Tau protein kinases: Involvement in Alzheimer's disease
Martin, Ludovic, Latypova, Xenia, Wilson, Cornelia M., Magnaudeix, Amandine, Perrin, Marie-Laure, Yardin, Catherine, Terro, Faraj·2013·Ageing Research Reviews
Cited by (646)
Items 201–300 of 646
- Perindopril ameliorates experimental Alzheimer’s disease progression: role of amyloid β degradation, central estrogen receptor and hyperlipidemic-lipid raft signalingBasim Anwar Shehata Messiha, Mohammed R.A. Ali, Mahmoud Mohamed Khattab, Amira M. Abo‐Youssef · 2020 · Inflammopharmacology
- Role of the endolysosomal pathway and exosome release in tau propagationYan, Minli, Zheng, Tingting · 2021 · Neurochemistry International
- Genome-wide association study and functional validation implicates JADE1 in tauopathyKurt W. Farrell, SoongHo Kim, Natalia Han, Megan A. Iida, Elias M. Gonzalez, Marcos Otero‐García, Jamie M. Walker, Timothy E. Richardson, Alan Edward Renton, Shea J. Andrews et al. · 2021 · Acta Neuropathologica
- Unveiling the therapeutic potential of natural products in Alzheimer’s disease: insights from in vitro, in vivo, and clinical studiesNahida Aktary, Yerim Jeong, Seungji Oh, Yeju Shin, Yoonsoo Sung, Muntajin Rahman, Lívia Ramos Santiago, Jinwon Choi, Han Gyeul Song, Fahrul Nurkolis et al. · 2025 · Frontiers in Pharmacology
- 2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; A new class of potent, selective and orally active glycogen synthase kinase-3β inhibitorsKenji Fukunaga, Fumiaki Uehara, Keiichi Aritomo, Aya Shoda, Shinsuke Hiki, Masahiro Okuyama, Yoshihiro Usui, Kazutoshi Watanabe, Koichi Yamakoshi, Toshiyuki Kohara et al. · 2013 · Bioorganic & Medicinal Chemistry Letters
- Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative DiseasesAndrea I. Krahn, Carrow I. Wells, David H. Drewry, Lenore K. Beitel, Thomas M. Durcan, Alison D. Axtman · 2020 · ACS Chemical Neuroscience
- TBK1 interacts with tau and enhances neurodegeneration in tauopathyMeasho H. Abreha, Shamsideen A. Ojelade, Eric B. Dammer, Zachary T. McEachin, Duc Minh Duong, Marla Gearing, Gary Jonathan Bassell, James J. Lah, Allan I. Levey, Joshua M Shulman et al. · 2021 · Journal of Biological Chemistry
- Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodentMiranda E. Orr, Valentina Rose Garbarino, Angelica Salinas, Rochelle Buffenstein · 2014 · Neurobiology of Aging
- Non-Phosphorylated Tau as a Potential Biomarker of Alzheimer’s Disease: Analytical and Diagnostic CharacterizationPiotr Lewczuk, Natalia Lelental, Ingolf Lachmann, Max Holzer, Katharina Flach, Sebastian Brandner, Sebastiaan Engelborghs, Charlotte Elisabeth Teunissen, Henrik Zetterberg, José Luís Molinuevo et al. · 2016 · Journal of Alzheimer s Disease
- Revolutionizing Alzheimer's treatment: Harnessing human serum albumin for targeted drug delivery and therapy advancementsDivya Shastri, Vinit Raj, Sang-Kil Lee · 2024 · Ageing Research Reviews
- The Streptomyces metabolite anhydroexfoliamycin ameliorates hallmarks of Alzheimer’s disease in vitro and in vivoMarta Leirós, Eva Alonso, Mostafa Ezzat Rateb, Rainer Ebel, Marcel Jaspars, Amparo Alfonso, Luis Miguel Botana · 2015 · Neuroscience
