Interaction of raclopride and preparatory interval effects on simple reaction time performance

MacDonald, Christopher J.; Meck, Warren H.

doi:10.1016/j.bbr.2006.08.004

Cited by 44Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorNeuroscience and Music Perception

Interaction of raclopride and preparatory interval effects on simple reaction time performance

MacDonald, Christopher J., Meck, Warren H.·2006·Behavioural Brain Research

DOI 10.1016/j.bbr.2006.08.004

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Abstract

In a series of three experiments, simple reaction time (RT) was characterized with respect to a variable preparatory interval (PI) in order to investigate the relationship between interval timing and RT. In Experiment 1, it was shown that RT decreases as a function of PI and that this effect varies with amount of training. In Experiment 2, RT was shown to increase during probe trials that used a novel 6.25s PI, suggesting that the specific durations of the PIs encoded during initial training contribute to the PI effect on RT. In Experiment 3, 100 microg/kg i.p. of raclopride proportionally slowed RT as a function of the PI. These results are discussed within the context of neuropsychological models of interval timing and support an underlying role for cortico-striatal dopaminergic function in temporal processing and simple RT measurements.

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Allman, M. J., Teki, S., Griffiths, T. D., & Meck, W. H. (2013) · Annual Review of Psychology · doi:10.1146/annurev-psych-010213-115117 · Cited by 388 · see citing works
Cortico-striatal representation of time in animals and humans
Meck, W. H., Penney, T. B., & Pouthas, V. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.08.002 · Cited by 368 · see citing works
Neuroanatomical localization of an internal clock: A functional link between mesolimbic, nigrostriatal, and mesocortical dopaminergic systems
Meck, W. H. (2006) · Brain Research · doi:10.1016/j.brainres.2006.06.031 · Cited by 355 · see citing works
Contingent negative variation and its relation to time estimation: a theoretical evaluation
van Rijn, H., Kononowicz, T. W., Meck, W. H., Ng, K. K., & Penney, T. B. (2011) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2011.00091 · Cited by 177 · see citing works
Oscillatory multiplexing of neural population codes for interval timing and working memory
Gu, B.-M., van Rijn, H., & Meck, W. H. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.10.008 · Cited by 155 · see citing works
Differential effects of cocaine and ketamine on time estimation: Implications for neurobiological models of interval timing
CHENG, R., MacDonald, C. J., & Meck, W. H. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.07.019 · Cited by 153 · see citing works
Subjective Time
(2014) · The MIT Press eBooks · doi:10.7551/mitpress/8516.001.0001 · Cited by 144 · see citing works
Differential effects of amphetamine and haloperidol on temporal reproduction: Dopaminergic regulation of attention and clock speed
Lake, J. I., & Meck, W. H. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.09.014 · Cited by 125 · see citing works
Frontal cortex lesions eliminate the clock speed effect of dopaminergic drugs on interval timing
Meck, W. H. (2006) · Brain Research · doi:10.1016/j.brainres.2006.06.046 · Cited by 109 · see citing works
Ketamine “unlocks” the reduced clock-speed effects of cocaine following extended training: Evidence for dopamine–glutamate interactions in timing and time perception
Cheng, R., Ali, Y. M., & Meck, W. H. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.04.005 · Cited by 98 · see citing works
Timing Deficits in Aging and Neuropathology
Balcı, F., Meck, W. H., Moore, H. M., & Brunner, D. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-422-3_8 · Cited by 86 · see citing works
Dopamine and the interdependency of time perception and reward
Fung, B. J., Sutlief, E., & Shuler, M. G. H. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.030 · Cited by 79 · see citing works
Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice
Meck, W. H., Cheng, R., MacDonald, C. J., Gainetdinov, R. R., Caron, M. G., & Çevik, M. Ö. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.01.042 · Cited by 76 · see citing works
Unwinding the Molecular Basis of Interval and Circadian Timing
Agostino, P. V., Golombek, D. A., & Meck, W. H. (2011) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2011.00064 · Cited by 73 · see citing works
Habit formation and the loss of control of an internal clock: inverse relationship between the level of baseline training and the clock-speed enhancing effects of methamphetamine
Cheng, R., Hakak, O. L., & Meck, W. H. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0783-2 · Cited by 70 · see citing works
Acquisition of “Start” and “Stop” response thresholds in peak-interval timing is differentially sensitive to protein synthesis inhibition in the dorsal and ventral striatum
MacDonald, C. J., Cheng, R., & Meck, W. H. (2012) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2012.00010 · Cited by 67 · see citing works
