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Linking atypical depression and insulin resistance-related disorders via low-grade chronic inflammation: Integrating the phenotypic, molecular and neuroanatomical dimensions
Open accessAbstract
Insulin resistance (IR) and related disorders, such as T2DM, increase the risk of major depressive disorder (MDD) and vice versa. Current evidence indicates that psychological stress and overeating can induce chronic low-grade inflammation that can interfere with glutamate metabolism in MDD as well as insulin signaling, particularly in the atypical subtype. Here we first review the interactive role of inflammatory processes in the development of MDD, IR and related metabolic disorders. Next, we describe the role of the anterior cingulate cortex in the pathophysiology of MDD and IR-related disorders. Furthermore, we outline how specific clinical features of atypical depression, such as hyperphagia, are more associated with inflammation and IR-related disorders. Finally, we examine the regional specificity of the effects of inflammation on the brain that show an overlap with the functional and morphometric brain patterns activated in MDD and IR-related disorders.
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“symptoms of increased appetite, energy balance disturbances and hypersomnia, which are shared between atypical MDD and metabolic diseases including obesity, the metabolic syndrome and diabetes mellitus15,257.”
From Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management (2023) · cites this paper as [257]
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Items 201–303 of 303
Wang, Y., Lawson, M. A., Dantzer, R., & Kelley, K. W. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.06.152 · Cited by 92
Association between Impulsivity and Weight Status in a General Population
Bénard, M., Camilleri, G. M., Étilé, F., Méjean, C., Bellisle, F., Reach, G., Herçberg, S., & Péneau, S. (2017) · Nutrients · doi:10.3390/nu9030217 · Cited by 92
Hickman, R. J., Khambaty, T., & Stewart, J. C. (2014) · Journal of Behavioral Medicine · doi:10.1007/s10865-013-9510-0 · Cited by 90
The Role of Astrocytic Glycogen in Supporting the Energetics of Neuronal Activity
DiNuzzo, M., Mangia, S., Maraviglia, B., & Giove, F. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0802-5 · Cited by 89
Dinel, A., André, C., Aubert, A., Ferreira, G., Layé, S., & Castanon, N. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.10.014 · Cited by 89
Serum proteomic profiles of depressive subtypes
Lamers, F., Bot, M., Jansen, R., Chan, M. K., Cooper, J. D., Bahn, S., & Penninx, B. W. J. H. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.115 · Cited by 89
Self-citationFritz, B. M., Muñoz, B., Yin, F., Bauchle, C. J., & Atwood, B. K. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.12.036 · Cited by 88
Gili, M., Roca, M., Armengol, S., Asensio, D., García‐Campayo, J., & Parker, G. B. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048200 · Cited by 87
High serum leptin levels in depressive disorders with atypical features
Geçici, Ö., Kuloğlu, M., Atmaca, M., Tezcan, A. E., Tunckol, H., Emül, H. M., & Üstündağ, B. (2005) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2005.01445.x · Cited by 86
Zheng, H. X., Zheng, Y., Zhao, L., Chen, M., Bai, G., Hu, Y., Hu, W., Yan, Z., & Gao, H. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.11.003 · Cited by 86
Effects of serum brain derived neurotrophic factor on exercise augmentation treatment of depression.