- The Goldilocks paradigm: comparing classical machine learning, large language models, and few-shot learning for drug discovery applicationsScott H. Snyder, Patricia A. Vignaux, Mustafa Kemal Ozalp, Jacob Gerlach, Ana C. Puhl, Thomas R. Lane, John Corbett, Fabio Urbina, Sean Ekins · 2024 · Communications Chemistry
- Molecular Mechanisms of Alzheimer’s Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for Neuronal TherapyEun Hee Ahn, Jae‐Bong Park · 2025 · Cells
- First Selective Dual Inhibitors of Tau Phosphorylation and Beta-Amyloid Aggregation, Two Major Pathogenic Mechanisms in Alzheimer’s DiseaseMarica Mariano, Christian Schmitt, Parisa Miralinaghi, Marco Catto, Rolf W. Hartmann, Angelo Carotti, Matthias Engel · 2014 · ACS Chemical Neuroscience
- Knockdown of microRNA-195 contributes to protein phosphatase-2A inactivation in rats with chronic brain hypoperfusionChengdi Liu, Qin Wang, De‐Kang Zong, Shuang‐Chao Pei, Yan Yan, Meiling Yan, Linlin Sun, Yang-Yang Hao, Meng Mao, Wenjing Xing et al. · 2016 · Neurobiology of Aging
- Common mechanisms underlying axonal transport deficits in neurodegenerative diseases: a mini reviewXiaoman Yang, Zhuoran Ma, Piaopiao Lian, Yan Chun Xu, Xuebing Cao · 2023 · Frontiers in Molecular Neuroscience
- Discovery of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally-active GSK-3β inhibitors for Alzheimer’s diseaseKenji Fukunaga, Daiki Sakai, Kazutoshi Watanabe, Kazuki Nakayama, Toshiyuki Kohara, Hiroshi Tanaka, Shinji Sunada, Mika Nabeno, Masako Okamoto, Ken-Ichi Saito et al. · 2015 · Bioorganic & Medicinal Chemistry Letters
- Identifying GSK-3β kinase inhibitors of Alzheimer's disease: Virtual screening, enzyme, and cell assaysChih‐Hsin Lin, Yu-Shao Hsieh, Yih‐Ru Wu, Chia-Jen Hsu, Hsuan-Chiang Chen, Wun‐Han Huang, Kuo‐Hsuan Chang, Hsiu Mei Hsieh‐Li, Ming‐Tsan Su, Ying‐Chieh Sun et al. · 2016 · European Journal of Pharmaceutical Sciences
- Potential of Medicinal Plants as Neuroprotective and Therapeutic Properties Against Amyloid-β-Related Toxicity, and Glutamate-Induced Excitotoxicity in Human Neural CellsLobine, Devina, Sadeer, Nabeelah, Jugreet, Sharmeen, Suroowan, Shanoo, Keenoo, Bibi Sumera, Imran, Muhammad, Venugopala, Katharigatta N., Ibrahim, Faten Mohamed, Zengin, Gokhan, Mahomoodally, Mohamad Fawzi · 2021 · Current Neuropharmacology
- Synthesis of pyrimidin-4-one-1,2,3-triazole conjugates as glycogen synthase kinase-3β inhibitors with anti-depressant activityImran Khan, Mushtaq A. Tantray, Hinna Hamid, Mohammad Sarwar Alam, Abul Kalam, Firasat Hussain, Abhijeet Dhulap · 2016 · Bioorganic Chemistry
- Administration of Momordica charantia Enhances the Neuroprotection and Reduces the Side Effects of LiCl in the Treatment of Alzheimer’s DiseaseHei-Jen Huang, Shu-Ling Chen, Yen-Ting Chang, Jong‐Ho Chyuan, Hsiu Mei Hsieh‐Li · 2018 · Nutrients
- G protein‐coupled receptor kinases are associated with Alzheimer's disease pathologyThais Rafael Guimarães, Eric Swanson, Julia Kofler, Amantha Thathiah · 2021 · Neuropathology and Applied Neurobiology
- Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in miceTorben Johann Hausrat, Philipp Christoph Janiesch, Petra Breiden, David Lutz, Sabine Hoffmeister‐Ullerich, Irm Hermans‐Borgmeyer, Antonio Virgilio Failla, Matthias Kneussel · 2022 · Nature Communications
