Circulating Insulin-Like Growth Factor I Mediates the Protective Effects of Physical Exercise against Brain Insults of Different Etiology and Anatomy

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,501 · see citing works

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

van Praag, H., Kempermann, G., & Gage, F. H. (1999) · Nature Neuroscience · doi:10.1038/6368 · Cited by 3,880 · see citing works

The Neuroendocrinology of Stress: A Never Ending Story

Lightman, S. L. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01711.x · Cited by 3,570 · see citing works

Calbindin D-28k and parvalbumin in the rat nervous system

Celio, M. R. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90091-h · Cited by 2,086 · see citing works

Ageing, fitness and neurocognitive function

Kramer, A. F., Hahn, S., Cohen, N. J., Banich, M. T., McAuley, E., Harrison, C. R., Chason, J., Vakil, E., Bardell, L., Boileau, R. A., et al. (1999) · Nature · doi:10.1038/22682 · Cited by 1,394 · see citing works

Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats.

Black, J. E., Isaacs, K. R., Anderson, B. J., Alcantara, A. A., & Greenough, W. T. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.14.5568 · Cited by 1,161 · see citing works

Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus

Trejo, J. L., Carro, E., & Torres-Alemán, I. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-05-01628.2001 · Cited by 1,017 · see citing works

Circulating Insulin-Like Growth Factor I Mediates Effects of Exercise on the Brain

Carro, E., Nuñez, A., Busiguina, S., & Torres-Aleman, I. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-08-02926.2000 · Cited by 762 · see citing works

Insulin induces transcription of target genes through the hypoxia‐inducible factor HIF‐1α/ARNT

Zelzer, E., Levy, Y., Kahana, C., Shilo, B., Rubinstein, M., & Cohen, B. (1998) · The EMBO Journal · doi:10.1093/emboj/17.17.5085 · Cited by 575 · see citing works

Energetics in the pathogenesis of neurodegenerative diseases

Beal, M. F. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01584-8 · Cited by 472 · see citing works

Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene

Airaksinen, M. S., Eilers, J., Garaschuk, O., Thoenen, H., Konnerth, A., & Meyer, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.4.1488 · Cited by 392 · see citing works

Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1

Lin, X., Antalffy, B., Kang, D., Orr, H. T., & Zoghbi, H. Y. (2000) · Nature Neuroscience · doi:10.1038/72101 · Cited by 374 · see citing works

Regular exercise improves cognitive function and decreases oxidative damage in rat brain

Radak, Z. O., Kaneko, T., Tahara, S., Nakamoto, H., Pucsok, J. M., Sasvári, M., Nyakas, C. J., & Goto, S. (2001) · Neurochemistry International · doi:10.1016/s0197-0186(00)00063-2 · Cited by 373 · see citing works

Mechanisms of Angiogenesis in the Brain

Plate, K. H. (1999) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199904000-00001 · Cited by 355 · see citing works

Improving cognitive function after brain injury: The use of exercise and virtual reality

Grealy, M., Johnson, D. A., & Rushton, S. K. (1999) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/s0003-9993(99)90169-7 · Cited by 354 · see citing works

Genetic Classification of Primary Neurodegenerative Disease

Hardy, J., & Gwinn, K. A. (1998) · Science · doi:10.1126/science.282.5391.1075 · Cited by 341 · see citing works

Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1

Sonntag, W. E., Lynch, C. D., Cooney, P. T., & Hutchins, P. M. (1997) · Endocrinology · doi:10.1210/endo.138.8.5330 · Cited by 307 · see citing works

Brain aromatase is neuroprotective

Azcoitia, Í., Sierra, A., Veiga, S. J., Honda, S., Harada, N., & García‐Segura, L. M. (2001) · Journal of Neurobiology · doi:10.1002/neu.1038 · Cited by 271 · see citing works

Insulin-like growth factor-1 ameliorates age-related behavioral deficits

Markowska, A. L., Mooney, M., & Sonntag, W. E. (1998) · Neuroscience · doi:10.1016/s0306-4522(98)00143-2 · Cited by 270 · see citing works

Recommendations for Physical Activity in Patients with Multiple Sclerosis

Petajan, J. H., & White, A. T. (1999) · Sports Medicine · doi:10.2165/00007256-199927030-00004 · Cited by 241 · see citing works

Neuroprotective signaling and the aging brain: take away my food and let me run11Published on the World Wide Web on 24 August 2000.

