Cited by 182Systemic Lupus Erythematosus ResearchReproductive System and PregnancyPregnancy and preeclampsia studies

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: Data from a European multicenter retrospective study

Mekinian, Arsène, Lazzaroni, Maria Grazia, Kuzenko, Anna, Alijotas-Reig, Jaume, Ruffatti, Amelia, Levy, Pierre, Canti, Valentina, Bremme, Katarina, Bezanahary, Holy, Bertero, Tiziana, Dhote, Robin, Maurier, Francois, Andreoli, Laura, Benbara, Amélie, Tigazin, Ahmed, Carbillon, Lionel, Nicaise-Roland, Pascale, Tincani, Angela, Fain, Olivier·2015·Autoimmunity Reviews

DOI 10.1016/j.autrev.2015.01.012

Open this paper in CoChat — free account

Abstract

In European multicenter study, we aimed to describe the real-life hydroxychloroquine use in APS patients during pregnancy and determine its benefit in refractory obstetrical APS. We analyzed the outcome of pregnancies treated by hydroxychloroquine in patients with APS or asymptomatic antiphospholipid (aPL) antibodies carriers. Thirty patients with APS with 35 pregnancies treated by hydroxychloroquine were analyzed. Comparing the outcome of pregnancies treated by the addition of hydroxychloroquine to previous pregnancies under the conventional treatment, pregnancy losses decreased from 81% to 19% (p<0.05), without differences in the associated treatments. The univariate analysis showed that the previous intrauterine deaths and higher hydroxychloroquine amount (400mg per day) were the factors associated with pregnancy outcome. Considering 14 patients with previous refractory obstetrical APS (n=5 with obstetrical and thrombotic primary APS and n=9 with purely obstetrical APS), all with previous pregnancy losses under treatment (aspirin with LMWH in 11 cases and LMWH in 3 cases), the addition of hydroxychloroquine resulted in live born babies in 11/14 (78%) cases (p<0.05). Our study shows the benefit of hydroxychloroquine addition in patients with refractory obstetrical APS and raises the need of prospective studies to confirm our preliminary study.

Integrity signals

Registry

Crossref · 10.1016/j.autrev.2015.01.012

Cites

22 of 22 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
MIYAKIS, S., LOCKSHIN, M. D., ATSUMI, T., BRANCH, D. W., BREY, R. L., CERVERA, R., DERKSEN, R. H. W. M., DE GROOT, P. G., KOIKE, T., MERONI, P. L., et al. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.01753.x · Cited by 7,203
Self-citation
Antiphospholipid syndrome
Ruiz‐Irastorza, G., Crowther, M. A., Branch, W. D., & Khamashta, M. A. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60709-x · Cited by 875
Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies
Lockshin, M. D., Kim, M., Laskin, C. A., Guerra, M., Branch, D. W., Merrill, J., Petri, M., Porter, T. F., Sammaritano, L., Stephenson, M. D., et al. (2012) · Arthritis & Rheumatism · doi:10.1002/art.34402 · Cited by 388
14th International Congress on Antiphospholipid Antibodies Task Force Report on Antiphospholipid Syndrome Treatment Trends
Erkan, D., Aguiar, C. L., ANDRADE, D. C. O. D., Cohen, H., Cuadrado, M. J., Danowski, A., Levy, R. A., Ortel, T. L., Rahman, A., Salmon, J. E., et al. (2014) · Autoimmunity Reviews · doi:10.1016/j.autrev.2014.01.053 · Cited by 322
The European Registry on Obstetric Antiphospholipid Syndrome (EUROAPS): A survey of 1000 consecutive cases
Alijotas‐Reig, J., Esteve‐Valverde, E., Ferrer‐Oliveras, R., Comet, L. S., Lefkou, E. E., MEKINIAN, A., Belizna, C. C., Ruffatti, A., Tincani, A., Marozio, L., et al. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2018.12.006 · Cited by 220
Self-citation
Risk factors for pregnancy failure in patients with anti-phospholipid syndrome treated with conventional therapies: a multicentre, case-control study
Ruffatti, A., Tonello, M., Visentin, M. S., Bontadi, A., Hoxha, A., Carolis, S. D., Botta, A., Salvi, S., Nuzzo, M. D., Rovere, P. Q., et al. (2011) · Rheumatology · doi:10.1093/rheumatology/ker139 · Cited by 214
Self-citation
Pregnancy outcome in different clinical phenotypes of antiphospholipid syndrome
Bramham, K., Hunt, B., Germain, S., Calatayud, I., Khamashta, M., Bewley, S., & Nelson-Piercy, C. (2010) · Lupus · doi:10.1177/0961203309347794 · Cited by 185
First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss
Bramham, K., Thomas, M., Nelson-Piercy, C., Khamashta, M., & Hunt, B. J. (2011) · Blood · doi:10.1182/blood-2011-02-339234 · Cited by 180
The European Registry on Obstetric Antiphospholipid Syndrome (EUROAPS): A survey of 247 consecutive cases
Alijotas‐Reig, J., Ferrer‐Oliveras, R., Ruffatti, A., Tincani, A., Lefkou, E. E., Bertero, M. T., Coloma, E., Carolis, S. D., Espinosa, G., Rovere, P. Q., et al. (2014) · Autoimmunity Reviews · doi:10.1016/j.autrev.2014.12.010 · Cited by 152
Self-citation
Antithrombotic effects of hydroxychloroquine in primary antiphospholipid syndrome patients
Schmidt‐Tanguy, A., Voswinkel, J., Henrion, D., Subra, J. F., Loufrani, L., Rohmer, V., Ifrah, N., & Belizna, C. (2013) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12363 · Cited by 132

