Tau protein kinases: Involvement in Alzheimer's disease

Martin, Ludovic, Latypova, Xenia, Wilson, Cornelia M., Magnaudeix, Amandine, Perrin, Marie-Laure, Yardin, Catherine, Terro, Faraj·2013·Ageing Research Reviews

DOI 10.1016/j.arr.2012.06.003

Cited by (646)

Items 401–500 of 646

Targeting Glucocorticoid Receptors: A New Avenue for Alzheimer’s Disease Therapy
Geoffrey Canet, Nathalie Chevallier, Véronique Perrier, Catherine M. Desrumaux, Laurent Givalois · 2018 · Springer eBooks
Phosphorylation-driven aggregative proteins in neurodegenerative diseases: implications and therapeutics
Alba Espargaró, Raimon Sabaté · 2023 · Neural Regeneration Research
C-Reactive Protein Induces Tau Hyperphosphorylation via GSK3β Signaling Pathway in SH-SY5Y Cells
Haibiao Guo, Haitao Wang, Canmao Wang, Yufang Cheng, Zhengqiang Zou, Yiwen Li, Jingang Wu, Jiangping Xu · 2015 · Journal of Molecular Neuroscience
Insulin signaling as a therapeutic target in Alzheimer’s disease: Efficacy of apomorphine
Yasumasa Ohyagi, Satoko Takei · 2020 · Neurology and Clinical Neuroscience
Germacrone alleviates okadaic acid-induced neurotoxicity in PC12 cells via M1 muscarinic receptor-mediated Galphaq (Gq)/phospholipase C beta (PLCβ)/ protein kinase C (PKC) signaling
Mingqin Lin, Peiqiong Li, Wei Liu, Tianqi Niu, Liping Huang · 2022 · Bioengineered
Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models
Masoume Alipour, Majid Tebianian, Nahid Tofigh, Reyhaneh Sadat Taheri, Sayed Alireza Mousavi, Asal Naseri, Amin Ahmadi, Nayla Munawar, Koorosh Shahpasand · 2022 · Neuropeptides
Integrative computational evaluation of genetic markers for Alzheimer’s disease
Zhe Li, Zhenzhen Xiong, Lydia C. Manor, Hongbao Cao, Tao Li · 2018 · Saudi Journal of Biological Sciences
MiR-219 deficiency in Alzheimer’s disease contributes to neurodegeneration and memory dysfunction through post-transcriptional regulation of tau-kinase network
Mercedes Arnés, Yoon A. Kim, Jérôme Lannes, Maria Eugenia Alaniz, Joshua D. Cho, Brian D. McCabe, Ismael Santa‐María · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein
Mohammed M. Alhadidy, Nicholas M. Kanaan · 2024 · Biochemical Society Transactions
Evolving significance of kinase inhibitors in the management of Alzheimer's disease
Md Mustafiz Ansari, Sanjeev Kumar Sahu, Thakur Gurjeet Singh, Sovia R.J. Singh, Paranjeet Kaur · 2024 · European Journal of Pharmacology
Protein kinases as therapeutic targets for Alzheimer’s disease: a brief review
Isabela Marie Fernandes Silva, Graziella dos Reis Rosa Franco, Vanessa Silva Gontijo, Cláudio Viegas · 2024 · Exploration of Neuroprotective Therapy
Multifactorial etiology of progressive supranuclear palsy (PSP): the genetic component
Ulrich Müller, Günter U. Höglinger, Dennis W. Dickson · 2025 · Acta Neuropathologica
Electroanalytical Sensors and Methods for Assays and Studies of Neurological Biomarkers
Shu Chen, Lin Zhang, Yunfei Long, Feimeng Zhou · 2014 · Electroanalysis
