The DOI matches its Crossref record; 124 of the 125 references it cites were found in a registry or an index.
Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism
Open accessAbstract
Apolipoprotein C-II (apoC-II) is a small exchangeable apolipoprotein found on triglyceride-rich lipoproteins (TRL), such as chylomicrons (CM) and very low-density lipoproteins (VLDL), and on high-density lipoproteins (HDL), particularly during fasting. ApoC-II plays a critical role in TRL metabolism by acting as a cofactor of lipoprotein lipase (LPL), the main enzyme that hydrolyses plasma triglycerides (TG) on TRL. Here, we present an overview of the role of apoC-II in TG metabolism, emphasizing recent novel findings regarding its transcriptional regulation and biochemistry. We also review the 24 genetic mutations in the APOC2 gene reported to date that cause hypertriglyceridemia (HTG). Finally, we describe the clinical presentation of apoC-II deficiency and assess the current therapeutic approaches, as well as potential novel emerging therapies.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“For instance, there was a negative relationship between the relative abundance of two Lachnospiraceae ASVs (ASV0048 & ASV0056) and methylation at a DMR nearby apolipoprotein C2, a gene implicated in metabolism of triglyceride-rich lipoproteins (TRLs) by acting as a cofactor of lipoprotein lipase (LPL), the main enzyme that hydrolyses plasma triglycerides on TRL59.”
From Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in AppNL-G-F, AppNL-F, and wild type mice (2021) · cites this paper as [59]
In the citing paper
“Apo C-II is a cofactor for LPL91,92”
From Clinical review on triglycerides (2020) · cites this paper as [92]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Doolittle, M. H., Neher, S. B., Ben-Zeev, O., Ling-Liao, J., Gallagher, C. M., Hosseini, M., Yin, F., Wong, H., Walter, P., & Péterfy, M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.049395 · Cited by 28
RetractedLipase maturation factor 1 is required for endothelial lipase activity
Ben-Zeev, O., Hosseini, M., Lai, C.-M., Ehrhardt, N., Wong, H., Cefalu, A. B., Noto, D., Averna, M. R., Doolittle, M. H., & Péterfy, M. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m011155 · Cited by 25
RetractedTriglycerides and cardiovascular disease
Nordestgaard, B. G., & Varbo, A. (2014) · The Lancet · doi:10.1016/s0140-6736(14)61177-6 · Cited by 1,419
Remnant Cholesterol as a Causal Risk Factor for Ischemic Heart Disease
Varbo, A., Benn, M., Tybjærg-Hansen, A., Jørgensen, A. B., Frikke-Schmidt, R., & Nordestgaard, B. G. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.08.1026 · Cited by 1,115
Hayhurst, G. P., Lee, Y.-H., Lambert, G., Ward, J. M., & Gonzalez, F. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.4.1393-1403.2001 · Cited by 1,107
Lipoprotein lipase: structure, function, regulation, and role in disease
Mead, J. R., Irvine, S. A., & Ramji, D. P. (2002) · Journal of Molecular Medicine · doi:10.1007/s00109-002-0384-9 · Cited by 962
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
Dewey, F. E., Gusarova, V., Dunbar, R. L., O’Dushlaine, C., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C. V., Bruse, S., Dansky, H. M., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1612790 · Cited by 885
Self-citationSegrest, J., Jones, M., Loof, H. D., Brouillette, C. G., Venkatachalapathi, Y. V., & Anantharamaiah, G. M. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41536-6 · Cited by 868
CLEARING FACTOR, A HEPARIN-ACTIVATED LIPOPROTEIN LIPASE
Korn, E. D. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66011-9 · Cited by 858
Adiels, M., Olofsson, S.-O., Taskinen, M.-R., & Borén, J. (2008) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.107.160192 · Cited by 820
Flagged first, then by citations
1 of the 125 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Herink M, IM, Medication induced changes in lipid and lipoproteins, In: De Groot LJ, C.G, Dungan K, et al (ed), Endotext (Internet), MDText.com, Inc., South Dartmouth (MA), Updated 2015 Jul 27, https://www.ncbi.nlm.nih.gov/books/NBK326739/.