Flagged first, then by citations

Show all 22 references

Sorted by citations

Items 101–181 of 181

Long Term Follow up of Patients With Primary Obstetric Antiphospholipid Syndrome
Niznik, S., Rapoport, M. J., Avnery, O. H., Lubetsky, A., Shavit, R., Ellis, M. H., & Agmon‐Levin, N. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.824775 · Cited by 11
ANA-positive versus ANA-negative Antiphospholipid Antibody-positive Patients: Results from the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Clinical Database and Repository (“Registry”)
Cecchi, I., Radin, M., Foddai, S. G., Barinotti, A., ANDRADE, D. C. O. D., Tektonidou, M. G., Pengo, V., Ruiz‐Irastorza, G., Belmont, M. H., López-Pedrera, C., et al. (2024) · Rheumatology · doi:10.1093/rheumatology/keae583 · Cited by 11
Pregnancies in women receiving renal transplant for lupus nephritis: description of nine pregnancies and review of the literature
Campise, M., Giglio, E., Trespìdi, L., Messa, P., & Moroni, G. L. (2015) · Lupus · doi:10.1177/0961203315583542 · Cited by 11
Lupus nephritis and pregnancy outcome
Schreiber, K. I., Stach, K., & Sciascia, S. (2017) · Autoimmunity Reviews · doi:10.1016/j.autrev.2017.02.001 · Cited by 11
Hydroxychloroquine in systemic lupus erythematosus, anti-SSA/SSB, and antiphospholipid antibody-positive pregnancies
Saleh, Z., Somers, E. C., Romero, V., & Marder, W. (2025) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.09.002 · Cited by 11
Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a N ω-nitro-l-arginine methyl ester-induced preeclampsia rat model
Choi, M., Hwang, J. R., Sung, J., Byun, N., Seok, Y. S., Cho, G. J., Choi, S., Kim, J.-S., Oh, S., & Roh, C. (2022) · Journal of Hypertension · doi:10.1097/hjh.0000000000003279 · Cited by 10
Do adverse pregnancy outcomes contribute to accelerated cardiovascular events seen in young women with systemic lupus erythematosus?
Soh, M. C., Nelson‐Piercy, C., Westgren, M., McCowan, L. M. E., & Pasupathy, D. (2017) · Lupus · doi:10.1177/0961203317719146 · Cited by 11
Nonbacterial thrombotic endocarditis in a patient with primary antiphospholipid syndrome
Sirinvaravong, N., Ziccardi, M. C. R., Patnaik, S., Shah, M. K., Fernandez, G., Aliling, J.-N., & Rubin, A. (2018) · Oxford Medical Case Reports · doi:10.1093/omcr/omy024 · Cited by 10
Recomendaciones de la Sociedad Española de Reumatología sobre síndrome antifosfolípido primario. Parte II: síndrome antifosfolípido obstétrico y situaciones especiales
Cáliz, R., Fontecha, P. D. D. C., Galindo-Izquierdo, M., Longo, F. J. L., Zamora, M. Á. M., Santamaría, A., Pliego, O. A., Lozano, M. J. C., Beltrán, M. P. D., Ortells, L. C., et al. (2019) · Reumatología Clínica · doi:10.1016/j.reuma.2018.11.004 · Cited by 10
Risk factors of first thrombosis in obstetric antiphospholipid syndrome
Luo, L., Cai, Q., Liu, X., Hou, Y., & Li, C. (2024) · Lupus Science & Medicine · doi:10.1136/lupus-2023-001044 · Cited by 9
Beyond current concepts in anti-phospholipid syndrome: The 16th International Congress on Anti-phospholipid Antibodies (ICAPA) in Manchester
Chighizola, C. B., Sciascia, S., Andréoli, L., & Meroni, P. L. (2020) · Autoimmunity Reviews · doi:10.1016/j.autrev.2020.102615 · Cited by 9
The clinical significance of antiphospholipid antibodies in COVID-19 infection
Atalar, E., Erden, A., Güven, S. C., Armağan, B., Ateş, İ., Küçükşahin, O., & Omma, A. (2022) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.15423 · Cited by 9
Fausses couches précoces récurrentes inexpliquées : quelle est la place de l’immunomodulation ?
MEKINIAN, A., Cohen, J., Kayem, G., Carbillon, L., Nicaise‐Roland, P., Gaugler, B., Daraï, É., Bornes, M., & Fain, O. (2016) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2016.08.001 · Cited by 9
Self-citation
Preeclampsia before fetal viability in women with primary antiphospholipid syndrome- materno-fetal outcomes in a series of 7 cases
