Insulin-like growth factor I, growth hormone and insulin in white adipose tissue

Signal transduction by receptors with tyrosine kinase activity

Ullrich, A., & Schlessinger, J. (1990) · Cell · doi:10.1016/0092-8674(90)90801-k · Cited by 5,435 · see citing works

Insulin signalling and the regulation of glucose and lipid metabolism

Saltiel, A. R., & Kahn, C. R. (2001) · Nature · doi:10.1038/414799a · Cited by 5,326 · see citing works

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Liu, J.-P., Baker, J. C., Perkins, A. S., Robertson, E. J., & Efstratiadis, A. (1993) · Cell · doi:10.1016/s0092-8674(05)80084-4 · Cited by 2,854 · see citing works

Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution.

Krotkiewski, M., Björntorp, P. A., Sjöström, L., & Smith, U. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111040 · Cited by 1,448 · see citing works

Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue

Blüher, M., Kahn, B. B., & Kahn, C. R. (2003) · Science · doi:10.1126/science.1078223 · Cited by 1,348 · see citing works

Molecular and Cellular Endocrinology

Rainey, W. E., & Rodgers, R. J. (2004) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2004.10.007 · Cited by 1,309 · see citing works

Minireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis

Rajala, M. W., & Scherer, P. E. (2003) · Endocrinology · doi:10.1210/en.2003-0580 · Cited by 1,190 · see citing works

Actions of Insulin-Like Growth Factors

Froesch, E. R., Schmid, C., Schwander, J., & Zapf, J. (1985) · Annual Review of Physiology · doi:10.1146/annurev.ph.47.030185.002303 · Cited by 1,154 · see citing works

TRANSCRIPTIONAL REGULATION OF GENE EXPRESSION DURING ADIPOCYTE DIFFERENTIATION

MacDougald, O. A., & Lane, M. D. (1995) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.64.070195.002021 · Cited by 1,064 · see citing works

Insulin-like growth factors and their binding proteins

Sara, V. R., & Hall, K. E. (1990) · Physiological Reviews · doi:10.1152/physrev.1990.70.3.591 · Cited by 929 · see citing works

Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

Gavrilova, O., Marcus-Samuels, B., Graham, D., Kim, J. K., Shulman, G. I., Castle, A. L., Vinson, C., Eckhaus, M., & Reitman, M. L. (2000) · Journal of Clinical Investigation · doi:10.1172/jci7901 · Cited by 676 · see citing works

Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.

Smith, P. J., Wise, L. S., Berkowitz, R., Wan, C. F., & Rubin, C. S. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76555-7 · Cited by 511 · see citing works

Dose-response curves for in vivo insulin sensitivity in individual tissues in rats

Kraegen, E. W., James, D. E., Jenkins, A. B., & Chisholm, D. J. (1985) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1985.248.3.e353 · Cited by 409 · see citing works

Regulation of Adipose Cell Number in Man

Prins, J. B., & O'rahilly, S. (1997) · Clinical Science · doi:10.1042/cs0920003 · Cited by 406 · see citing works

Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhoea and anorexia nervosa.

Chan, J. L., & Mantzoros, C. S. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66830-4 · Cited by 382 · see citing works

Growth hormone and the adipose conversion of 3T3 cells

Morikawa, M., Nixon, B. T., & Green, H. (1982) · Cell · doi:10.1016/0092-8674(82)90440-8 · Cited by 255 · see citing works

A Proteomic Approach for Identification of Secreted Proteins during the Differentiation of 3T3-L1 Preadipocytes to Adipocytes

Kratchmarova, I., Kalume, D. E., Blagoev, B., Scherer, P. E., Podtelejnikov, A. V., Molina, H., Bickel, P. E., Andersen, J., Fernandez, M. M., Bunkenborg, J., et al. (2002) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m200006-mcp200 · Cited by 249 · see citing works

Long-Lived Growth Hormone Receptor Knockout Mice: Interaction of Reduced Insulin-Like Growth Factor I/Insulin Signaling and Caloric Restriction