Cited by
Sorted by citations
Items 101–200 of 232
Crystalline Cholesterol: The Material and Its Assembly Lines
Varsano, N., Capua-Shenkar, J., Leiserowitz, L., & Addadi, L. (2022) · Annual Review of Materials Research · doi:10.1146/annurev-matsci-081720-112639 · Cited by 12
Kraaijenhof, J. M., Tromp, T. R., Nurmohamed, N. S., Reeskamp, L. F., Langenkamp, M., Levels, J. H. M., Boekholdt, S. M., Wareham, N. J., Hoekstra, M., Stroes, E. S. G., et al. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.030476 · Cited by 11
Lightbourne, M., Wolska, A. T., Abel, B. S., Rother, K. I., Walter, M. F., Kushchayeva, Y. S., Auh, S., Shamburek, R. D., Remaley, A. T., Muniyappa, R., et al. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa191 · Cited by 11
Self-citationHarima, Y., Ariga, T., Kaneyasu, Y., Ikushima, H., Tokumaru, S., Shimamoto, S., Takahashi, T., Ii, N., Tsujino, K., Saito, A. I., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0259235 · Cited by 10
A Novel APOC2 Mutation in a Colombian Patient with Recurrent Hypertriglyceridemic Pancreatitis
Pinilla-Monsalve, G. D., Lores, J., Pachajoa, H., de León, J. D. L., López, A., Rodríguez‐Rojas, L. X., & Nastasi-Catanese, J. A. (2020) · The Application of Clinical Genetics · doi:10.2147/tacg.s243148 · Cited by 10
Deregulation of apolipoprotein C2 gene in cancer: A potential metabolic vulnerability
Liu, Y., Meng, Y., Zhang, T., & Alachkar, H. (2021) · Clinical and Translational Medicine · doi:10.1002/ctm2.406 · Cited by 10
Carrizales-Sánchez, A. K., Tamez‐Rivera, O., Gamboa, R. G., García‐Cayuela, T., Rodríguez-Gutiérrez, N. A., Elizondo‐Montemayor, L., García‐Rivas, G., Pacheco, A., Hernández‐Brenes, C., & Senés‐Guerrero, C. (2023) · Frontiers in Pediatrics · doi:10.3389/fped.2023.1193832 · Cited by 9
Kour, N., Bhagat, G., Singh, S., Bhatti, S. S., Arora, S., Singh, B., & Bhatia, A. (2023) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-023-01326-x · Cited by 9
Wolska, A. T., & Remaley, A. T. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818277-2.00009-1 · Cited by 9
Self-citationClinical associations between exercise and lipoproteins
Mendoza, M. F., & Lavie, C. J. (2022) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000848 · Cited by 9
Pérez‐Vega, K. A., Castañer, O., Sanllorente, A., Lassale, C. M., Ros, E., Pintó, X., Estruch, R., Salas‐Salvadó, J., Corella, D., Alonso‐Gómez, Á. M., et al. (2022) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202200338 · Cited by 8
Sviridov, D. O., Dasseux, A., Reimund, M., Pryor, M., Drake, S. K., Jarin, Z., Wolska, A. T., Pastor, R. W., & Remaley, A. T. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1223920 · Cited by 8
Self-citationSevere Combined Dyslipidemia With a Complex Genetic Basis
Le, R. T., Abbas, M., McIntyre, A. D., & Hegele, R. A. (2019) · Journal of Investigative Medicine High Impact Case Reports · doi:10.1177/2324709619877050 · Cited by 9
Li, L., Wang, X., Fu, X., Huang, Y., Wen, Y. R., Xu, Q., He, X., Wang, K., Huang, S., & Lv, Z. (2020) · Gene · doi:10.1016/j.gene.2020.144364 · Cited by 9
Does Proteomic Mirror Reflect Clinical Characteristics of Obesity?