Mayer-Pickel, K. I., Stern, C., Cervar-Zivkovic, M., Schöll, W., & Moertl, M. G. (2020) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2020.103101 · Cited by 8
New and upcoming treatments in antiphospholipid syndrome: A comprehensive review
Signorelli, F., Balbi, G. G. M., Domingues, V., & Levy, R. A. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.04.012 · Cited by 8
Use of synthetic and biologic DMARDs during pregnancy
Balbi, G., Domingues, V., Balbi, G., de Jésus, G. D., & Levy, R. (2019) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2019.1541739 · Cited by 6
Obstetric antiphospholipid syndrome
de Barros, V. I. P. V. L., Igai, A. M. K., de Oliveira, A. L. M. L., Teruchkin, M. M., & Orsi, F. A. (2021) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0041-1732382 · Cited by 6
Hydroxychloroquine and antiphospholipid antibody-related pregnancy morbidity: a systematic review and meta-analysis
Frishman, M., Radin, M., & Schreiber, K. I. (2020) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000649 · Cited by 7
Non-Criteria Obstetric Antiphospholipid Syndrome: Myth or Reality?
Beça, S., Borrell, M., Cervera, R., Figueras, F., Nadal, A., Espinosa, G., & Baños, N. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14041299 · Cited by 6
Seronegative Obstetric Antiphospholipid Syndrome Finally Treated Successfully
Alghanim, K. K., Alrayes, H. A., & Aljurbua, R. M. (2022) · European Journal of Case Reports in Internal Medicine · doi:10.12890/2022_003686 · Cited by 5
Hepatic infarction in a pregnant woman with antiphospholipid syndrome and triple antibody positivity: A case report focusing on catastrophic antiphospholipid syndrome
Kim, J.-H., Yee, C., Kuk, J.-Y., Choi, S., Oh, S., Roh, C., & Kim, J.-H. (2016) · Obstetrics & Gynecology Science · doi:10.5468/ogs.2016.59.5.397 · Cited by 5
Embarazo y enfermedades autoinmunitarias
Alijotas‐Reig, J., & Esteve‐Valverde, E. (2016) · Medicina Clínica · doi:10.1016/j.medcli.2016.11.008 · Cited by 5
Self-citation
The antiphospholipid syndrome
Barilaro, G., Espinosa, G., & Cervera, R. (2021) · Revista Colombiana de Reumatología · doi:10.1016/j.rcreu.2021.03.012 · Cited by 7
Pregnancy and the Autoimmune Patient
Mills, B. S., & Bermas, B. L. (2024) · Current Allergy and Asthma Reports · doi:10.1007/s11882-024-01143-z · Cited by 4
Autophagy in PE : Dispute, Role and Potential Target
Xu, M., Wang, Q., Wang, F., Li, K., Ma, H., Li, M., Hao, Z., Li, Z., Liu, J., Huang, X., et al. (2025) · Cell Proliferation · doi:10.1111/cpr.70102 · Cited by 5
Recommendations of the Spanish Rheumatology Society for primary antiphospholipid syndrome. Part II: Obstetric antiphospholipid syndrome and special situations
Cáliz, R., Fontecha, P. D. D. C., Galindo-Izquierdo, M., Longo, F. J. L., Zamora, M. Á. M., Santamaría, A., Pliego, O. A., Lozano, M. J. C., Beltrán, M. P. D., Ortells, L. C., et al. (2019) · Reumatología Clínica (English Edition) · doi:10.1016/j.reumae.2018.11.013 · Cited by 4
Response to: 'Correspondence on 'EULAR recommendations for the management of antiphospholipid syndrome in adults' by Zhou et al
Tektonidou, M. G., Tincani, A., & Ward, M. M. (2020) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2020-219048 · Cited by 4
Self-citation
Idiopathic Normal Pressure Hydrocephalus – What We Know
Baltatanu, D., & Berteanu, M. (2019) · MAEDICA – a Journal of Clinical Medicine · doi:10.26574/maedica.2019.14.2.161 · Cited by 4
Response to: ‘Correspondence on ‘EULAR recommendations for the management of antiphospholipid syndrome in adults’’ by Gao and Qin
Tektonidou, M. G., Tincani, A., & Ward, M. M. (2021) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2021-220116 · Cited by 4
Self-citation
Placental lesions in patients with antiphospholipid antibody syndrome: experience of a single tertiary-care Italian reference center
Canti, V., LORENZO, R. D., Inguscio, G., Girardelli, S., Pozzoni, M., Tenace, N. P., Lucianò, R., Pasi, F., Castiglioni, M. T., Cavoretto, P. I., et al. (2024) · Frontiers in Lupus · doi:10.3389/flupu.2024.1459172 · Cited by 3