Beyond Amyloid: A Machine Learning-Driven Approach Reveals Properties of Potent GSK-3β Inhibitors Targeting Neurofibrillary Tangles
Martin C. Nwadiugwu, Ikenna Obinwanne Onwuekwe, Echezona Edozie Ezeanolue, Hong‐Wen Deng · 2024 · International Journal of Molecular Sciences
Derailed Intraneuronal Signalling Drives Pathogenesis in Sporadic and Familial Alzheimer’s Disease
Tom Van Dooren, Katrien Princen, Koen De Witte, Gerard Griffioen · 2014 · BioMed Research International
Deposition of Phosphorylated α-Synuclein and Activation of GSK-3β and PP2A in the PS19 Mouse Model of Tauopathy
Yuta Takaichi, James Kenn CHAMBERS, Yasuhisa Ano, Akihiko Takashima, Hiroyuki Nakayama, Kazuyuki Uchida · 2021 · Journal of Neuropathology & Experimental Neurology
Combination of Alpinia Oxyphylla Fructus and Schisandra Chinensis Fructus ameliorates aluminum-induced Alzheimer's disease via reducing BACE1 expression
Mengshi Wang, Fei Lin, Xiaoying Zhang, Ming Zhang, Tingxu Yan, Bo Ming Wu, Yiyang Du, Bosai He, Ying Jia · 2022 · Journal of Chemical Neuroanatomy
Monitoring Protein Kinase Expression and Phosphorylation in Cell Lysates with Antibody Microarrays
Hong Zhang, Xiaoqing Shi, Steven Pelech · 2015 · Methods in molecular biology
(Z)‐2‐(3‐Chlorobenzylidene)‐3,4‐dihydro‐N‐(2‐methoxyethyl)‐3‐oxo‐2H‐benzo[b][1,4]oxazine‐6‐carboxamide as GSK ‐3β inhibitor: Identification by virtual screening and its validation in enzyme‐ and cell‐based assay
Prashant Joshi, Mehak Gupta, Ram Ashrey Vishwakarma, Ajay Kumar, Sandip Bibishan Bharate · 2016 · Chemical Biology & Drug Design
Kinase-loaded magnetic beads for sequential in vitro phosphorylation of peptides and proteins
Lenka Hromádková, Rudolf Kupčík, Marie Vajrychová, P. Přikryl, Andrea Charvátová, Barbora Jankovičová, Daniela Řı́pová, Zuzana Bı́lková, Marcela Slováková · 2017 · The Analyst
Diverse influences on tau aggregation and implications for disease progression
Meaghan Van Alstyne, James Pratt, Roy Parker · 2025 · Genes & Development
P25/CDK5-mediated Tau Hyperphosphorylation in Both Ipsilateral and Contralateral Cerebra Contributes to Cognitive Deficits in Post-stroke Mice
Jing Hua Yu, Yang Zhao, Xiaokang Gong, Zheng Liang, Yanna Zhao, Xin Li, Yu‐Ju Chen, Youhua Yang, Mengjuan Wu, Xiaochuan Wang et al. · 2023 · Current Medical Science
Crocin has a greater therapeutic role in the restoration of behavioral impairments caused by maternal social isolation in adolescent than in adult offspring probably through GSK-3beta downregulation
Hanie Karimi, Marjan Mohamadian, Paniz Azizi, Pouya Ghasemi, Mokhtar Karimi, Tannaz Layegh, Majid Rahmatkhah-Yazdi, Salar Vaseghi · 2024 · Learning and Motivation
Review on pathogenesis and treatment of Alzheimer's disease
Jinxia Cai, Yanqing Liu, Haojun Fan · 2024 · Developmental Dynamics
Brain phosphoproteomic analysis identifies diabetes‐related substrates in Alzheimer's disease pathology in older adults
