Cited by 558Long-Term Effects of COVID-19COVID-19 Clinical Research StudiesAcute Ischemic Stroke Management

The DOI matches its Crossref record; 22 of the 23 references it cites were found in a registry or an index.

COVID-19 presenting as stroke

Open access

Avula, Akshay, Nalleballe, Krishna, Narula, Naureen, Sapozhnikov, Steven, Dandu, Vasuki, Toom, Sudhamshi, Glaser, Allison, Elsayegh, Dany·2020·Brain, Behavior, and Immunity

DOI 10.1016/j.bbi.2020.04.077PMC PMC7187846

Open this paper in CoChat — free account

Abstract

Objective Acute stroke remains a medical emergency even during the COVID-19 pandemic. Most patients with COVID-19 infection present with constitutional and respiratory symptoms; while others present with atypical gastrointestinal, cardiovascular, or neurological manifestations. Here we present a series of four patients with COVID-19 that presented with acute stroke.Methods We searched the hospital databases for patients that presented with acute stroke and concomitant features of suspected COVID-19 infection. All patients who had radiographic evidence of stroke and PCR-confirmed COVID-19 infection were included in the study. Patients admitted to the hospital with PCR- confirmed COVID-19 disease whose hospital course was complicated with acute stroke while inpatient were excluded from the study. Retrospective patient data were obtained from electronic medical records. Informed consent was obtained.Results We identified four patients who presented with radiographic confirmation of acute stroke and PCR-confirmed SARS-CoV-2 infection. We elucidate the clinical characteristics, imaging findings, and the clinical course.Conclusions Timely assessment and hyperacute treatment is the key to minimize mortality and morbidity of patients with acute stroke. Stroke teams should be wary of the fact that COVID-19 patients can present with cerebrovascular accidents and should dawn appropriate personal protective equipment in every suspected patient. Further studies are urgently needed to improve current understandings of neurological pathology in the setting of COVID-19 infection.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.bbi.2020.04.077

Cites

22 of 22 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N.-H., Nitsche, A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.052 · Cited by 20,286
Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China
Mao, L., Jin, H., Wang, M., Hu, Y., Chen, S., He, Q., Chang, J., Hong, C., Zhou, Y., Wang, D., et al. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2020.1127 · Cited by 7,166
Incidence of thrombotic complications in critically ill ICU patients with COVID-19
Klok, F. A., Kruip, M. J. H. A., van der Meer, N. J. M., Arbous, M. S., Gommers, D. A. M. P. J., Kant, K. M., Kaptein, F. H. J., van Paassen, J., Stals, M. A. M., Huisman, M. V., et al. (2020) · Thrombosis Research · doi:10.1016/j.thromres.2020.04.013 · Cited by 5,028
Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
Wu, A., Peng, Y., Huang, B., Ding, X. L., Wang, X., Niu, P., Meng, J., Zhu, Z., Zhang, Z., Wang, J., et al. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.02.001 · Cited by 2,386
Nervous system involvement after infection with COVID-19 and other coronaviruses
Wu, Y., Xu, X., Chen, Z., Duan, J., Hashimoto, K., Yang, L., Liu, C., & Yang, C. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.03.031 · Cited by 2,046
A first case of meningitis/encephalitis associated with SARS-Coronavirus-2
Moriguchi, T., Harii, N., Goto, J., Harada, D., Sugawara, H., Takamino, J., Ueno, M., Sakata, H., Kondo, K., Myose, N., et al. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.03.062 · Cited by 2,024
Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)
Inciardi, R. M., Lupi, L., Zaccone, G., Italia, L., Raffo, M., Tomasoni, D., Cani, D., Cerini, M., Farina, D., Gavazzi, E., et al. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.1096 · Cited by 1,896
Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans
Fox, S., Akmatbekov, A., Harbert, J. L., Li, G., Brown, J. Q., & Heide, R. S. V. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30243-5 · Cited by 1,524
Acute Cerebrovascular Disease Following COVID-19: A Single Center, Retrospective, Observational Study
Li, Y., 王梦嵽, Zhou, Y., Chang, J., Xian, Y., Mao, L., Hong, C., Chen, S., Wang, Y., Wang, H., et al. (2020) · Stroke and Vascular Neurology · doi:10.1136/svn-2020-000431 · Cited by 1,071

Flagged first, then by citations

Show all 23 references

1 of the 23 references couldn’t be matched to a known paper.