Timing in reward and decision processes
Bermúdez, M. A., & Schultz, W. (2014) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0468 · Cited by 53 · see citing works
“Speed” Warps Time: Methamphetamines Interactive Roles in Drug Abuse, Habit Formation, and the Biological Clocks of Circadian and Interval Timing
Williamson, L. L., Cheng, R., Etchegaray, M., & Meck, W. H. (2008) · Current Drug Abuse Reviews · doi:10.2174/1874473710801020203 · Cited by 50 · see citing works
Impairments in timing, temporal memory, and reversal learning linked to neurotoxic regimens of methamphetamine intoxication
Cheng, R., Etchegaray, M., & Meck, W. H. (2007) · Brain Research · doi:10.1016/j.brainres.2007.10.002 · Cited by 46 · see citing works
Quinpirole-induced sensitization to noisy/sparse periodic input: temporal synchronization as a component of obsessive-compulsive disorder
Gu, B.-M., Cheng, R., Yin, B., & Meck, W. H. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.01.048 · Cited by 43 · see citing works
Dissociations between interval timing and intertemporal choice following administration of fluoxetine, cocaine, or methamphetamine
Heilbronner, S. R., & Meck, W. H. (2013) · Behavioural Processes · doi:10.1016/j.beproc.2013.09.013 · Cited by 38 · see citing works
Bayesian Models of Interval Timing and Distortions in Temporal Memory as a Function of Parkinson’s Disease and Dopamine-Related Error Processing
Gu, B.-M., Jurkowski, A. J., Lake, J. I., Malapani, C., & Meck, W. H. (2015) · BRILL eBooks · doi:10.1163/9789004230699_012 · Cited by 36 · see citing works
Bayesian Optimization of Interval Timing and Biases in Temporal Memory as a Function of Temporal Context, Feedback, and Dopamine Levels in Young, Aged and Parkinson’s Disease Patients
Gu, B.-M., Jurkowski, A. J., Shi, Z., & Meck, W. H. (2016) · Timing & Time Perception · doi:10.1163/22134468-00002072 · Cited by 30 · see citing works
Movement-Contingent Time Flow in Virtual Reality Causes Temporal Recalibration
Bansal, A., Weech, S., & Barnett‐Cowan, M. (2019) · Scientific Reports · doi:10.1038/s41598-019-40870-6 · Cited by 31 · see citing works
Affect in the eyes: explicit and implicit evaluations
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Time in the Psychopathological Mind
Allman, M. J., Yin, B., & Meck, W. H. (2014) · The MIT Press eBooks · doi:10.7551/mitpress/8516.003.0042 · Cited by 24 · see citing works
Impact of Vestibular Lesions on Allocentric Navigation and Interval Timing: The Role of Self-Initiated Motion in Spatial-Temporal Integration
Dallal, N. L., Yin, B., Nekovářová, T., Stuchlı́k, A., & Meck, W. H. (2015) · Timing & Time Perception · doi:10.1163/22134468-03002053 · Cited by 23 · see citing works
Dopamine D1 and D2 antagonist effects on response likelihood and duration.
Choi, W. Y., Morvan, C. I., Balsam, P. D., & Horvitz, J. C. (2009) · Behavioral Neuroscience · doi:10.1037/a0017702 · Cited by 23 · see citing works
Time Distortion in Parkinsonism
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Interval‐timing Protocols and Their Relevancy to the Study of Temporal Cognition and Neurobehavioral Genetics
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Time-Based Expectancy for Task Relevant Stimulus Features
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Setting the beat of an internal clock: Effects of dexamphetamine on different interval ranges of temporal processing in healthy volunteers
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Oscillation/Coincidence-Detection Models of Reward-Related Timing in Corticostriatal Circuits
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Continuous Social Defeat Induces Depression-Like Symptoms Including Anhedonia and Slowed Time Perception that are Rapidly Reversed by Ketamine
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Warren H. MeckNovember 17, 1956–January 21, 2020
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Authors: MacDonald, C. J., & Meck, W. H.
Affiliations: Duke University (US)
Corresponding author: Meck, Warren H.
ORCID: MacDonald, Christopher J.
Meck, Warren H.
Venue: Behavioural Brain Research
Publisher: Elsevier BV
Published: 2006-11
Volume: 175
Issue: 1
Pages: 62-74
ISSN: 0166-4328 (ISSN-L)
DOI: 10.1016/j.bbr.2006.08.004
OpenAlex: W2056279822
Cited by: 44
References: 105
Citations by year: 2022: 1 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 4 · 2015: 2 · 2014: 6 · 2013: 2 · 2012: 2
FWCI: 1.78
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Behavioural Brain Research (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
Keywords: raclopride, simple reaction time, preparatory period, interval timing, dopamine, striatum, temporal processing, probe trials, training effects
MeSH terms: Animals, Attention, Behavior, Animal, Male, Movement, Psychomotor Performance, Reaction Time, Time Factors, Time Perception, Rats, Sprague-Dawley, Dopamine Antagonists, Raclopride, Rats

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Interaction of raclopride and preparatory interval effects on simple reaction time performance

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