Ana Werneck Capuano, Vishal Sarsani, Shinya Tasaki, Rupal I. Mehta, Jun Li, Rexford S. Ahima, Steven Edward Arnold, David Alan Bennett, Vladislav Petyuk, Liming Liang et al. · 2024 · Alzheimer s & Dementia
Identification of a novel pyrrolo[2,3- b ]pyridine compound as a potent glycogen synthase kinase 3β inhibitor for treating Alzheimer’s disease
Qingqing Xun, Jing Zhang, Lei Feng, Yuying Ma, Ying Li, Xiaolong Shi · 2025 · Journal of Enzyme Inhibition and Medicinal Chemistry
Improving vulnerable Calbindin1− neurons in the ventral hippocampus rescues tau-induced impairment of episodic memory
Huiyang Lei, Jingru Lv, Fuqiang Zhang, Linyu Wei, Kun Shi, Jiale Liu, Ting He, Rui Xiong, Fei Sun, Tongkai Zhong et al. · 2025 · Translational Neurodegeneration
The 28-day repeated arsenic exposure increases tau phosphorylation in the rat brain
Churaibhon Wisessaowapak, Luksamee Worasuttayangkurn, Kanjanamas Maliphol, Watanyoo Nakareangrit, Wanida Cholpraipimolrat, Sumontha Nookabkaew, Piyajit Watcharasit, Jutamaad Satayavivad · 2022 · Environmental Toxicology and Pharmacology
Multi-Target-Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery
Vaishali Manikrao Patil, Neeraj Masand, Vertika Gautam, Shikha Kaushik, Dee H. Wu · 2023 · Springer eBooks
Radiosynthesis and evaluation of a novel 18F-labeled tracer for PET imaging of glycogen synthase kinase 3
Zhiwei Xiao · 2024 · American Journal of Nuclear Medicine and Molecular Imaging
Melatonin Supplementation in Alzheimer’s disease: The Potential Role in Neurogenesis
Rasoul Ebrahimi, Ali Faramarzi, Shakiba Salarvandian, Reyhaneh Zarei, M. Heidari, Fatemeh Salehian, K. Esmaeilpour · 2025 · Molecular Neurobiology
Development of Kinase Inhibitors via Metal-Catalyzed C–H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies
Florence Couly, Marine Harari, Carole Dubouilh‐Benard, Laëtitia Bailly, Émilie Petit, Julien Diharce, Pascal Bonnet, Laurent Meijer, Corinne Fruit, Thierry Besson · 2018 · Molecules
Synthesis and in vitro evaluation of diverse heterocyclic diphenolic compounds as inhibitors of DYRK1A
Qingqing Zhou, Tristan A. Reekie, Ramzi H. Abbassi, Dinesh C. Indurthi, Josep S. Font, Renae M. Ryan, Lenka Munoz, Michael Kassiou · 2018 · Bioorganic & Medicinal Chemistry
Polyphenol-Peptide Interactions in Mitigation of Alzheimer’s Disease: Role of Biosurface-Induced Aggregation
Roger Gaudreault, Vincent Hervé, Theo G. M. van de Ven, Normand Mousseau, Charles Ramassamy · 2021 · Journal of Alzheimer s Disease
Effects of Specific Inhibitors for CaMK1D on a Primary Neuron Model for Alzheimer’s Disease
Paige Grant, Jitendra Kumar, Satyabrata Kar, Michael Overduin · 2021 · Molecules
Tau and stathmin proteins in breast cancer: A potential therapeutic target
Hanzhao Yang · 2022 · Clinical and Experimental Pharmacology and Physiology
Tauopathies: The Role of Tau in Cellular Crosstalk and Synaptic Dysfunctions
Marta Caamaño-Moreno, Ricardo Gargini · 2022 · Neuroscience