- DYRK1A Inhibitors and Perspectives for the Treatment of Alzheimer's DiseaseMárcia María de Souza, Arthur Ribeiro Cenci, Kerolain Faoro Teixeira, Valkiria Machado, Majory C.G.M. Schülerb, Ana Elisa Gonçalves, Ana Paula Dalmagro, Camila André Cazarin, Leonardo L. G. Ferreira, Aldo Sena de Oliveira et al. · 2022 · Current Medicinal Chemistry
- Role of astrocytes in sleep deprivation: accomplices, resisters, or bystanders?Mengxin Que, Yujuan Li, Xuan Wang, Gaofeng Zhan, Xiaoxiao Luo, Zhiqiang Zhou · 2023 · Frontiers in Cellular Neuroscience
- Terpenes as Potential Anti-Alzheimer’s Disease AgentsElisabete Lima, Jorge Medeiros · 2024 · Applied Sciences
- Gramine Derivatives Targeting Ca2+ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative DiseasesRocío Lajarín-Cuesta, Carmen Nanclares, Juan-Alberto Arranz-Tagarro, Laura González‐Lafuente, Raquel L. Arribas, Monique Araújo de Brito, Luis Gandı́a, Cristóbal de los Rı́os · 2016 · Journal of Medicinal Chemistry
- Risk of neurodegenerative disease due to tau phosphorylation changes and arsenic exposure via drinking waterDavoud Pakzad, Vajihe Akbari, Mohammad Reza Sepand, Mehdi Aliomrani · 2021 · Toxicology Research
- Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain InjuryWen Hui Hu, Yunn Chyn Tung, Yanchong Zhang, Fei Liu, Khalid Iqbal · 2018 · Journal of Alzheimer s Disease
- Generation of tau dephosphorylation-targeting chimeras for the treatment of Alzheimer’s disease and related tauopathiesJingfen Su, Yue Xiao, Linyu Wei, Huiyang Lei, Fei Sun, Weixia Wang, Jun Yin, Rui Xiong, Shihong Li, Pei Zhang et al. · 2024 · 中国科学通报:英文版
- Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive LearningZhuohan Yu, Yuning Yang, Xingjian Chen, Ka‐Chun Wong, Zhaolei Zhang, Yuming Zhao, Xiangtao Li · 2024 · Advanced Science
- Sex differences in the neuropathological hallmarks of Alzheimer’s disease: focus on cognitively intact elderly individualsYuting Hu, Jackson Tyler Boonstra, Hugo McGurran, Jochem Stormmesand, Arja A. Sluiter, Rawien A. Balesar, Ronald W. H. Verwer, Dick Frans Swaab, Ai‐Min Bao · 2021 · Neuropathology and Applied Neurobiology
- Neurodegeneration and convergent factors contributing to the deterioration of the cytoskeleton in Alzheimer's disease, cerebral ischemia and multiple sclerosis (Review)Johanna Andrea Gutiérrez Vargas, John Fredy Castro-Álvarez, José Fernando Zapata Berruecos, Komal Abdul‐Rahim, Anibal Arteaga‐Noriega · 2022 · Biomedical Reports
- DHCR24 Knockdown Induces Tau Hyperphosphorylation at Thr181, Ser199, Ser262, and Ser396 Sites via Activation of the Lipid Raft-Dependent Ras/MEK/ERK Signaling Pathway in C8D1A AstrocytesMeiting Mai, Xiaorou Guo, Yue Ming Huang, Wenbin Zhang, Yixuan Xu, Ying Zhang, Xiaojing Bai, Junfeng Wu, Hengbing Zu · 2022 · Molecular Neurobiology
- Cognitive Enhancers (Nootropics). Part 3: Drugs Interacting with Targets other than Receptors or Enzymes. Disease-modifying DrugsWolfgang Froestl, Andrea Pfeifer, Andreas Muhs · 2013 · Journal of Alzheimer s Disease