Toups, M. S. P., Greer, T. L., Kurian, B. T., Grannemann, B. D., Carmody, T. J., Huebinger, R., Rethorst, C., & Trivedi, M. H. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.05.002 · Cited by 85
Inadequate brain glycogen or sleep increases spreading depression susceptibility
Kılıç, K., Karataş, H., Dönmez‐Demir, B., Eren‐Koçak, E., Özdemir, Y., Can, A., Petit, J., Magistretti, P. J., & Dalkara, T. (2017) · Annals of Neurology · doi:10.1002/ana.25122 · Cited by 85
Emery, C. F., Fondow, M. D. M., Schneider, C., Christofi, F. L., Hunt, C. K., Busby, A. K., NEEDLEMAN, B. J., Melvin, W. S., & Awad, H. (2007) · Obesity Surgery · doi:10.1007/s11695-007-9140-0 · Cited by 84
Phosphate-Activated Glutaminase and Mitochondrial Glutamine Transport in the Brain
Kvamme, E., Roberg, B., & Torgner, I. A. (2000) · Neurochemical Research · doi:10.1023/a:1007668801570 · Cited by 82
Grundy, A. L., Cotterchio, M., Kirsh, V. A., & Kreiger, N. (2014) · PLoS ONE · doi:10.1371/journal.pone.0099780 · Cited by 82
Brain Metabolic Alterations in Patients with Type 1 Diabetes–Hyperglycemia-Induced Injury
Mäkimattila, S., Malmberg-Céder, K., Häkkinen, A., Vuori, K., Salonen, O. L. M., Summanen, P. A., Yki‐Järvinen, H., Kaste, M., Heikkinen, S., Lundbom, N. M. I., et al. (2004) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/01.wcb.0000143700.15489.b2 · Cited by 82
Na+‐Ca2+ cosignaling in the stimulation of the glucose transporter GLUT1 in cultured astrocytes
Porras, O. H., Ruminot, I., Loaiza, A., & Barros, L. F. (2007) · Glia · doi:10.1002/glia.20589 · Cited by 81
Obesity Comorbidity in Unipolar Major Depressive Disorder
Levitan, R. D., Davis, C., Kaplan, A. S., Arenovich, T., Phillips, D. I. W., & Ravindran, A. V. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.11m07394 · Cited by 81
Role of orexin A signaling in dietary palmitic acid-activated microglial cells
Duffy, C. M., Yuan, C., Wisdorf, L. E., Billington, C. J., Kotz, C. M., Nixon, J. P., & Butterick, T. A. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.08.033 · Cited by 80
Antidepressant use and new‐onset diabetes: a systematic review and meta‐analysis
Bhattacharjee, S., Bhattacharya, R., Kelley, G. A., & Sambamoorthi, U. (2013) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2393 · Cited by 77
Sexually Dimorphic Changes of Hypocretin (Orexin) in Depression
Lu, J., Zhao, J., Balesar, R., Fronczek, R., Zhu, Q.-B., Wu, X.-Y., Hu, S.-H., Bao, A.-M., & Swaab, D. F. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.03.043 · Cited by 77
Pohl, J., Woodside, B. C., & Luheshi, G. N. (2009) · Endocrinology · doi:10.1210/en.2009-0526 · Cited by 74
Glaus, J., Vandeleur, C. L., von Känel, R., Lasserre, A. M., Strippoli, M. F., Gholam‐Rezaee, M., Castelao, E., Marques-Vidal, P. M., Bovet, P., Merikangas, K. R., et al. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2014.07.012 · Cited by 74
Coope, A., Torsoni, A. S., & Velloso, L. A. (2016) · European Journal of Endocrinology · doi:10.1530/eje-15-1065 · Cited by 73
The effect of high-fat diet on rat’s mood, feeding behavior and response to stress
Aslani, S., Vieira, N., Marques, F., Costa, P., Sousa, N., & Palha, J. A. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.178 · Cited by 73
Davies, K. A., Cooper, E., Voon, V., Tibble, J. A., Cercignani, M., & Harrison, N. A. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0790-9 · Cited by 73
Bélanger, M., Allaman, I., & Magistretti, P. J. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07135.x · Cited by 71
Rudolf, S., Greggersen, W., Kahl, K. G., Hüppe, M., & Schweiger, U. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.02.016 · Cited by 71
Raison, C. L., & Miller, A. H. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.194 · Cited by 71
Pan, Y., Hong, Y., Zhang, Q., & Kong, L. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.05.007 · Cited by 70
Kampe, J., Tschöp, M. H., Hollis, J. H., & Oldfield, B. J. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06818.x · Cited by 69
A Neural Circuitry Linking Insulin Resistance to Depressed Mood
Ryan, J. P., Sheu, L. K., Critchley, H. D., & Gianaros, P. J. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31824d0865 · Cited by 68
Antidepressant Use and Diabetes Mellitus Risk: A Meta-Analysis
Yoon, J. M., Cho, E.-G., Lee, H.-K., & Park, S. M. (2013) · Korean Journal of Family Medicine · doi:10.4082/kjfm.2013.34.4.228 · Cited by 66
Do atypical features affect outcome in depressed outpatients treated with citalopram?