Mattson, M. P. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02790-6 · Cited by 238 · see citing works

Insulin-like growth factor 1 regulates developing brain glucose metabolism

Cheng, C. M., Reinhardt, R. R., Lee, W.-H., Joncas, G., Patel, S. C., & Bondy, C. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.170008497 · Cited by 204 · see citing works

Inherent Abnormalities in Energy Metabolism in Alzheimer Disease: Interaction with Cerebrovascular Compromise

Blass, J. P., Sheu, R. K.-F., & Gibson, G. E. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06370.x · Cited by 200 · see citing works

Insulin-Like Growth Factor-I and Binding Protein-3 and Risk of Cancer

Giovannucci, E. L. (1999) · Hormone Research in Paediatrics · doi:10.1159/000053160 · Cited by 195 · see citing works

Insulin-like Growth Factors Regulate Neuronal Differentiation and Survival

Feldman, E. L., Sullivan, K. A., Kim, B., & Russell, J. W. (1997) · Neurobiology of Disease · doi:10.1006/nbdi.1997.0156 · Cited by 187 · see citing works

Responses of the Growth Hormone (GH) and Insulin-Like Growth Factor Axis to Exercise, GH Administration, and GH Withdrawal in Trained Adult Males: A Potential Test for GH Abuse in Sport1

Wallace, J. D., Cuneo, R. C., Baxter, R. C., Ørskov, H., Keay, N., Pentecost, C., Dall, R., Rosén, T., Jørgensen, J. O. L., Cittadini, A., et al. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6037 · Cited by 177 · see citing works

Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia

Fernandez, A. M., de la Vega, A. G., & Torres‐Alemán, I. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1253 · Cited by 164 · see citing works

Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons.

Prehn, J. H. M., Bindokas, V. P., Jordán, J., Galindo, M. F., Ghadge, G. D., Roos, R. P., Boise, L., Thompson, C. B., Krajewski, S., Reed, J. C., et al. (1996) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)08714-0 · Cited by 161 · see citing works

Cellular Mechanisms of Brain Energy Metabolism. Relevance to Functional Brain Imaging and to Neurodegenerative Disordersa

Magistretti, P. J., & Pellerin, L. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb34449.x · Cited by 159 · see citing works

Therapeutic effects of complex motor training on motor performance deficits induced by neonatal binge-like alcohol exposure in rats

Klintsova, A. Y., Cowell, R. M., Swain, R. A., Napper, R. M. A., Goodlett, C. R., & Greenough, W. T. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00495-8 · Cited by 153 · see citing works

Domoic acid: A dementia-inducing excitotoxic food poison with kainic acid receptor specificity

Stewart, G. R., Zorumski, C. F., Price, M. T., et al. (1990) · Experimental Neurology · doi:10.1016/0014-4886(90)90057-y · Cited by 149 · see citing works

Enhancement of spatial learning in F344 rats by physical activity and related learning-associated alterations in hippocampal and cortical cholinergic functioning

Fordyce, D. E., & Farrar, R. P. (1991) · Behavioural Brain Research · doi:10.1016/s0166-4328(05)80105-6 · Cited by 144 · see citing works

Responses of the Growth Hormone (GH) and Insulin-Like Growth Factor Axis to Exercise, GH Administration, and GH Withdrawal in Trained Adult Males: A Potential Test for GH Abuse in Sport

Wallace, J. D. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.10.3591 · Cited by 139 · see citing works

Neurodegeneration Is Associated to Changes in Serum Insulin-like Growth Factors

Busiguina, S., Fernandez, A. M., Barrios, V., Clark, R., Tolbert, D. L., Berciano, J., & Torres‐Alemán, I. (2000) · Neurobiology of Disease · doi:10.1006/nbdi.2000.0311 · Cited by 137 · see citing works

