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The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.

The immunoregulatory role of dopamine: An update

Open access
Sarkar, Chandrani, Basu, Biswarup, Chakroborty, Debanjan, Dasgupta, Partha Sarthi, Basu, Sujit·2010·Brain, Behavior, and Immunity

Abstract

The neurotransmitter dopamine (DA) is an important molecule bridging the nervous and immune systems. DA through autocrine/paracrine manner modulates the functions of immune effector cells by acting through its receptors present in these cells. DA also has unique and opposite effects on T cell functions. Although DA activates naïve or resting T cells, but it inhibits activated T cells. In addition, changes in the expression of DA receptors and their signaling pathways especially in T cells are associated with altered immune functions in disorders like schizophrenia and Parkinson’s disease. These results suggest an immunoregulatory role of DA. Therefore targeting DA receptors and their signaling pathways in these cells by using DA receptor agonists and antagonists may be useful for the treatment of diseases where DA induced altered immunity play a pathogenic role.

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Metadata

Authors
Sarkar, C., Basu, B., Chakroborty, D., Dasgupta, P. S., & Basu, S.
Venue
Brain, Behavior, and Immunity
Publisher
Elsevier BV
Published
2010-05
Volume
24
Issue
4
Pages
525-528
ISSN
0889-1591 (ISSN-L)
OpenAlex
W2074869406
Cited by
323
References
44
FWCI
2.49
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The immunoregulatory role of dopamine: An update. https://app.cochat.ai/papers/10.1016/j.bbi.2009.10.015
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Sarkar, C., Basu, B., Chakroborty, D., Dasgupta, P. S., & Basu, S. (2010). The immunoregulatory role of dopamine: An update. Brain, Behavior, and Immunity. https://doi.org/10.1016/j.bbi.2009.10.015

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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