Cognitive dysfunction and increased phosphorylated tau are associated with reduced O‐GlcNAc signaling in an aging mouse model of metabolic syndrome
Shreya Gupta, Sanjay K.A. Jinka, Saugat Khanal, Neha Bhavnani, Fayez Almashhori, Jason Lallo, Amy Mathias, Yasmine Al‐Rhayyel, Danielle E. Herman, John G. Holden et al. · 2023 · Journal of Neuroscience Research
Glycogen Synthase Kinase-3β, NLRP3 Inflammasome, and Alzheimer’s Disease
Yue-ran Jia, Zi-qing Guo, Qian Guo, Xiaochuan Wang · 2023 · Current Medical Science
Deep Phosphoproteomic Measurements Pinpointing Drug Induced Protective Mechanisms in Neuronal Cells
Chengli Yu, Jing Gao, Yanting Zhou, Xiangling Chen, Ruoxuan Xiao, Jing Zheng, Yansheng Liu, Hu Zhou · 2016 · Frontiers in Physiology
Industrial medicinal chemistry insights: neuroscience hit generation at Janssen
Gary Tresadern, Frederik J. R. Rombouts, Daniel Oehlrich, Gregor J. Macdonald, Andrés A. Trabanco · 2017 · Drug Discovery Today
Unravelling the Selectivity of 6,7‐Dimethyl Quinoxaline Analogs for Kinase Inhibition: An Insight towards the Development of Alzheimer's Therapeutics
Arvind Kumar Jain, Arindam Gupta, Chandrabose Karthikeyan, Piyush Trivedi, Anita Dutt Konar · 2021 · Chemistry & Biodiversity
Casein Kinase 1δ Phosphorylates TDP-43 and Suppresses Its Function in Tau mRNA Processing
Mingming Yang, Rongrong Qi, Yuxiao Liu, Xin Shen, Yulou Zhao, Nana Jin, Ruozhen Wu, Fei Liu, Jianlan Gu · 2023 · Journal of Alzheimer s Disease
Advancing Alzheimer's disease pharmacotherapy: efficacy of glucocorticoid modulation with dazucorilant (CORT113176) in preclinical mouse models
Geoffrey Canet, Charleine Zussy, Mathieu Vitalis, Françoise Morin, Nathalie Chevallier, Hazel Hunt, Sylvie Claeysen, Marine Blaquière, Nicola Marchi, Emmanuel Planel et al. · 2025 · British Journal of Pharmacology
Role of saturated fatty acid metabolism in posttranslational modifications of the Tau protein
Valeria Melissa García-Cruz, Roberto Coria, Clorinda Arias · 2025 · Molecular and Cellular Biochemistry
Tau and tauopathies across primate species: implications for modeling neurodegenerative disorders
Julia C. Colwell, Marina Elena Emborg · 2025 · Frontiers in Aging Neuroscience
Pathological Calcium Signaling in Traumatic Brain Injury and Alzheimer’s Disease: From Acute Neuronal Injury to Chronic Neurodegeneration
Stephan Neuschmid, Carla Schallerer, Barbara E. Ehrlich, Declan McGuone · 2025 · International Journal of Molecular Sciences
Tau post-translational modifications in Alzheimer's disease: Insights into pathogenesis, therapeutic strategies, and diagnostic advances
Hui Lei, Xiaohua Chen, Longzhu Ruan, Xuena Liu, Fei Ye, Kejing Li, Wei Cheng, Boyi Yu, Cuixia Di, Cuixia Di · 2025 · Ageing Research Reviews
Lactational exposure to perfluorooctane sulfonate remains a potential risk in brain function of middle-aged male mice
Ayane Ninomiya, Izuki Amano, Hiraku Suzuki, Yuki Fujiwara, Asahi Haijima, Noriyuki Koibuchi · 2024 · The Journal of Physiological Sciences