Stewart, J. W., McGrath, P. J., D, M. F. M., Wisniewski, S. R., Zisook, S., Cook, I. A., Nierenberg, A. A., Trivedi, M. H., Balasubramani, G. K., Warden, D., et al. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709000182 · Cited by 66
Tsai, S., Wu, H., Chen, P., Chen, Y., Yu, M., Wang, T.-F., Wu, S.-Y., Tzeng, S., & Kuo, Y. (2018) · Brain Research · doi:10.1016/j.brainres.2018.07.017 · Cited by 66
Compartmentation of Lactate Originating from Glycogen and Glucose in Cultured Astrocytes
Sickmann, H. M., Schousboe, A., Fosgerau, K., & Waagepetersen, H. S. (2005) · Neurochemical Research · doi:10.1007/s11064-005-8801-4 · Cited by 65
Role of cytokines in atypical depression
Yoon, H.-K., Kim, Y.-K., Lee, H.-J., Kwon, D.-Y., & Kim, L. (2012) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2011.611894 · Cited by 65
Does exercise improve self-reported sleep quality in non-remitted major depressive disorder?
Rethorst, C. D., Sunderajan, P., Greer, T. L., Grannemann, B. D., Nakonezny, P. A., Carmody, T. J., & Trivedi, M. H. (2012) · Psychological Medicine · doi:10.1017/s0033291712001675 · Cited by 65
Geißler, A., Fründ, R., Schölmerich, J., Feuerbach, S., & Zietz, B. (2003) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-2003-44289 · Cited by 65
Zheng, Y., Yang, Y., Dong, B., Zheng, H. X., Lin, X., Du, Y., Li, X., Zhao, L., & Gao, H. (2016) · Molecular Brain · doi:10.1186/s13041-016-0223-5 · Cited by 65
Rosso, M. E. D., Palumbo, M. L., & Genaro, A. M. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.11.021 · Cited by 64
Martín‐Hernández, D., Tendilla‐Beltrán, H., Madrigal, J. L. M., García‐Bueno, B., Leza, J. C., & Caso, J. R. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1096-7 · Cited by 64
Sickmann, H. M., Waagepetersen, H. S., Schousboe, A., Benie, A. J., & Bouman, S. D. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2011.12.019 · Cited by 62
Differential effects of chronic social stress and fluoxetine on meal patterns in mice
Kumar, J., Chuang, J.-C., Na, E. S., Kuperman, A., Gillman, A. G., Mukherjee, S., Zigman, J. M., McClung, C. A., & Lutter, M. L. (2013) · Appetite · doi:10.1016/j.appet.2012.12.023 · Cited by 58
Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance
Su, W., Wei, P., Gong, H., Liu, Y., Zhang, Y., Lian, Y., Cao, Z., Wu, R., Liu, L., Wang, B., et al. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-017-0985-4 · Cited by 58
The relationship of C‐reactive protein to obesity‐related depressive symptoms: A longitudinal study
Daly, M. (2013) · Obesity · doi:10.1002/oby.20051 · Cited by 57
Disrupted Brain Connectivity Patterns in Patients with Type 2 Diabetes
Cui, Y., Li, S., Gu, H., Hu, Y.-Z., Liang, X.-N., Lu, C., Cai, Y., Wang, C.-X., Yang, Y., & Teng, G. (2016) · American Journal of Neuroradiology · doi:10.3174/ajnr.a4858 · Cited by 57
Weng, H., Chen, J.-H., Pan, Z. Z., & Nie, H. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.07.063 · Cited by 55
Zhang, A., Ajilore, O., Zhan, L., GadElkarim, J., Korthauer, L. E., Yang, S., Leow, A., & Kumar, A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.41 · Cited by 52
The prevalence of atypical features across mood, anxiety, and personality disorders
Posternak, M. A., & Zimmerman, M. A. (2002) · Comprehensive Psychiatry · doi:10.1053/comp.2002.33498 · Cited by 51
Hassenstab, J. J., Sweet, L. H., Parigi, A. D., McCaffery, J. M., Haley, A. P., Demos, K. E., Cohen, R. A., & Wing, R. R. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2011.09.008 · Cited by 51