Sorted by citations

Neurological associations of COVID-19
Ellul, M. A., Benjamin, L., Singh, B., Lant, S., Michael, B. D., Easton, A., Kneen, R., Defres, S., Sejvar, J., & Solomon, T. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30221-0 · Cited by 2,156
Acute Cerebrovascular Disease Following COVID-19: A Single Center, Retrospective, Observational Study
Li, Y., 王梦嵽, Zhou, Y., Chang, J., Xian, Y., Mao, L., Hong, C., Chen, S., Wang, Y., Wang, H., et al. (2020) · Stroke and Vascular Neurology · doi:10.1136/svn-2020-000431 · Cited by 1,071
COVID-19 Image Data Collection: Prospective Predictions are the Future
Cohen, J., Morrison, P., Dao, L., Roth, K., Duong, T. Q., & Ghassemi, M. (2020) · The Journal of Machine Learning for Biomedical Imaging · doi:10.59275/j.melba.2020-48g7 · Cited by 1,110
Neurological manifestations of COVID-19 and other coronavirus infections: A systematic review
Montalván, V., Lee, J., Bueso, T., Toledo, J. D., & Rivas, K. M. R. (2020) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2020.105921 · Cited by 670
COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation
Zabetakis, I., Lordan, R., Norton, C., & Τσούπρας, Α. (2020) · Nutrients · doi:10.3390/nu12051466 · Cited by 553
COVID-19 and multiorgan failure: A narrative review on potential mechanisms
Mokhtari, T., Hassani, F., Ghaffari, N., Ebrahimi, B., Yarahmadi, A., & Hassanzadeh, G. (2020) · Journal of Molecular Histology · doi:10.1007/s10735-020-09915-3 · Cited by 449
Neurological Manifestations of COVID‐19: A systematic review and current update
Whittaker, A., Anson, M., & Harky, A. (2020) · Acta Neurologica Scandinavica · doi:10.1111/ane.13266 · Cited by 441
COVID-19: from an acute to chronic disease? Potential long-term health consequences
Higgins, V., Sohaei, D., Diamandis, E. P., & Prassas, I. (2020) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2020.1860895 · Cited by 429
Neurobiology of COVID-19
Fotuhi, M., Mian, A., Meysami, S., & Raji, C. A. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200581 · Cited by 401
COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital
Thakur, K. T., Miller, E. H., Glendinning, M. D., Al‐Dalahmah, O., Banu, M. A., Boehme, A. K., Boubour, A., Bruce, S. S., Chong, A. M., Claassen, J., et al. (2021) · Brain · doi:10.1093/brain/awab148 · Cited by 396
Cognitive impairments four months after COVID-19 hospital discharge: pattern, severity and association with illness variables.
Miskowiak, K., Johnsen, S., Sattler, S., Nielsen, S., Kunalan, K., Rungby, J., Lapperre, T., & Porsberg, C. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.03.019 · Cited by 365
COVID-19 and ischemic stroke: a systematic review and meta-summary of the literature
Tan, Y. K., Goh, C. M. J. L., Leow, A. S., Tambyah, P. A., Ang, A., Yap, E. S., Tu, T. M., Sharma, V. K., Yeo, L. L. L., Chan, B., et al. (2020) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-020-02228-y · Cited by 325
A metabolic handbook for the COVID-19 pandemic
Ayres, J. S. (2020) · Nature Metabolism · doi:10.1038/s42255-020-0237-2 · Cited by 293
COVID‐19–associated Guillain‐Barré syndrome: The early pandemic experience
Caress, J. B., Castoro, R. J., Simmons, Z., Scelsa, S. N., Lewis, R. A., Ahlawat, A., & Narayanaswami, P. (2020) · Muscle & Nerve · doi:10.1002/mus.27024 · Cited by 292
Body Localization of ACE-2: On the Trail of the Keyhole of SARS-CoV-2
Salamanna, F., Maglio, M., Landini, M. P., & Fini, M. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.594495 · Cited by 298
Thrombosis in Coronavirus disease 2019 (COVID-19) through the prism of Virchow’s triad
Ahmed, S., Zimba, O., & Gasparyan, A. Y. (2020) · Clinical Rheumatology · doi:10.1007/s10067-020-05275-1 · Cited by 251
COVID-19 and metabolic disease: mechanisms and clinical management
Steenblock, C., Schwarz, P. E. H., Ludwig, B., Linkermann, A., Zimmet, P., Kulebyakin, K. Y., Va, T., Markov, A. G., Lehnert, H., de Angelis, M. H., et al. (2021) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(21)00244-8 · Cited by 256
Association of hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality: A systematic review
Zaki, N., Alashwal, H., & Ibrahim, S. (2020) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2020.07.005 · Cited by 248
Spectrum of neuropsychiatric manifestations in COVID-19.
