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Cholesterol modulates LRP5 expression in the vessel wall
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Aortas from Lrp5-/- mice show less lipid content than those from Wt mice.
“Furthermore, aortas from Lrp5 -/-mice show less lipid content than those from Wt mice 27,28”
From Canonical Wnt pathway and the LDL receptor superfamily in neuronal cholesterol homeostasis and function (2024) · cites this paper as [27]
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Khovidhunkit, W., Kim, M.-S., Memon, R. A., Shigenaga, J. K., Moser, A. H., Feingold, K. R., & Grunfeld, C. (2004) · Journal of Lipid Research · doi:10.1194/jlr.r300019-jlr200 · Cited by 1,481
Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease
Nissen, S. E., Tuzcu, E. M., Schoenhagen, P., Crowe, T., Sasiela, W. J., Tsai, J., Orazem, J., Magorien, R. D., O'Shaughnessy, C., & Ganz, P. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa042000 · Cited by 1,325
Chan, K. L., Teo, K., Dumesnil, J. G., Ni, A., & Tam, J. (2010) · Circulation · doi:10.1161/circulationaha.109.900027 · Cited by 815
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Research works printed but not linked: 54
- Stancu, 2012, Dual role of lipoproteins in endothelial cell dysfunction in atherosclerosis, Cell Tissue Res, 349, 433, 10.1007/s00441-012-1437-1 · DOI
- Turkish, 2009, The genetics of neutral lipid biosynthesis: an evolutionary perspective, Am J Physiol Endocrinol Metab, 297, E19, 10.1152/ajpendo.90898.2008 · DOI
- Berenson, 1998, Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. the Bogalusa heart study, N Engl J Med, 338, 1650, 10.1056/NEJM199806043382302 · DOI · Paper page
- Egusa, 2004, Lifestyle, serum lipids and coronary artery disease: comparison of Japan with the United States, J Atheroscler Thromb, 11, 304, 10.5551/jat.11.304 · DOI
- Kramsch, 1971, The protein and lipid composition of arterial elastin and its relationship to lipid accumulation in the atherosclerotic plaque, J Clin Invest, 50, 1666, 10.1172/JCI106656 · DOI
- Suarna, 1995, Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of alpha-tocopherol and ascorbate, Arterioscler Thromb Vasc Biol, 15, 1616, 10.1161/01.ATV.15.10.1616 · DOI
- Mackness, 1997, Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A-I in the human artery wall with the progression of atherosclerosis, Arterioscler Thromb Vasc Biol, 17, 1233, 10.1161/01.ATV.17.7.1233 · DOI
- Lang, 1970, Lipid droplets in atherosclerotic fatty streaks of human aorta, J Clin Invest, 49, 1479, 10.1172/JCI106365 · DOI
- Hiltunen, 1998, Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lesions: marked induction of scavenger receptor and VLDL receptor expression during lesion development, Circulation, 97, 1079, 10.1161/01.CIR.97.11.1079 · DOI
- Llorente-Cortés, 2006, Cholesteryl esters of aggregated LDL are internalized by selective uptake in human vascular smooth muscle cells, Arterioscler Thromb Vasc Biol, 26, 117, 10.1161/01.ATV.0000193618.32611.8b · DOI
- Borrell-Pagès, 2011, Wnt pathway activation, cell migration, and lipid uptake is regulated by low-density lipoprotein receptor-related protein 5 in human macrophages, Eur Heart J, 32, 2841, 10.1093/eurheartj/ehr062 · DOI · Paper page
- Fujino, 2003, Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion, Proc Natl Acad Sci U. S. A, 100, 229, 10.1073/pnas.0133792100 · DOI · Paper page
- Magoori, 2003, Severe hypercholesterolemia, impaired fat tolerance, and advanced atherosclerosis in mice lacking both low density lipoprotein receptor-related protein 5 and apolipoprotein E, J Biol Chem, 278, 11331, 10.1074/jbc.M211987200 · DOI · Paper page
