The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.
Marine pharmacology in 2005–6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action
Open accessAbstract
BACKGROUND The review presents the 2005–2006 peer-reviewed marine pharmacology literature, and follows a similar format to the authors’ 1998–2004 reviews. The preclinical pharmacology of chemically characterized marine compounds isolated from marine animals, algae, fungi and bacteria is systematically presented. RESULTS Anthelminthic, antibacterial, anticoagulant, antifungal, antimalarial, antiprotozoal, antituberculosis and antiviral activities were reported for 78 marine chemicals. Additionally 47 marine compounds were reported to affect the cardiovascular, immune and nervous system as well as possess anti-inflammatory effects. Finally, 58 marine compounds were shown to bind to a variety of molecular targets, and thus could potentially contribute to several pharmacological classes. CONCLUSIONS Marine pharmacology research during 2005–2006 was truly global in nature, involving investigators from 32 countries, and the United States, and contributed 183 marine chemical leads to the research pipeline aimed at the discovery of novel therapeutic agents. SIGNIFICANCE Continued preclinical and clinical research with marine natural products demonstrating a broad spectrum of pharmacological activity and will probably result in novel therapeutic agents for the treatment of multiple disease categories.
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Citations
Cites
Developing a new resource for drug discovery: marine actinomycete bacteria
Fenical, W., & Jensen, P. R. (2006) · Nature Chemical Biology · doi:10.1038/nchembio841 · Cited by 786
Bioactive compounds from marine processing byproducts – A review
Kim, S.-K., & Mendis, E. (2006) · Food Research International · doi:10.1016/j.foodres.2005.10.010 · Cited by 737
Drug discovery from natural sources
Chin, Y.-W., Balunas, M. J., Chai, H. B., & Kinghorn, A. D. (2006) · The AAPS Journal · doi:10.1007/bf02854894 · Cited by 662
Bioactive compounds from cyanobacteria and microalgae: an overview
Singh, S., Kate, B. N., & Banerjee, U. C. (2005) · Critical Reviews in Biotechnology · doi:10.1080/07388550500248498 · Cited by 619
The Renaissance of Natural Products as Drug Candidates
Paterson, I., & Anderson, E. A. (2005) · Science · doi:10.1126/science.1116364 · Cited by 559
Mori, T., O'Keefe, B. R., Sowder, R. C., Bringans, S., Gardella, R., Berg, S., Cochran, P., Turpin, J. A., Buckheit, R. W., McMahon, J. B., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m411122200 · Cited by 445
Gul, W., & Hamann, M. T. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.09.007 · Cited by 433
Self-citationMarine natural products and their potential applications as anti-infective agents
Donia, M., & Hamann, M. T. (2003) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(03)00655-8 · Cited by 425
Self-citationBiodiversity: A continuing source of novel drug leads
Cragg, G. M., & Newman, D. J. (2005) · Pure and Applied Chemistry · doi:10.1351/pac200577010007 · Cited by 406
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A
Bordeleau, M.-E., Mori, A., Oberer, M., Lindqvist, L., Chard, L. S., Higa, T., Belsham, G. J., Wagner, G., Tanaka, J., & Pelletier, J. (2006) · Nature Chemical Biology · doi:10.1038/nchembio776 · Cited by 366
Cited by
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,866
Wijesekara, I., Pangestuti, R., & Kim, S.-K. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.10.062 · Cited by 992
The odyssey of marine pharmaceuticals: a current pipeline perspective
Mayer, A. M. S., Glaser, K. B., Cuevas, C., Jacobs, R. S., Kem, W., Little, R. D., McIntosh, J. M., Newman, D. J., Potts, B. C., & Shuster, D. E. (2010) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2010.02.005 · Cited by 666
Self-citationMartins, A., Vieira, H., Gaspar, H., & Santos, S. (2014) · Marine Drugs · doi:10.3390/md12021066 · Cited by 572
Blunt, J. W., Copp, B. R., Munro, M. H. G., Northcote, P. T., & Prinsep, M. R. (2011) · Nat. Prod. Rep. · doi:10.1039/c005001f · Cited by 470
Metadata
- Authors
- Mayer, A. M. S., Rodríguez, A. D., Berlinck, R. G. S., & Hamann, M. T.
- Venue
- Biochimica et Biophysica Acta (BBA) - General Subjects
- Publisher
- Elsevier BV
- Published
- 2009-05
- Volume
- 1790
- Issue
- 5
- Pages
- 283-308
- ISSN
- 0304-4165 (ISSN-L)
- OpenAlex
- W2068109394
- Cited by
- 458
- References
- 125
- FWCI
- 41.22
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Marine pharmacology in 2005–6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. https://app.cochat.ai/papers/10.1016/j.bbagen.2009.03.011
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- Mayer, A. M. S., Rodríguez, A. D., Berlinck, R. G. S., & Hamann, M. T. (2009). Marine pharmacology in 2005–6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. Biochimica et Biophysica Acta (BBA) - General Subjects. https://doi.org/10.1016/j.bbagen.2009.03.011
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