Nigatu, Y. T., Bültmann, U., & Reijneveld, S. A. (2015) · BMC Public Health · doi:10.1186/s12889-015-1682-9 · Cited by 51
Yang, C., Tiemessen, K. M., Bosker, F. J., Wardenaar, K. J., Lie, J., & Schoevers, R. A. (2018) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2018.05.008 · Cited by 51
González, H. M., & Tarraf, W. (2013) · International Psychogeriatrics · doi:10.1017/s1041610212002062 · Cited by 50
García‐Díaz, D. F., Campión, J., Milagro, F. I., Lomba, A., Marzo, F., & Martínez, J. A. (2007) · Journal of Physiology and Biochemistry · doi:10.1007/bf03165765 · Cited by 49
Schousboe, A., Sickmann, H. M., Walls, A. B., Bak, L. K., & Waagepetersen, H. S. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9171-5 · Cited by 49
Ajilore, O., Narr, K. L., Rosenthal, J., Pham, D. L., Hamilton, L. S., Watari, K. F., Elderkin‐Thompson, V., Darwin, C. H., Toga, A. W., & Kumar, A. (2010) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2010.07.003 · Cited by 49
Altered baseline brain activities before food intake in obese men: A resting state fMRI study
Zhang, B., Tian, D., Yu, C., Zhang, J., Xiao, T., von Deneen, K. M., Zang, Y., Walter, M., & Liu, Y. (2014) · Neuroscience Letters · doi:10.1016/j.neulet.2014.10.020 · Cited by 48
Self-citationAssociation between Major Mood Disorders and the hypocretin receptor 1 gene
Rainero, I., Ostacoli, L., Rubino, E., Gallone, S., Picci, L., Fenoglio, P., Negro, E., Rosso, C., Martino, P. D., Marchi, M., et al. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.10.033 · Cited by 47
Zhao, Y., Zhang, Q., Shao, X., Ouyang, L., Wang, X., Zhu, K., & Chen, L. (2017) · Scientific Reports · doi:10.1038/srep43192 · Cited by 47
Liu, D., Duan, S., Zhou, C., Wei, P., Chen, L., Yin, X., Zhang, J., & Wang, J. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00055 · Cited by 47
Increased Risk of Metabolic Syndrome in Antidepressants Users: A Mini Review
Gramaglia, C. M., Gambaro, E., Bartolomei, G., Paolo Camera, M. D., Chiarelli-Serra, M., Lorenzini, L., & Zeppegno, P. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00621 · Cited by 46
Lee, J. C., Park, S. M., Kim, I. Y., Sung, H., Seong, J. K., & Moon, M. H. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.05.007 · Cited by 43
NAGAMACHI, S., NISHIKAWA, T., ONO, S., KAWASAKI, K., EGUCHI, G., Hoshi, H., JINNOUCHI, S., Ohnishi, T., Futami, S., & Watanabe, K. (1995) · Nuclear Medicine Communications · doi:10.1097/00006231-199501000-00005 · Cited by 42
Li, M., Metzger, C. D., Li, W., Safron, A., van Tol, M., Lord, A., Krause, A. L., Borchardt, V., Dou, W., Genz, A., et al. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.08.001 · Cited by 40
Self-citationThe bipolar-borderline personality disorders connection in major depressive patients
Perugi, G., Angst, J., Azorin, J., Bowden, C. L., Vieta, E., Young, A. H., & The BRIDGE Study Group (2013) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12083 · Cited by 38
Kumar, A., Gupta, R. K., Thomas, A., Ajilore, O., & Hellemann, G. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.548 · Cited by 36
Park, H. Y., Lee, B.-J., Kim, J., Bae, J. N., & Hahm, B. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.11.010 · Cited by 36
Peña, S., Baccichet, E., Urbina, M., Carreira, I., & Lima, L. (2005) · International Immunopharmacology · doi:10.1016/j.intimp.2005.02.005 · Cited by 36