The glucocorticoid receptors regulation in Alzheimer's disease
Laurent Givalois · 2013 · Neurobiology of Aging
The Role of p53 in Alzheimer’s Disease: Impact on Tau Pathology
Maja Jazvinšćak Jembrek, Katy Newberg, Goran Šimić · 2018 · Springer eBooks
Association of Genes Involved in the Metabolic Pathways of Amyloid-β and Tau Proteins With Sporadic Late-Onset Alzheimer’s Disease in the Southern Han Chinese Population
Xuewen Xiao, Bin Jiao, Xinxin Liao, Weiwei Zhang, Zhenhua Yuan, Lina Guo, Xin Wang, Lu Zhou, Xixi Liu, Xinxiang Yan et al. · 2020 · Frontiers in Aging Neuroscience
Methyl donor supplementation reduces phospho‐Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy
Annika van Hummel, Goce Taleski, Jean‐Marie Sontag, Astrid Feiten, Yazi Diana Ke, Lars Matthias Ittner, Estelle Sontag · 2023 · Neuropathology and Applied Neurobiology
Preferential Selectivity of Inhibitors with Human Tau Protein Kinase Gsk3 Elucidates Their Potential Roles for Off-Target Alzheimer’s Therapy
Jagadeesh Kumar D, Holenarasipur GunduRao Nagendra · 2013 · International Journal of Alzheimer s Disease
The Kv7 channel opener Retigabine reduces neuropathology and alleviates behavioral deficits in APP/PS1 transgenic mice
Dongpei Zhuang, Nan yu, Han Shuo, Xinyao Zhang, Chuanxia Ju · 2024 · Behavioural Brain Research
MicroRNA-219 in the central nervous system: a potential theranostic approach
Nahal Shamaeizadeh, Mina Mirian · 2024 · Research in Pharmaceutical Sciences
Deciphering T Cell Dynamics in Alzheimer's Disease Pathogenesis: Insights and Implications
Qiqi Yang, Yunjie Qiu, Junjun Ni, Hui Li, Hong Qing · 2025 · Current Neuropharmacology
Phenolic compounds as anti-Alzheimer’s disease agents
Jorge Medeiros · 2025 · Exploration of neuroscience
Biomarkers and Target-Specific Small-Molecule Drugs in Alzheimer’s Diagnostic and Therapeutic Research: From Amyloidosis to Tauopathy
Sheng Li, Rajiv Bhalla · 2024 · Neurochemical Research
Early intervention using long-term rhythmic pulsed magnetic stimulation alleviates cognitive decline in a 5xFAD mouse model of Alzheimer's disease
Xue Wang, Qingmeng Wang, Xuting Wang, Haoyu Zhao, Chuncheng Zhao, Yangkun Jiao, Hongkai Shi, Changyou Chen, Haitao Chen, Pingping Wang et al. · 2024 · Experimental Neurology
Molecular Motors in Myelination and Their Misregulation in Disease
Daniel José Barbosa, Cátia Carvalho, Inês D. Costa, Renata Silva · 2024 · Molecular Neurobiology
Hyperphosphorylated tau-based Alzheimer’s Disease drug discovery: Identification of inhibitors of tau aggregation and cytotoxicity
Hsiao‐Tien Chien Hagar, Virneliz Fernández-Vega, Kuang‐Wei Wang, Luis M. Ortiz Jordan, Justin Shumate, Louis D. Scampavia, April Sweet Tapayan, Hien M. Nguyen, Timothy Spicer, Min‐Hao Kuo · 2025 · SLAS DISCOVERY
Protein-protein interactions of cytochromes P450 3A4 and 3A5 with their intermediate redox partners cytochromes
