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State-of-the-art review of advanced electrospun nanofiber yarn-based textiles for biomedical applications
Open accessAbstract
The pandemic of the coronavirus disease 2019 (COVID-19) has made biotextiles, including face masks and protective clothing, quite familiar in our daily lives. Biotextiles are one broad category of textile products that are beyond our imagination. Currently, biotextiles have been routinely utilized in various biomedical fields, like daily protection, wound healing, tissue regeneration, drug delivery, and sensing, to improve the health and medical conditions of individuals. However, these biotextiles are commonly manufactured with fibers with diameters on the micrometer scale (> 10 μm). Recently, nanofibrous materials have aroused extensive attention in the fields of fiber science and textile engineering because the fibers with nanoscale diameters exhibited obviously superior performances, such as size and surface/interface effects as well as optical, electrical, mechanical, and biological properties, compared to microfibers. A combination of innovative electrospinning techniques and traditional textile-forming strategies opens a new window for the generation of nanofibrous biotextiles to renew and update traditional microfibrous biotextiles. In the last two decades, the conventional electrospinning device has been widely modified to generate nanofiber yarns (NYs) with the fiber diameters less than 1000 nm. The electrospun NYs can be further employed as the primary processing unit for manufacturing a new generation of nano-textiles using various textile-forming strategies. In this review, starting from the basic information of conventional electrospinning techniques, we summarize the innovative electrospinning strategies for NY fabrication and critically discuss their advantages and limitations. This review further covers the progress in the construction of electrospun NY-based nanotextiles and their recent applications in biomedical fields, mainly including surgical sutures, various scaffolds and implants for tissue engineering, smart wearable bioelectronics, and their current and potential applications in the COVID-19 pandemic. At the end, this review highlights and identifies the future needs and opportunities of electrospun NYs and NY-based nanotextiles for clinical use.
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“Advances in polymer science have allowed precise control of the monomer and molecular weight ratios during PLCL synthesis, enabling customization of its degradation rate, mechanical strength, and cellular interactions to meet specific biomedical needs [9, 10].”
From Application of PLCL as a biodegradable polymer in biomedical engineering (2026) · cites this paper as [10]
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Metadata
- Authors
- Wu, S., Dong, T., Li, Y., Sun, M., Qi, Y., Liu, J., Kuss, M. A., Chen, S., & Duan, B.
- Affiliations
- Qingdao University (CN)
- University of Nebraska Medical Center (US)
- Corresponding author
- Wu, Shaohua
- Duan, Bin
- Venue
- Applied Materials Today
- Publisher
- Elsevier BV
- Published
- 2022-06
- Volume
- 27
- Pages
- 101473
- ISSN
- 2352-9407 (ISSN-L)
- PMC
- PMC8994858
- OpenAlex
- W4223548181
- Cited by
- 250
- References
- 239
- Citations by year
- 2026: 30 · 2025: 52 · 2024: 76 · 2023: 63 · 2022: 29
- FWCI
- 3.79
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Applied Materials Today (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Qingdao University
- Topics
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Physical Sciences › Materials Science › Biomaterials › Silk-based biomaterials and applications
- Physical Sciences › Materials Science › Polymers and Plastics › Textile materials and evaluations
- Keywords
- biotextiles, surgical sutures, tissue engineering scaffolds, implants, wearable bioelectronics, drug delivery, wound healing, face masks, smart textiles
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