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Cited by 257

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Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging

Open access
Eberlin, Livia S., Ferreira, Christina R., Dill, Allison L., Ifa, Demian R., Cooks, R. Graham·2011·Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Abstract

Desorption electrospray ionization mass spectrometry (DESI-MS) imaging of biological samples allows untargeted analysis and structural characterization of lipids ionized from the near-surface region of a sample under ambient conditions. DESI is a powerful and sensitive MS ionization method for 2D and 3D imaging of lipids from direct and unmodified complex biological samples. This review describes the strengths and limitations of DESI-MS for lipid characterization and imaging together with the technical workflow and a survey of applications. Included are discussions of lipid mapping and biomarker discovery as well as a perspective on the future of DESI imaging.

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Crossref · 10.1016/j.bbalip.2011.05.006

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Metadata

Authors
Eberlin, L. S., Ferreira, C. R., Dill, A. L., Ifa, D. R., & Cooks, R. G.
Venue
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Publisher
Elsevier BV
Published
2011-11
Volume
1811
Issue
11
Pages
946-960
ISSN
1388-1981 (ISSN-L)
OpenAlex
W2024931221
Cited by
257
References
2
FWCI
9.03
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging. https://app.cochat.ai/papers/10.1016/j.bbalip.2011.05.006
The paper
Eberlin, L. S., Ferreira, C. R., Dill, A. L., Ifa, D. R., & Cooks, R. G. (2011). Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. https://doi.org/10.1016/j.bbalip.2011.05.006

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