Oksana V. Gnedenko, Alexis S. Ivanov, Evgeniy O. Yablokov, Sergey A. Usanov, Dzmitry Mukha, Г. В. Сергеев, Alexey V. Kuzikov, Tatiana V. Bulko, Natalia E. Moskaleva, Victoria V. Shumyantseva et al. · 2014 · Biomeditsinskaya Khimiya
Phosphorylation of Tau Protein by CDK2/cyclin A and GSK3β Recombinant Kinases: Analysis of Phosphorylation Patterns by Nuclear Magnetic Resonance Spectroscopy
Léa El Hajjar, Clarisse Bridot, Marine Nguyen, François‐Xavier Cantrelle, Isabelle Landrieu, Caroline Smet‐Nocca · 2024 · Methods in molecular biology
Anatabine Attenuates Tau Phosphorylation and Oligomerization in P301S Tau Transgenic Mice
Daniel Paris · 2014 · Brain Disorders & Therapy
Biological evaluation and energetic analyses of novel GSK‐3 β inhibitors
Denan Zhang, Lei Liu, Lin Pang, Qing Jin, Kehui Ke, Ming Hu, Jingbo Yang, Wei-fang Ma, Hongbo Xie, Xiujie Chen · 2017 · Journal of Cellular Biochemistry
Effect of Peripheral Insulin Administration on Phosphorylation of Tau in the Brain
Yanli Jiang, Longfei Li, Chun‐Ling Dai, Ranran Zhou, Cheng‐Xin Gong, Khalid Iqbal, Jin‐Hua Gu, Fei Liu · 2020 · Journal of Alzheimer s Disease
The Role of 18F-Flortaucipir (AV-1451) in the Diagnosis of Neurodegenerative Disorders
Saswata Roy, Dipanjan Banerjee, Indrajit Chatterjee, Deepika Natarajan, Christopher Joy Mathew · 2021 · Cureus
Design, synthesis and biological evaluation of naphthalene-pyrazoline derivatives as neuroprotective agents for alzheimer's disease
Anushka Sharma, Subhadip Maity, Shankar Gupta, Abuzer Ali, Amena Ali, Vivek Asati · 2025 · Journal of the Indian Chemical Society
ZIF-8 Microswimmers Self-Fast Dynamic Destruction in Microliter Volumes of Cerebrospinal Fluid Samples: Toward a Selective Assessment of Amyloidosis
Javier Bujalance‐Fernández, Eva Carro, Desireé Antequera, Beatriz Jurado‐Sánchez, Alberto Escarpa · 2025 · Analytical Chemistry
Recent Drugs Tested in Clinical Trials for Alzheimer´s and Parkinson´s Diseases Treatment: Current Approaches in Tracking New Drugs
Fernanda Majolo, LavyniaFerreira Hoffmann, Wilian Luan Pilatti Sant’Ana, Celso Alves, Joana Silva, Alice Martins, Rui Pedrosa, Bruno Rampanelli Dahmer, Guilherme Liberato da Silva, Luís Fernando Saraiva Macedo Timmers et al. · 2024 · Frontiers in clinical drug research. CNS and neurological disorders
Harnessing the potential of long non-coding RNAs in the pathophysiology of Alzheimer's disease
Rasanpreet Kaur, Swadha Pandey, Saurabh Kumar Gupta, Jitendra Pratap Singh · 2024 · Experimental Neurology
Occlusal disharmony transiently decrease cognition via cognitive suppressor molecules and partially restores cognitive ability via clearance molecules
Munehisa Maeshiba, Hiroshi Kajiya, Takashi Tsutsumi, Keisuke Migita, Kazuko Goto-T, Yuri Kono, Takashi Tsuzuki, Jun Ohno · 2022 · Biochemical and Biophysical Research Communications
Interdisciplinary Approaches to Deal with Alzheimer’s Disease—From Bench to Bedside: What Feasible Options Do Already Exist Today?
