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Liu, Y., Fu, Y., Xue, X., Tang, G., & Si, L. (2023) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2023.12241 · Cited by 2 · see citing works

Targeted Protein Degraders- The Druggability Perspective

Singh, S., & Srivastava, P. (2023) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2023.10.023 · Cited by 1 · see citing works

PROTAC-mediated multi-target protein degradation in Alzheimer's disease: mechanistic insights, therapeutic applications, and translational challenges

Wang, B., Li, Y., Yao, T., Shen, X., Li, H., Jiang, W., Li, X., & Zhu, Z. (2026) · RSC Medicinal Chemistry · doi:10.1039/d5md00963d · Cited by 1 · see citing works

Attacking the “undruggable” target: The rise and evolution of targeted protein degradation technologies

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A BRD’s (BiRD’s) eye view of BET and BRPF bromodomains in neurological diseases

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Faculty Opinions recommendation of Major Advances in Targeted Protein Degradation: PROTACs, LYTACs, and MADTACs.

Lowe, J. A., III (2021) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.739908982.793584562

Discussion

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Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

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Remodeling at the intersection of time and tissue: Aging, obesity, and the MT1-MMP proteolytic driver in ovarian cancer

Strasiotto, B. C., & Stack, M. S. (2026) · The Enzymes · doi:10.1016/bs.enz.2026.07.002

Bromodomain‐Containing Protein 4 in Ischemia‐Reperfusion Injury: Mechanisms, Preclinical Evidence, and Translational Challenges

Vadak, N., & Bhatt, L. K. (2026) · Cell Biology International · doi:10.1002/cbin.70223

BindingDB Entry 50021924: Recent insights of PROTAC developments in inflammation-mediated and autoimmune targets: a critical review.

BindingDB (2025) · UC San Diego · doi:10.7270/q2pz5fhg

BindingDB Entry 50019285: Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines.

BindingDB (2024) · UC San Diego · doi:10.7270/q2pc36qn

BindingDB Entry 50016515: Nucleic-Acid-Based Targeted Degradation in Drug Discovery.

BindingDB (2023) · UC San Diego · doi:10.7270/q2k35zpc

BindingDB Entry 50007847: Development of selective small molecule MDM2 degraders based on nutlin.

BindingDB (2021) · UC San Diego · doi:10.7270/q22j6g6h

Chemical genetic screens combine target dependence with efficacy: discovery of a MAP3K1 degrader (HBC-8) with anticancer activities

Umeta, L. T., Mallareddy, J. R., Singh, S., Vishwakarma, K., Kizhake, S., Wu, W., Kizhake, A. G., Boghean, L., Vishwakarma, S., Kachhia, M., et al. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00632-z

Selective degradation of BET proteins with dBET1 attenuates lipopolysaccharide‐induced pro‐inflammatory response in microglia

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The Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins Protects Against Microglia-Mediated Neuronal Loss In Vitro

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BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses

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RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells

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Betulinic Acid Inhibits LPS-Induced MMP-9 Expression by Suppressing NF-kB Activation in BV2 Microglial Cells

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