Kiseleva, O. I., Arzumanian, V. A., Poverennaya, E. V., Pyatnitskiy, M. A., Ilgisonis, E. V., Zgoda, V. G., Plotnikova, O. A., KhKh, S., Лисица, А. В., Tutelyan, V. A., et al. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11020064 · Cited by 9
Wu, Y., Hu, Y., & Li, G. N. (2021) · BMC Pediatrics · doi:10.1186/s12887-021-02875-x · Cited by 10
Vitamin D immune modulation of the anti-inflammatory effects of HDL-associated proteins
Mousa, H., & Zughaier, S. M. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-025-02639-x · Cited by 9
Gene transfer and genome editing for familial hypercholesterolemia
Canepari, C., & Cantore, A. (2023) · Frontiers in Molecular Medicine · doi:10.3389/fmmed.2023.1140997 · Cited by 11
Comparative iTRAQ Proteomics Reveals Multiple Effects of Selenium Yeast on Dairy Cows in Parturition
Ren, Z., Bai, L.-P., Shen, L., Luo, Z., Zhou, Z., Zuo, Z., Ma, X., Deng, J., Wang, Y., Xu, S., et al. (2019) · Biological Trace Element Research · doi:10.1007/s12011-019-01999-7 · Cited by 8
Koška, J., Furtado, J. D., Hu, Y., Sinari, S. A., Budoff, M. J., Billheimer, D. D., Nedelkov, D., McClelland, R. L., & Reaven, P. D. (2022) · Journal of Lipid Research · doi:10.1016/j.jlr.2022.100263 · Cited by 8
Gonzalez, T. L., Schaub, A. M., Lee, B., Cui, J., Taylor, K. D., Dorfman, A. E., Goodarzi, M. O., Wang, E. T., Chen, Y.-D. I., Rotter, J. I., et al. (2022) · Fertility and Sterility · doi:10.1016/j.fertnstert.2022.11.010 · Cited by 8
Zebrafish Models to Study Ectopic Calcification and Calcium-Associated Pathologies
Santos, J. M. A., Laizé, V., Gavaia, P. J., Conceição, N., & Cancela, M. L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043366 · Cited by 8
Abbasi, D. A., Nguyen, T. T. A., Hall, D. A., Robertson-Dick, E. E., Berry‐Kravis, E., & Cologna, S. M. (2021) · The Cerebellum · doi:10.1007/s12311-021-01262-7 · Cited by 8
Kim, S. H., Park, W. Y., Kim, B., Kim, J.-H., Song, G., Park, J. Y., Jiao, W., Jung, S. J., Ahn, K. S., Kwak, H. J., et al. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108181 · Cited by 7
Çelik, M. Y., Canda, E. E., Yazıcı, H., Erdem, F., Yanbolu, A. Y., Altınok, Y. A., Parıltay, E., Akın, H., Uçar, S. K., & Çöker, M. (2024) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2024.02.006 · Cited by 7
Hypertriglyceridemia, a causal risk factor for atherosclerosis, and its laboratory assessment
Wieczorek, E., Ćwiklińska, A., & Jankowski, M. (2022) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2022-0189 · Cited by 7
Lipid-apolipoprotein interactions in amyloid fibril formation and relevance to atherosclerosis
Howlett, G. J., Ryan, T. M., & Griffin, M. D. W. (2018) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2018.08.010 · Cited by 7
Bullingham, O. M. N., Firkus, T. J., Goetz, F. W., Murphy, C. A., & Alderman, S. L. (2021) · Journal of Great Lakes Research · doi:10.1016/j.jglr.2021.11.005 · Cited by 7
Wei, X., Zhao, X., Shan, X., Zhu, Y., Wang, S., Chen, H., Li, H., & Ma, Y. (2022) · Genes · doi:10.3390/genes13081467 · Cited by 10
Novello, G., de Souza, F. F., & Canisso, I. F. (2024) · Animals · doi:10.3390/ani14142100 · Cited by 6
Induction of hyperlipidemic pancreatitis by different fatty acids: A narrative review
Wang, Y., Ge, P., & Chen, H. (2025) · World Journal of Gastroenterology · doi:10.3748/wjg.v31.i22.106575 · Cited by 8
Woods, M., McAlister, J. A., Segeren, L., da Silva, M. B., Deyarmin, J. S., Hakimi, A., Hermanson, D. J., Richter, J., Samra, S. N., & Geddes‐McAlister, J. (2025) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2025.101083 · Cited by 6