Patterns of Insulin‐like Growth Factor and IGF Receptor Gene Expression in the Brain: Functional Implications

Bondy, C. A., & LEE, W. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb26203.x · Cited by 135 · see citing works

Alterations in GLUT1 and GLUT3 glucose transporter gene expression following unilateral hypoxia–ischemia in the immature rat brain

Vannucci, S. J., Reinhart, R. A., Maher, F., et al. (1998) · Developmental Brain Research · doi:10.1016/s0165-3806(98)00021-2 · Cited by 112 · see citing works

Serum Growth Factors and Neuroprotective Surveillance

Torres‐Alemán, I. (2000) · Molecular Neurobiology · doi:10.1385/mn:21:3:153 · Cited by 104 · see citing works

Superior Water Maze Performance and Increase in Fear-Related Behavior in the Endothelial Nitric Oxide Synthase-Deficient Mouse Together with Monoamine Changes in Cerebellum and Ventral Striatum

Frisch, C., Dere, E., Silva, M. A. D. S., Gödecke, A., Schrader, J., & Huston, J. P. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-17-06694.2000 · Cited by 96 · see citing works

Neuroprotective actions of peripherally administered insulin‐like growth factor I in the injured olivo‐cerebellar pathway

Fernandez, A. M., de la Vega, A. G., Planas, B., & Torres‐Alemán, I. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00623.x · Cited by 86 · see citing works

Excitotoxicity and neurodegenerative diseases

Ikonomidou, C., & Turski, L. (1995) · Current Opinion in Neurology · doi:10.1097/00019052-199512000-00017 · Cited by 82 · see citing works

Elder Rehab: A Student-Supervised Exercise Program for Alzheimer's Patients

Arkin, S. M., & Morrow-Howell, N. L. (1999) · The Gerontologist · doi:10.1093/geront/39.6.729 · Cited by 77 · see citing works

Aging as a major risk for degenerative diseases of the central nervous system

Amaducci, L. A., & Tesco, G. (1994) · Current Opinion in Neurology · doi:10.1097/00019052-199408000-00001 · Cited by 71 · see citing works

Insulin-like growth factor-I and new opportunities for cancer prevention

Holly, J. M. P. (1998) · The Lancet · doi:10.1016/s0140-6736(05)79438-1 · Cited by 67 · see citing works

Reduced immunoreactivity to calcium-binding proteins in Purkinje cells precedes onset of ataxia in spinocerebellar ataxia-1 transgenic mice

Vig, P. J., Subramony, S., Burright, E., Fratkin, J., McDaniel, D., Desaiah, D., & Qin, Z. (1998) · Neurology · doi:10.1212/wnl.50.1.106 · Cited by 67 · see citing works

Cerebral blood flow and metabolism during exercise.

Ide, K., & Secher, N. (2000) · Progress in neurobiology · doi:10.1016/s0301-0082(99)00057-x · Cited by 60 · see citing works

Calbindin-D 28k immunoreactivity in the cerebellum of spinocerebellar degeneration

Ishikawa, K., Mizusawa, H., Fujita, T., et al. (1995) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(94)00279-w · Cited by 50 · see citing works

Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood–brain barrier breakdown induced by impaired oxidative metabolism

Calingasan, N. Y., & Gibson, G. E. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02933-4 · Cited by 49 · see citing works

Insulin-like growth factor I stimulate angiogenesis and the production of vascular endothelial growth factor

Dunn, S. E. (2000) · Growth Hormone & IGF Research · doi:10.1016/s1096-6374(00)90020-0 · Cited by 47 · see citing works

Parenteral domoic acid impairs spatial learning in mice

Petrie, B. F., Pinsky, C., Standish, N. M., et al. (1992) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(92)90084-s · Cited by 44 · see citing works

Insulin‐like growth factor I is an afferent trophic signal that modulates calbindin‐28kD in adult Purkinje cells

Nieto‐Bona, M. P., Busiguina, S., & Torres‐Alemán, I. (1995) · Journal of Neuroscience Research · doi:10.1002/jnr.490420311 · Cited by 34 · see citing works

