Cited by 176Cholesterol and Lipid MetabolismParaoxonase enzyme and polymorphismsLipoproteins and Cardiovascular Health

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Structural modifications of HDL and functional consequences

Ferretti, Gianna, Bacchetti, Tiziana, Nègre-Salvayre, Anne, Salvayre, Robert, Dousset, Nicole, Curatola, Giovanna·2006·Atherosclerosis

DOI 10.1016/j.atherosclerosis.2005.08.008

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Abstract

High density lipoproteins (HDL) are susceptible to structural modifications mediated by various mechanisms including oxidation, glycation, homocysteinylation or enzymatic degradation. Structural alterations of HDL may affect their functional and atheroprotective properties. Oxidants, such as hypochlorous acid, peroxyl radicals, metal ions, peroxynitrite, lipoxygenases and smoke extracts, can alter both surface and core components of HDL. The formation of lipid peroxidation derivatives, such as thiobarbituric acid reactive substances, conjugated dienes, lipid hydroperoxides and aldehydes, is associated with changes of physical properties (fluidity, molecular order) and of apoprotein conformation. Non-enzymatic glycation, generally associated with lipoxidation, leads to form irreversible complexes called advanced glycation end products. These HDL modifications are accompanied with altered biological activities of HDL and associated enzymes, including paraoxonase, CETP and LCAT. Homocysteine-induced modification of HDL is mediated by homocysteine-thiolactone, and can be prevented by a calcium-dependent thiolactonase/paraoxonase. Tyrosylation of HDL induces the formation of dimers and trimers of apo AI, and alters cholesterol efflux. Phospholipases and proteolytic enzymes can also modify HDL lipid and apoprotein structure. HDL modification induces generally the loss of their anti-inflammatory and cytoprotective properties. This could play a role in the pathogenesis of atherosclerosis and neurodegenerative diseases such as Alzheimer's disease.

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The role of lipid peroxidation and antioxidants in oxidative modification of LDL
Esterbauer, H., Gebicki, J. M., Puhl, H., & Jürgens, G. (1992) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(92)90181-f · Cited by 2,307
Homocysteine and vascular disease
McCully, K. S. (1996) · Nature Medicine · doi:10.1038/nm0496-386 · Cited by 705
Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.
Heinecke, J. W., Li, W., Daehnke, H. L., & Goldstein, J. A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53581-x · Cited by 485
High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors.
Bowry, V. W., Stanley, K. K., & Stocker, R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.21.10316 · Cited by 479
Lipoprotein receptors in the nervous system
Herz, J., & Bock, H. H. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135342 · Cited by 457
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
McCance, D. R., Dyer, D. G., Dunn, J. A., Bailie, K., Thorpe, S. R., Baynes, J., & Lyons, T. J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116482 · Cited by 444
Calcium-dependent Human Serum Homocysteine Thiolactone Hydrolase
Jakubowski, H. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.6.3957 · Cited by 399
Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels
Jakubowski, H. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.15.2277 · Cited by 372
Homocysteine theory of arteriosclerosis
McCully, K. S., & Wilson, R. B. (1975) · Atherosclerosis · doi:10.1016/0021-9150(75)90004-0 · Cited by 336
Oxidation of High Density Lipoproteins
Garner, B., Waldeck, A. R., Witting, P. K., Rye, K.-A., & Stocker, R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.11.6088 · Cited by 324

Show all 70 references

Research works printed but not linked: 1

Keller, 2000, Oxidized high-density lipoprotein induces neuron death, Exp Neurol, 161, 621, 10.1006/exnr.1999.7276 · DOI

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Grundy, S. M. (2008) · European Heart Journal Supplements · doi:10.1093/eurheartj/sum044 · Cited by 26
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Polesel, J., Negri, E., Serraino, D., Parpinel, M. T., Barzan, L., Libra, M., Bosetti, C., Garavello, W., Montella, M., Vecchia, C. L., et al. (2012) · British Journal of Cancer · doi:10.1038/bjc.2012.413 · Cited by 25
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Le, N. (1997) · Current Opinion in Lipidology · doi:10.1097/00041433-199704000-00015 · Cited by 25
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Morales, N. P., Charlermchoung, C., Luechapudiporn, R., Yamanont, P., Fucharoen, S., & Chantharaksri, U. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.09.106 · Cited by 14
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Callegari, E., Norata, G. D., Inoue, H., & Catapano, A. L. (2006) · International Journal of Molecular Medicine · doi:10.3892/ijmm.18.1.209 · Cited by 14
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Morales, N. P., Cherlermchoung, C., Fucharoen, S., & Chantharaksri, U. (2007) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2007.145 · Cited by 13
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Authors: Ferretti, G., Bacchetti, T., Nègre-Salvayre, A., Salvayre, R., Dousset, N., & Curatola, G.
Affiliations: Inserm (FR)
Université Toulouse III - Paul Sabatier (FR)
Corresponding author: Ferretti, Gianna
ORCID: Ferretti, Gianna
Bacchetti, Tiziana
Curatola, Giovanna
Venue: Atherosclerosis
Publisher: Elsevier BV
Published: 2006-01
Volume: 184
Issue: 1
Pages: 1-7
ISSN: 0021-9150 (ISSN-L)
DOI: 10.1016/j.atherosclerosis.2005.08.008
OpenAlex: W2085222803
Cited by: 176
References: 70
Citations by year: 2026: 2 · 2025: 4 · 2024: 2 · 2023: 7 · 2022: 8 · 2021: 2 · 2020: 9 · 2019: 11 · 2018: 3 · 2017: 9 · 2016: 5 · 2015: 9 · 2014: 9 · 2013: 9 · 2012: 6
FWCI: 2.38
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Atherosclerosis (publishedVersion)
PubMed (publishedVersion)
Università Politecnica delle Marche (Università Politecnica delle Marche) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Paraoxonase enzyme and polymorphisms
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords: high-density lipoprotein, HDL oxidation, lipid peroxidation, glycation, advanced glycation end products, homocysteine thiolactone, paraoxonase, cholesteryl ester transfer protein, lecithin:cholesterol acyltransferase, cholesterol efflux, anti-inflammatory activity, Alzheimer's disease, neurodegenerative diseases
MeSH terms: Antioxidants, Humans, Cholesterol, HDL, Lipid Peroxidation, Atherosclerosis

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Structural modifications of HDL and functional consequences

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