Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 37

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation

da Silva, Robin P., Kelly, Karen B., Leonard, Kelly-Ann, Jacobs, René L.·2014·Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.bbalip.2014.09.001

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 3 references

Research works printed but not linked: 35

  1. Dowman, 2011, Systematic review: the diagnosis and staging of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis, Aliment. Pharmacol. Ther., 33, 525, 10.1111/j.1365-2036.2010.04556.x · DOI · Paper page
  2. Marchesini, 2003, Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome, Hepatology, 37, 917, 10.1053/jhep.2003.50161 · DOI · Paper page
  3. Vance, 2007, Hepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiology, J. Biol. Chem., 282, 33237, 10.1074/jbc.R700028200 · DOI
  4. Vance, 2013, Physiological roles of phosphatidylethanolamine N-methyltransferase, Biochim. Biophys. Acta, 1831, 626, 10.1016/j.bbalip.2012.07.017 · DOI
  5. Lu, 2012, S-adenosylmethionine in liver health, injury, and cancer, Physiol. Rev., 92, 1515, 10.1152/physrev.00047.2011 · DOI · Paper page
  6. Ji, 2003, Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice, Gastroenterology, 124, 1488, 10.1016/S0016-5085(03)00276-2 · DOI · Paper page
  7. Song, 2007, Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis, Am. J. Physiol. Gastrointest. Liver Physiol., 293, G894, 10.1152/ajpgi.00133.2007 · DOI
  8. Kwon do, 2009, Impaired sulfur-amino acid metabolism and oxidative stress in nonalcoholic fatty liver are alleviated by betaine supplementation in rats, J. Nutr., 139, 63, 10.3945/jn.108.094771 · DOI
  9. Zhao, 2009, Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice, Arterioscler. Thromb. Vasc. Biol., 29, 1349, 10.1161/ATVBAHA.109.188672 · DOI
  10. Guthmiller, 1994, Cloning and sequencing of rat kidney L-arginine:glycine amidinotransferase. Studies on the mechanism of regulation by growth hormone and creatine, J. Biol. Chem., 269, 17556, 10.1016/S0021-9258(17)32477-8 · DOI
  11. Deminice, 2011, Creatine supplementation prevents the accumulation of fat in the livers of rats fed a high-fat diet, J. Nutr., 141, 1799, 10.3945/jn.111.144857 · DOI · Paper page
  12. Erickson, 2013, Endoplasmic reticulum-localized hepatic lipase decreases triacylglycerol storage and VLDL secretion, Biochim. Biophys. Acta, 1831, 1113, 10.1016/j.bbalip.2013.01.017 · DOI
  13. Ko, 2009, Es-x/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes, Biochim. Biophys. Acta, 1791, 1133, 10.1016/j.bbalip.2009.07.006 · DOI
  14. Butkinaree, 2014, A regulator of secretory vesicle size, Kelch-like protein 12, facilitates the secretion of apolipoprotein B100 and very-low-density lipoproteins—brief report, Arterioscler. Thromb. Vasc. Biol., 34, 251, 10.1161/ATVBAHA.113.302728 · DOI
  15. Caviglia, 2011, Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy, J. Lipid Res., 52, 1636, 10.1194/jlr.M016931 · DOI
  16. Folch, 1957, A simple method for the isolation and purification of total lipides from animal tissues, J. Biol. Chem., 226, 497, 10.1016/S0021-9258(18)64849-5 · DOI · Paper page
  17. Jacobs, 2008, Hepatic CTP:phosphocholine cytidylyltransferase-alpha is a critical predictor of plasma high density lipoprotein and very low density lipoprotein, J. Biol. Chem., 283, 2147, 10.1074/jbc.M706628200 · DOI · Paper page
  18. Myher, 1984, Determination of plasma total lipid profiles by capillary gas–liquid chromatography, J. Biochem. Biophys. Methods, 10, 13, 10.1016/0165-022X(84)90046-0 · DOI