Self-citation
Mechanism of hydroxychloroquine in the treatment of obstetric antiphospholipid syndrome by inhibiting NETs-induced trophoblast pyroptosis
Liu, J., Xu, M., Shen, D., & Wang, X. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10765-z · Cited by 3
Treatment of Systemic Lupus Erythematosus
Bertsias, G. K., Fanouriakis, A., & Boumpas, D. T. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-31696-5.00081-4 · Cited by 3
Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine
Zhao, J., Zhao, Z., Hou, W., Jiang, Y., Liu, G., Ren, X., Liu, K., Liu, H., Chen, K., & Huang, H. (2022) · Molecules · doi:10.3390/molecules27165175 · Cited by 3
Pregnancy planning in lupus and APS patients
Haase, I., & Fischer‐Betz, R. (2024) · Frontiers in Lupus · doi:10.3389/flupu.2024.1479881 · Cited by 3
Antiphospholipid Syndrome
Siddique, F., Patel, D. P., & Roberts, W. N. (2016) · Compendium of Inflammatory Diseases · doi:10.1007/978-3-7643-8550-7_161 · Cited by 3
Mechanisms and roles of hydroxychloroquine in pregnancy in rheumatic diseases
Kong, L., Wang, Q., He, Y., & Zhang, W. (2025) · Annals of the Academy of Medicine Singapore · doi:10.47102/annals-acadmedsg.2023262 · Cited by 2
B Cell Tolerance and Obstetric Antiphospholipid Syndrome
Laht, B., Timilsina, S., Gershwin, M. E., & Uibo, R. (2025) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-025-09064-z · Cited by 2
[Obstetric Antiphospholipid Syndrome: Insights on the Diagnosis, Treatment, and Hot Issues].
Gao, R., & Qin, L. (2024) · 四川大学学报：医学版 · doi:10.12182/20240560104 · Cited by 2
Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution
Gao, R., Qing, P., Chen, H., Hu, Z., Yang, Q., Lu, C., Liu, H., Zeng, R., Tang, Y., Yu, F. D., et al. (2025) · Advanced Science · doi:10.1002/advs.202503480 · Cited by 4
Le syndrome des antiphospholipides obstétrical : quelle est la place d’un traitement complémentaire à la combinaison aspirine et héparine ?
MEKINIAN, A., Kayem, G., Cohen, J., Carbillon, L., Abisror, N., JOSSELIN-MAHR, L., Bornes, M., & Fain, O. (2017) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2016.12.010 · Cited by 2
Self-citation
Utilisation de l’hydroxychloroquine et de la prednisone en présence d’une auto-immunité sérique dans l’infertilité féminine
Cheloufi, M., Wackenheim, C., Dumestre‐Pérard, C., Gueniffey, A., Equy, V., Thong-Vanh, C., Dunand-Faure, C., Hoffmann, P., & Deroux, A. (2018) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2017.12.008 · Cited by 2
Complications obstétricales du lupus érythémateux systémique et du SAPL : une prise en charge multidisciplinaire
Mattuizzi, A., Madar, H., Froeliger, A., Houssin, C., Chabanier, P., Merlot, B., Lazaro, E., Elleboode, B., & Sentilhes, L. (2020) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2020.03.005 · Cited by 2
Síndrome antifosfolipídico obstétrico
(2021) · Revista Uruguaya de Medicina Interna · doi:10.26445/06.02.5 · Cited by 2
Using hydroxychloroquine and protecting the retina
Schreiber, K. I., Davies, N., & Hunt, B. J. (2018) · Lupus · doi:10.1177/0961203318777113 · Cited by 2
Antiphospholipid Syndrome
Siddique, F., Patel, D. P., & Roberts, W. N. (2015) · Encyclopedia of Inflammatory Diseases · doi:10.1007/978-3-0348-0620-6_161-6 · Cited by 2
Utilisation de l’hydroxychloroquine dans les pathologies obstétricales récurrentes à médiation immune (en dehors du lupus systémique) : fondements et preuves scientifiques
Dernoncourt, A., Salle, V., Cheloufi, M., Kayem, G., & MEKINIAN, A. (2024) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2024.12.004 · Cited by 1
Self-citation
Hydroxychloroquine can reduce fetal growth restriction in a dexamethasone-induced rat model
Choi, M., Hwang, J. R., Sung, J., Choi, S., Kim, J.-S., Roh, C., & Oh, S. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118084 · Cited by 1