- Kamal-Eldin, 2009, Plant sterols and stanols as cholesterol-lowering ingredients in functional foods, Recent Pat Food Nutr Agric, 1, 1, 10.2174/2212798410901010001 · DOI
- Othman, 2011, Beyond cholesterol-lowering effects of plant sterols: clinical and experimental evidence of anti-inflammatory properties, Nutr Rev, 69, 371, 10.1111/j.1753-4887.2011.00399.x · DOI
- Weingärtner, 2011, Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice, Cardiovasc Res, 90, 484, 10.1093/cvr/cvr020 · DOI
- Rideout, 2012, Metabolic and genetic factors modulating subject specific LDL-C responses to plant sterol therapy, Can J Physiol Pharmacol, 90, 509, 10.1139/y2012-060 · DOI
- Calpe-Berdiel, 2005, Changes in intestinal and liver global gene expression in response to a phytosterol-enriched diet, Atherosclerosis, 181, 75, 10.1016/j.atherosclerosis.2004.11.025 · DOI
- Weingärtner, 2008, Vascular effects of diet supplementation with plant sterols, J Am Coll Cardiol, 51, 1553, 10.1016/j.jacc.2007.09.074 · DOI
- Nashed, 2005, Antiatherogenic effects of dietary plant sterols are associated with inhibition of proinflammatory cytokine production in Apo E-KO mice, J Nutr, 135, 2438
- Sabeva, 2011, Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells, J Nutr Biochem, 22, 777, 10.1016/j.jnutbio.2010.07.002 · DOI
- Bouic, 1999, The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: inhibition of post marathon immune suppression and inflammation, Int J Sports Med, 20, 258, 10.1055/s-2007-971127 · DOI
- Devaraj, 2006, Reduced-calorie orange juice beverage with plant sterols lowers C-reactive protein concentrations and improves the lipid profile in human volunteers, Am J Clin Nutr, 84, 756, 10.1093/ajcn/84.4.756 · DOI
- Holmen, 2004, Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6, J Bone Min Res Off J Am Soc Bone Min Res, 19, 2033, 10.1359/jbmr.040907 · DOI
- Lindvall, 2006, The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis, J Biol Chem, 281, 35081, 10.1074/jbc.M607571200 · DOI
- Cui, 2011, Lrp5 functions in bone to regulate bone mass, Nat Med, 17, 684, 10.1038/nm.2388 · DOI
- Wu, 2009, The effects of phytosterols/stanols on blood lipid profiles: a systematic review with meta-analysis, Asia Pac J Clin Nutr, 18, 179
- Koh, 2004, Association between bone mineral density and LDL receptor-related protein 5 gene polymorphisms in young Korean men, J Korean Med Sci, 19, 407, 10.3346/jkms.2004.19.3.407 · DOI
- Urano, 2009, A1330V variant of the low-density lipoprotein receptor-related protein 5 (LRP5) gene decreases Wnt signaling and affects the total body bone mineral density in Japanese women, Endocr J, 56, 625, 10.1507/endocrj.K09E-133 · DOI
- Suwazono, 2006, G-protein beta 3 subunit polymorphism C1429T and low-density lipoprotein receptor-related protein 5 polymorphism A1330V are risk factors for hypercholesterolemia in Japanese males–a prospective study over 5 years, Metabolism, 55, 751, 10.1016/j.metabol.2006.01.011 · DOI
- Jiang, 2010, Association of LPR5 polymorphism with bone mass density and cholesterol level in population of Chinese Han, Exp Clin Endocrinol Diabetes Off J Ger Soc Endocrinol Ger Diabetes Assoc, 118, 388, 10.1055/s-0029-1225613 · DOI
- Penumathsa, 2007, Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat, J Mol Cell Cardiol, 42, 508, 10.1016/j.yjmcc.2006.10.018 · DOI
- Kim, 1998, A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E, J Biochem (Tokyo), 124, 1072, 10.1093/oxfordjournals.jbchem.a022223 · DOI · Paper page
- Rajamannan, 2011, The role of Lrp5/6 in cardiac valve disease: experimental hypercholesterolemia in the ApoE-/-/Lrp5-/- mice, J Cell Biochem, 112, 2987, 10.1002/jcb.23221 · DOI
- Rajamannan, 2005, Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway, Circulation, 112, I229, 10.1161/01.CIRCULATIONAHA.104.524306 · DOI