Nalleballe, K., Reddy Onteddu, S., Sharma, R., Dandu, V., Brown, A., Jasti, M., Yadala, S., Veerapaneni, K., Siddamreddy, S., Avula, A., et al. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.06.020 · Cited by 235
Self-citation
Neurological manifestations associated with SARS-CoV-2 and other coronaviruses: A narrative review for clinicians
Maury, A., Lyoubi, A., Peiffer‐Smadja, N., de Broucker, T., & Meppiel, E. (2020) · Revue Neurologique · doi:10.1016/j.neurol.2020.10.001 · Cited by 241
Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic
Roy, D., Ghosh, R., Dubey, S., Dubey, M. J., Benito‐León, J., & Ray, B. K. (2020) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/cjn.2020.173 · Cited by 230
Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic
Sharifian, M., Huot, P., Osherov, M., Wen, D., Saveriano, A., Giacomini, P. S., Antel, J. P., & Mowla, A. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117085 · Cited by 230
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): a Systemic Infection
Synowiec, A., Szczepański, A., Barreto-Durán, E., Lie, L. K., & Pyrć, K. (2021) · Clinical Microbiology Reviews · doi:10.1128/cmr.00133-20 · Cited by 228
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19
Mirabelli, C., Wotring, J. W., Zhang, C. J., McCarty, S. M., Fursmidt, R. M., Pretto, C. D., Qiao, Y., Zhang, Y., Frum, T., Kadambi, N. S., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2105815118 · Cited by 219
COVID-19 Is an Independent Risk Factor for Acute Ischemic Stroke
Belani, P. B., Schefflein, J., Kihira, S., Rigney, B., Delman, B. N., Mahmoudi, K., Mocco, J., Majidi, S., Yeckley, J., Aggarwal, A., et al. (2020) · American Journal of Neuroradiology · doi:10.3174/ajnr.a6650 · Cited by 214
Neurological Manifestations of COVID-19 (SARS-CoV-2): A Review
Ahmed, M. U., Hanif, M., Ali, M. J., Haider, M. A., Kherani, D., Memon, G. M., Karim, A. H., & Sattar, A. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00518 · Cited by 218
Peripheral Nervous System Manifestations Associated with COVID-19
Andalib, S., Biller, J., Napoli, M. D., Moghimi, N., McCullough, L. D., Rubiños, C., Nobleza, C. O., Azarpazhooh, M. R., Catanese, L., Elicer, I., et al. (2021) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-021-01102-5 · Cited by 198
Climate change, environment pollution, COVID-19 pandemic and mental health
Marazziti, D., Cianconi, P., Mucci, F., Crowther, L. F., Chiarantini, I., & Vecchia, A. D. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.145182 · Cited by 204
Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates
Rutkai, I., Mayer, M. G., Hellmers, L., Ning, B., Huang, Z. J., Monjure, C. J., Coyne, C., Silvestri, R., Golden, N., Hensley, K., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-29440-z · Cited by 202
Factors associated with disease severity and mortality among patients with COVID-19: A systematic review and meta-analysis
Chidambaram, V., Tun, N. L., Haque, W. Z., Majella, M. G., Sivakumar, R. K., Kumar, A., Hsu, A. T., Ishak, I. A., Nur, A. A., Ayeh, S. K., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0241541 · Cited by 176
Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19
Shibata, S., Arima, H., Asayama, K., Hoshide, S., Ichihara, A., Ishimitsu, T., Kario, K., Kishi, T., Mogi, M., Nishiyama, A., et al. (2020) · Hypertension Research · doi:10.1038/s41440-020-0515-0 · Cited by 181
COVID-19–Associated Nonocclusive Fibrin Microthrombi in the Heart
Bois, M. C., Boire, N. A., Layman, A. J., Aubry, M.-C., Alexander, M. P., Roden, A. C., Hagen, C. E., Quinton, R. A., Larsen, C. P., Erben, Y., et al. (2020) · Circulation · doi:10.1161/circulationaha.120.050754 · Cited by 163
Neurological Complications of SARS-CoV-2 Infection in Children: A Systematic Review and Meta-Analysis
Panda, P. K., Sharawat, I. K., Panda, P., Natarajan, V., Bhakat, R., & Dawman, L. (2020) · Journal of Tropical Pediatrics · doi:10.1093/tropej/fmaa070 · Cited by 160
Endothelial Dysfunction in COVID-19: Lessons Learned from Coronaviruses
Gavriilaki, E., Anyfanti, P., Gavriilaki, M., Lazaridis, A. A., Δούμα, Σ., & Gkaliagkousi, Ε. (2020) · Current Hypertension Reports · doi:10.1007/s11906-020-01078-6 · Cited by 160