Use of plasmapheresis in treatment of patients with unfavorable anamnestic pregnancy outcomes coupled to antiphospholipid antibodies
Еремеева, Д. Р., Зайнулина, М. С., Dolgova, Y. S., Шахалиев, Р. А., Сильванович, О. А., & Pavlova, L. A. (2021) · Obstetrics Gynecology and Reproduction · doi:10.17749/2313-7347/ob.gyn.rep.2021.105 · Cited by 1
Сase of neonatal lupus in one of two children of dichorial diamniotic pregnancy in a woman with unrecognized systemic lupus erythematosus and lupus nephritis
Kirsanova, T., Kravchenko, N., & Балакирева, А. И. (2020) · Nephrology (Saint-Petersburg) · doi:10.36485/1561-6274-2020-24-2-88-95 · Cited by 1
Treatments and new perspectives of Antiphospholipid Syndrome in pregnancy
Delorenzi, J. C. B., Cunha, M. R., Vergara, G. A., & Mary, C. S. S. (2018) · Medical Research Archives · doi:10.18103/mra.v6i5.1783 · Cited by 1
Preconception Obstetrics and Rheumatology Consultation: A Protective Factor Against Spontaneous Abortion in Women With Autoimmune Rheumatic Disorders.
Javinani, A., Radmard, F., Razavinia, F. S., & Masoumi, M. (2022) · PubMed · doi:10.1097/rhu.0000000000001667
The Impact of aPL Detection on Pregnancy
Bertero, M. T., Kuzenko, A., & Bazzan, M. (2016) · Rare diseases of the immune system · doi:10.1007/978-3-319-24535-5_13
Self-citation
Treatment of Pregnancy Complications in Antiphospholipid Syndrome
Nassar, A. H., Uthman, I. W., Eid, J., & Khamashta, M. A. (2016) · Technical report · doi:10.1016/b978-0-444-63655-3.00018-1
Antiphospholipid Antibodies and Reproduction
Sammaritano, L. R. (2017) · Cambridge University Press eBooks · doi:10.1017/9781139976787.012
Pregnancy and autoimmune diseases
Alijotas‐Reig, J., & Esteve‐Valverde, E. (2017) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2017.02.022
Self-citation
Estudo randomizado e duplo cego com uso de difosfato de cloroquina para a manuntenção de remissão da hepatite autoimune apos a suspensão da imunossupressão
Terrabuio, D. R. B. (2018) · doi:10.11606/t.5.2018.tde-01082018-132532
Would Hydroxychloroquine Be A New Promising Drug in Managing Antiphospholipid Syndrome?
Mohsen, A. (2018) · Drug Designing & Intellectual Properties International Journal · doi:10.32474/ddipij.2018.02.000141
The Antiphospholipid Syndrome
Rand, J. H., & Wolgast, L. R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35762-3.00141-4
Management of antiphospholipid syndrome in adults: The European League Against Rheumatism (EULAR) recommendations
Veselinović, M., Lucic, A. T., Jakovljevic, V. L., & Aničić, A. (2019) · Medicinski casopis · doi:10.5937/mckg53-23292
A bridge over troubled waters: Anti-inflammatory therapy for patients with refractory obstetric antiphospholipid syndrome?
Schreiber, K. I., Piazza, G., & Hunt, B. J. (2021) · Thrombosis Research · doi:10.1016/j.thromres.2021.09.003
Rheumatological Diseases
de Jesús, N. R., Lacerda, M. I., dos Santos, F. C., Levy, R. A., & de Jesús, G. R. (2021) · Springer eBooks · doi:10.1007/978-3-030-83434-0_28
Obstetric Antiphospholipid Syndrome
Hoxha, A., & Simioni, P. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.101804
Rheumatic diseases and reproductive outcomes
Mills, B. S., & Bermas, B. L. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90805-4.00006-7
B-cell pathology and repeated implantation failures
Bao, S., Du, M., & Wang, X. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90805-4.00022-5
Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome
Takaki, Y., Daimon, A., Nunode, M., Tanaka, T., Fujita, D., & Ohmichi, M. (2022) · Case Reports in Obstetrics and Gynecology · doi:10.1155/2022/5612091
Outcomes and Influencing Factors of 126 Pregnancy Patients with Undifferentiated Connective Tissue Disease: A Real-world Prospective StudyPreprint
Li, S., Zhao, Y., Sun, Z., Guo, Y., Deng, X., Liu, Y., Zhang, T., & Shu, Q. (2022) · Research Square · doi:10.21203/rs.3.rs-2070032/v1
