Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase

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The Structures and Related Functions of Phosphorylase a

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Regulation of fatty acid synthesis via phosphorylation of acetyl-CoA carboxylase

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Structure of the coding sequence and primary amino acid sequence of acetyl-coenzyme A carboxylase.

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Characterisation of a Reconstituted Mg‐ATP‐Dependent Protein Phosphatase

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Acetyl-Coenzyme-A Carboxylase from Rat Liver. Subunit Structure and Proteolytic Modification

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The low activity of acetyl‐CoA car☐ylase in basal and glucagon‐stimulated hepatocytes is due to phosphorylation by the AMP‐activated protein kinase and not cyclic AMP‐dependent protein kinase

Sim, A. T. R., & Hardie, D. G. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80445-9 · Cited by 148 · see citing works

Primary structure of chicken liver acetyl-CoA carboxylase deduced from cDNA sequence.

Takai, T., Yokoyama, C., Wada, K., & Tanabe, T. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69116-1 · Cited by 115 · see citing works

Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast‐atom‐bombardment mass spectrometry

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Glucagon inhibits fatty acid synthesis in isolated hepatocytes via phosphorylation of acetyl-CoA carboxylase by cyclic-AMP-dependent protein kinase

Holland, R., Witters, L. A., & Hardie, D. G. (1984) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1984.tb08105.x · Cited by 99 · see citing works

Analysis of sites phosphorylated on acetyl‐CoA carboxylase in response to insulin in isolated adipocytes

Haystead, T., Campbell, D. G., & Hardie, D. G. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14203.x · Cited by 69 · see citing works

Negative interactions between phosphorylation of acetyl‐CoA carboxylase by the cyclic AMP‐dependent and AMP‐activated protein kinases

Munday, M. R., Carling, D., & Hardie, D. G. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)81251-1 · Cited by 53 · see citing works

Isolation of three cyclic-AMP-independent acetyl-CoA carboxylase kinases from lactating rat mammary gland and characterization of their effects on enzyme activity

Munday, M. R., & Hardie, D. G. (1984) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1984.tb08237.x · Cited by 43 · see citing works

Mapping of catalytic domains and phosphorylation sites in the multifunctional pyrimidine‐biosynthetic protein CAD

Carrey, E. A., & Hardie, D. G. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb13828.x · Cited by 36 · see citing works

Insulin and phorbol ester stimulate phosphorylation of acetyl‐CoA carboxylase at similar sites in isolated adipocytes

Haystead, T., & Hardie, D. G. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14202.x · Cited by 35 · see citing works

Characterization of the phosphorylation of rat mammary ATP‐citrate lyase and acetyl‐CoA carboxylase by Ca2+ and calmodulin‐dependent multiprotein kinase and Ca2+ and phospholipid‐dependent protein kinase

Hardie, D. G., Carling, D., Ferrari, S. M., et al. (1986) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1986.tb09702.x · Cited by 28 · see citing works

Dephosphorylation and activation of chicken liver acetyl‐coenzyme‐A carboxylase

Wada, K., & Tanabe, T. (1983) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1983.tb07612.x · Cited by 28 · see citing works

Regulation of mammalian acetyl‐CoA carboxylase

Guy, P. S., & Hardie, D. G. (1981) · FEBS Letters · doi:10.1016/0014-5793(81)80428-0 · Cited by 23 · see citing works

Muscle and liver pyruvate kinases are closely related: amino acid sequence comparisons

Hoar, C. G., Nicoll, G. W., Schiltz, E., et al. (1984) · FEBS Letters · doi:10.1016/0014-5793(84)80507-4 · Cited by 19 · see citing works

Proteolysis of liver acetyl coenzyme A carboxylase by cathepsin B

Wada, K., & Tanabe, T. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)80234-9 · Cited by 5 · see citing works

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

Hatori, M., Vollmers, C., Zarrinpar, A., DiTacchio, L., Bushong, E. A., Gill, S., Leblanc, M., Chaix, A., Joens, M., Fitzpatrick, J. A. J., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.04.019 · Cited by 1,986 · see citing works

The AMP‐Activated Protein Kinase: Fuel Gauge of the Mammalian Cell?

