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Secreted type of amyloid precursor protein induces glial differentiation by stimulating the BMP/Smad signaling pathway

Kwak, Young-Don, Hendrix, Brandon J., Sugaya, Kiminobu·2014·Biochemical and Biophysical Research Communications
DOI 10.1016/j.bbrc.2014.03.139
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  • Treatment of human neural stem cells with secreted APPα or overexpression of APP promoted phosphorylation of SMAD 1/5/8 and induced massive glial differentiation through the BMP pathway.

    “Furthermore, Kwak, Lohuizen, and colleagues showed that treatment of human neural stem cells with secreted APPα or overexpression of APP promoted phosphorylation of SMAD 1/5/8 and induced massive glial differentiation (by expression of GFAP) through the BMP pathway (Kwak et al., 2014).”

    From Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model (2022) · cites this paper as Kwak et al., 2014

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Research works printed but not linked: 37

  1. Bonaguidi, 2005, LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells, Development, 132, 5503, 10.1242/dev.02166 · DOI
  2. Bonaguidi, 2008, Noggin expands neural stem cells in the adult hippocampus, J. Neurosci., 28, 9194, 10.1523/JNEUROSCI.3314-07.2008 · DOI
  3. Carro, 2001, Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy, J. Neurosci., 21, 5678, 10.1523/JNEUROSCI.21-15-05678.2001 · DOI · Paper page
  4. Cate, 2010, Modulation of bone morphogenic protein signaling alters numbers of astrocytes and oligodendroglia in the subventricular zone during cuprizone-induced demyelination, J. Neurochem., 115, 11, 10.1111/j.1471-4159.2010.06660.x · DOI
  5. Chen, 2009, Cell Death Differ., 16, 386, 10.1038/cdd.2008.94 · DOI · Paper page
  6. Fan, 2004, A combined in situ hybridization and RT-PCR method to detect spatial and temporal patterns of Noggin gene expression in embryonic and postnatal rat hippocampus, Brain Res. Brain Res. Protoc., 13, 99, 10.1016/j.brainresprot.2004.01.005 · DOI
  7. Fukuda, 2006, Roles of BMP in the development of the central nervous system, Clin. Calcium, 16, 781
  8. Gobeske, 2009, BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice, PLoS One, 4, 7506, 10.1371/journal.pone.0007506 · DOI
  9. Gross, 1996, Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells, Neuron, 17, 595, 10.1016/S0896-6273(00)80193-2 · DOI
  10. Haass, 1999, The presenilins in Alzheimer’s disease – proteolysis holds the key, Science, 286, 916, 10.1126/science.286.5441.916 · DOI · Paper page
  11. Hagg, 2005, Molecular regulation of adult CNS neurogenesis: an integrated view, Trends Neurosci., 28, 589, 10.1016/j.tins.2005.08.009 · DOI
  12. Hilbich, 1993, Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11, J. Biol. Chem., 268, 26571, 10.1016/S0021-9258(19)74350-6 · DOI · Paper page
  13. Kim, 2010, Bone morphogenetic protein 4 stimulates attachment of neurospheres and astrogenesis of neural stem cells in neurospheres via phosphatidylinositol 3 kinase-mediated upregulation of N-cadherin, Neuroscience, 170, 8, 10.1016/j.neuroscience.2010.07.020 · DOI
  14. Kwak, 2006, Amyloid precursor protein regulates differentiation of human neural stem cells, Stem Cells Dev., 15, 381, 10.1089/scd.2006.15.381 · DOI
  15. Kwak, 2006, Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells, Biochem. Biophys. Res. Commun., 344, 431, 10.1016/j.bbrc.2006.03.054 · DOI
  16. Kwak, 2010, Amyloid-β precursor protein induces glial differentiation of neural progenitor cells by activation of the IL-6/gp130 signaling pathway, Neurotox. Res., 18, 328, 10.1007/s12640-010-9170-6 · DOI