COVID-19-Associated Neurological Disorders: The Potential Route of CNS Invasion and Blood-Brain Barrier Relevance
Achar, A., & Ghosh, C. (2020) · Cells · doi:10.3390/cells9112360 · Cited by 160
COVID-19: Complement, Coagulation, and Collateral Damage
Lo, M. W., Kemper, C., & Woodruff, T. M. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000644 · Cited by 160
Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations
Jha, N. K., Ojha, S. K., Jha, S. K., Dureja, H., Singh, S. K., Shukla, S. D., Chellappan, D. K., Gupta, G., Bhardwaj, S., Kumar, N., et al. (2021) · Journal of Molecular Neuroscience · doi:10.1007/s12031-020-01767-6 · Cited by 154
Review of Current COVID-19 Diagnostics and Opportunities for Further Development
Mardian, Y., Kosasih, H., Karyana, M., Neal, A., & Lau, C. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.615099 · Cited by 153
Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology
Ribeiro, D. E., Oliveira-Giacomelli, Á., Glaser, T., Arnaud-Sampaio, V. F., Andrejew, R., Dieckmann, L., Baranova, J., Lameu, C., Ratajczak, M. Z., & Ulrich, H. (2021) · Molecular Psychiatry · doi:10.1038/s41380-020-00965-3 · Cited by 145
Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology
Deigendesch, N., Sironi, L., Kutza, M., Wischnewski, S., Fuchs, V., Hench, J., Frank, A., Nienhold, R., Mertz, K. D., Cathomas, G., et al. (2020) · Acta Neuropathologica · doi:10.1007/s00401-020-02213-y · Cited by 142
The Impact of SARS‐CoV ‐2 on Stroke Epidemiology and Care: A Meta‐Analysis
Katsanos, A. H., Palaiodimou, L., Zand, R., Yaghi, S. R., Kamel, H., Navi, B. B., Turc, G., Romoli, M., Sharma, V. K., Mavridis, D., et al. (2020) · Annals of Neurology · doi:10.1002/ana.25967 · Cited by 138
Neurologic Characteristics in Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis
Pinzon, R. T., Wijaya, V. O., Buana, R. B., Jody, A. A., & Nunsio, P. N. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00565 · Cited by 133
Neuropsychiatric aspects of COVID-19 pandemic: A selective review
Dinakaran, D., Manjunatha, N., Kumar, C. N., & Suresh, B. M. (2020) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2020.102188 · Cited by 136
Cerebral ischemic and hemorrhagic complications of coronavirus disease 2019
Sweid, A., Hammoud, B., Bekelis, K., Missios, S., Tjoumakaris, S. I., Gooch, M. R., Herial, N. A., Zarzour, H. K., Romo, V. M., DePrince, M., et al. (2020) · International Journal of Stroke · doi:10.1177/1747493020937189 · Cited by 131
Post-COVID 19 neurological syndrome: Implications for sequelae’s treatment
Camargo-Martínez, W., Lozada-Martínez, I. D., Escobar-Collazos, A., Navarro-Coronado, A., Moscote‐Salazar, L. R., Pacheco-Hernández, A., Janjua, T. M., & Bosque‐Varela, P. (2021) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2021.04.001 · Cited by 128
Central Nervous System Manifestations Associated with COVID-19
Divani, A. A., Andalib, S., Biller, J., Napoli, M. D., Moghimi, N., Rubiños, C., Nobleza, C. O., Sylaja, P. N., Toledano, M., Lattanzi, S., et al. (2020) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-020-01079-7 · Cited by 129
Intracerebral haemorrhage and COVID-19: Clinical characteristics from a case series
Benger, M., Williams, O., Siddiqui, J., & Sztriha, L. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.06.005 · Cited by 124
Neurological involvement of coronavirus disease 2019: a systematic review
Ghannam, M., Alshaer, Q., Al-Chalabi, M., Zakarna, L., Robertson, J., & Manousakis, G. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09990-2 · Cited by 119
Neurological Complications Associated with the Blood-Brain Barrier Damage Induced by the Inflammatory Response During SARS-CoV-2 Infection
Alquisiras-Burgos, I., Peralta-Arrieta, I., Alonso-Palomares, L. A., Zacapala-Gómez, A. E., Salmerón-Bárcenas, E. G., & Aguilera, P. (2021) · Molecular Neurobiology · doi:10.1007/s12035-020-02134-7 · Cited by 115
Coronavirus Disease 2019–Associated Coagulopathy
Lippi, G., Sanchis‐Gomar, F., Favaloro, E. J., Lavie, C. J., & Henry, B. M. (2020) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2020.10.031 · Cited by 110
Potential for increased prevalence of neuropathic pain after the COVID-19 pandemic
Attal, N., Martinez, V., & Bouhassira, D. (2021) · PAIN Reports · doi:10.1097/pr9.0000000000000884 · Cited by 107
