Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells

The Pathobiology of Diabetic Complications

Brownlee, M. (2005) · Diabetes · doi:10.2337/diabetes.54.6.1615 · Cited by 5,339 · see citing works

Role of Oxidative Stress in Development of Complications in Diabetes

Baynes, J. (1991) · Diabetes · doi:10.2337/diab.40.4.405 · Cited by 3,791 · see citing works

Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins

Yan, S. D., Schmidt, A. M., Anderson, G. M., Zhang, J., Brett, J., Zou, Y., Pinsky, D. J., & Stern, D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36966-1 · Cited by 1,305 · see citing works

Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values

Mofrad, P., Contos, M., Haque, M., Sargeant, C. C., Fisher, R., Luketic, V., Sterling, R., Shiffman, M., Stravitz, R., & Sanyal, A. (2003) · Hepatology · doi:10.1053/jhep.2003.50229 · Cited by 1,221 · see citing works

Molecular Understanding of Hyperglycemia's Adverse Effects for Diabetic Complications

Sheetz, M. J. (2002) · JAMA · doi:10.1001/jama.288.20.2579 · Cited by 1,003 · see citing works

Insulin resistance: a metabolic pathway to chronic liver disease

Bugianesi, E., McCullough, A. J., & Marchesini, G. (2005) · Hepatology · doi:10.1002/hep.20920 · Cited by 900 · see citing works

Advanced glycation end products contribute to amyloidosis in Alzheimer disease

Vitek, M. P., Bhattacharya, K., Glendening, J. M., Stopa, E., Vlassara, H., Bucala, R., Manogue, K., & Cerami, A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.11.4766 · Cited by 806 · see citing works

Nonenzymatic Browning in Vivo: Possible Process for Aging of Long-Lived Proteins

Monnier, V. M., & Cerami, A. (1981) · Science · doi:10.1126/science.6779377 · Cited by 768 · see citing works

Diabetes and advanced glycation endproducts

Vlassara, H., & Palace, M. R. (2002) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2002.00932.x · Cited by 716 · see citing works

The AGE‐receptor in the pathogenesis of diabetic complications

Vlassara, H. (2001) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.233 · Cited by 301 · see citing works

A Role for Advanced Glycation End Products in Diminished Bone Healing in Type 1 Diabetes

Santana, R. B., Xu, L., Babakhanlou‐Chase, H., Amar, S., Graves, D. T., & Trackman, P. C. (2003) · Diabetes · doi:10.2337/diabetes.52.6.1502 · Cited by 251 · see citing works

Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging.

Araki, N., Ueno, N., Chakrabarti, B., et al. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50004-7 · Cited by 250 · see citing works

Glucosylation of human collagen in aging and diabetes mellitus.

Schnider, S. L., & Kohn, R. R. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109950 · Cited by 212 · see citing works

Nonenzymatic glycosylation of peripheral nerve protein in diabetes mellitus.

Vlassara, H., Brownlee, M., & Cerami, A. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.8.5190 · Cited by 201 · see citing works

Ethanol Cytotoxicity to a Transfected HepG2 Cell Line Expressing Human Cytochrome P4502E1

Wu, D., & Cederbaum, A. I. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.39.23914 · Cited by 194 · see citing works

Nonalcoholic fatty liver disease in type 2 diabetes mellitus

Cusi, K. J. (2009) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e3283293015 · Cited by 185 · see citing works

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression

Woodcroft, K. J., Hafner, M. S., & NOVAK, R. F. (2002) · Hepatology · doi:10.1053/jhep.2002.30691 · Cited by 164 · see citing works

Advanced glycation end products and diabetic complications: A General overview

Peppa, Μ., & Vlassara, H. (2005) · HORMONES · doi:10.14310/horm.2002.11140 · Cited by 153 · see citing works

Glycation as the glucose link to diabetic complications.

Gugliucci, A. (2000) · PubMed · Cited by 127 · see citing works

Recombinant Hep G2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity

Donohue, T. M., Osna, N. A., & Clemens, D. L. (2005) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2005.07.010 · Cited by 124 · see citing works

Cytochrome P450 2E1‐dependent oxidant stress and upregulation of anti‐oxidant defense in liver cells

Cederbaum, A. I. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04595.x · Cited by 118 · see citing works

Reductive Metabolism of AGE Precursors: A Metabolic Route for Preventing AGE Accumulation in Cardiovascular Tissue

Baba, S. P., Barski, O. A., Ahmed, Y., O’Toole, T. E., Conklin, D. J., Bhatnagar, A., & Srivastava, S. (2009) · Diabetes · doi:10.2337/db09-0375 · Cited by 117 · see citing works

Review article: type 2 diabetes and chronic liver disease in the Verona diabetes study

Trombetta, M., Spiazzi, G., Zoppini, G., & Muggeo, M. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02590.x · Cited by 115 · see citing works

The role of advanced glycation end products in the development of atherosclerosis

Peppa, Μ., Uribarri, J., & Vlassara, H. (2004) · Current Diabetes Reports · doi:10.1007/s11892-004-0008-6 · Cited by 112 · see citing works

Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells

Iwamoto, K., Kanno, K., Hyogo, H., Yamagishi, S., Takeuchi, M., Tazuma, S., & Chayama, K. (2008) · Journal of Gastroenterology · doi:10.1007/s00535-007-2152-7 · Cited by 110 · see citing works

Posttranslational Modification of Human Glyoxalase 1 Indicates Redox-Dependent Regulation

Birkenmeier, G., Stegemann, C., Hoffmann, R., Günther, R., Huse, K., & Birkemeyer, C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010399 · Cited by 95 · see citing works

Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells

Clemens, D. L., Forman, A., Jerrells, T. R., Sorrell, M. F., & Tuma, D. J. (2002) · Hepatology · doi:10.1053/jhep.2002.32668 · Cited by 82 · see citing works

Fatty Liver and Nonalcoholic Steatohepatitis. Where Do We Stand and Where Are We Going?