- Subtype and regional regulation of prion biomarkers in sporadic C reutzfeldt– J akob diseaseFranc Llorens, Saima Zafar, Belén Ansoleaga, Mohsin Shafiq, Rosi Blanco, Marga Carmona, Oriol Grau‐Rivera, Carlos Nos, Ellen Gelpí, José Antonio del Rı́o et al. · 2014 · Neuropathology and Applied Neurobiology
- Therapeutic Potential of the Hsp90/Cdc37 Interaction in Neurodegenerative DiseasesLiam Gracia, Gabriella Lora, Laura J. Blair, Umesh K. Jinwal · 2019 · Frontiers in Neuroscience
- Brain microRNAs dysregulation: Implication for missplicing and abnormal post-translational modifications of tau protein in Alzheimer’s disease and related tauopathiesMaryam Bazrgar, Pariya Khodabakhsh, Fatemeh Mohagheghi, Mercedes Prudencio, Abolhassan Ahmadiani · 2020 · Pharmacological Research
- Deciphering inhibitory activity of flavonoids against tau protein kinases: a coupled molecular docking and quantum chemical studyHassan Rasouli, Seyed Mohammad Bagher Hosseini Ghazvini, Reza Yarani, Ali Altıntaş, Saber Ghafari Nikoo Jooneghani, Teodorico C. Ramalho · 2020 · Journal of Biomolecular Structure and Dynamics
- Phosphorylated full‐length Tau interacts with 14‐3‐3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14‐3‐3 dimerJoão Filipe Neves, Olívia Petrvalská, Francesco Bosica, François‐Xavier Cantrelle, Hamida Merzougui, Gavin O’Mahony, Xavier Hanoulle, Tomáš Obšil, Isabelle Landrieu · 2020 · FEBS Journal
- Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer diseaseJangampalli Adi Pradeepkiran, Manne Munikumar, Arubala P. Reddy, P. Hemachandra Reddy · 2021 · Human Molecular Genetics
- Interactions between GSK3β and amyloid genes explain variance in amyloid burdenTimothy J. Hohman, Mary Ellen I. Koran, Tricia A. Thornton‐Wells · 2013 · Neurobiology of Aging
- Molecular mechanisms of neurofilament alterations and its application in assessing neurodegenerative disordersSrikripa Devarakonda, Shaik Basha, Anjana Pithakumar, L B Thoshna, Darshan Chikkanayakanahalli Mukunda, Jackson Rodrigues, K Ameera, Shimul Biswas, Aparna Ramakrishna Pai, Sushma Belurkar et al. · 2024 · Ageing Research Reviews
- REMOVED: Novel Treatment Strategies Using TiO2-Nanowired Delivery of Histaminergic Drugs and Antibodies to Tau With Cerebrolysin for Superior Neuroprotection in the Pathophysiology of Alzheimer's DiseaseAruna Sharma, Preeti Kumaran Menon, Ranjana Patnaik, Dafin Fior Muresanu, José Vicente Lafuente, Z. Ryan Tian, Asya Ozkızılcık, Herbert Mössler, Hari Shanker Sharma · 2017 · International review of neurobiology
- Macromolecular Structures and Proteins Interacting with the Microtubule Associated Tau ProteinJuan S. Jiménez · 2022 · Neuroscience
- Exploring the phytochemistry, pharmacognostic properties, and pharmacological activities of medically important plant Momordica CharantiaSwarupananda Mukherjee, Dipanjan Karati · 2023 · Pharmacological Research - Modern Chinese Medicine
- Prevention of Alzheimer's disease through diet: An exploratory reviewNusrat Zahan Bhuiyan, Md. Kamrul Hasan, Zimam Mahmud, Md. Sabbir Hossain, Atiqur Rahman · 2023 · Metabolism Open
- Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signalingYen-Ning Huang, Ching-I Lin, Hsiang Liao, Chin-Yu Liu, Yue-Hua Chen, Wan‐Chun Chiu, Shyh‐Hsiang Lin · 2016 · Neuroscience
- TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse modelJiyoen Kim, Bakhos Tadros, Yan Hong Wei Liang, Young Doo Kim, Cristian A. Lasagna‐Reeves, Jun Young Sonn, Dah‐eun Chloe Chung, Bradley T. Hyman, David M. Holtzman, Huda Yahya Zoghbi · 2024 · Nature Neuroscience
- GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer DiseaseHuey-Jiun Ko, Shean-Jaw Chiou, Yu‐Hui Wong, Yin-Hsuan Wang, Yun-Ling Lai, Chia‐Hua Chou, Chihuei Wang, Joon‐Khim Loh, Ann‐Shung Lieu, Jiin‐Tsuey Cheng et al. · 2019 · Journal of Clinical Medicine
- Fish oil protects the blood–brain barrier integrity in a mouse model of Alzheimer’s diseaseYouna Xie, Lingli Yan, Haitao Zeng, Weineng Chen, Jiahong Lu, Jian‐Bo Wan, Huanxing Su, Xiaoli Yao · 2020 · Chinese Medicine
- The Structure Biology of Tau and Clue for Aggregation Inhibitor DesignDan Wang, Xianlong Huang, Lu Yan, Luo‐Qi Zhou, Yan Chang, Jinhu Wu, Zhengding Su, Yongqi Huang · 2021 · The Protein Journal
- ARN25068, a versatile starting point towards triple GSK-3β/FYN/DYRK1A inhibitors to tackle tau-related neurological disordersStefania Demuro, Conall Sauvey, Shailesh Kumar Tripathi, Rita Maria Concetta Di Martino, Da Shi, Jose Antonio Ortega, Debora Russo, Beatrice Balboni, Barbara Giabbai, Paola Storici et al. · 2021 · European Journal of Medicinal Chemistry
- Marine Organisms as Alkaloid Biosynthesizers of Potential Anti-Alzheimer AgentsElisabete Lima, Jorge Medeiros · 2022 · Marine Drugs
- Microtubules as Regulators of Neural Network Shape and Function: Focus on Excitability, Plasticity and MemoryFernando Peña‐Ortega, Ángel Abdiel Robles-Gómez, Lorena Xolalpa Cueva · 2022 · Cells
- Plant‐derived peptides for the improvement of Alzheimer's disease: Production, functions, and mechanismsLike Lin, Cong Li, Tingting Li, Jingyi Zheng, Yu Shu, Jingjing Zhang, Yehua Shen, Difeng Ren · 2023 · Food Frontiers
- Quantitative Expression Analysis of APP Pathway and Tau Phosphorylation-Related Genes in the ICV STZ-Induced Non-Human Primate Model of Sporadic Alzheimer’s DiseaseSang-Je Park, Young-Hyun Kim, Gyu-Hwi Nam, Se-Hee Choe, Sang‐Rae Lee, Sun‐Uk Kim, Jisu Kim, Bo‐Woong Sim, Bong‐Seok Song, Kang-Jin Jeong et al. · 2015 · International Journal of Molecular Sciences
- ERK (MAPK) does not phosphorylate tau under physiological conditions in vivo or in vitroAnastasia Noël, Isabelle Poitras, Jacinthe Julien, Franck R. Petry, Françoise Morin, Jean Charron, Emmanuel Planel · 2014 · Neurobiology of Aging
- NLRP3-mediated autophagy dysfunction links gut microbiota dysbiosis to tau pathology in chronic sleep deprivationNa Zhao, 东南大学医学院神经内科, 江苏 南京 210009, 中国, Chen Xiu, Qiu-Gu Chen, Xue-Ting Liu, Fan Geng, Mengmeng Zhu, Fuling Yan, Zhijun Zhang, Qingguo Ren et al. · 2024 · 动物学研究
- Hyperphosphorylation of tau by GSK-3β in Alzheimer’s disease: The interaction of Aβ and sphingolipid mediators as a therapeutic targetMaja Jazvinšćak Jembrek, Mirjana Babić Leko, Nela Pivac, Patrick R. Hof, Goran Šimić · 2013 · Translational Neuroscience
- Therapeutic and diagnostic challenges for frontotemporal dementiaSimon Dâ€TMAlton, Jada M. Lewis · 2014 · Frontiers in Aging Neuroscience