Al-Regaiey, K., Masternak, M. M., Bonkowski, M. S., Sun, L. Y., & Bartke, A. (2004) · Endocrinology · doi:10.1210/en.2004-1120 · Cited by 235 · see citing works

The Generation of Insulin-Like Growth Factor-1—Sensitive Cells by Growth Hormone Action

Zezulak, K. M., & Green, H. (1986) · Science · doi:10.1126/science.3726546 · Cited by 196 · see citing works

You are what you secrete

Saltiel, A. R. (2001) · Nature Medicine · doi:10.1038/90911 · Cited by 166 · see citing works

The role of growth hormone/insulin-like growth factors in adipocyte differentiation

Wabitsch, M., Hauner, H., Heinze, E., & Teller, W. M. (1995) · Metabolism · doi:10.1016/0026-0495(95)90220-1 · Cited by 162 · see citing works

Differential Roles of the Insulin and Insulin-like Growth Factor-I (IGF-I) Receptors in Response to Insulin and IGF-I

Entingh, A. J., & Kahn, C. R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313201200 · Cited by 142 · see citing works

Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth.

Valet, P., Pagès, C., Jeanneton, O., Daviaud, D., Barbe, P., Record, M., Saulnier‐Blache, J. S., & Lafontan, M. (1998) · Journal of Clinical Investigation · doi:10.1172/jci806 · Cited by 136 · see citing works

Are the metabolic effects of GH and IGF-I separable?

Mauras, N., & Haymond, M. W. (2005) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2004.12.003 · Cited by 131 · see citing works

The Glucose Uptake of Human Adipose Tissue in Obesity

Bjöentorp, P., Berchtold, P., Holm, J., & Larsson, B. (1971) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.1971.tb00559.x · Cited by 120 · see citing works

Contribution of Growth Hormone to the Adipogenic Activity of Serum*

Nixon, B. T., & Green, H. (1984) · Endocrinology · doi:10.1210/endo-114-2-527 · Cited by 113 · see citing works

Role of Insulin Action and Cell Size on Protein Expression Patterns in Adipocytes

Blüher, M., Wilson-Fritch, L., Leszyk, J., Laustsen, P. G., Corvera, S., & Kahn, C. R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m404570200 · Cited by 104 · see citing works

Experimental IGF-I Receptor Deficiency Generates a Sexually Dimorphic Pattern of Organ-Specific Growth Deficits in Mice, Affecting Fat Tissue in Particular

Holzenberger, M., Hamard, G., Zaoui, R., Leneuve, P., Ducos, B., Beccavin, C., Périn, L., & Bouc, Y. L. (2001) · Endocrinology · doi:10.1210/endo.142.10.8461 · Cited by 100 · see citing works

Effects of Growth Hormone Overexpression and Growth Hormone Resistance on Neuroendocrine and Reproductive Functions in Transgenic and Knock‐Out Mice2

Bartke, A., Chandrashekar, V., Turyn, D., Steger, R. W., Debéljuk, L., Winters, T. A., Mattison, J. A., Danilovich, N., Croson, W., Wernsing, D. R., et al. (1999) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.1999.d01-121.x · Cited by 88 · see citing works

IGF-I- and IGFBP-3-Expression in Cultured Human Preadipocytes and Adipocytes

Wabitsch, M., Heinze, E., Debatin, K., & Blum, W. F. P. (2000) · Hormone and Metabolic Research · doi:10.1055/s-2007-978685 · Cited by 83 · see citing works

Regulation of development and metabolism of adipose tissue by growth hormone and the insulin-like growth factor system

Louveau, I., & Gondret, F. (2004) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2004.06.004 · Cited by 80 · see citing works

Insulinlike Growth Factor Action and Production in Adipocytes and Endothelial Cells From Human Adipose Tissue

Kern, P. A., SVOBODA, M. E., Eckel, R. H., & Wyk, J. J. V. (1989) · Diabetes · doi:10.2337/diab.38.6.710 · Cited by 75 · see citing works

Characterization of differentiated subcutaneous and visceral adipose tissue from children

Grohmann, M. J., Sabin, M. A., Holly, J. M. P., Hamilton-Shield, J. P., Crowne, E. C., & Stewart, C. E. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m400295-jlr200 · Cited by 68 · see citing works

Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by growth hormone in rat white adipose tissue.