Cano, V., Valladolid‐Acebes, I., Hernández-Nuño, F., Merino, B., Olmo, N. D., Chowen, J. A., & Ruiz‐Gayo, M. (2014) · Neuroreport · doi:10.1097/wnr.0000000000000180 · Cited by 34
Hypothalamic orexin prevents hepatic insulin resistance induced by social defeat stress in mice
Tsuneki, H., Tokai, E., Sugawara, C., Wada, T., Sakurai, T., & Sasaoka, T. (2013) · Neuropeptides · doi:10.1016/j.npep.2013.02.002 · Cited by 34
Rethorst, C. D., Tu, J., Carmody, T. J., Greer, T. L., & Trivedi, M. H. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.01.052 · Cited by 33
Hong, G., Gao, P., Chen, Y., Xia, Y. Y., Ke, X., Shao, X., Xiong, C., Chen, H.-S., Xiao, H., Ning, J., et al. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s241774 · Cited by 33
High fat diet induces specific pathological changes in hypothalamic orexin neurons in mice
Nobunaga, M., Obukuro, K., Kurauchi, Y., Hisatsune, A., Seki, T., Tsutsui, M., & Katsuki, H. (2014) · Neurochemistry International · doi:10.1016/j.neuint.2014.09.002 · Cited by 32
Physical exercise ameliorates mood disorder-like behavior on high fat diet-induced obesity in mice
Park, H.-S., Lee, J. M., Cho, H.-S., Park, S.-S., & Kim, T.-W. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.01.012 · Cited by 31
Fugger, G., Dold, M., Bartova, L., Kautzky, A., Souery, D., Mendlewicz, J., Serretti, A., Zohar, J., Montgomery, S., Frey, R., et al. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109638 · Cited by 30
Prefrontal myo-inositol concentration and visuospatial functioning among diabetic depressed patients
Haroon, E., Watari, K. F., Thomas, A., Ajilore, O., Mintz, J., Elderkin‐Thompson, V., Darwin, C. H., Kumaran, S. S., & Kumar, A. A. (2008) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2008.03.006 · Cited by 28
Yang, C., Shen, J., Hong, T., Hu, T., Li, Z.-J., Zhang, H., ZHANG, Y.-J., Zhou, Z., & Yang, J. (2013) · Molecular Medicine Reports · doi:10.3892/mmr.2013.1600 · Cited by 28
Kitagawa, Y., Nakaso, K., Horikoshi, Y., Morimoto, M., Omotani, T., Otsuki, A., Inagaki, Y., Sato, H., & Matsura, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-44006-8 · Cited by 28
Raffield, L. M., Brenes, G. A., Cox, A. J., Freedman, B. I., Hugenschmidt, C. E., Hsu, F., Xu, J., Wagner, B., Williamson, J. D., Maldjian, J. A., et al. (2015) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2015.09.010 · Cited by 27
Persson, M., Brantefjord, M., Liljeqvist, J., Bergström, T. B., Hansson, E., & Rönnbäck, L. (2007) · Glia · doi:10.1002/glia.20560 · Cited by 27
Eser, H. Y., Dönmez‐Demir, B., Kılıç, K., Eren‐Koçak, E., & Dalkara, T. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.05.024 · Cited by 27
Xia, W., Luo, Y., Chen, Y., Zhang, D., Bo, F., Zhou, P., Chen, H., Wang, F., Yin, X., & Ma, J. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.12.012 · Cited by 26
Involvement of inflammatory gene expression pathways in depressed patients with hyperphagia
de Kluiver, H., Jansen, R., Milaneschi, Y., & Penninx, B. W. J. H. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0528-0 · Cited by 26
Mortality Associated with Major Depression in a Canadian Community Cohort
Patten, S. B., Williams, J. V. A., Lavorato, D. H., Wang, J., Khaled, S. M., & Bulloch, A. G. (2011) · The Canadian Journal of Psychiatry · doi:10.1177/070674371105601104 · Cited by 25
Neuroanatomical correlates of executive functioning in depressed adults with type 2 diabetes