Al-Samawi, R. I., & Smaism, M. F. (2021) · Indian Heart Journal · doi:10.1016/j.ihj.2021.12.005 · Cited by 6
Hussein, A. A., & Mustafa, N. G. (2023) · Al-mağallaẗ al-ʻirāqiyyaẗ li-l-ʻulūm al-bayṭariyyaẗ/Iraqi journal of veterinary sciences · doi:10.33899/ijvs.2023.140070.3017 · Cited by 7
Severe hyperchylomicronemia in two infants with novel APOC2 gene mutation
Köse, E., Armağan, C., Kısa, P. T., Önay, H., & Arslan, N. (2018) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2018-0280 · Cited by 6
Ueda, M., Wolska, A. T., Burke, F. M., Escobar, M., Walters, L. L., Lalic, D., Hegele, R. A., Remaley, A. T., Rader, D. J., & Dunbar, R. L. (2020) · Case Reports in Endocrinology · doi:10.1155/2020/1865489 · Cited by 6
Self-citationZapatería, B., Sevillano, J., Sánchez‐Alonso, M. G., Limones, M., Pizarro‐Delgado, J., Zuccaro, A., Herradón, G., Medina‐Gómez, G., & Ramos, P. (2021) · The FASEB Journal · doi:10.1096/fj.202101181r · Cited by 6
Apolipoproteins in circulation: At the interface of thrombosis and stroke initiation
Etuzé, T., Vivien, D., & Dubois, F. (2025) · Progress in Lipid Research · doi:10.1016/j.plipres.2025.101343 · Cited by 6
Wieczorek, E., Ćwiklińska, A., Kuchta, A., Kortas‐Stempak, B., Gliwińska, A., & Jankowski, M. (2021) · Nutrients · doi:10.3390/nu13041224 · Cited by 5
Hyperlipidaemia: A Review of Literature
Lad, S. S., Kolhe, S. U., Devade, O. A., Patil, C. N., Nalawade, R. D., & Mansabdar, A. P. (2023) · Research Journal of Pharmacology and Pharmacodynamics · doi:10.52711/2321-5836.2023.00023 · Cited by 5
Lipoprotein Lipase Deficiency Arising in Type V Dyslipidemia
Tanaka, S., Ueno, T., Tsunemi, A., Nakamura, Y., Kobayashi, H. H., Hatanaka, Y., Haketa, A., Fukuda, N., Soma, M., & Abe, M. (2018) · Internal Medicine · doi:10.2169/internalmedicine.0952-18 · Cited by 5
Genetically Engineered Hamster Models of Dyslipidemia and Atherosclerosis
Xian, X., Wang, Y., & Liu, G. E. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-1924-7_26 · Cited by 6
Eruptive xanthomas in a patient with soft-drink diabetic ketosis and apolipoprotein E4/2
Tsuchiya, S., Sawada, S., Takeda, K., Takahashi, K. A., Nakajima, T., Kohata, M., Kurosawa, S., Satake, C., Imai, J., Kikuchi, K., et al. (2018) · Endocrine Journal · doi:10.1507/endocrj.ej18-0356 · Cited by 5
Bando, H., Taneda, S., & Manda, N. (2021) · JMA Journal · doi:10.31662/jmaj.2020-0104 · Cited by 5
Lipoprotein Metabolism and Cholesterol Balance
Acuña, M., & Cohen, D. E. (2020) · Wiley eBooks · doi:10.1002/9781119436812.ch22 · Cited by 5
Brasileiro-Martins, L. M., Cavalcante, S. A., Nascimento, T. P., Silva-Neto, A., Santos, M. D. M., Camillo-Andrade, A. C., Fischer, J. D. S. D. G., Ferreira, C., Oliveira, L. B., Sartim, M., et al. (2024) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0012072 · Cited by 4
Plasma proteomic profiles reveal immune modulation by immunonutrition in GI cancer
Santos, S. S., da Costa, L. A. T. J., Araripe, T. S. D. O., Reges, B. D. L. O., Ximenes, H. M. D. A., & Moreira, A. C. D. O. M. (2025) · Nutrition · doi:10.1016/j.nut.2025.113020 · Cited by 3
Inventive HDL Mimicking Nanoparticles: A Promising Frontier in Cardiovascular Disease Management
Ratra, S., Mukherjee, S., Ray, S., Yu, A., & Rengan, A. K. (2025) · Cardiovascular Toxicology · doi:10.1007/s12012-025-10074-8 · Cited by 4