Peter, M., Winterhalter, K. H., Böni‐Schnetzler, M., et al. (1993) · Endocrinology · doi:10.1210/endo.133.6.7694843 · Cited by 64 · see citing works

Pancreatic Islet-Specific Expression of an Insulin-Like Growth Factor-I Transgene Compensates Islet Cell Growth in Growth Hormone Receptor Gene-Deficient Mice

Guo, Y., Lu, Y., Houle, D., Robertson, K., Tang, Z., Kopchick, J. J., Liu, Y. L., & Liu, J. (2005) · Endocrinology · doi:10.1210/en.2004-1203 · Cited by 60 · see citing works

Insulin-Like Growth Factor 1 Induction of Differentiation of Porcine Preadipocytes4

Ramsay, T. G., White, M. E., & Wolverton, C. K. (1989) · Journal of Animal Science · doi:10.2527/jas1989.6792452x · Cited by 56 · see citing works

Regulation of Insulin-Like Growth Factor-I Ribonucleic Acid Expression, Polypeptide Secretion, and Binding Protein Activity by Growth Hormone in Porcine Preadipocyte Cultures*

Gaskins, H. R., Kim, J.-W., Wright, J. T., et al. (1990) · Endocrinology · doi:10.1210/endo-126-1-622 · Cited by 52 · see citing works

Growth hormone regulation of insulin-like growth factor-I mRNA in rat adipose tissue and isolated rat adipocytes

Vikman, K., Isgaard, J., & Edén, S. (1991) · Journal of Endocrinology · doi:10.1677/joe.0.1310139 · Cited by 48 · see citing works

Differentiation of adipocyte precursors in a serum-free medium is influenced by glucocorticoids and endogenously produced insulin-like growth factor-I.

Nougues, J., Reyne, Y., Barenton, B., et al. (1993) · PubMed · Cited by 47 · see citing works

Phosphatidylinositol-3,4,5-Trisphosphate Is Required for Insulin-Like Growth Factor 1-Mediated Survival of 3T3-L1 Preadipocytes**This work was supported by a grant (to A.S.) from the Medical Research Council of Canada.

Gagnon, A., Dods, P., Roustan-Delatour, N., et al. (2001) · Endocrinology · doi:10.1210/endo.142.1.7902 · Cited by 44 · see citing works

Lipogenic and mitogenic effects of insulin during conversion of Ob17 cells to adipose-like cells

Grimaldi, P., Djian, P., Forest, C. D., et al. (1983) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(83)90017-5 · Cited by 43 · see citing works

Effects of growth hormone on adipose tissue.

Carrel, A. L., & Allen, D. B. (2000) · PubMed · Cited by 35 · see citing works

Insulin and Insulin-like Growth Factor-I Receptor Mediated Differentiation of 3T3-F442A Cells into Adipocytes: Effect of PI 3-Kinase Inhibition

Christoffersen, C. T., Tornqvist, H. E., Vlahos, C. J., Bucchini, D., Jami, J., MEYTS, P. D., & Joshi, R. L. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8637 · Cited by 35 · see citing works

Hormonal regulation of adipose differentiation

Ailhaud, G. P., Grimaldi, P. A., & Négrel, R. (1994) · Trends in Endocrinology and Metabolism · doi:10.1016/1043-2760(94)90095-7 · Cited by 32 · see citing works

Gene expression of the GH receptor in subcutaneous and intraabdominal fat in healthy females: relationship to GH-binding protein

Fisker, S., Hansen, B., Fuglsang, J., et al. (2004) · European Journal of Endocrinology · doi:10.1530/eje.0.1500773 · Cited by 32 · see citing works

Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by growth hormone in rat white adipose tissue

Peter, M. (1993) · Endocrinology · doi:10.1210/en.133.6.2624 · Cited by 29 · see citing works