Risk Factors for Cerebral Degenerative Changes and Dementia

Meyer, J. S., Terayama, Y., Konno, S., et al. (1998) · European Neurology · doi:10.1159/000052064 · Cited by 30 · see citing works

Limitations in the neuroprotective potential of gene therapy with Bcl-2

Phillips, R. G., Lawrence, M. S., Ho, D. Y., et al. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02453-1 · Cited by 30 · see citing works

Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse

Van Pett, K., Viau, V., Bittencourt, J. C., Chan, R. K. W., Li, H.-Y., Arias, C., Prins, G. S., Perrin, M., Vale, W., & Sawchenko, P. E. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20001211)428:2

Exercise: a behavioral intervention to enhance brain health and plasticity

Cotman, C. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02143-4 · Cited by 2,739 · see citing works

Lack of Exercise Is a Major Cause of Chronic Diseases

Booth, F. W., Roberts, C. K., & Laye, M. J. (2012) · Comprehensive Physiology · doi:10.1002/cphy.c110025 · Cited by 2,575 · see citing works

Exercise builds brain health: key roles of growth factor cascades and inflammation

Cotman, C. W., Berchtold, N. C., & Christie, L.-A. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.06.011 · Cited by 2,268 · see citing works

Aerobic Exercise Training Increases Brain Volume in Aging Humans

Colcombe, S. J., Erickson, K. I., Scalf, P. E., Kim, J. S., Prakash, R., McAuley, E., Elavsky, S., Marquez, D. X., Hu, L., & Kramer, A. F. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.11.1166 · Cited by 2,134 · see citing works

Brain foods: The effects of nutrients on brain function.

Gómez-Pinilla, F. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2421 · Cited by 1,372 · see citing works

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Ziv, Y., Ron, N., Butovsky, O., Landa, G., Sudai, E., Greenberg, N., Cohen, H., Kipnis, J., & Schwartz, M. (2006) · Nature Neuroscience · doi:10.1038/nn1629 · Cited by 1,209 · see citing works

Effects of Aerobic Exercise on Mild Cognitive Impairment: A Controlled Trial

Baker, L. D., Frank, L. L., Foster-Schubert, K., Green, P. S., Wilkinson, C. W., McTiernan, A., Plymate, S. R., Fishel, M. A., Watson, G. S., Cholerton, B. A., et al. (2010) · Archives of Neurology · doi:10.1001/archneurol.2009.307 · Cited by 1,171 · see citing works

Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration

Thorne, R. G., Pronk, G. J., Padmanabhan, V., & Frey, W. H. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.05.029 · Cited by 958 · see citing works

Physical Activity, Diet, and Risk of Alzheimer Disease

Scarmeas, N. (2009) · JAMA · doi:10.1001/jama.2009.1144 · Cited by 916 · see citing works

Exercise, cognition, and the aging brain

Kramer, A. F., Erickson, K. I., & Colcombe, S. J. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00500.2006 · Cited by 719 · see citing works

Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms

Booth, F. W., Roberts, C. K., Thyfault, J. P., Ruegsegger, G. N., & Toedebusch, R. G. (2017) · Physiological Reviews · doi:10.1152/physrev.00019.2016 · Cited by 696 · see citing works

Health Benefits of Exercise

Ruegsegger, G. N., & Booth, F. W. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a029694 · Cited by 690 · see citing works

Intermittent metabolic switching, neuroplasticity and brain health

Mattson, M. P., Moehl, K., Ghena, N., Schmaedick, M., & Cheng, A. (2018) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.156 · Cited by 624 · see citing works

Exercise, brain, and cognition across the life span.