Cerebrovascular Disease in Patients with COVID-19: A Review of the Literature and Case Series
Reddy, S. T., Garg, T., Shah, C., Nascimento, F. A., Imran, R., Kan, P. T. M., Bowry, R., Gonzales, N. R., Barreto, A. D., Kumar, A., et al. (2020) · Case Reports in Neurology · doi:10.1159/000508958 · Cited by 107
Does COVID‐19 contribute to development of neurological disease?
Mahalakshmi, A. M., Ray, B., Tuladhar, S., Bhat, A., Paneyala, S., Patteswari, D., Sakharkar, M. K., Hamdan, H., Ojcius, D. M., Bolla, S. R., et al. (2020) · Immunity Inflammation and Disease · doi:10.1002/iid3.387 · Cited by 100
Pediatric Ischemic Stroke: An Infrequent Complication of SARS‐CoV ‐2
Beslow, L. A., Linds, A. B., Fox, C. K., Kossorotoff, M., Zambrano, Y. C. Z., Hernández, M., Hassanein, S. M. A., Byrne, S., Lim, M. J., Maduaka, N., et al. (2020) · Annals of Neurology · doi:10.1002/ana.25991 · Cited by 99
COVID‑19 and ischemic stroke: Mechanisms of hypercoagulability (Review)
Zhang, S., Zhang, J., Wang, C., Chen, X., Zhao, X., Jing, H., Liu, H., Li, Z., Wang, L., & Shi, J. (2021) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2021.4854 · Cited by 99
Neurological manifestations and neuro‐invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2
Vonck, K. E. J., Garrez, I., Herdt, V. D., Hemelsoet, D., Laureys, G., Raedt, R., & Boon, P. (2020) · European Journal of Neurology · doi:10.1111/ene.14329 · Cited by 99
Erythropoietin as candidate for supportive treatment of severe COVID-19
Ehrenreich, H., Weißenborn, K., Begemann, M., Busch, M., Vieta, E., & Miskowiak, K. W. (2020) · Molecular Medicine · doi:10.1186/s10020-020-00186-y · Cited by 98
Neuropsychiatric manifestations of COVID-19 and possible pathogenic mechanisms: Insights from other coronaviruses
Banerjee, D., & Viswanath, B. (2020) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2020.102350 · Cited by 100
COVID‐19 as a Blood Clotting Disorder Masquerading as a Respiratory Illness: A Cerebrovascular Perspective and Therapeutic Implications for Stroke Thrombectomy
Janardhan, V., Janardhan, V., & Kalousek, V. (2020) · Journal of Neuroimaging · doi:10.1111/jon.12770 · Cited by 95
Acute Ischemic Stroke During the Convalescent Phase of Asymptomatic COVID-2019 Infection in Men
Tu, T. M., Seet, C. Y. H., Koh, J. S., Tham, C. H., Chiew, H. J., Angon, J., Chua, C. Y. K., Hui, A. C.-F., Tan, S. S. Y., Vasoo, S. S., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.7498 · Cited by 95
A review of pathophysiology and neuropsychiatric manifestations of COVID-19
Jasti, M., Nalleballe, K., Dandu, V., & Onteddu, S. R. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09950-w · Cited by 92
Self-citation
Multisystem Imaging Manifestations of COVID-19, Part 2: From Cardiac Complications to Pediatric Manifestations
Revzin, M. V., Raza, S., Srivastava, N. C., Warshawsky, R., D’Agostino, C. A., Malhotra, A., Bader, A. S., Patel, R. D., Chen, K., Kyriakakos, C., et al. (2020) · Radiographics · doi:10.1148/rg.2020200195 · Cited by 91
Association of Coronavirus Disease (COVID-19) With Large Vessel Occlusion Strokes: A Case-Control Study
Kihira, S., Schefflein, J., Mahmoudi, K., Rigney, B., Delman, B. N., Mocco, J., Doshi, A. H., & Belani, P. B. (2020) · American Journal of Roentgenology · doi:10.2214/ajr.20.23847 · Cited by 89
MRI Brain Findings in 126 Patients with COVID-19: Initial Observations from a Descriptive Literature Review
Gulko, E., Oleksk, M. L., Gomes, W. A., Ali, S., Mehta, H. B., Overby, P. J., Al‐Mufti, F., & Rozenstein, A. (2020) · American Journal of Neuroradiology · doi:10.3174/ajnr.a6805 · Cited by 87
COVID-19 Associated Ischemic Stroke and Hemorrhagic Stroke: Incidence, Potential Pathological Mechanism, and Management
Wang, Z., Yang, Y., Liang, X., Gao, B., Liu, M., Li, W., Chen, Z., & Wang, Z. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.571996 · Cited by 87
Challenges and management of neurological and psychiatric manifestations in SARS-CoV-2 (COVID-19) patients
Orsini, A. A., Corsi, M., Santangelo, A., Riva, A., Peroni, D. G., Foiadelli, T., Savasta, S., & Striano, P. (2020) · Neurological Sciences · doi:10.1007/s10072-020-04544-w · Cited by 86
Cytokine storm induced by SARS-CoV-2 infection: The spectrum of its neurological manifestations