  19. Jacobs, 2007, Inhibition of hepatic phosphatidylcholine synthesis by 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside is independent of AMP-activated protein kinase activation, J. Biol. Chem., 282, 4516, 10.1074/jbc.M605702200 · DOI
  20. Carling, 2008, The regulation of AMP-activated protein kinase by upstream kinases, Int. J. Obes., 32, S55, 10.1038/ijo.2008.124 · DOI · Paper page
  21. Davies, 1990, Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase, Eur. J. Biochem., 187, 183, 10.1111/j.1432-1033.1990.tb15293.x · DOI · Paper page
  22. Stead, 2001, Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate, Am. J. Physiol. Endocrinol. Metab., 281, E1095, 10.1152/ajpendo.2001.281.5.E1095 · DOI
  23. Kharbanda, 2014, Increased methylation demand exacerbates ethanol-induced liver injury, Exp. Mol. Pathol., 97, 49, 10.1016/j.yexmp.2014.05.006 · DOI
  24. Huang, 2013, Inhibitors of fatty acid synthesis induce PPAR alpha-regulated fatty acid beta-oxidative genes: synergistic roles of L-FABP and glucose, PPAR Res., 2013, 865604, 10.1155/2013/865604 · DOI
  25. Spann, 2006, Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis, J. Biol. Chem., 281, 33066, 10.1074/jbc.M607148200 · DOI
  26. Fisher, 2012, The degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways, Biochim. Biophys. Acta, 1821, 778, 10.1016/j.bbalip.2012.02.001 · DOI
  27. Finck, 2006, Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway, Cell Metab., 4, 199, 10.1016/j.cmet.2006.08.005 · DOI · Paper page
  28. Kok, 2013, Differential regulation of the expressions of the PGC-1alpha splice variants, lipins, and PPARalpha in heart compared to liver, J. Lipid Res., 54, 1662, 10.1194/jlr.M036624 · DOI
  29. Csaki, 2013, Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling, Prog. Lipid Res., 52, 305, 10.1016/j.plipres.2013.04.001 · DOI
  30. Qi, 2012, The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2, J. Lipid Res., 53, 1106, 10.1194/jlr.M020156 · DOI
  31. Cui, 1993, Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver, J. Biol. Chem., 268, 16655, 10.1016/S0021-9258(19)85468-6 · DOI
  32. Carlson, 1999, Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise, J. Appl. Physiol., 86, 669, 10.1152/jappl.1999.86.2.669 · DOI
  33. Brownsey, 2006, Regulation of acetyl-CoA carboxylase, Biochem. Soc. Trans., 34, 223, 10.1042/BST20060223 · DOI · Paper page
  34. Rahimi, 2011, Creatine supplementation decreases oxidative DNA damage and lipid peroxidation induced by a single bout of resistance exercise, J. Strength Cond. Res., 25, 3448, 10.1519/JSC.0b013e3182162f2b · DOI · Paper page
  35. Adams, 2005, Recent concepts in non-alcoholic fatty liver disease, Diabet. Med., 22, 1129, 10.1111/j.1464-5491.2005.01748.x · DOI · Paper page

Cited by

See all 37

Metadata

Authors
da Silva, R. P., Kelly, K. B., Leonard, K.-A., & Jacobs, R. L.
Venue
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Publisher
Elsevier BV
Published
2014-11
Volume
1841
Issue
11
Pages
1639-1646
ISSN
1388-1981
Cited by
37
References
3
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
  • Canadian Institutes of Health Research (133505)
  • Canadian Foundation for Innovation (29893)
  • Alberta Ministry for Advanced Education and Technology
  • Natural Sciences and Engineering Research Council of Canada

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation. https://app.cochat.ai/papers/10.1016/j.bbalip.2014.09.001
The paper
da Silva, R. P., Kelly, K. B., Leonard, K.-A., & Jacobs, R. L. (2014). Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. https://doi.org/10.1016/j.bbalip.2014.09.001

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.