Rheumatologische Krankheiten und Schwangerschaft: Systemischer Lupus erythematodes, Antiphospholipidsyndrom, rheumatoide Arthritis, Spondyloarthritis, systemische Sklerose, entzündliche Myopathien und Vaskulitis
Förger, F., & Mayer-Pickel, K. I. (2022) · Springer Reference Medizin · doi:10.1007/978-3-662-44369-9_72-1
L'hydroxychloroquine en 2023 : le point
Lioté, F., & Léger, B. (2023) · Elsevier eBooks · doi:10.1016/b978-2-294-78249-7.00018-7
Hydroxychloroquine as a potential therapy for ANCA-associated vasculitis
Jain, S., Sangle, S. R., Kim, S., John, S., & D’Cruz, D. P. (2024) · Vessel Plus · doi:10.20517/2574-1209.2023.142
Acute peripartum pancreatitis complicating seronegative antiphospholipid antibody syndrome in pregnancy
Zimmer, Z., Hill, R., Fratto, V. M., & Lutgendorf, M. A. (2024) · BMJ Case Reports · doi:10.1136/bcr-2022-250664
Rheumatologische Krankheiten und Schwangerschaft: Systemischer Lupus erythematodes, Antiphospholipidsyndrom, rheumatoide Arthritis, Spondyloarthritis, systemische Sklerose, entzündliche Myopathien und Vaskulitis
Förger, F., & Mayer-Pickel, K. I. (2024) · Springer Reference Medizin · doi:10.1007/978-3-662-63506-3_72
Obstetric and Neonatal Outcomes among Patients with Obstetric Antiphospholipid Antibody Syndrome: A Prospective Observational Study Comparing Patients Receiving Conventional Therapy (LMWH + Aspirin) and Patients Receiving Additional Hydroxychloroquine
Madhva Prasad, S., Vishnupriya, K., Giliyar, S., Sharma, M. S., & Bellarmin, L. S. (2025) · Journal of South Asian Federation of Obstetrics and Gynaecology · doi:10.5005/jp-journals-10006-2690
Immunologie de la fécondation, de l’implantation et de la grossesse : Interactions clés et perspectives thérapeutiques
Cheloufi, M., Abisror, N., Dernoncourt, A., MEKINIAN, A., & Kayem, G. (2025) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2025.11.005
Self-citation
The impact of anti-phosphatidylserine/prothrombin antibodies on pregnancy outcomes in patients with unexplained recurrent implantation failure: a retrospective cohort study
Han, D., Zhou, J., Shi, J., Yang, N., Liu, Q., Zhang, J., Wang, H., Wang, Y., & Zhao, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1731905
Effect of hydroxychloroquine on pregnancy outcomes in women with unexplained recurrent pregnancy loss complicated with antinuclear antibody positivity: a multicentre prospective cohort study protocol
Ma, B., Han, Y., Tian, T., Zeng, L., Chen, L., Yuan, Z., Hao, G., Li, Y., Wang, H., & Li, L. (2026) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-026-08923-7
Management of patients with antiphospholipid antibodies or antiphospholipid syndrome during pregnancy
Mills, B. S., & Bermas, B. L. (2026) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000001152
The impact of antinuclear antibodies and complement levels in the prognosis of pregnant women within the antiphospholipid syndrome spectrum
Bravo, S. G., Martínez-Taboada, V. M., Barrio-Longarela, S. D., Merino, A., Comins‐Boo, A., López‐Hoyos, M., & Hernández, J. L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1818605
Antiphospholipid Syndrome and Pregnancy
Zucchi, D., Ciribè, B., Tani, C., & Mosca, M. (2026) · Springer eBooks · doi:10.1007/978-981-95-9581-5_8
Preconceptional Counseling and Assessments in Autoimmune Rheumatic Diseases
Santos, C. S., Dyball, S., de Jesús, G. R., Rom, A. L., Sánchez, N. M., Moore, L., Pimentel, G., & Andréoli, L. (2026) · Springer eBooks · doi:10.1007/978-981-95-9581-5_5
Rheumatological Diseases: Systemic Lupus Erythematosus, Antiphospholipid Syndrome, Rheumatoid Arthritis, Spondyloarthritis, Systemic Sclerosis, Inflammatory Myopathies and Vasculitis
Förger, F., & Mayer-Pickel, K. I. (2026) · Springer eBooks · doi:10.1007/978-3-662-70578-0_35
Síndrome antifosfolípide obstétrica Número 6 – Junho 2021
de Barros, V. I. P. V. L., Igai, A. M. K., de Oliveira, A. L. M. L., Teruchkin, M. M., & Orsi, F. A. (2021) · Femina · doi:10.61622/0100-7254496202106

