Adipogenesis and metabolic health

Positional cloning of the mouse obese gene and its human homologue

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Obesity is associated with macrophage accumulation in adipose tissue

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The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function

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Increased oxidative stress in obesity and its impact on metabolic syndrome

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Mechanisms of fatty acid-induced inhibition of glucose uptake.

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

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Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

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A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

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Differential Significance of Plasma Visfatin Concentrations according to Adiposity in Children and Adolescents

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Fetal and infant growth and impaired glucose tolerance at age 64

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Reactive oxygen species have a causal role in multiple forms of insulin resistance

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What we talk about when we talk about fat

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Dynamics of fat cell turnover in humans

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PRDM16 controls a brown fat/skeletal muscle switch

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Brown and beige fat: Development, function and therapeutic potential

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PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

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PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development

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Inhibition of Adipogenesis by Wnt Signaling

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Transcriptional control of adipocyte formation

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Obesity in Young Men after Famine Exposure in Utero and Early Infancy

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Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution.

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Forming functional fat: a growing understanding of adipocyte differentiation

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Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

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Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

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Obesity-associated improvements in metabolic profile through expansion of adipose tissue

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Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

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Relationship between Adipocyte Size and Adipokine Expression and Secretion

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Tracking adipogenesis during white adipose tissue development, expansion and regeneration

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Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects

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Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

Anderson, E. J., Lustig, M. E., Boyle, K. E., Woodlief, T. L., Kane, D. A., Lin, C.-T., Price, J. W., Kang, L., Rabinovitch, P. S., Szeto, H. H., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci37048 · Cited by 1,253 · see citing works

Leptin-Replacement Therapy for Lipodystrophy

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Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Holland, W. L., Brozinick, J. T., Wang, L.-P., Hawkins, E. D., Sargent, K. M., Liu, Y., Narra, K., Hoehn, K. L., Knotts, T. A., Siesky, A., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.01.002 · Cited by 1,232 · see citing works

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

Cao, H.-M., Gerhold, K., Mayers, J. R., Wiest, M., Watkins, S., & Hotamışlıgil, G. S. (2008) · Cell · doi:10.1016/j.cell.2008.07.048 · Cited by 1,142 · see citing works

Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

Naveiras, O., Nardi, V., Wenzel, P. L., Hauschka, P. V., Fahey, F., & Daley, G. Q. (2009) · Nature · doi:10.1038/nature08099 · Cited by 1,129 · see citing works

White Fat Progenitor Cells Reside in the Adipose Vasculature

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New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

Tseng, Y.-H., Kokkotou, E., Schulz, T. J., Huang, T. L., Winnay, J. N., Taniguchi, C. M., Tran, T. T., Suzuki, R., Espinoza, D. O., Yamamoto, Y., et al. (2008) · Nature · doi:10.1038/nature07221 · Cited by 1,099 · see citing works

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

Khan, T., Muise, E. S., Iyengar, P., Wang, Z. V., Chandalia, M., Abate, N., Zhang, B. B., Bonaldo, P., Chua, S., & Scherer, P. E. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01300-08 · Cited by 1,053 · see citing works

Adipokines in health and disease

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Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy

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Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

Stern, J. H., Rutkowski, J. M., & Scherer, P. E. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.04.011 · Cited by 1,031 · see citing works

Cross-Regulation of C/EBPα and PPARγ Controls the Transcriptional Pathway of Adipogenesis and Insulin Sensitivity

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Brown and Beige Fat: Physiological Roles beyond Heat Generation

Kajimura, S., Spiegelman, B. M., & Seale, P. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.09.007 · Cited by 1,004 · see citing works

Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats.

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Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

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Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

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Nuclear Receptor Expression Links the Circadian Clock to Metabolism

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JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

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Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

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Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

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Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

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Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration

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Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

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PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scalePreprint

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Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

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Identification of the gene altered in Berardinelli–Seip congenital lipodystrophy on chromosome 11q13

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Biochemical and cellular properties of insulin receptor signalling

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PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function.

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The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation

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Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials

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Neonatal anthropometry: the thin–fat Indian baby. The Pune Maternal Nutrition Study

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Control of brown and beige fat development

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Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

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In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

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Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling

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Mitochondrial Complex III ROS Regulate Adipocyte Differentiation

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Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology

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Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling

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Increased Infiltration of Macrophages in Omental Adipose Tissue Is Associated With Marked Hepatic Lesions in Morbid Human Obesity

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Induction of Peroxisome Proliferator-Activated Receptor γ during the Conversion of 3T3 Fibroblasts into Adipocytes Is Mediated by C/EBPβ, C/EBPδ, and Glucocorticoids

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Targeting senescent cells enhances adipogenesis and metabolic function in old age

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Rosiglitazone Revisited

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Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

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Regeneration of fat cells from myofibroblasts during wound healing

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The role of adipose cell size and adipose tissue insulin sensitivity in the carbohydrate intolerance of human obesity

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Caveolin-1-deficient Mice Are Lean, Resistant to Diet-induced Obesity, and Show Hypertriglyceridemia with Adipocyte Abnormalities

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A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2

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A Transgenic Mouse with a Deletion in the Collagenous Domain of Adiponectin Displays Elevated Circulating Adiponectin and Improved Insulin Sensitivity

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Characterization of the adipocyte cellular lineage in vivo

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Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones

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Transcriptional control of preadipocyte determination by Zfp423

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Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis

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Function of GATA Transcription Factors in Preadipocyte-Adipocyte Transition

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