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Antioxidants: Molecules, medicines, and myths
Abstract
There is an industry-driven public obsession with antioxidants, which are equated to safe, health-giving molecules to be swallowed as mega-dose supplements or in fortified foods. Sometimes they are good for you, but sometimes they may not be, and pro-oxidants can be better for you in some circumstances. This article re-examines and challenges some basic assumptions in the nutritional antioxidant field.
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“The use of antioxidants has been markedly ineffective when not damaging (97, 390, 400, 785).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [390]
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Metadata
- Authors
- Gutteridge, J. M. C., & Halliwell, B.
- Affiliations
- National University of Singapore (SG)
- Corresponding author
- Halliwell, Barry
- ORCID
- Halliwell, Barry
- Venue
- Biochemical and Biophysical Research Communications
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 393
- Issue
- 4
- Pages
- 561-564
- ISSN
- 0006-291X (ISSN-L)
- OpenAlex
- W1970851794
- Cited by
- 405
- References
- 38
- Citations by year
- 2026: 9 · 2025: 13 · 2024: 8 · 2023: 15 · 2022: 18 · 2021: 22 · 2020: 23 · 2019: 17 · 2018: 30 · 2017: 25 · 2016: 34 · 2015: 39 · 2014: 43 · 2013: 37 · 2012: 39
- FWCI
- 3.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochemical and Biophysical Research Communications (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Keywords
- antioxidants, antioxidant supplements, pro-oxidants, oxidative stress, dietary antioxidants, health claims, fortified foods
- MeSH terms
- Antioxidants, Humans, Oxidation-Reduction, Vitamins, Reactive Oxygen Species, Dietary Supplements
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