  17. Kwak, 2011, Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation, Eur. J. Pharmacol., 650, 18, 10.1016/j.ejphar.2010.09.015 · DOI
  18. Lim, 2000, Noggin antagonizes BMP signaling to create a niche for adult neurogenesis, Neuron, 28, 713, 10.1016/S0896-6273(00)00148-3 · DOI
  19. Liu, 2004, SVZa neural stem cells differentiate into distinct lineages in response to BMP4, Exp. Neurol., 190, 109, 10.1016/j.expneurol.2004.07.015 · DOI
  20. López-Toledano, 2007, Increased neurogenesis in young transgenic mice overexpressing human APP(Sw, Ind), J. Alzheimers Dis., 12, 229, 10.3233/JAD-2007-12304 · DOI
  21. Ma, 2005, Glial influences on neural stem cell development: cellular niches for adult neurogenesis, Curr. Opin. Neurobiol., 15, 514, 10.1016/j.conb.2005.08.003 · DOI
  22. Massagué, 2000, Controlling TGF-beta signaling, Genes Dev., 14, 627, 10.1101/gad.14.6.627 · DOI
  23. Mehler, 2000, Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineage fate, Dev. Neurosci., 22, 74, 10.1159/000017429 · DOI
  24. Nakashima, 2002, Mechanisms underlying cytokine-mediated cell-fate regulation in the nervous system, Mol. Neurobiol., 25, 233, 10.1385/MN:25:3:233 · DOI
  25. Nohno, 1995, Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors, J. Biol. Chem., 270, 22522, 10.1074/jbc.270.38.22522 · DOI
  26. Price, 1998, Alzheimer disease – when and why?, Nat. Genet., 19, 314, 10.1038/1196 · DOI
  27. Selkoe, 2001, Alzheimer’s disease: genes, proteins, and therapy, Physiol. Rev., 81, 741, 10.1152/physrev.2001.81.2.741 · DOI · Paper page
  28. Selkoe, 1996, The role of APP processing and trafficking pathways in the formation of amyloid beta-protein, Ann. N.Y. Acad. Sci., 777, 57, 10.1111/j.1749-6632.1996.tb34401.x · DOI · Paper page
  29. Vrostos, 2009, MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling, Brain Res. Bull., 79, 97, 10.1016/j.brainresbull.2009.01.004 · DOI
  30. Boekhoorn, 2006, Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus, Neurobiol. Dis., 24, 1, 10.1016/j.nbd.2006.04.017 · DOI
  31. Lee, 1986, Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins, J. Neurosci., 6, 514, 10.1523/JNEUROSCI.06-02-00514.1986 · DOI
  32. Pleasure, 1993, NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell, J. Neurosci. Res., 35, 585, 10.1002/jnr.490350603 · DOI
  33. Langlois, 1997, Differentiation of the human NT2 cells into neurons or glia, Methods Cell Sci., 19, 213, 10.1023/A:1009731707443 · DOI
  34. Bani-Yaghoub, 1999, Human NT2/D1 cells differentiate into functional astrocytes, Neuroreport, 10, 3843, 10.1097/00001756-199912160-00022 · DOI
  35. Ferrari, 2000, Immature human NT2 cells grafted into mouse brain differentiate into neuronal and glial cell types, FEBS Lett., 486, 121, 10.1016/S0014-5793(00)02251-1 · DOI
  36. Sandhu, 2002, Characterization of astrocytes derived from human NTera-2/D1 embryonal carcinoma cells, J. Neurosci. Res., 68, 604, 10.1002/jnr.10236 · DOI
  37. Kwak, 2006, Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells, Biochem. Biophys. Res. Commun., 344, 431, 10.1016/j.bbrc.2006.03.054 · DOI

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Metadata

Authors
Kwak, Y.-D., Hendrix, B. J., & Sugaya, K.
Venue
Biochemical and Biophysical Research Communications
Publisher
Elsevier BV
Published
2014-05
Volume
447
Issue
3
Pages
394-399
ISSN
0006-291X
DOI
10.1016/j.bbrc.2014.03.139
Cited by
24
References
1
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
  • NIH (R01AG 23472)
  • Alzheimer’s Association (IIRG-03-5577)

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