- Hutchins, 2011, Electrospray MS/MS reveals extensive and nonspecific oxidation of cholesterol esters in human peripheral vascular lesions, J Lipid Res, 52, 2070, 10.1194/jlr.M019174 · DOI
- Kruth, 1984, Localization of unesterified cholesterol in human atherosclerotic lesions. Demonstration of filipin-positive, oil-red-O-negative particles, Am J Pathol, 114, 201
- Guyton, 1994, Development of the atherosclerotic core region. Chemical and ultrastructural analysis of microdissected atherosclerotic lesions from human aorta, Arterioscler Thromb J Vasc Biol Am Heart Assoc, 14, 1305, 10.1161/01.ATV.14.8.1305 · DOI
- Chen, 2010, Cholesterol in human atherosclerotic plaque is a marker for underlying disease state and plaque vulnerability, Lipids Health Dis, 9, 61, 10.1186/1476-511X-9-61 · DOI
- Borrell-Pagès, 2014, LRP5 negatively regulates differentiation of monocytes through abrogation of Wnt signalling, J Cell Mol Med, 18, 314, 10.1111/jcmm.12190 · DOI
- Feingold, 2012, Mechanisms of triglyceride accumulation in activated macrophages, J Leukoc Biol, 92, 829, 10.1189/jlb.1111537 · DOI
- Lopes-Virella, 1987, Low density lipoprotein metabolism in human macrophages stimulated with microbial or microbial-related products, Arterioscler Dallas Tex, 7, 176, 10.1161/01.ATV.7.2.176 · DOI
- Funk, 1993, Lipopolysaccharide stimulation of RAW 264.7 macrophages induces lipid accumulation and foam cell formation, Atherosclerosis, 98, 67, 10.1016/0021-9150(93)90224-I · DOI
- Martin, 2005, Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3, Nat Immunol, 6, 777, 10.1038/ni1221 · DOI
- Ahn, 2010, Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/beta-catenin signaling, Am J Physiol Cell Physiol, 298, C1510, 10.1152/ajpcell.00369.2009 · DOI
- Kim, 1950, Wnt5a induces endothelial inflammation via beta-catenin-independent signaling, J Immunol Balt Md, 2010, 1274
- Whyte, 2012, Wnt signaling and injury repair, Cold Spring Harb Perspect Biol, 4, a008078, 10.1101/cshperspect.a008078 · DOI
- Rideout, 2010, Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice, Mol Nutr Food Res, 54, S7, 10.1002/mnfr.201000027 · DOI
- Naumann, 2008, The baseline serum lipoprotein profile is related to plant stanol induced changes in serum lipoprotein cholesterol and triacylglycerol concentrations, J Am Coll Nutr, 27, 117, 10.1080/07315724.2008.10719683 · DOI
- Plat, 2009, A plant stanol yogurt drink alone or combined with a low-dose statin lowers serum triacylglycerol and non-HDL cholesterol in metabolic syndrome patients, J Nutr, 139, 1143
- Moghadasian, 1997, “Tall oil”-derived phytosterols reduce atherosclerosis in ApoE-deficient mice, Arterioscler Thromb Vasc Biol, 17, 119, 10.1161/01.ATV.17.1.119 · DOI
- Ntanios, 2003, Effects of various amounts of dietary plant sterol esters on plasma and hepatic sterol concentration and aortic foam cell formation of cholesterol-fed hamsters, Atherosclerosis, 169, 41, 10.1016/S0021-9150(03)00132-1 · DOI
- Plat, 2006, Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols, J Lipid Res, 47, 2762, 10.1194/jlr.M600346-JLR200 · DOI
- Weststrate, 1998, The clinical relevance of the waterlow pressure sore risk scale in the ICU, Intensive Care Med, 24, 815, 10.1007/s001340050671 · DOI
Cited by
Sorted by citations
Borrell-Pages, M., Luquero, A., Vilahur, G., Padró, T., & Badimon, L. (2024) · Cardiovascular Research · doi:10.1093/cvr/cvad159 · Cited by 10
Metadata
- Authors
- Borrell-Pages, M., Romero, J. C., & Badimon, L.
- Venue
- Atherosclerosis
- Publisher
- Elsevier BV
- Published
- 2014-08
- Volume
- 235
- Issue
- 2
- Pages
- 363-370
- ISSN
- 0021-9150
- Cited by
- 27
- References
- 3
- Language
- en
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