Insulinlike growth factor action and production in adipocytes and endothelial cells from human adipose tissue

Kern, P., Svoboda, M. E., Eckel, R. H., et al. (1989) · Diabetes · doi:10.2337/diabetes.38.6.710 · Cited by 29 · see citing works

The 20-kD Human Growth Hormone Reduces Body Fat by Increasing Lipolysis and Decreasing Lipoprotein Lipase Activity

Takahashi, S., & Satozawa, N. (2002) · Hormone Research in Paediatrics · doi:10.1159/000065488 · Cited by 28 · see citing works

C-Terminal Src Kinase (CSK) Modulates Insulin-Like Growth Factor-I Signaling through Src in 3T3-L1 Differentiation

Sekimoto, H., & Boney, C. M. (2003) · Endocrinology · doi:10.1210/en.2003-0187 · Cited by 26 · see citing works

Insulin Acutely Regulates Munc18-c Subcellular Trafficking

Nelson, B., Robinson, K. A., & Buse, M. G. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.c100645200 · Cited by 23 · see citing works

Induction of adipose fatty acid binding protein (a-FABP) by insulin-like growth factor-1 (IGF-1) in 3T3-L1 preadipocytes

Blake, W. L., & Clarke, S. D. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(05)81025-3 · Cited by 21 · see citing works

Thyroidal inhibition of chicken pituitary growth hormone: alterations in secretion and accumulation of newly synthesized hormone

Denver, R. J., & Harvey, S. A. K. (1991) · Journal of Endocrinology · doi:10.1677/joe.0.1310039 · Cited by 11 · see citing works

Phosphatidylinositol-3,4,5-Trisphosphate Is Required for Insulin-Like Growth Factor 1-Mediated Survival of 3T3-L1 Preadipocytes

Gagnon, A. (2001) · Endocrinology · doi:10.1210/en.142.1.205 · Cited by 11 · see citing works

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

Boucher, J., Softic, S., El Ouaamari, A., Krumpoch, M. T., Kleinridders, A., Kulkarni, R. N., O’Neill, B. T., & Kahn, C. R. (2016) · Diabetes · doi:10.2337/db16-0212 · Cited by 154 · see citing works

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling

Boucher, J., Mori, M. A., Lee, K. Y., Smyth, G., Liew, C. W., Macotela, Y., Rourk, M., Bluher, M., Russell, S. J., & Kahn, C. R. (2012) · Nature Communications · doi:10.1038/ncomms1905 · Cited by 142 · see citing works

Adipocytes and adipose tissue.

Kiess, W., Petzold, S., Töpfer, M., Garten, A., Blüher, S., Kapellen, T., Körner, A., & Kratzsch, J. (2008) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2007.10.002 · Cited by 130 · see citing works

Interaction of the endocrine system with inflammation: a function of energy and volume regulation

Straub, R. H. (2014) · Arthritis Research & Therapy · doi:10.1186/ar4484 · Cited by 121 · see citing works

MiR-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1

Peiyue, Dong, Yin, Y., et al. (2014) · 生物化学与生物物理学报：英文版

MiR-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1

Dong, P., Mai, Y., Zhang, Z., Mi, L., Wu, G., Chu, G., Yang, G., & Sun, S. (2014) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmu043 · Cited by 45 · see citing works

microRNAs regulate adipocyte differentiation

Chen, L., Song, J., Cui, J., Hou, J., Zheng, X., Li, C., & Liu, L. (2013) · Cell Biology International · doi:10.1002/cbin.10063 · Cited by 69 · see citing works

CBMG, a novel derivative of mansonone G suppresses adipocyte differentiation via suppression of PPARγ activity

Kim, H. K., Hairani, R., Jeong, H., Jeong, M. G., Chavasiri, W., & Hwang, E. S. (2017) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2017.06.017 · Cited by 5 · see citing works

Harnessing adipogenesis to prevent obesity

Haider, N., & Larose, L. (2019) · Adipocyte · doi:10.1080/21623945.2019.1583037 · Cited by 71 · see citing works