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Cited by 174Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic ControlCardiovascular and exercise physiology

The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.

Exercise and non-pharmacological treatment of POTS

Open access
Fu, Qi, Levine, Benjamin D.·2018·Autonomic Neuroscience
DOI 10.1016/j.autneu.2018.07.001PMC PMC6289756
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Abstract

Recent research has demonstrated that cardiovascular deconditioning (i.e., cardiac atrophy and hypovolemia) contributes significantly to the Postural Orthostatic Tachycardia Syndrome (POTS) and its functional disability. Therefore, physical reconditioning with exercise training and volume expansion via increased salt and fluid intake should be initiated early in the course of treatment for patients with POTS if possible. The use of horizontal exercise (e.g., rowing, swimming, recumbent bike, etc.) at the beginning is a critical strategy, allowing patients to exercise while avoiding the upright posture that elicits their POTS symptoms. As patients become increasingly fit, the duration and intensity of exercise should be progressively increased, and upright exercise can be gradually added as tolerated. Supervised training is preferable to maximize functional capacity. Other non-pharmacological interventions, which include: 1) chronic volume expansion via sleeping in the head-up position; 2) reduction in venous pooling during orthostasis by lower body compression garments extending at least to the xiphoid or with an abdominal binder; and 3) physical countermeasure maneuvers, such as squeezing a rubber ball, leg crossing, muscle pumping, squatting, negative-pressure breathing, etc., may also be effective in preventing orthostatic intolerance and managing acute clinical symptoms in POTS patients. However, randomized clinical trials are needed to evaluate the efficacies of these no…

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Research works printed but not linked: 2

  1. Dorfman, 2007, Cardiac atrophy in women following bed rest, J. Appl. Physiol., 103, 8, 10.1152/japplphysiol.01162.2006 · DOI · Paper page
  2. Shibata, 2010, Supine cycling plus volume loading prevent cardiovascular deconditioning during bed rest, J. Appl. Physiol., 108, 1177, 10.1152/japplphysiol.01408.2009 · DOI

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Metadata

Authors
Fu, Q., & Levine, B. D.
Affiliations
Texas Health Dallas (US)
Corresponding author
Fu, Qi
ORCID
Venue
Autonomic Neuroscience
Publisher
Elsevier BV
Published
2018-12
Volume
215
Pages
20-27
ISSN
1566-0702 (ISSN-L)
DOI
10.1016/j.autneu.2018.07.001
PMC
PMC6289756
OpenAlex
W2810136578
Cited by
174
References
88
Citations by year
2026: 24 · 2025: 25 · 2024: 32 · 2023: 23 · 2022: 31 · 2021: 15 · 2020: 14 · 2019: 7 · 2018: 2
FWCI
2.11
Type
journal article
Language
en
Open access
Licence
Locations
  • Autonomic Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institutes of Health (K23 HL075238)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords
postural orthostatic tachycardia syndrome, exercise training, cardiovascular deconditioning, cardiac atrophy, hypovolemia, volume expansion, supervised exercise, orthostatic intolerance, non-pharmacological treatment
MeSH terms
Exercise Therapy, Humans, Postural Orthostatic Tachycardia Syndrome

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