- SPR and electrochemical analyses of interactions between CYP3A4 or 3A5 and cytochrome b5Oksana V. Gnedenko, Evgeniy O. Yablokov, Sergey A. Usanov, Dzmitry Mukha, Г. В. Сергеев, Tatiana V. Bulko, Alexey V. Kuzikov, Natalia E. Moskaleva, Victoria V. Shumyantseva, Alexis S. Ivanov et al. · 2014 · Chemical Physics Letters
- Subchronic exposure to acrylamide caused behaviour disorders and related pathological and molecular changes in rat cerebellumYing Liu, Dandan Yan, Yiqi Wang, Xing Zhang, Na Wang, Yang Jiao, Hong Yan · 2021 · Toxicology Letters
- Passive immunization against phosphorylated tau improves features of Huntington's disease pathologyAlpaugh, Melanie, Masnata, Maria, de Rus Jacquet, Aurelie, Lepinay, Eva, Denis, Hélèna L., Saint-Pierre, Martine, Davies, Peter, Planel, Emmanuel, Cicchetti, Francesca · 2022 · Molecular Therapy
- Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathologyShengnan Zhang, Yi Zhu, Jinxia Lu, Zhenying Liu, Amanda G. Lobato, Wen Zeng, Jiaqi Liu, Jiali Qiang, Shuyi Zeng, Yaoyang Zhang et al. · 2022 · eLife
- Ser422 phosphorylation blocks human Tau cleavage by caspase-3: Biochemical implications to Alzheimer’s DiseasePriya Sandhu, Mansur M. Naeem, Chunyu Lu, Premkumari Kumarathasan, James Gomes, Ajoy Basak · 2016 · Bioorganic & Medicinal Chemistry Letters
- β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional ProfilingWeiying Liu, Feng-Xian Sun, Moxin Wan, Fang Jiang, Xiangyu BO, Laixiang Lin, Hua Tang, Shumei Xu · 2018 · Frontiers in Pharmacology
- Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of TauopathyTariq Ahmed, Ann Van der Jeugd, Raphaëlle Caillierez, Luc Buée, David L Blum, Rudi D’Hooge, Detlef Balschun · 2020 · Frontiers in Molecular Neuroscience
- Inhibition of GSK_3β by Iridoid Glycosides of Snowberry (Symphoricarpos albus) Effective in the Treatment of Alzheimer’s Disease Using Computational Drug Design MethodsMarzieh Eskandarzadeh, Parastou Kordestani-Moghadam, Saeed Pourmand, Javad Khalili Fard, Bijan Almassian, Sajjad Gharaghani · 2021 · Frontiers in Chemistry
- Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal PlasticityLaura Llorach-Parés, Ened Rodríguez-Urgellés, Alfons Nonell‐Canals, Jordi Alberch, Conxita Àvila, Melchor Sánchez-Martínez, Albert Giralt · 2020 · Biomolecules
- Stoichiometric 14-3-3ζ binding promotes phospho-Tau microtubule dissociation and reduces aggregation and condensationJanine Hochmair, Maxime C. M. van den Oetelaar, Leandre M. Ravatt, Lisa Diez, Lenne J. M. Lemmens, Renata Ponce-Lina, Rithika Sankar, Maximilian Franck, Gesa Nolte, Ekaterina Semenova et al. · 2025 · Communications Biology
- Inhibition of Alzheimer’s amyloid-β42 peptide aggregation by a bi-functional bis-tryptoline triazole: key insights from molecular dynamics simulationsSimranjeet Singh Narang, Deepti Goyal, Bhupesh Goyal · 2019 · Journal of Biomolecular Structure and Dynamics
- Anti-Inflammatory and Tau Phosphorylation–Inhibitory Effects of EupatinChing-Hsuan Chou, Kai‐Cheng Hsu, Tony Eight Lin, Chia‐Ron Yang · 2020 · Molecules
- Sauna-like conditions or menthol treatment reduce tau phosphorylation through mild hyperthermiaIsabelle Guisle, Geoffrey Canet, Séréna Petry, Parissa Fereydouni-Forouzandeh, Françoise Morin, Rémi Kérauden, Robert A. Whittington, Frédéric Calon, Sébastien S. Hébert, Emmanuel Planel · 2022 · Neurobiology of Aging