Alireza, H. (2021) · International Journal of Membrane Science and Technology · doi:10.15379/2410-1869.2021.08.02.04 · Cited by 3
FISIOPATOLOGIA E TRATAMENTOS ATUALMENTE DISPONÍVEIS PARA DISLIPIDEMIA
Almeida, A. B., Pontes, B. B., Gioia, L. N., & Rangel, V. (2023) · EPITAYA eBooks · doi:10.47879/ed.ep.2023809p32 · Cited by 3
Shi, H., & Wang, Z. (2022) · Translational Pediatrics · doi:10.21037/tp-22-15 · Cited by 3
Quantitative Assays of Plasma Apolipoproteins
Poljak, A., Duncan, M. W., Jayasena, T., & Sachdev, P. S. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0471-7_3 · Cited by 3
Cholesterol transport in blood, lipoproteins, and cholesterol metabolism
Auley, M. T. M., & Morgan, A. E. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85857-1.00025-0 · Cited by 3
Saraceno, G. F., & Cione, E. (2025) · BioMedInformatics · doi:10.3390/biomedinformatics5010016 · Cited by 2
Liu, Y., Skudder‐Hill, L., Ko, J., Shamaitijiang, X., Sequeira, I. R., & Petrov, M. S. (2025) · Nutrients · doi:10.3390/nu17233718 · Cited by 2
Lipid dysregulation in chronic diseases: systems biology and omics perspectives
Majumder, D., Bhattacharya, D., Gill, H. S., Rajeev, M., Sharma, S., Dwivedi, S. P., Nag, M., & Lahiri, D. (2026) · Xenobiotica · doi:10.1080/00498254.2026.2680076 · Cited by 2
Cader, A., Stępniewska, J., & Różański, J. (2022) · Acta Biochimica Polonica · doi:10.18388/abp.2020_6462 · Cited by 2
Iheanacho, M. M., Analike, R. A., Meludu, S., Chukwuemeka, O. E., & Onah, C. E. (2022) · Discoveries · doi:10.15190/d.2022.18 · Cited by 4
Koška, J., Hu, Y., Furtado, J. D., Billheimer, D. D., Nedelkov, D., Allison, M., Budoff, M. J., McClelland, R. L., & Reaven, P. D. (2023) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2023.117214 · Cited by 2
Hyperlipidaemia: A Review of Literature
Lad, S. S., Kolhe, S. U., Devade, O. A., & Mansabdar, A. P. (2023) · Asian Journal of Pharmaceutical Research · doi:10.52711/2231-5691.2023.00033 · Cited by 2
Maravi, J. S. M., Leszczynski, E. C., Schwartz, C. S., Dev, P. K., Barber, J. L., Reasons, R. J., Pearce, R. W., McPhaul, M. J., Konrad, R. J., Robbins, J., et al. (2024) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2024.117587 · Cited by 2
Olano, C., Fariña, G., Wiszniewski, M., Medel, J., Morales, C. J., Friedman, S., Macri, E. V., Barchuk, M., Berg, G. A., Schreier, L. E., et al. (2025) · Journal of Lipid and Atherosclerosis · doi:10.12997/jla.2025.14.1.106 · Cited by 2
Gaudet, D. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-88286-6.00035-2 · Cited by 2
Signs in Disorders of Lipid Metabolism and Obesity
Manni, A., & Quarde, A. (2020) · Springer eBooks · doi:10.1007/978-3-030-49872-6_7 · Cited by 2
Molecular mechanisms of the cytoprotector cramizol effect in the experimental dyslipidemia model
Lizunov, A. V., Окуневич, И. В., Aa, L., Бычков, Э. Р., Piotrovskiy, L. B., & Shabanov, P. D. (2020) · Biomeditsinskaya Khimiya · doi:10.18097/pbmc20206604326 · Cited by 2
Vernardis, S. I., Demichev, V., Lemke, O., Grüning, N., Messner, C. B., White, M. E. H., Pietzner, M., Peluso, A., Collet, T., Henning, E., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1363070/v1 · Cited by 2
Hashim, A. A., Smaism, M. F., & Hassan, M. I. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns4.11114 · Cited by 1
Sequence Variant Analysis of the APOCII Locus among an Arab Cohort
Al‐Bustan, S. A., Alrashid, M. H., Al‐Serri, A., Annice, B. G., & Bahbahani, H. M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216293 · Cited by 1
