de Graaff, J. C., Dorris, L., Disma, N. M., Withington, D. E., Bell, G., Grobler, A. C., Stargatt, R., Hunt, R. W., Sheppard, S., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32485-1 · Cited by 757
Anand, K. J. S., Sippell, W. G., & Aynsley-Green, A. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91907-6 · Cited by 751
Bhananker, S. M., Ramamoorthy, C., Geiduschek, J. M., Posner, K. L., Domino, K. B., Haberkern, C. M., Campos, J. S., & Morray, J. P. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000268712.00756.dd · Cited by 717
Oxygen Saturation and Outcomes in Preterm Infants
The BOOST II United Kingdom, A. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1302298 · Cited by 507
Postoperative Apnea in Former Preterm Infants after Inguinal Herniorrhaphy
Coté, C. J., Zaslavsky, A. M., Downes, J. J., Kurth, C. D., Welborn, L. G., Warner, L. O., & Malviya, S. V. (1995) · Anesthesiology · doi:10.1097/00000542-199504000-00002 · Cited by 505
Anesthesia-related Cardiac Arrest in Children
Morray, J. P., Geiduschek, J. M., Ramamoorthy, C., Haberkern, C. M., Hackel, A., Caplan, R. A., Domino, K. B., Posner, K. L., & Cheney, F. W. (2000) · Anesthesiology · doi:10.1097/00000542-200007000-00007 · Cited by 488
Anand, K. J. S., Sippell, W. G., & Green, A. A. (1987) · The Lancet · doi:10.1016/s0140-6736(87)90065-1 · Cited by 481
Anesthesia-Related Cardiac Arrest in Children with Heart Disease
Ramamoorthy, C., Haberkern, C. M., Bhananker, S. M., Domino, K. B., Posner, K. L., Campos, J. S., & Morray, J. P. (2010) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181c9f927 · Cited by 425
Complications in Pediatric Regional Anesthesia
Walker, B. J., Long, J. B., Sathyamoorthy, M., et al. (2018) · Anesthesiology · doi:10.1097/aln.0000000000002372 · Cited by 377
Apnea after Awake Regional and General Anesthesia in Infants
Davidson, A. J., Morton, N. S., Arnup, S. J., et al. (2015) · Anesthesiology · doi:10.1097/aln.0000000000000709 · Cited by 292
Volume-targeted versus pressure-limited ventilation in neonates
Klingenberg, C., Wheeler, K., McCallion, N., et al. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003666.pub4 · Cited by 290
Perioperative Cardiac Arrests in Children between 1988 and 2005 at a Tertiary Referral Center
Flick, R. P., Šprung, J., Harrison, T. E., et al. (2007) · Anesthesiology · doi:10.1097/00000542-200702000-00009 · Cited by 269
Clinical Practice Guideline: Maintenance Intravenous Fluids in Children
Feld, L. G., Neuspiel, D. R., Foster, B. A., Leu, M. G., Garber, M. D., Austin, K. L., Basu, R. K., Conway, E. E., Fehr, J. J., Hawkins, C., et al. (2018) · PEDIATRICS · doi:10.1542/peds.2018-3083 · Cited by 255
Guidelines for assessing appropriateness of pediatric transfusion
Roseff, S. D., Luban, N. L. C., & Manno, C. S. (2002) · Transfusion · doi:10.1046/j.1537-2995.2002.00208.x · Cited by 248
Postoperative Mortality in Children After 101,885 Anesthetics at a Tertiary Pediatric Hospital
van der Griend, B. F., Lister, N. A., McKenzie, I., et al. (2011) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e318213be52 · Cited by 242
Ceelie, I., de Wildt, S. N., van Dijk, M., et al. (2013) · JAMA · doi:10.1001/jama.2012.148050 · Cited by 238
Postoperative Apnea in Preterm Infants
Kurth, C. D., Spitzer, A. R., Broennle, A. M., et al. (1987) · Anesthesiology · doi:10.1097/00000542-198704000-00006 · Cited by 231
Chambers, N. A., Ramgolam, A., Sommerfield, D. L., et al. (2017) · Anaesthesia · doi:10.1111/anae.14113 · Cited by 171
Oxygen Saturation Target Range for Extremely Preterm Infants
Manja, V., Lakshminrusimha, S., & Cook, D. J. (2015) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2014.3307 · Cited by 158
How do pediatric anesthesiologists define intraoperative hypotension?