Voss, M. W., Nagamatsu, L. S., Liu-Ambrose, T., & Kramer, A. F. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00210.2011 · Cited by 601 · see citing works

Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus

Berchtold, N. C., Chinn, G., Chou, M., Kesslak, J. P., & Cotman, C. W. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.03.026 · Cited by 471 · see citing works

License to run: Exercise impacts functional plasticity in the intact and injured central nervous system by using neurotrophins

Vaynman, S., & Gomez-Pinilla, F. (2005) · Neurorehabilitation and Neural Repair · doi:10.1177/1545968305280753 · Cited by 420 · see citing works

Environment and Brain Plasticity: Towards an Endogenous Pharmacotherapy

Sale, A., Berardi, N., & Maffei, L. (2014) · Physiological Reviews · doi:10.1152/physrev.00036.2012 · Cited by 402 · see citing works

Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease

Tillerson, J. L., Caudle, W. M., Reverón, M. E., & Miller, G. W. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00096-4 · Cited by 399 · see citing works

Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain

Åberg, N. D., Brywe, K. G., & Isgaard, J. (2006) · The Scientific World JOURNAL · doi:10.1100/tsw.2006.22 · Cited by 387 · see citing works

Insulin-like growth factor I is required for vessel remodeling in the adult brain.

Lopez-Lopez, C., LeRoith, D., & Torres-Aleman, I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400337101 · Cited by 385 · see citing works

Cardiorespiratory fitness and brain atrophy in early Alzheimer disease.

Burns, J. M., Cronk, B. B., Anderson, H. S., Donnelly, J. E., Thomas, G. P., Harsha, A., Brooks, W. M., & Swerdlow, R. H. (2008) · Neurology · doi:10.1212/01.wnl.0000317094.86209.cb · Cited by 363 · see citing works

Physical exercise, neuroplasticity, spatial learning and memory

Cassilhas, R. C., Tufik, S., & de Mello, M. T. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2102-0 · Cited by 340 · see citing works

Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches

Thoenen, H., & Sendtner, M. (2002) · Nature Neuroscience · doi:10.1038/nn938 · Cited by 336 · see citing works

Insulin-like growth factor-I and neurogenesis in the adult mammalian brain

Anderson, M. F., Åberg, M. A. I., Nilsson, M., & Eriksson, P. S. (2002) · Developmental Brain Research · doi:10.1016/s0165-3806(02)00277-8 · Cited by 314 · see citing works

Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders

Laviola, G., Hannan, A. J., Macrì, S., Solinas, M., & Jaber, M. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.05.001 · Cited by 300 · see citing works

Revenge of the “Sit”: How lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity

Vaynman, S., & Gomez‐Pinilla, F. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20979 · Cited by 299 · see citing works

Cognitive and Physical Activity Differently Modulate Disease Progression in the Amyloid Precursor Protein (APP)-23 Model of Alzheimer’s Disease

Wolf, S. A., Kronenberg, G., Lehmann, K., Blankenship, A., Overall, R., Staufenbiel, M., & Kempermann, G. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.004 · Cited by 288 · see citing works

The exercise-induced expression of BDNF within the hippocampus varies across life-span

Adlard, P. A., Perreau, V. M., & Cotman, C. W. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.05.006 · Cited by 260 · see citing works

Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF

Cohen, A. D., Tillerson, J. L., Smith, A. D., Schallert, T., & Zigmond, M. J. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01657.x · Cited by 243 · see citing works

Regulation of IGF-I function by proinflammatory cytokines: At the interface of immunology and endocrinology

O’Connor, J. C., McCusker, R. H., Strle, K., Johnson, R. W., Dantzer, R., & Kelley, K. W. (2008) · Cellular Immunology · doi:10.1016/j.cellimm.2007.09.010 · Cited by 238 · see citing works

Potential Mechanisms Underlying Centralized Pain and Emerging Therapeutic Interventions

Eller-Smith, O. C., Nicol, A. L., & Christianson, J. A. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00035 · Cited by 227 · see citing works

Protein hormones and immunity

Kelley, K. W., Weigent, D. A., & Kooijman, R. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2006.11.010 · Cited by 217 · see citing works

Role of physical exercise on cognitive function in healthy older adults: A systematic review of randomized clinical trials

Sáez de Asteasu, M. L., Martínez-Velilla, N., Zambom-Ferraresi, F., Casas-Herrero, Á., & Izquierdo, M. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2017.05.007 · Cited by 215 · see citing works

Neurocognitive aging and cardiovascular fitness: recent findings and future directions

Colcombe, S. J., Kramer, A. F., McAuley, E., Erickson, K. I., & Scalf, P. (2004) · Journal of Molecular Neuroscience · doi:10.1385/jmn:24:1:009 · Cited by 214 · see citing works

Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression

Duman, R. S. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.3/rsduman · Cited by 210 · see citing works

Neurogenesis decreases during brain maturation from adolescence to adulthood

He, J., & Crews, F. T. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.11.003 · Cited by 187 · see citing works

Exercise intensity influences the temporal profile of growth factors involved in neuronal plasticity following focal ischemia.