Hardie, D. G., & Carling, D. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00259.x · Cited by 1,317 · see citing works

Tumor suppressors and cell metabolism: a recipe for cancer growth

Jones, R. G., & Thompson, C. B. (2009) · Genes & Development · doi:10.1101/gad.1756509 · Cited by 1,085 · see citing works

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J.-M., Lee, C. H., Oh, W. K., Kim, C. T., et al. (2006) · Diabetes · doi:10.2337/db06-0006 · Cited by 1,054 · see citing works

AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer

Hardie, D. G. (2013) · Diabetes · doi:10.2337/db13-0368 · Cited by 458 · see citing works

The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid β-oxidation

Buzzai, M., Bauer, D. E., Jones, R. G., DeBerardinis, R. J., Hatzivassiliou, G., Elstrom, R. L., & Thompson, C. B. (2005) · Oncogene · doi:10.1038/sj.onc.1208622 · Cited by 357 · see citing works

Regulation of 5′AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle

Wojtaszewski, J. F. P., MacDonald, C., Nielsen, J. N., Hellsten, Y., Hardie, D. G., Kemp, B. E., Kiens, B., & Richter, E. A. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00436.2002 · Cited by 348 · see citing works

AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress

Nagata, D., Mogi, M., & Walsh, K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300643200 · Cited by 331 · see citing works

Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte

Chan, A. Y. M., Soltys, C.-L. M., Young, M. E., Proud, C. G., & Dyck, J. R. B. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403528200 · Cited by 331 · see citing works

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling

Lin, R., Elf, S., Shan, C., Kang, H.-B., Ji, Q., Zhou, L., Hitosugi, T., Zhang, L., Zhang, S., Seo, J. H., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3255 · Cited by 287 · see citing works

<scp>AMP</scp> ‐activated protein kinase: a key regulator of energy balance with many roles in human disease

Grahame Hardie, D. (2014) · Journal of Internal Medicine · doi:10.1111/joim.12268 · Cited by 285 · see citing works

AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole-body levels

Hardie, D. G. (2014) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071812-161148 · Cited by 281 · see citing works

Phosphorylation of rat muscle acetyl-coa carboxylase by amp-activated protein kinase and protein kinase A

Winder, W. W., Wilson, H. A., Hardie, D. G., Rasmussen, B. B., Hutber, C. A., Call, G. B., Clayton, R. D., Conley, L. M., Yoon, S., & Zhou, B. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.1.219 · Cited by 237 · see citing works

Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP‐activated protein kinase: A sensitive mechanism to protect the cell against ATP depletion

MOORE, F., WEEKES, J., & HARDIE, D. G. (1991) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1991.tb16172.x · Cited by 223 · see citing works

AMPK‐independent pathways regulate skeletal muscle fatty acid oxidation

Dzamko, N., Schertzer, J. D., Ryall, J. G., Steel, R., Macaulay, S. L., Wee, S., Chen, Z., Michell, B. J., Oakhill, J. S., Watt, M. J., et al. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.159814 · Cited by 147 · see citing works

Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance

Wredenberg, A., Freyer, C., Sandström, M. E., Katz, A., Wibom, R., Westerblad, H., & Larsson, N.-G. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.09.029 · Cited by 141 · see citing works

Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes

Berggreen, C., Gormand, A., Omar, B., Degerman, E., & Göransson, O. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90596.2008 · Cited by 118 · see citing works

Metabolic control by AMPK in white adipose tissue

Göransson, O., Kopietz, F., & Rider, M. H. (2023) · Trends in Endocrinology &amp; Metabolism · doi:10.1016/j.tem.2023.08.011 · Cited by 74 · see citing works

Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity

Beck Jørgensen, S., O’Neill, H. M., Hewitt, K., Kemp, B. E., & Steinberg, G. R. (2009) · Diabetologia · doi:10.1007/s00125-009-1483-8 · Cited by 42 · see citing works

Complex Formation and Regulation of Escherichia coli Acetyl-CoA Carboxylase

Broussard, T. C., Price, A. E., Laborde, S. M., & Waldrop, G. L. (2013) · Biochemistry · doi:10.1021/bi4000707 · Cited by 46 · see citing works

Complex formation and regulation of Escherichia coli acetyl-CoA carboxylase

Broussard, T. C. (2013) · doi:10.31390/gradschool_dissertations.2741 · Cited by 8 · see citing works

Acetyl-CoA carboxylase exerts strong flux control over lipid synthesis in plants

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Biotin Carboxyl Carrier Protein and Biotin Carboxylase Subunits of the Multi Subunit form of Acetyl CoA Carboxylase from Brassica Napus

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ACETYL COA CARBOXYLASE, II. DEMONSTRATION OF BIOTIN-PROTEIN AND BIOTIN CARBOXYLASE SUBUNITS

Alberts, A. W., Nervi, A. M., & Vagelos, P. R. (1969) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.63.4.1319 · Cited by 78 · see citing works