Nafiu, O. O., Voepel‐Lewis, T., MORRIS, M., et al. (2009) · Pediatric Anesthesia · doi:10.1111/j.1460-9592.2009.03140.x · Cited by 133
Fentanyl-Air-Oxygen Anesthesia for Ligation of Patent Ductus Arteriosus in Preterm Infants
Robinson, S., & Gregory, G. A. (1981) · Anesthesia & Analgesia · doi:10.1213/00000539-198105000-00011 · Cited by 121
Pediatric Formulas for the Anesthesiologist
Cole, F. (1957) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1957.04030070084009 · Cited by 113
Fentanyl-Air-Oxygen Anesthesia for Ligation of Patent Ductus Arteriosus in Preterm Infants
Robinson, S., Gregory, G. A., & Smith, R. M. (1982) · Survey of Anesthesiology · doi:10.1097/00132586-198206000-00048 · Cited by 100
Lin, E. P., Soriano, S. G., & Loepke, A. W. (2013) · Anesthesiology Clinics · doi:10.1016/j.anclin.2013.10.003 · Cited by 99
Prospective randomized trial of ketorolac after congenital heart surgery
Gupta, A., Daggett, C. W., Drant, S. E., et al. (2004) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2004.05.024 · Cited by 94
Association of Preoperative Anemia With Postoperative Mortality in Neonates
Goobie, S. M., Faraoni, D., Zurakowski, D., et al. (2016) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2016.1032 · Cited by 94
de Ferranti, S. D., Gauvreau, K., Hickey, P. R., Jonas, R. A., Wypij, D., du Plessis, A., Bellinger, D. C., Kuban, K., Newburger, J. W., & Laussen, P. C. (2004) · Anesthesiology · doi:10.1097/00000542-200406000-00005 · Cited by 92
Anemia and transfusion in the neonate
Colombatti, R., Sainati, L., & Trevisanuto, D. (2015) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2015.12.001 · Cited by 87
Letal, M., & Theam, M. (2016) · BJA Education · doi:10.1093/bjaed/mkw047 · Cited by 86
Cerebral blood flow in the neonate
Vutskits, L. (2013) · Pediatric Anesthesia · doi:10.1111/pan.12307 · Cited by 78
Permissive hypercapnia to decrease lung injury in ventilated preterm neonates
Thome, U. H., & Ambalavanan, N. (2008) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2008.08.005 · Cited by 78
Smith's Anesthesia for Infants and Children
(2017) · Elsevier eBooks · doi:10.1016/c2013-0-15279-8 · Cited by 76
Definition of hypotension and assessment of hemodynamics in the preterm neonate
Cayabyab, R. G., McLean, C. W., & Seri, I. (2009) · Journal of Perinatology · doi:10.1038/jp.2009.29 · Cited by 73
Olbrecht, V. A., Skowno, J., Marchesini, V., Ding, L., Jiang, Y., Ward, C. G., Yu, G., Liu, H., Schurink, B., Vutskits, L., et al. (2017) · Anesthesiology · doi:10.1097/aln.0000000000001920 · Cited by 72
Walkden, G. J., Pickering, A. E., & Gill, H. (2019) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000004052 · Cited by 70
The conundrum of neonatal coagulopathy
Revel‐Vilk, S. (2012) · Hematology · doi:10.1182/asheducation.v2012.1.450.3798660 · Cited by 65
Safety of ketorolac in surgical neonates and infants 0 to 3 months old
Aldrink, J. H., Ma, M., Wang, W., et al. (2011) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2011.03.031 · Cited by 60
Nasr, V. G., Staffa, S. J., Zurakowski, D., et al. (2019) · Anesthesiology · doi:10.1097/aln.0000000000002659 · Cited by 60
Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates
Ardell, S. K., Offringa, M., Ovelman, C., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008342.pub2 · Cited by 57
Weinberg, A. C., Huang, L., Jiang, H. H., et al. (2011) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2011.02.006 · Cited by 55
Age and size are the major covariates for prediction of levobupivacaine clearance in children
CHALKIADIS, G. A., & Anderson, B. J. (2006) · Pediatric Anesthesia · doi:10.1111/j.1460-9592.2005.01778.x · Cited by 48
The conundrum of neonatal coagulopathy.
