The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
The immunoregulatory role of dopamine: An update
Open accessAbstract
The neurotransmitter dopamine (DA) is an important molecule bridging the nervous and immune systems. DA through autocrine/paracrine manner modulates the functions of immune effector cells by acting through its receptors present in these cells. DA also has unique and opposite effects on T cell functions. Although DA activates naïve or resting T cells, but it inhibits activated T cells. In addition, changes in the expression of DA receptors and their signaling pathways especially in T cells are associated with altered immune functions in disorders like schizophrenia and Parkinson’s disease. These results suggest an immunoregulatory role of DA. Therefore targeting DA receptors and their signaling pathways in these cells by using DA receptor agonists and antagonists may be useful for the treatment of diseases where DA induced altered immunity play a pathogenic role.
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Cites
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Cited by
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome
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Inflammation in Parkinson’s Disease: Mechanisms and Therapeutic Implications
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Commensal clostridia: Leading players in the maintenance of gut homeostasis
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Metadata
- Authors
- Sarkar, C., Basu, B., Chakroborty, D., Dasgupta, P. S., & Basu, S.
- Venue
- Brain, Behavior, and Immunity
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 24
- Issue
- 4
- Pages
- 525-528
- ISSN
- 0889-1591 (ISSN-L)
- OpenAlex
- W2074869406
- Cited by
- 323
- References
- 44
- FWCI
- 2.49
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.