Thepmankorn, P., Bach, J. R., Lasfar, A., Zhao, X., Souayah, S., Chong, Z. Z., & Souayah, N. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155404 · Cited by 89
SARS-CoV-2 and Stroke Characteristics
Shahjouei, S., Tsivgoulis, G. K., Farahmand, G., Koza, E., Mowla, A., Sadr, A. V., Kia, A., Far, A. V., Mondello, S., Cernigliaro, A., et al. (2021) · Stroke · doi:10.1161/strokeaha.120.032927 · Cited by 86
Increased risk of acute stroke among patients with severe COVID‐19: a multicenter study and meta‐analysis
Siepmann, T., Sedghi, A., SIMON, E., Winzer, S., Barlinn, J., de With, K., Mirow, L., Wolz, M., Gruenewald, T., Schroettner, P., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14535 · Cited by 85
THE NERVOUS SYSTEM DAMAGE IN COVID-19 PATIENTS
Викторович, Б. В., Samoilova, E. M., & Baklaushev, V. P. (2020) · Journal of clinical practice · doi:10.17816/clinpract34851 · Cited by 89
Clinical Characteristics of Stroke with COVID-19: A Systematic Review and Meta-Analysis
Yamakawa, M., Kuno, T., Mikami, T., Takagi, H., & Gronseth, G. (2020) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2020.105288 · Cited by 83
Blood Biomarkers for Detection of Brain Injury in COVID-19 Patients
DeKosky, S. T., Kochanek, P. M., Valadka, A. B., Clark, R. S. B., Chou, S., Au, A. K., Horvat, C. M., Jha, R. M., Mannix, R., Wisniewski, S. R., et al. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2020.7332 · Cited by 87
Higher albumin levels on admission predict better prognosis in patients with confirmed COVID-19
Kheir, M. M., Saleem, F., Wang, C., Mann, A. S., & Chua, J. D. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248358 · Cited by 81
The mental health of neurological doctors and nurses in Hunan Province, China during the initial stages of the COVID-19 outbreak
Ning, X., Yu, F., Huang, Q., Li, X., Luo, Y., Huang, Q. M., & Chen, C. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02838-z · Cited by 79
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19.
Prudencio, M., Erben, Y., Marquez, C. P., Jansen-West, K. R., Franco-Mesa, C., Heckman, M. G., White, L. J., Dunmore, J. A., Cook, C. N., Lilley, M. T., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abi7643 · Cited by 78
COVID-19 and Cerebrovascular Diseases: A Systematic Review and Perspectives for Stroke Management
Fraiman, P. H. A., Godeiro-Junior, C. D. O., Moro, E., Cavallieri, F., & Zedde, M. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.574694 · Cited by 78
Neurological involvement in SARS-CoV-2 infection: A clinical systematic review
Scoppettuolo, P., Borrelli, S., & Naeije, G. (2020) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2020.100094 · Cited by 78
Neurological Complications of COVID-19 and Possible Neuroinvasion Pathways: A Systematic Review
Orrù, G., Conversano, C., Malloggi, E., Francesconi, F., Ciacchini, R., & Gemignani, A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186688 · Cited by 78
Descriptive analysis of long COVID sequelae identified in a multidisciplinary clinic serving hospitalised and non-hospitalised patients
Johnsen, S., Sattler, S. M., Miskowiak, K. W., Kunalan, K., Victor, A., Pedersen, L., Andreassen, H. F., Jørgensen, B. J., Heebøll, H., Andersen, M. B., et al. (2021) · ERJ Open Research · doi:10.1183/23120541.00205-2021 · Cited by 80
Heterogeneity in Regional Damage Detected by Neuroimaging and Neuropathological Studies in Older Adults With COVID-19: A Cognitive-Neuroscience Systematic Review to Inform the Long-Term Impact of the Virus on Neurocognitive Trajectories
Manca, R., Marco, M. D., Ince, P. G., & Venneri, A. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.646908 · Cited by 77
COVID-19 Pathophysiology Predicts That Ischemic Stroke Occurrence Is an Expectation, Not an Exception—A Systematic Review
Wijeratne, T., Crewther, S. G., Sales, C., & Karimi, L. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2020.607221 · Cited by 75
Retinal manifestations in patients with SARS-CoV-2 infection and pathogenetic implications: a systematic review
Sen, S., Kannan, N. B., Kumar, J., Rajan, R. P., Kumar, K., Baliga, G., Reddy, H., Upadhyay, A., & Ramasamy, K. (2021) · International Ophthalmology · doi:10.1007/s10792-021-01996-7 · Cited by 75
COVID‐19: Neuroimaging Features of a Pandemic