Revel‐Vilk, S. (2012) · PubMed · doi:10.1182/asheducation-2012.1.450 · Cited by 46
Anaesthetic considerations for surgery in newborns
Houck, C. S., & Vinson, A. E. (2017) · Archives of Disease in Childhood - Fetal and Neonatal Edition · doi:10.1136/archdischild-2016-311800 · Cited by 46
Cuffed endotracheal tubes in infants less than 3 kg: A retrospective cohort study
Thomas, R. E., Rao, S. C., Minutillo, C., et al. (2018) · Pediatric Anesthesia · doi:10.1111/pan.13311 · Cited by 44
Risk associated with anesthesia for noncardiac surgery in children with congenital heart disease
Taylor, D., & Habre, W. (2019) · Pediatric Anesthesia · doi:10.1111/pan.13595 · Cited by 41
Shan, Y., Yang, F., Tang, Z., Bi, C., Sun, S., Zhang, Y., & Liu, H. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00964 · Cited by 39
Nkilly, G. E., Michelet, D., Hilly, J., et al. (2013) · British Journal of Anaesthesia · doi:10.1093/bja/aet374 · Cited by 38
Perioperative events in children with pulmonary hypertension undergoing non‐cardiac procedures
Bernier, M. L., Jacob, A. I., Collaco, J. M., et al. (2017) · Pulmonary Circulation · doi:10.1177/2045893217738143 · Cited by 38
Calder, A., Bell, G., Andersson, M., et al. (2011) · Pediatric Anesthesia · doi:10.1111/j.1460-9592.2011.03771.x · Cited by 34
Hodes, H. L., Moloshok, R. E., & Markowitz, M. (1952) · PEDIATRICS · doi:10.1542/peds.10.2.138 · Cited by 32
The pharmacology of anaesthetics in the neonate
Anderson, B. J., & Allegaert, K. (2010) · Best practice & research. Clinical anaesthesiology · doi:10.1016/j.bpa.2010.02.019 · Cited by 32
Risk Adjustment for Neonatal Surgery: A Method for Comparison of In-Hospital Mortality
Lillehei, C. W., Gauvreau, K., & Jenkins, K. J. (2012) · PEDIATRICS · doi:10.1542/peds.2011-3647 · Cited by 28
Michelet, D., Brasher, C., Kaddour, H. B., et al. (2016) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2016.05.012 · Cited by 28
Blood Bupivacaine Concentrations After Transversus Abdominis Plane Block in Neonates
Suresh, S., & Oliveira, G. S. D. (2015) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000001088 · Cited by 24
Latham, H. E., Rawson, S. T., Dwyer, T. T., et al. (2012) · Journal of Clinical Monitoring and Computing · doi:10.1007/s10877-012-9337-1 · Cited by 22
Langley, R. J., McFadzean, J., & McCormack, J. G. (2015) · Pediatric Anesthesia · doi:10.1111/pan.12789 · Cited by 21
Glucose for children during surgery: Pros, cons, and protocols: A postgraduate educational review
Datta, P. K., & Aravindan, A. (2017) · Anesthesia Essays and Researches · doi:10.4103/aer.aer_39_17 · Cited by 20
Neuromuscular blocking drugs in infants and children
MEAKIN, G. (2007) · Continuing Education in Anaesthesia Critical Care & Pain · doi:10.1093/bjaceaccp/mkm032 · Cited by 19
Tracheal Length of Infants under Three Months Old
Lee, K., & Yang, C. (2001) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348940111000312 · Cited by 16
The cutting edge of neonatal anesthesia: the tide of history is changing
Kuratani, N. (2014) · Journal of Anesthesia · doi:10.1007/s00540-014-1817-7 · Cited by 13
Thomas, J., Weiß, M., Cannizzaro, V., et al. (2018) · Pediatric Anesthesia · doi:10.1111/pan.13430 · Cited by 13
Special considerations in the premature and ex-premature infant
Bayley, G. (2011) · Anaesthesia & intensive care medicine · doi:10.1016/j.mpaic.2010.11.007 · Cited by 11
Wagner, K. M., Raskin, J. S., Carling, N. P., et al. (2017) · World Neurosurgery · doi:10.1016/j.wneu.2017.10.149 · Cited by 9
Neuromuscular blocking drugs in infants and children
MEAKIN, G. (2008) · Continuing Education in Anaesthesia Critical Care & Pain · doi:10.1093/bjaceaccp/mkn009 · Cited by 8
Peripheral venous pressure predicts central venous pressure poorly in pediatric patients
Leipoldt, C. C. P., McKay, W. P. S., Clunie, M., & Miller, G. G. (2006) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/bf03021582 · Cited by 6
How Long Does Incisional Pain Last
Ririe, D. G. (2015) · Anesthesiology · doi:10.1097/aln.0000000000000660 · Cited by 5
Special considerations in the premature and ex-premature infant
Bayley, G. (2014) · Anaesthesia & intensive care medicine · doi:10.1016/j.mpaic.2014.01.001 · Cited by 4
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Research works printed but not linked: 1
- Tobias, 2016, Codeine: time to say "no." Section on anesthesiology and pain medicine, committee on drugs, Pediatrics, 10, 138
Cited by
Sorted by citations
Wang, Y., Wu, G., Song, J., Song, H., & Chu, Q. (2025) · Frontiers in Pediatrics · doi:10.3389/fped.2025.1567386 · Cited by 8
Metadata
- Authors
- Kuan, C. C., & Shaw, S. J.
- Affiliations
- Stanford Medicine (US)
- Corresponding author
- Kuan, Calvin C.
- ORCID
- Shaw, Susanna J.
- Venue
- Anesthesiology Clinics
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 38
- Issue
- 1
- Pages
- 1-18
- ISSN
- 1932-2275 (ISSN-L)
- OpenAlex
- W3004162045
- Cited by
- 26
- References
- 70
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 6 · 2023: 7 · 2022: 2 · 2021: 3 · 2020: 1
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Anesthesiology Clinics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac, Anesthesia and Surgical Outcomes
- Keywords
- neonatal anesthesia, perioperative risk, preterm infants, congenital heart disease, pulmonary hypertension, regional anesthesia, postoperative apnea, neonatal physiology, postoperative observation
- MeSH terms
- Anesthesia, Heart Arrest, Humans, Hypertension, Pulmonary, Infant, Newborn, Infant, Premature, Lung, Postoperative Complications, Respiration, Artificial, Surgical Procedures, Operative
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