Watari, K. F., Elderkin‐Thompson, V., Ajilore, O., Haroon, E., Darwin, C. H., Pham, D. L., & Kumar, A. (2008) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390701440486 · Cited by 25
Cerebral Glucose Metabolism in Type 1 Diabetic Patients
Ziegler, D., Langen, K., Herzog, H. R., Kuwert, T., Mühlen, H., Feinendegen, L. E., & Gries, F. A. (1994) · Diabetic Medicine · doi:10.1111/j.1464-5491.1994.tb02021.x · Cited by 25
Desmidt, T., Hachemi, M. E., Réméniéras, J.-P., Lecomte, P., Ferreira-Maldent, N., Patat, F., & Camus, V. (2011) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2011.01.002 · Cited by 24
Regional cerebral hypoperfusion in long-term Type 1 (insulin-dependent) diabetic patients
Keymeulen, B., JACOBS, A., Metz, K. D., Sadeleer, C. D., Bossuyt, A. M., & Somers, G. (1995) · Nuclear Medicine Communications · doi:10.1097/00006231-199501000-00004 · Cited by 23
Obesity is associated with hypothalamic injury in rodents and humans
Thaler, J. P., Yi, C., Schur, E. A., Guyenet, S. J., Hwang, B. H., Dietrich, M. O., Zhao, X., Sarruf, D. A., Izgur, V., Maravilla, K. R., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci62813 · Cited by 23
Rodgers, S., Vandeleur, C. L., Ajdacic‐Gross, V., Aleksandrowicz, A., Strippoli, M. F., Castelao, E., Glaus, J., Lasserre, A. M., Müller, M., Wulf Rössler, A., et al. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.10.067 · Cited by 22
Testing DSM-IV Definition of Atypical Depression
Benazzi, F. (2003) · Annals of Clinical Psychiatry · doi:10.1023/a:1023272408562 · Cited by 20
Liu, X., & Zheng, H. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01217 · Cited by 20
Tsai, S., Chen, Y., & Kuo, Y. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.10.024 · Cited by 19
Modulation of attention network activation under antidepressant agents in healthy subjects
Graf, H., Abler, B., Hartmann, A., Metzger, C. D., & Walter, M. (2012) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145712001368 · Cited by 17
Self-citationLiu, D., Chen, L., Duan, S., Yin, X., Yang, W. C., Shi, Y., Zhang, J., & Wang, J. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00875 · Cited by 17
Phillips, O. R., Onopa, A., Zaiko, Y. V., & Singh, M. K. (2018) · Pediatric Diabetes · doi:10.1111/pedi.12672 · Cited by 14
Whale, R., Fialho, R., Field, A. P., Campbell, G. R., Tibble, J. A., Harrison, N. A., & Rolt, M. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.04.035 · Cited by 14
Testing DSM-IV Definition of Atypical Depression
Benazzi, F. (2003) · Annals of Clinical Psychiatry · doi:10.3109/10401230309085665 · Cited by 12
Disassociation of verbal learning and hippocampal volume in type 2 diabetes and major depression
Ajilore, O., Lamar, M., Medina, J., Watari, K. F., Elderkin‐Thompson, V., & Kumar, A. A. (2014) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4149 · Cited by 11
Psychobiology of the intersection and divergence of depression and anxiety
Pizzagalli, D. A. (2016) · Depression and Anxiety · doi:10.1002/da.22550 · Cited by 11
Biophysical changes in subcortical nuclei: the impact of diabetes and major depression
Kumar, A., Yang, S., Ajilore, O., Wu, M., Cohen, J., Lamar, M., & Bhaumik, D. K. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.89 · Cited by 7
Revisiting the Association Between Metabolic Syndrome and Depressive Symptoms
Kobrosly, R. W., & van Wijngaarden, E. (2010) · Annals of Epidemiology · doi:10.1016/j.annepidem.2010.08.002 · Cited by 6
Flagged first, then by citations
2 of the 305 references couldn’t be matched to a known paper.