Breschi, A., Wang, Y., Short, S. A., Luk, W., Erani, D. M., Kheradpour, P., Cimermančič, P., Tong, G. J., Martin, J. P., Liu, M., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-00964-x · Cited by 1
Lähteenmäki, E. I., Lehti, S., Jauhiainen, M., Kankaanpää, A., Soliymani, R., Baumann, M., Ruhanen, H., Käkelä, R., Vaara, J. P., Laakkonen, E. K., et al. (2025) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00130.2025 · Cited by 1
Han, H., Li, Q., Wang, C., Liang, Z., Zhang, L., Zhang, S., Tian, M., Li, S., Liu, D., Yang, G., et al. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.07.028 · Cited by 1
Evinacumab Improved the Homozygous Familial Hypercholesterolemia Lipid Metabolism: A Case Report
Matsuda, T., Osaki, Y., Matsumoto, N., Nakajima, R., Murayama, Y., Sugano, Y., IWASAKI, H. O., Mathis, B. J., Sekiya, M., & Shimano, H. (2025) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.65925 · Cited by 1
Wicks, T. R., Wolska, A. T., Ghazal, D., SHALAUROVA, I. Y., Weinstock-Guttman, B., Browne, R. W., Remaley, A. T., Zivadinov, R., & Ramanathan, M. K. (2026) · Antioxidants · doi:10.3390/antiox15010102 · Cited by 1
Self-citationCholesterol metabolism dysregulated by key HBV mutations revealed through multi-omics profiling
Chen, Y., Lin, P., Jin, J., Deng, M., & Wei, D. (2026) · iScience · doi:10.1016/j.isci.2026.115844 · Cited by 1
You, X., Wu, Z., Shi, L., Zheng, J., Pang, W., Zeng, W., Dong, W., & Zheng, Y. (2026) · Reproduction · doi:10.1093/reprod/xaag047 · Cited by 1
Mahdi, M. I., Abdulrahman, M. A., & Hameed, R. R. (2019) · Tikrit Journal of Pure Science · doi:10.25130/tjps.v24i6.430 · Cited by 1
Updated Clinical Guide to Exercise and Lipids
Mendoza, M. F., Kachur, S. M., & Lavie, C. J. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-88286-6.00015-7 · Cited by 1
Levels of Myostatin, Adiponectin and Lipid Profile in Hyperlipidemia Patients
Rashid, S. M., Alabbasy, R. H., & Abdulwahed, A. M. H. (2023) · Aalborg Academy Journal of Medical Sciences · doi:10.32441/ijms.6.3.3 · Cited by 1
Two Novel Mutations Associated with Familial Chylomicronemia in a Neonate
Jha, V. V., Arora, G., & Arora, V. (2024) · Newborn · doi:10.5005/jp-journals-11002-0105 · Cited by 1
Liu, Y., Ko, J., Skudder‐Hill, L., Shamaitijiang, X., Sequeira, I. R., & Petrov, M. S. (2025) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2025.104280 · Cited by 1
Molecular mechanisms of antiatherogenic drugs action
Lizunov, A. V., & Бычков, Э. Р. (2021) · Reviews on Clinical Pharmacology and Drug Therapy · doi:10.17816/rcf193291-301 · Cited by 1
Toyoshima, M. T. K. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2021.tde-11012022-135720 · Cited by 1
PhD, S. A. M., PhD, P. É. M., Töreki, E., Ifju, M., Barta, B. A., Szécsi, B., Losoncz, E., Dohy, Z., Barabás, J. I., Kosztin, A., et al. (2023) · Preprints.org · doi:10.20944/preprints202310.1359.v1 · Cited by 1
Wu, K. (2018) · Emirates Journal of Food and Agriculture · doi:10.9755/ejfa.2018.v30.i10.1827
Regulation of Lipoprotein Lipase Activity : an In-vitro Study of a Complex and Dynamic System
Kovrov, O. (2019) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Chen, J., Xiao, C. W., Wang, Y., Song, G., Wang, X., Liu, X., Chen, J., Lu, H., Kuai, J., Qin, X., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/680967
Transport and Carrier Proteins
Wang, C., & Li, Z. (2021) · Springer eBooks · doi:10.1007/978-981-16-1037-0_15
Dyslipidemia as Predictor of Missed Miscarriage