Ladopoulos, T., Zand, R., Shahjouei, S., Chang, J. J., Motte, J., James, J. C., Katsanos, A. H., Kerro, A., Farahmand, G., Far, A. V., et al. (2021) · Journal of Neuroimaging · doi:10.1111/jon.12819 · Cited by 71
Acute Stroke Presentation, Care, and Outcomes in Community Hospitals in Northern California During the COVID-19 Pandemic
Nguyen‐Huynh, M. N., Tang, X. N., Vinson, D. R., Flint, A. C., Alexander, J., Meighan, M., Burnett, M. M., Sidney, S., & Klingman, J. G. (2020) · Stroke · doi:10.1161/strokeaha.120.031099 · Cited by 64
Neurological manifestations in COVID-19: A narrative review
Rahman, A., Niloofa, R., Zoysa, I. D., Cooray, A., Kariyawasam, J., & Seneviratne, S. L. (2020) · SAGE Open Medicine · doi:10.1177/2050312120957925 · Cited by 64
Central Nervous System Targets and Routes for SARS-CoV-2: Current Views and New Hypotheses
Barrantes, F. J. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00434 · Cited by 65
Characteristics of Large-Vessel Occlusion Associated with COVID-19 and Ischemic Stroke
John, S., Kesav, P., Mifsud, V. A., Piechowski‐Jóźwiak, B., Dibu, J. R., Bayrlee, A., Elkambergy, H., Röser, F., Elhammady, M. S., Zahra, K., et al. (2020) · American Journal of Neuroradiology · doi:10.3174/ajnr.a6799 · Cited by 62
Neurological manifestations of coronavirus disease 2019: exploring past to understand present
Desai, I., Manchanda, R., Kumar, N., Tiwari, A., & Kumar, M. (2021) · Neurological Sciences · doi:10.1007/s10072-020-04964-8 · Cited by 62
COVID-19 and stroke: A review
Qi, X., Keith, K. A., & Huang, J. H. (2020) · Brain Hemorrhages · doi:10.1016/j.hest.2020.11.001 · Cited by 63
Neurological Complications and Noninvasive Multimodal Neuromonitoring in Critically Ill Mechanically Ventilated COVID-19 Patients
Battaglini, D., Santori, G., Chandraptham, K., Iannuzzi, F., Bastianello, M., Tarantino, F., Ball, L., Giacobbe, D. R., Vena, A., Bassetti, M., et al. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.602114 · Cited by 60
In silico Molecular Docking Analysis Targeting SARS-CoV-2 Spike Protein and Selected Herbal Constituents
Anbazhagan, S., Karthikeyan, R., Singh, S. V., Sankar, M., Thomas, P., Dhama, K., Malik, Y. S., Singh, R. K., & Chaudhuri, P. (2020) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.14.spl1.37 · Cited by 58
SARS-CoV-2, More than a Respiratory Virus: Its Potential Role in Neuropathogenesis
Singal, C. M. S., Jaiswal, P., & Seth, P. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00251 · Cited by 59
A Review on the Neurological Manifestations of COVID-19 Infection: a Mechanistic View
Zangbar, H. S., Gorji, A., & Ghadiri, T. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02149-0 · Cited by 57
Neuropathogenesis of SARS-CoV-2 infection
Khan, S., & Gomes, J. (2020) · eLife · doi:10.7554/elife.59136 · Cited by 53
Stroke in Coronavirus Disease 2019: A Systematic Review
Bhatia, R., Pedapati, R., Komakula, S., Srivastava, M. V. P., Vishnubhatla, S., & Khuranac, D. (2020) · Journal of Stroke · doi:10.5853/jos.2020.02264 · Cited by 52
Hospitalizations for Stroke in France During the COVID-19 Pandemic Before, During, and After the National Lockdown
Mariet, A., Giroud, M., Benzenine, É., Cottenet, J., Roussot, A., Aho, S., Tubert‐Bitter, P., Béjot, Y., & Quantin, C. (2021) · Stroke · doi:10.1161/strokeaha.120.032312 · Cited by 52
Cellular mechanisms underlying neurological/neuropsychiatric manifestations of COVID‐19
Bodnar, B. H., Patel, K., Ho, W., Luo, J. J., & Hu, W. (2020) · Journal of Medical Virology · doi:10.1002/jmv.26720 · Cited by 51
Notable Developments for Vitamin D Amid the COVID-19 Pandemic, but Caution Warranted Overall: A Narrative Review
Lordan, R. (2021) · Nutrients · doi:10.3390/nu13030740 · Cited by 50
Stroke Care during the COVID-19 Pandemic: International Expert Panel Review
Venketasubramanian, N., Anderson, C. S., Ay, H., Aybek, S., Brinjikji, W., de Freitas, G. R., Brutto, Ó. H. D., Fassbender, K. C., Fujimura, M., Goldstein, L. B., et al. (2021) · Cerebrovascular Diseases · doi:10.1159/000514155 · Cited by 49
Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019
Cooper, J. G., Stukas, S. K., Hoiland, R. L., Fergusson, N. A., Thiara, S., Foster, D., Mitra, A. R., Stoessl, A. J., Panenka, W. J., Sekhon, M. S., et al. (2020) · Critical Care Explorations · doi:10.1097/cce.0000000000000238 · Cited by 48