Ploughman, M., Granter-Button, S., Chernenko, G., Attwood, Z., Tucker, B. A., Mearow, K. M., & Corbett, D. (2007) · Brain Research · doi:10.1016/j.brainres.2007.02.065 · Cited by 170 · see citing works

The effects of physical exercise and cognitive training on memory and neurotrophic factors.

Heisz, J. J., Clark, I. B., Bonin, K., Paolucci, E. M., Michalski, B., Becker, S., & Fahnestock, M. (2017) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01164 · Cited by 144 · see citing works

Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour.

LLorens-Martín, M., Torres-Alemán, I., & Trejo, J. L. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.02.006 · Cited by 135 · see citing works

Redefining neuroendocrinology: Epigenetics of brain-body communication over the life course

McEwen, B. S. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2017.11.001 · Cited by 129 · see citing works

Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent

Chen, M. J., & Russo‐Neustadt, A. A. (2009) · Hippocampus · doi:10.1002/hipo.20579 · Cited by 129 · see citing works

Extended voluntary running inhibits exercise-induced adult hippocampal progenitor proliferation in the spontaneously hypertensive rat.

Naylor, A. S., Persson, A. I., Eriksson, P. S., Jonsdottir, I. H., & Thorlin, T. (2005) · Journal of Neurophysiology · doi:10.1152/jn.01085.2004 · Cited by 127 · see citing works

Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise

Duman, C. H., Schlesinger, L., Terwilliger, R., Russell, D. S., Newton, S. S., & Duman, R. S. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.11.016 · Cited by 123 · see citing works

Insulin-Like Growth Factor 1 (IGF-1) Mediates the Effects of Enriched Environment (EE) on Visual Cortical Development

Ciucci, F., Putignano, E., Baroncelli, L., Landi, S., Berardi, N., & Maffei, L. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000475 · Cited by 119 · see citing works

Exercising our brains: how physical activity impacts synaptic plasticity in the dentate gyrus.

Christie, B. R., Eadie, B. D., Kannangara, T. S., Robillard, J. M., Shin, J., & Titterness, A. K. (2008) · NeuroMolecular Medicine · doi:10.1007/s12017-008-8033-2 · Cited by 99 · see citing works

Neurotrophic factors in Parkinson’s disease are regulated by exercise: Evidence-based practice

da Silva, P. G. C., Domingues, D. D., de Carvalho, L. A., Allodi, S., & Correa, C. L. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.02.017 · Cited by 87 · see citing works

Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord

Engesser-Cesar, C., Anderson, A. J., & Cotman, C. W. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.10.016 · Cited by 80 · see citing works

Age-specific effects of voluntary exercise on memory and the older brain

Siette, J., Westbrook, R. F., Cotman, C., Sidhu, K., Zhu, W., Sachdev, P., & Valenzuela, M. J. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.05.034 · Cited by 78 · see citing works

Brainstem and Midbrain Lesions

(2009) · Springer eBooks · doi:10.1007/978-4-431-26920-5_5

Activation of the brainstem precedes and outlasts the K-complex in humans

Kohsaka, S., Sakai, T., Kohsaka, M., et al. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.11.063 · Cited by 6 · see citing works

Evaluation of brainstem stroke using brainstem auditory evoked responses.

JStern, B., AKrumholz, DWeiss, H., et al. (1982) · Stroke

Brainstem mechanisms of behavior

Klemm, W. R., & Vertes, R. P. (1990) · Medical Entomology and Zoology · Cited by 122 · see citing works

Brainstem death: implications in India.

Sethi, N. K., & Sethi, P. K. (2003) · PubMed · Cited by 12 · see citing works