- Heparan Sulfate Proteoglycans in TauopathyYanan Zhu, Lauren A. Gandy, Fuming Zhang, Jian Liu, Chunyu Wang, Laura J. Blair, Robert J. Linhardt, Lianchun Wang · 2022 · Biomolecules
- Disruption of DYRK1A-induced hyperphosphorylation of amyloid-beta and tau protein in Alzheimer’s disease: An integrative molecular modeling approachRohit Shukla, Anuj Kumar, David J. Kelvin, Tiratha Raj Singh · 2023 · Frontiers in Molecular Biosciences
- Neuroprotection and Mechanism of Gas-miR36-5p from Gastrodia elata in an Alzheimer’s Disease Model by Regulating Glycogen Synthase Kinase-3βZhongteng Lu, Jianyuan Fu, Guang Wu, Zhecheng Yang, Xiaoqi Wu, Dan Wang, Zhengying You, Zuoming Nie, Qing Sheng · 2023 · International Journal of Molecular Sciences
- Integrated analysis of differential gene expression profiles in hippocampi to identify candidate genes involved in Alzheimer's diseaseWanhua Hu, Xiaodong Lin, KELONG CHEN · 2015 · Molecular Medicine Reports
- Fragile X mental retardation protein: from autism to neurodegenerative diseaseHansen Wang · 2015 · Frontiers in Cellular Neuroscience
- GRK5 influences the phosphorylation of tau via GSK3β and contributes to Alzheimer's diseaseJianghao Zhao, Xiaohui Li, Xiongjin Chen, Yujie Cai, Yan Wang, Wenjing Sun, Hui Mai, Jingqi Yang, Weihao Fan, Pei Tang et al. · 2018 · Journal of Cellular Physiology
- Neuroinflammation and Alzheimer's disease: Unravelling the molecular mechanismsAniket Kakkar, Harpreet Singh, Bhuvnesh Kumar Singh, Arvind Kumar, Arun Kumar Mishra, Hitesh Chopra · 2025 · Journal of Alzheimer s Disease
- Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assaysAlex Crowe, Mark J. Henderson, Johnathon David Anderson, Steven A. Titus, Alexey V. Zakharov, Anton M. Simeonov, Arjan Buist, Charlotte Delay, Diederik Moechars, John Q. Trojanowski et al. · 2020 · Journal of Biological Chemistry
- Rutaecarpine Ameliorated High Sucrose-Induced Alzheimer's Disease Like Pathological and Cognitive Impairments in MiceZhao Bin, Yi Wang, Rui Liu, Xiaoli Jia, Nan Hu, Xingwei An, Chenguang Zheng, Chong Chen, Hongtao Sun, Feng Chen et al. · 2020 · Rejuvenation Research
- Targeting Tau to Treat Clinical Features of Huntington's DiseaseMaria Masnata, Shireen Salem, Aurélie de Rus Jacquet, Mehwish Anwer, Francesca Cicchetti · 2020 · Frontiers in Neurology
- Cytomegalovirus infection induces Alzheimer’s disease-associated alterations in tauMody, Prapti H., Marvin, Kelsey N., Hynds, DiAnna L., Hanson, Laura K. · 2023 · Journal of NeuroVirology
- Tau Accumulation in the Spinal Cord Contributes to Chronic Inflammatory Pain by Upregulation of IL-1β and BDNFShuxia Zhang, Yeru Chen, Yongjie Wang, Hongwei Wang, Dandan Yao, Gang Chen · 2023 · Neuroscience Bulletin
- Serotonin Receptors as a Potential Target in the Treatment of Alzheimer’s DiseaseDmitry V. Eremin, Elena M. Kondaurova, Aleksander Ya Rodnyy, Camilla A. Molobekova, Dmitry Anatolievich Kudlay, Vladimir S. Naumenko · 2023 · Biochemistry (Moscow)
- Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease modelsLinyan Duan, Zhizhong Hao, Rong Ji, Xingfan Li, Hao Wang, Yujing Su, Fangxia Guan, Shanshan Ma · 2024 · International Journal of Biological Macromolecules
- Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamicsKateřina Melková, Vojtěch Zapletal, Séverine Jansen, Erik Nomilner, Milan Zachrdla, Jozef Hritz, Jiří Nováček, Markus Zweckstetter, Malene Ringkjøbing Jensen, Martin J Blackledge et al. · 2018 · Journal of Biological Chemistry
- Streptocyclinones A and B ameliorate Alzheimer's disease pathological processes in vitroRebeca Alvariño, Eva Alonso, Rodney Lacret, Daniel Oves‐Costales, Olga Genilloud, Fernando Reyes, Amparo Alfonso, Luis Miguel Botana · 2018 · Neuropharmacology
- Chronic microglial inflammation promotes neuronal lactate supply but impairs its utilization in primary rat astrocyte-neuron co-culturesYi Wang, Jie Li, Meng-Yue Wang, Zhi-Yong Pan, Zhiqiang Li, Ze-Fen Wang · 2022 · Biochemical and Biophysical Research Communications
- Patient-Derived Fibroblasts With Presenilin-1 Mutations, That Model Aspects of Alzheimer’s Disease Pathology, Constitute a Potential Object for Early DiagnosisGustavo López-Toledo, Maria‐del‐Carmen Silva‐Lucero, Jorge Herrera‐Díaz, David-Erasmo García, José‐Antonio Arias‐Montaño, María del Carmen Cárdenas‐Aguayo · 2022 · Frontiers in Aging Neuroscience
- Long‐Term High‐Fat Diet Consumption Aggravates β‐Amyloid Deposition and Tau Pathology Accompanied by Microglial Activation in an Alzheimer's Disease ModelZheng Liang, Xiaokang Gong, Yang Zhao, Yanna Zhao, Jing Yu, Tiantian Huang, Chaoqing Yang, Liangwei Wu, Mengbing Huang, Xiaochuan Wang et al. · 2024 · Molecular Nutrition & Food Research
- Development of tau phosphorylation-targeting therapies for the treatment of neurodegenerative diseasesJingfen Su, Yue Xiao, Xiaochuan Wang, Jie Zheng, Jian‐Zhi Wang · 2024 · Medicine Plus
- Tibolone modulates neuronal plasticity through regulating Tau, GSK3β/Akt/PI3K pathway and CDK5 p35/p25 complexes in the hippocampus of aged male miceChristian Guerra‐Araiza, Teresa Neri-Gómez, Judith Espinosa‐Raya, Sofía Y. Díaz-Cintra, Julia J. Segura-Uribe, Sandra Adela Orozco-Suárez, Juan Manuel Gallardo · 2017 · Neural Regeneration Research
- Emerging roles of protein kinases in microglia-mediated neuroinflammationSun Hwa Lee, Kyoungho Suk · 2017 · Biochemical Pharmacology
- Phlorizin administration ameliorates cognitive deficits by reducing oxidative stress, tau hyper‐phosphorylation, and neuroinflammation in a rat model of Alzheimer’s diseaseYuan Tian, Weibing Lu, Haohua Deng, Fan Yang, Yan Guo, Ling Gao, Yancheng Xu · 2018 · Journal of Food Biochemistry
- Early detection and personalized medicine: Future strategies against Alzheimer's diseaseAntonio Di Meco, Robert J. Vassar · 2020 · Progress in molecular biology and translational science
- Astrocyte transport of glutamate and neuronal activity reciprocally modulate tau pathology in DrosophilaJason Kilian, Heng-Wei Hsu, Kenneth Mata, Fred W. Wolf, Masashi Kitazawa · 2017 · Neuroscience
- Forskolin Induces Hyperphosphorylation of Tau Accompanied by Cell Cycle Reactivation in Primary Hippocampal NeuronsWang, Hai-Hong, Li, Yan, Li, Ang, Yan, Fang, Li, Zhen-Lin, Liu, Zhong-Ying, Zhang, Lei, Zhang, Jian, Dong, Wei-Ren, Zhang, Lin · 2018 · Molecular Neurobiology