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The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Inositol trisphosphate and calcium signalling mechanisms

Open access
Berridge, Michael J.·2009·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Abstract

Studies on control of fluid secretion by an insect salivary gland led to the discovery of inositol trisphosphate (IP3) and its role in calcium signalling. Many cell stimuli act on receptors that are coupled to phospholipase C that hydrolyses phosphatidylinosol 4,5-bisphosphate (PIP2) to release IP3 to the cytosol. IP3 receptors located on the endoplasmic reticulum respond to this elevation of IP3 by releasing Ca2+, which is often organized into characteristic spatial (elementary events and waves) and temporal (Ca2+ oscillations) patterns. This IP3/Ca2+ pathway is a remarkably versatile signalling system that has been adapted to control processes as diverse as fertilization, proliferation, contraction, cell metabolism, vesicle and fluid secretion and information processing in neuronal cells.

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Crossref · 10.1016/j.bbamcr.2008.10.005

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Metadata

Authors
Berridge, M. J.
Venue
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Publisher
Elsevier BV
Published
2009-06
Volume
1793
Issue
6
Pages
933-940
ISSN
0167-4889 (ISSN-L)
OpenAlex
W2150861334
Cited by
777
References
6
FWCI
20.94
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Inositol trisphosphate and calcium signalling mechanisms. https://app.cochat.ai/papers/10.1016/j.bbamcr.2008.10.005
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Berridge, M. J. (2009). Inositol trisphosphate and calcium signalling mechanisms. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. https://doi.org/10.1016/j.bbamcr.2008.10.005

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.