Research works printed but not linked: 7
- Karlović, 2012, Serum concentrations of CRP, IL-6, TNF-$\alpha{\$}and cortisol in major depressive disorder with melancholic or atypical features, Psychiatry Res., 198, 74, 10.1016/j.psychres.2011.12.007 · DOI · Paper page
- Martinez-Hernandez, 1977, Glutamine synthetase: Glial localization in brain. Science (80-), [Internet]., 195, 1356
- Milaneschi, 2020, Feb 3, Available from:
- Palomero-Gallagher N, Vogt BA. The Human Nervous System. 3rd edition 2012. In: Juergen K Mai, Paxinos G, editors The Human Nervous System 3rd edition 2012. 2012. p. N. Cingulate gyrus. pp. 943-987.
- Palomero-Gallagher, 2009, Receptor architecture of human cingulate cortex: Evaluation of the four-region neurobiological model, Hum. Brain Mapp., 10.1002/hbm.20667 · DOI
- Ding, 2019, Altered interactions among resting state networks in obese individuals, Obesity
- Peng, 2016, Atypical features and bipolar disorder. Shanghai Arch, Psychiatry.
Cited by
Sorted by citations
Berk, M., Köhler‐Forsberg, O., Turner, M., Penninx, B. W. J. H., Wrobel, A., Firth, J., Loughman, A., Reavley, N. J., McGrath, J. J., Momen, N. C., et al. (2023) · World Psychiatry · doi:10.1002/wps.21110 · Cited by 336
Chlorogenic Acid-Induced Gut Microbiota Improves Metabolic Endotoxemia
Ye, X., Liu, Y., Hu, J., Gao, Y., Ma, Y., & Wen, D. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.762691 · Cited by 145
Update on the Relationship Between Depression and Neuroendocrine Metabolism
Qiu, W., Cai, X., Zheng, C., Qiu, S., Ke, H., & Huang, Y. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.728810 · Cited by 90
Insulin resistance: The role in comorbid type 2 diabetes mellitus and depression
Yao, J., Zhu, C., Sun, Y., Huang, Y., Li, Q., Liao, H.-M., Deng, X.-J., & Li, W.-M. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106218 · Cited by 45
Insulin resistance as a marker for the immune-metabolic subtype of depression
Brouwer, A., van Raalte, D. H., Lamers, F., Rutters, F., Elders, P. J. M., Someren, E. J. W. V., Snoek, F. J., Beekman, A. T. F., & Bremmer, M. A. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.08.151 · Cited by 35
Self-citation
Metadata
- Authors
- Sen, Z. D., Danyeli, L. V., Woelfer, M., Lamers, F., Wagner, G., Sobanski, T., & Walter, M.
- Affiliations
- Jena University Hospital (DE)
- Leibniz Institute for Neurobiology (DE)
- Amsterdam University Medical Centers (NL)
- Corresponding author
- Walter, Martin
- Venue
- Brain, Behavior, and Immunity
- Publisher
- Elsevier BV
- Published
- 2021-03
- Volume
- 93
- Pages
- 335-352
- ISSN
- 0889-1591 (ISSN-L)
- OpenAlex
- W3114780798
- Cited by
- 65
- References
- 305
- Citations by year
- 2026: 12 · 2025: 22 · 2024: 9 · 2023: 11 · 2022: 4 · 2021: 6
- FWCI
- 0.43
- Type
- journal article
- Language
- en
- Open access
- green
- research.vumc.nl
- Licence
- Locations
- Brain Behavior and Immunity (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
- Pure Amsterdam UMC (submittedVersion, cc-by)
- Informationszentrum Lebenswissenschaften (ZB MED) (submittedVersion, cc-by-nc-nd)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- Horizon 2020
- Deutsche Forschungsgemeinschaft
- Topics
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- atypical depression, insulin resistance, low-grade inflammation, major depressive disorder, type 2 diabetes, hyperphagia, anterior cingulate cortex, glutamate metabolism, insulin signaling, psychological stress, neuroinflammation, brain morphometry
- MeSH terms
- Depression, Major Depressive Disorder, Humans, Inflammation, Insulin, Insulin Resistance
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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