Irene Ablinger, Katharina Dressel, Thea Rott, Anna Andrea Lauer, Michael Tiemann, João Pedro Batista, Tim Taddey, Heike S. Grimm, Marcus O.W. Grimm · 2022 · Biomedicines
Beneficial Effects of Echinacoside on Cognitive Impairment and Diabetes in Type 2 Diabetic db/db Mice
Fanglin Qin, Yiming Yan, Ningxi Yang, Yarong Hao · 2024 · Experimental and Clinical Endocrinology & Diabetes
Crafting cationic lecithmer nanocomposites as promising wagons for brain targeting of cinnamaldehyde: Accentuated neuroprotection via downregulation of Aβ1-42/p-tau crosstalk
Amany A. Azouz, Mohammed H. Elkomy, Mohammed Elmowafy, Mohamed O. Mahmoud, Fares E.M. Ali, Heba M. Aboud · 2025 · Journal of Drug Delivery Science and Technology
From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein‐Templated Synthesis
Vanesa Nozal, Alfonso García‐Rubia, Eva P. Cuevas, Concepción Pérez, Carlota Tosat‐Bitrián, Fernando Benito Bartolomé, Eva Carro, David Ramírez, Valle Palomo, Ana Martı́nez · 2021 · Angewandte Chemie
Activation of Pro-survival CaMK4β/CREB and Pro-death MST1 signaling at early and late times during a mouse model of prion disease
Rory H Shott, Anna Majer, Kathy L. Frost, Stephanie A. Booth, Luis M. Schang · 2014 · Virology Journal
Small molecule-mediated therapeutic approaches to target Tau and Alzheimer’s disease
Subashchandrabose Chinnathambi · 2024 · Advances in protein chemistry and structural biology
Differential roles of human tau isoforms in the modulation of inflammation and development of neuropathology
Brian J. Spencer, Aaron Schueler, Daniel Sung, Robert A. Rissman · 2025 · Neurobiology of Disease
Tunable nanospanlastics for 18α-Glycyrrhetinic acid brain targeted delivery to manage cognitive deficits and misfolded protein aggregates in Alzheimer's disease: In vitro optimization and in vivo pharmacodynamics assessment
Hussein M. Eid, Mohammed H. Elkomy, Mohamed O. Mahmoud, Heba M. Aboud, Fares E.M. Ali, Ahmed.M.Abdelhaleem Ali, Amany A. Azouz · 2025 · Journal of Drug Delivery Science and Technology
Pathophysiological mechanism and natural preventive and therapeutic strategies of Alzheimer's disease
Abdelkader Basli, Jihane Bounaas · 2022 · Nutrition and Health
Application of computational methods in the drug discovery and development of Alzheimer's disease
Qianqian Zhang, Xiaoqing Gong, Huanxiang Liu, Xiaojun Yao · 2025 · Acta Pharmaceutica Sinica B
High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer's Disease Via a Specific Tau Phosphorylation Pattern
Yuki Ito, Shuko Takeda, Tsuneo Nakajima, A. Oyama, Haruo Takeshita, Kazumasa Miki, Yoichi Takami, Yasushi Takeya, Munehisa Shimamura, Hiromi Rakugi et al. · 2023 · The Journal of Prevention of Alzheimer s Disease
Upregulation of LRRK2 following traumatic brain injury does not directly phosphorylate Thr175 tau
Neil S. Donison, Matthew A Hintermayer, Maegha Subramaniam, Erin Santandrea, Kathryn Volkening, Michael Joseph Strong · 2023 · Frontiers in Cellular Neuroscience
In situ study of RSK2 kinase activity in a single living cell by combining single molecule spectroscopy with activity-based probes
Shengrong Yu, Zhixue Du, Chaoqing Dong, Jicun Ren · 2019 · The Analyst
Tauopathy
Hao Chi, Tzu‐Kang Sang, Hui-Yun Chang · 2019 · IntechOpen eBooks
Substituent Orchestration in Dimethylquinoxaline Derivatives: A Tool for Fishing Out Appropriate CDK5 Inhibitors as Potential Therapeutics for Alzheimer's
Arvind Kumar Jain, Arindam Gupta, Chandrabose Karthikeyan, Piyush Trivedi, Anita Dutt Konar · 2022 · Chemistry & Biodiversity
Identification of Novel Kinases of Tau Using Fluorescence Complementation Mass Spectrometry (FCMS)
Der‐Shyang Kao, Yanyan Du, Andrew G. DeMarco, Sehong Min, Mark C. Hall, Jean‐Christophe Rochet, W. Andy Tao · 2022 · Molecular & Cellular Proteomics
Molecular Aspects of a Diet as a New Pathway in the Prevention and Treatment of Alzheimer’s Disease
Julia Doroszkiewicz, Jan Mroczko, Piotr Rutkowski, Barbara Mroczko · 2023 · International Journal of Molecular Sciences
The Association Between Single Nucleotide Polymorphisms of GSK 3β Gene and Sporadic Alzheimer’s Disease in a Cohort of Southern Chinese Han Population
Jing Li, Fan Zeng, Juan Deng, Jie Zhu, Lin Li, Tao Zhang, Juan Liu, Li–Li Zhang, Chang‐Yue Gao, Meng Zhang et al. · 2014 · Neurotoxicity Research
Weak central coherence in patients with Alzheimer's disease(•).
