Cited by 111

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Severe Hypercholesterolemia, Impaired Fat Tolerance, and Advanced Atherosclerosis in Mice Lacking Both Low Density Lipoprotein Receptor-related Protein 5 and Apolipoprotein E

Magoori, Kenta, Kang, Man-Jong, Ito, Mitsuko R., Kakuuchi, Hajime, Ioka, Ryoichi X., Kamataki, Akihisa, Kim, Dong-Ho, Asaba, Hiroshi, Iwasaki, Satoshi, Takei, Yumiko A., Sasaki, Masako, Usui, Shinichi, Okazaki, Mitsuyo, Takahashi, Sadao, Ono, Masao, Nose, Masato, Sakai, Juro, Fujino, Takahiro, Yamamoto, Tokuo T.·2003·Journal of Biological Chemistry

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Integrity signals

Registry

Crossref · 10.1074/jbc.m211987200

Cites

5 of 5 references verified0 citation errors · 0 not checkable

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Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Inactivation of LRP1 or LRP5 in hepatocytes has no effect on fasting plasma triglyceride levels.

    “However, inactivation of LRP1 or LRP5 in hepatocytes has no effect on fasting plasma triglyceride levels (61, 63)”

    From Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice (2009) · cites this paper as [63]

    The Results (page unavailable) report that 16 hours of fasting increased VLDL-triglyceride in LRP5-knockout mice, contrary to the claimed lack of an effect. The study used LRP5-knockout mice, not hepatocyte-specific inactivation, and does not establish the LRP1 part of the sentence. (LLM, conf=0.86)

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  • Inactivation of LRP1 in the liver or systemic inactivation of LRP5 has no effect on lipoprotein clearance under normal physiological conditions.

    “LDLR deficiency leads to a large increase in levels of apoB-100-bearing cholesterol-rich LDL and an increase in the level of triglyceride-rich particles (49), whereas inactivation of LRP1 in the liver (15) or systemic inactivation of LRP5 has no effect on lipoprotein clearance under normal physiological conditions (58).”

    From Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members (2007) · cites this paper as [58]

    The Results (page unavailable) report that LRP5 deficiency alone had no significant effect on plasma cholesterol levels in mice fed normal chow. That does not establish unchanged lipoprotein clearance: the Results also report markedly impaired clearance of triglycerides after fat loading in LRP5-knockout mice. The paper does not address the sentence’s separate claim about liver LRP1 inactivation. (LLM, conf=0.86)

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Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 22

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  11. Nusse, 1992, Cell, 69, 1073, 10.1016/0092-8674(92)90630-U · DOI
  12. Wodarz, 1998, Annu. Rev. Cell Dev. Biol., 14, 59, 10.1146/annurev.cellbio.14.1.59 · DOI
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Metadata

Authors
Magoori, K., Kang, M.-J., Ito, M. R., Kakuuchi, H., Ioka, R. X., Kamataki, A., Kim, D.-H., Asaba, H., Iwasaki, S., Takei, Y. A., Sasaki, M., Usui, S., Okazaki, M., Takahashi, S., Ono, M., Nose, M., Sakai, J., Fujino, T., & Yamamoto, T. T.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2003-03
Volume
278
Issue
13
Pages
11331-11336
ISSN
0021-9258
Cited by
111
References
5
Language
en

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