Lonardo, A. (1999) · Digestive Diseases · doi:10.1159/000016909 · Cited by 80 · see citing works

MOLECULAR ENZYMOLOGY OF THE GLYOXALASE SYSTEM

Mannervik, B. (2008) · Drug metabolism and drug interactions · doi:10.1515/dmdi.2008.23.1-2.13 · Cited by 74 · see citing works

Acute ethanol exposure inhibits insulin signaling in the liver

He, J., de la Monte, S. M., & Wands, J. R. (2007) · Hepatology · doi:10.1002/hep.21904 · Cited by 71 · see citing works

Characterization of Cytochrome P4502E1 Turnover in Transfected HepG2 Cells Expressing Human CYP2E1

Yang, M., & Cederbaum, A. I. (1997) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.9907 · Cited by 66 · see citing works

Ethanol Metabolism Alters Interferon Gamma Signaling in Recombinant HepG2 Cells *

Osna, N. A., Clemens, D. L., & Donohue, T. M. (2005) · Hepatology · doi:10.1002/hep.20909 · Cited by 51 · see citing works

Proteasome Activation by Hepatitis C Core Protein Is Reversed by Ethanol-Induced Oxidative Stress

Osna, N. A., White, R. L., Krutik, V. M., Wang, T., Weinman, S. A., & Donohue, T. M. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.02.063 · Cited by 50 · see citing works

Induction of cytochrome promotes liver injury in ob/ob mice

Dey, A., & Cederbaum, A. I. (2007) · Hepatology · doi:10.1002/hep.21603 · Cited by 46 · see citing works

Advanced Glycoxidation: A New Risk Factor for Cardiovascular Disease?

Peppa, Μ., Uribarri, J., & Vlassara, H. (2002) · Cardiovascular Toxicology · doi:10.1385/ct:2:4:275 · Cited by 38 · see citing works

Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1

Dey, A., Kessova, I. G., & Cederbaum, A. I. (2006) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2006.01.013 · Cited by 36 · see citing works

Relationship between oxidative stress and hepatic glutathione levels in ethanol-mediated apoptosis of polarized hepatic cells

McVicker, B. L., Tuma, P. L., Kharbanda, K. K., et al. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.2609 · Cited by 35 · see citing works

Geldanamycin, an Inhibitor of Hsp90, Potentiates Cytochrome P4502E1-Mediated Toxicity in HepG2 Cells

Dey, A., & Cederbaum, A. I. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.101808 · Cited by 32 · see citing works

Fluorescent advanced glycation end products in the detection of factual stages of cartilage degeneration

Handl, M., Filová, E., Kubala, M. E., Lánský, Z., Koláčná, L., Vorlíček, J., Trč, T., & Amler, E. (2007) · Physiological Research · doi:10.33549/physiolres.930934 · Cited by 32 · see citing works

Hepatic changes in adenine nucleotide levels and adenosine 3'-monophosphate forming enzyme in streptozotocin-induced diabetic mice

Miyamoto, A., Takeshita, M., Pan-Hou, H. S. K., & Fujimori, H. (2008) · The Journal of Toxicological Sciences · doi:10.2131/jts.33.209 · Cited by 19 · see citing works

Increased oxidative stress and toxicity in ADH and CYP2E1 overexpressing human hepatoma VL-17A cells exposed to high glucose

Chandrasekaran, K., Swaminathan, K., Kumar, S. M., Clemens, D. L., & Dey, A. (2012) · Integrative Biology · doi:10.1039/c2ib00155a · Cited by 18 · see citing works

Glycation of aspartate aminotransferase by methylglyoxal, effect of hydroxycitric and uric acid

Boušová, I., Bacílková, E., Dobrijević, S., & Dršata, J. (2009) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-009-0161-y · Cited by 8 · see citing works

Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro

Kornbrust, D. J., & Dietz, D. (1985) · Chemico-Biological Interactions · doi:10.1016/0009-2797(85)90037-7 · Cited by 5 · see citing works

Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury

Rungratanawanich, W., Qu, Y., Wang, X., Essa, M. M., & Song, B.-J. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00561-7 · Cited by 411 · see citing works

[Influence of long-term combined gamma-radiation and ethanol on cytochrome P450 2E1 expression in the mice liver].

Maksymchuk, O., Bobyk, V. I., Ll, S., et al. (2009) · PubMed · Cited by 7 · see citing works

Research Progress on Cytochrome P450 2E1

Wu, S. (2014) · China Animal Husbandry & Veterinary Medicine · Cited by 1 · see citing works

The Metabolic Rate Constants and Specific Activity of Human and Rat Hepatic Cytochrome P-450 2E1 Toward Toluene and Chloroform

Lipscomb, J. C., Barton, H. A., Tornero‐Velez, R., Evans, M. V., Alcasey, S., SNAWDER, J. E., & Laskey, J. W. (2004) · Journal of Toxicology and Environmental Health · doi:10.1080/15287390490425588 · Cited by 26 · see citing works

Establishment of a p -nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro

Mahli, A., Thasler, W. E., & Hellerbrand, C. (2018) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2018.1539800 · Cited by 5 · see citing works

A study for regulation of ethanol-inducible P450(CYP2E1) on CCl4-induced hepatic damage

Park, S. M., Park, E. J., Ko, G., Kim, J., & Sohn, D. H. (1995) · Archives of Pharmacal Research · doi:10.1007/bf02979192 · Cited by 2 · see citing works