Selina Mårdh · 2013 · PubMed Central
MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation
Andrew M. Haidle, Kaleen K. Childers, Anna A. Zabierek, Jason D. Katz, James P. Jewell, Yongquan Hou, Michael D. Altman, Alexander A. Szewczak, Dapeng Chen, Andreas Harsch et al. · 2016 · Bioorganic & Medicinal Chemistry Letters
Neuroimmune Dynamics in Alzheimer’s Disease Progression
Víctor Andrade, Leonardo Guzmán‐Martínez, Katiana Vergara-Pulgar, Ricardo Benjamin Maccioni · 2017 · InTech eBooks
Progression in Alzheimer’s Disease Correlates With Epigenetics and Cerebral Formaldehyde: From Potential Hereditary Mechanism and Environmental Factors to Therapeutic Measures
Mohit Pant, Siddhartha Dan, Sujata Pant, A. Nirmal Paul Raj, Sushil Kumar Upadhyay · 2021 · Current Pharmacology Reports
Targeted Drug Delivery: Amyloid Beta Targeting Drugs, Immunotherapy, Anti-Tau and Aggregation Inhibitor, Microtubule-Stabilizing, and Neuroinflammation Modulation
Pavan Kumar Chintamaneni, Sai Kiran S. S. Pindiprolu, Praveen Thaggikuppe Krishnamurthy, Magham Sai Varshini · 2024 · Springer eBooks
Contributions of major tau kinase activation and phospho-tau accumulation to cortical and hippocampal tangle formation and cognition in older adults
Elena Hernández‐Hernández, Vladislav Petyuk, Júlia Valor-Blanquer, Fernando Yáñez-Gómez, Alasdair M. Barr, Philip L. De Jager, Er‐Yun Chen, Sue E. Leurgans, Julie A. Schneider, David A. Bennett et al. · 2025 · Neurobiology of Disease
Biomolecular phase separation of microtubule-associated protein tau and its role in the genesis of brain disorders
Aurgha Kamal Bhandari, Aman Singh Dhami, Rishi Thanavanthan Hemanthlumar, Nishant Mishra, Beula Joslyn, Sindhujit Roy, Jaisri Srinivasan, Kailash Prasad Prajapati, Karunakar Kar, Bibin Gnanadhason Anand · 2025 · Ageing Research Reviews
Proteostasis disruption and lipid dyshomeostasis in neurodegeneration: exploring common druggable targets across sporadic and monogenic disorders
Priscila Pereira Sena, Lea Friedrich, Alcibiades E. Villarreal, Florian Fath, Liubovi Sopco, Mar Hernández‐Guillamón, Maria Luiza Saraiva Pereira, Gabrielle B. Britton, Jonasz Jeremiasz Weber, Thorsten Schmidt · 2025 · Frontiers in Molecular Neuroscience
Post-translational modifications as a regulatory code for tau function in health and disease
Abigail J. Nordbeck, Bhirisha Sharma, Charles A. Garcia, Jui‐Heng Tseng · 2026 · Frontiers in Dementia