Authors: Avula, A., Nalleballe, K., Narula, N., Sapozhnikov, S., Dandu, V., Toom, S., Glaser, A., & Elsayegh, D.
Affiliations: Northwell Health (US)
University of Arkansas for Medical Sciences (US)
Maimonides Medical Center (US)
Corresponding author: Avula, Akshay
ORCID: Avula, Akshay
Nalleballe, Krishna
Narula, Naureen
Toom, Sudhamshi
Glaser, Allison
Venue: Brain, Behavior, and Immunity
Publisher: Elsevier BV
Published: 2020-07
Volume: 87
Pages: 115-119
ISSN: 0889-1591 (ISSN-L)
DOI: 10.1016/j.bbi.2020.04.077
PMC: PMC7187846
OpenAlex: W3018857106
Cited by: 558
References: 23
Citations by year: 2026: 5 · 2025: 1 · 2024: 22 · 2023: 27 · 2022: 78 · 2021: 172 · 2020: 251
FWCI: 57.12
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Brain Behavior and Immunity (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
Keywords: COVID-19 pandemic, SARS-CoV-2, acute stroke, stroke, atypical presentation, neurological symptoms, personal protective equipment, stroke team
MeSH terms: Betacoronavirus, COVID-19, SARS-CoV-2, Aged, Aged, 80 and over, Female, Hospitalization, Humans, Male, Pneumonia, Viral, Retrospective Studies, Coronavirus Infections, Stroke, Pandemics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

COVID-19 presenting as stroke

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks