The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.
Advanced hydrogels for the repair of cartilage defects and regeneration
Open accessAbstract
Cartilage defects are one of the most common symptoms of osteoarthritis (OA), a degenerative disease that affects millions of people world-wide and places a significant socio-economic burden on society. Hydrogels, which are a class of biomaterials that are elastic, and display smooth surfaces while exhibiting high water content, are promising candidates for cartilage regeneration. In recent years, various kinds of hydrogels have been developed and applied for the repair of cartilage defects in vitro or in vivo, some of which are hopeful to enter clinical trials. In this review, recent research findings and developments of hydrogels for cartilage defects repair are summarized. We discuss the principle of cartilage regeneration, and outline the requirements that have to be fulfilled for the deployment of hydrogels for medical applications. We also highlight the development of advanced hydrogels with tailored properties for different kinds of cartilage defects to meet the requirements of cartilage tissue engineering and precision medicine.
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1 retracted
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Highly stretchable and tough hydrogels
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Cited by
Han, Y., Yang, J., Zhao, W., Wang, H., Sun, Y., Chen, Y., Luo, J., Deng, L., Xu, X., Cui, W., et al. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.03.022 · Cited by 308
Pita-López, M. L., Fletes-Vargas, G., Espinosa-Andrews, H., & Rodríguez-Rodríguez, R. (2021) · European Polymer Journal · doi:10.1016/j.eurpolymj.2020.110176 · Cited by 256
Advanced 3D-Printing Bioinks for Articular Cartilage Repair
Liang, Q., Ma, Y., Yao, X., & Wei, W. (2022) · International Journal of Bioprinting · doi:10.18063/ijb.v8i3.511 · Cited by 55
Self-citationPEG Reinforced Scaffold Promotes Uniform Distribution of Human MSC-Created Cartilage Matrix
Riewruja, K., Aguglia, A. M., Hines, S., Makarcyzk, M. J., Honsawek, S., & Lin, H. (2022) · Gels · doi:10.3390/gels8120794 · Cited by 9
Metadata
- Authors
- Wei, W., Ma, Y., Yao, X., Zhou, W., Wang, X., Li, C., Lin, J., He, Q., Leptihn, S., & Ouyang, H.
- Venue
- Bioactive Materials
- Publisher
- Elsevier BV
- Published
- 2021-04
- Volume
- 6
- Issue
- 4
- Pages
- 998-1011
- ISSN
- 2097-1192 (ISSN-L)
- 2452-199X
- OpenAlex
- W3092452908
- Cited by
- 357
- References
- 149
- FWCI
- 32.58
- Type
- journal article
- Language
- en
- Open access
- gold
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- Wei, W., Ma, Y., Yao, X., Zhou, W., Wang, X., Li, C., Lin, J., He, Q., Leptihn, S., & Ouyang, H. (2021). Advanced hydrogels for the repair of cartilage defects and regeneration. Bioactive Materials. https://doi.org/10.1016/j.bioactmat.2020.09.030
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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