Оразмурадов, А. А., Morozov, S., Akhmatova, A. N., Haddad, K., Lopatin, A., Рамазанова, Ф. У., Викторовна, Б. И., Kyrtikov, S. I., Suleymanova, Z., & Lukaev, A. (2021) · International Journal of Biomedicine · doi:10.21103/article11(4)_oa4
Primär genetische Dyslipoproteinämien und Atheroskleroserisiko
Schwab, K. O., & Doerfer, J. (2022) · Springer eBooks · doi:10.1007/978-3-662-63320-5_3
Kadhim, A. M., Smaism, M. F., & Al-Hilli, N. M. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns6.12195
Crosstalk between hemostasis inhibitors and cholesterol biomarkers in multiple sclerosis
Parambi, R., Ziliotto, N., Bernardi, F., Baroni, M., Browne, R. W., Jakimovski, D., Weinstock‐Guttman, B., Zivadinov, R., & Ramanathan, M. K. (2022) · Bleeding Thrombosis and Vascular Biology · doi:10.4081/btvb.2022.41
Al-Turfi, Z. S. M. (2022) · International Journal of Drug Delivery Technology · doi:10.25258/ijddt.12.2.70
دراسة تأثير جذور وأوراق اللفت وخليطهما علي فرط الكوليسترول في فئران التجارب
صبح, ع., & شعلان, م. (1999) · Mağallaẗ Al-Iqtiṣād Al-Manzilī - Ǧāmiʿaẗ Al-Munūfiyyaẗ · doi:10.21608/mkas.2022.136490.1131
CARDIOLOGIA EM FOCO: PREVENÇÃO, DIAGNÓSTICO E TRATAMENTOS ATUAIS
Almeida, A. B., & Horevicht, C. M. (2023) · EPITAYA eBooks · doi:10.47879/ed.ep.2023809
Implications of stem cell–associated signals in pathogenesis of lipid disorders
Kumaran, K., Devadarshini, P., Loganathbabu, V. K. T., Nidhu, A. B., Shriya, P., Hemarangan, J., Murali, R. M. V., & Jothi, K. N. A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18800-8.00023-x
Щастный, А. Т., Осочук, А. С., Martsinkevich, A. F., & Стефанович, О. С. (2023) · Лабораторная диагностика Восточная Европа · doi:10.34883/pi.2023.12.3.015
Rocha, A. J. S., Gomes, F. M. D. S., Freire, J. A. P., & Calou, I. B. F. (2023) · Journal Archives of Health · doi:10.46919/archv4n4-014
Therapies in Disorders of Lipid Metabolism and Obesity
Akuffo Quarde, M. D. (2023) · Wiley eBooks · doi:10.1002/9781119863564.ch7
Székely, A. D., Pállinger, É., Töreki, E., Ifju, M., Barta, B. A., Szécsi, B., Losoncz, E., Dohy, Z., Barabás, J. I., Kosztin, A., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031752
Metadata
- Authors
- Wolska, A., Dunbar, R. L., Freeman, L. A., Ueda, M., Amar, M. J., Sviridov, D. O., & Remaley, A. T.
- Affiliations
- National Institutes of Health (US)
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
- Corresponding author
- Wolska, Anna
- Venue
- Atherosclerosis
- Publisher
- Elsevier BV
- Published
- 2017-12
- Volume
- 267
- Pages
- 49-60
- ISSN
- 0021-9150 (ISSN-L)
- PMC
- PMC5705268
- OpenAlex
- W2767128978
- Cited by
- 231
- References
- 125
- Citations by year
- 2026: 18 · 2025: 28 · 2024: 20 · 2023: 35 · 2022: 34 · 2021: 44 · 2020: 25 · 2019: 15 · 2018: 11
- FWCI
- 1.97
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Atherosclerosis (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute (ZIAHL006095)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Keywords
- apolipoprotein C-II, triglyceride metabolism, triglyceride-rich lipoproteins, chylomicrons, VLDL, high-density lipoprotein, hypertriglyceridemia, transcriptional regulation, treatment options
- MeSH terms
- Animals, Chylomicrons, Gene Expression Regulation, Multigene Family, Humans, Hydrolysis, Intestinal Mucosa, Lipolysis, Lipoprotein Lipase, Lipoproteins, Lipoproteins, HDL, Lipoproteins, VLDL, Liver, Macrophages, Mutation, Transcription, Genetic, Triglycerides, Mice, Rats, Apolipoprotein C-II
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review