Authors: Mekinian, A., Lazzaroni, M. G., Kuzenko, A., Alijotas-Reig, J., Ruffatti, A., Levy, P., Canti, V., Bremme, K., Bezanahary, H., Bertero, T., Dhote, R., Maurier, F., Andreoli, L., Benbara, A., Tigazin, A., Carbillon, L., Nicaise-Roland, P., Tincani, A., & Fain, O.
Affiliations: Assistance Publique – Hôpitaux de Paris (FR)
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
A. O. Ordine Mauriziano di Torino (IT)
University of Padua (IT)
IRCCS Ospedale San Raffaele (IT)
Karolinska Institutet (SE)
Université Sorbonne Paris Nord (FR)
ORCID: Mekinian, Arsène
Lazzaroni, Maria Grazia
Ruffatti, Amelia
Canti, Valentina
Maurier, Francois
Benbara, Amélie
Carbillon, Lionel
Fain, Olivier
Venue: Autoimmunity Reviews
Publisher: Elsevier BV
Published: 2015-06
Volume: 14
Issue: 6
Pages: 498-502
ISSN: 1568-9972 (ISSN-L)
DOI: 10.1016/j.autrev.2015.01.012
OpenAlex: W1966792319
Cited by: 182
References: 22
Citations by year: 2026: 7 · 2025: 11 · 2024: 13 · 2023: 8 · 2022: 16 · 2021: 14 · 2020: 23 · 2019: 21 · 2018: 24 · 2017: 14 · 2016: 20 · 2015: 11
FWCI: 19.30
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Autoimmunity Reviews (publishedVersion)
PubMed (publishedVersion)
Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
Padua Research Archive (University of Padova) (submittedVersion)
Topics: Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
Keywords: hydroxychloroquine, antiphospholipid syndrome, pregnancy outcomes, miscarriage, antiphospholipid antibodies, low molecular weight heparin, aspirin, live birth, intrauterine fetal death
MeSH terms: Female, Humans, Hydroxychloroquine, Pregnancy, Pregnancy Outcome, Retrospective Studies, Multicenter Studies as Topic, Antiphospholipid Syndrome, Antibodies, Antiphospholipid

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: Data from a European multicenter retrospective study

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks