Cited by 705Muscle Physiology and DisordersMuscle metabolism and nutritionNutrition and Health in Aging

The DOI matches its Crossref record; 155 of the 157 references it cites were found in a registry or an index.

Glucocorticoid-induced skeletal muscle atrophy

Schakman, O., Kalista, S., Barbé, C., Loumaye, A., Thissen, J.P.·2013·The International Journal of Biochemistry & Cell Biology

DOI 10.1016/j.biocel.2013.05.036

Open this paper in CoChat — free account

Abstract

Many pathological states characterized by muscle atrophy (e.g., sepsis, cachexia, starvation, metabolic acidosis and severe insulinopenia) are associated with an increase in circulating glucocorticoids (GC) levels, suggesting that GC could trigger the muscle atrophy observed in these conditions. GC-induced muscle atrophy is characterized by fast-twitch, glycolytic muscles atrophy illustrated by decreased fiber cross-sectional area and reduced myofibrillar protein content. GC-induced muscle atrophy results from increased protein breakdown and decreased protein synthesis. Increased muscle proteolysis, in particular through the activation of the ubiquitin proteasome and the lysosomal systems, is considered to play a major role in the catabolic action of GC. The stimulation by GC of these two proteolytic systems is mediated through the increased expression of several Atrogenes ("genes involved in atrophy"), such as FOXO, Atrogin-1, and MuRF-1. The inhibitory effect of GC on muscle protein synthesis is thought to result mainly from the inhibition of the mTOR/S6 kinase 1 pathway. These changes in muscle protein turnover could be explained by changes in the muscle production of two growth factors, namely Insulin-like Growth Factor (IGF)-I, a muscle anabolic growth factor and Myostatin, a muscle catabolic growth factor. This review will discuss the recent progress made in the understanding of the mechanisms involved in GC-induced muscle atrophy and consider the implications of these advancements in the development of new therapeutic approaches for treating GC-induced myopathy. This article is part of a Directed Issue entitled: Molecular basis of muscle wasting.

Integrity signals

Registry

Crossref · 10.1016/j.biocel.2013.05.036

Cites

155 of 155 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

FOXO1 Regulates the Expression of 4E-BP1 and Inhibits mTOR Signaling in Mammalian Skeletal Muscle
Southgate, R. J., Neill, B., Prelovsek, O., El‐Osta, A., Kamei, Y., Miura, S., Ezaki, O., McLoughlin, T. J., Zhang, W., Unterman, T. G., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702039200 · Cited by 112
Retracted
mTOR Signaling in Growth Control and Disease
Laplante, M., & Sabatini, D. M. (2012) · Cell · doi:10.1016/j.cell.2012.03.017 · Cited by 8,509
Identification of ubiquitin ligases required for skeletal muscle atrophy.
Bodine, S. C., Latres, E., Baumhueter, S., Lai, V. K.-M., Nunez, L., Clarke, B. A., Poueymirou, W. T., Panaro, F. J., Na, E., Dharmarajan, K., et al. (2001) · Science · doi:10.1126/science.1065874 · Cited by 3,521
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy.
Sandri, M., Sandri, C., Gilbert, A., Skurk, C., Calabria, E., Picard, A., Walsh, K., Schiaffino, S., Lecker, S. H., & Goldberg, A. L. (2004) · Cell · doi:10.1016/s0092-8674(04)00400-3 · Cited by 3,012
Double muscling in cattle due to mutations in the myostatin gene
McPherron, A. C., & Lee, S.-J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.23.12457 · Cited by 2,039
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways
Rommel, C., Bodine, S. C., Clarke, B. A., Rossman, R., Nunez, L., Stitt, T. N., Yancopoulos, G. D., & Glass, D. J. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1009 · Cited by 1,583
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0610com · Cited by 1,539 · cited 1×
“…analyses of muscle atrophy due to a variety of wasting diseases are several genes (Atrogin-1, MuRF-1, Cathepsin-L, PDK4, p21, Gadd45, 4E-BP1) controlled by the FOXO transcription factors (Almon et al., 2007; Jagoe et al., 2002; Komamura et al., 2003; Lecker et al., 2004; Waddell et al., 2008).”
Background
Mechanisms of Muscle Wasting — The Role of the Ubiquitin–Proteasome Pathway
Mitch, W. E., & Goldberg, A. L. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612193352507 · Cited by 1,163
Growth Hormone and the Insulin-Like Growth Factor System in Myogenesis*
Florini, J. R., Ewton, D. Z., & Coolican, S. A. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-5-481 · Cited by 1,148
Myostatin, a Negative Regulator of Muscle Growth, Functions by Inhibiting Myoblast Proliferation
Thomas, M., Langley, B., Berry, C., Sharma, M., Kirk, S., Bass, J., & Kambadur, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004356200 · Cited by 1,014

Flagged first, then by citations

Show all 157 references

2 of the 157 references couldn’t be matched to a known paper.

Sorted by citations

Items 301–400 of 704

Functions and Therapeutic Potentials of Long Noncoding RNA in Skeletal Muscle Atrophy and Dystrophy
Zhang, Y., Wang, T., Wang, Z., Shi, X., & Jin, J. (2025) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13747 · Cited by 16
Acute supplementation with an amino acid mixture suppressed the exercise-induced cortisol response in recreationally active healthy volunteers: a randomized, double-blinded, placebo-controlled crossover study
Tsuda, Y., Murakami, R., Yamaguchi, M., & Seki, T. (2020) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-020-00369-2 · Cited by 14
Role of Glucocorticoid Signaling and HDAC4 Activation in Diaphragm and Gastrocnemius Proteolytic Activity in Septic Rats
Moreno‐Rupérez, Á., Priego, T., González-Nicolás, M. Á., López‐Calderón, A., Lázaro, A., & Martı́n, A. I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073641 · Cited by 14
Zebrafish Models for Skeletal Muscle Senescence: Lessons from Cell Cultures and Rodent Models
Ichii, S., Matsuoka, I., Okazaki, F., & Shimada, Y. (2022) · Molecules · doi:10.3390/molecules27238625 · Cited by 15
Increased autophagy signaling but not proteasome activity in human skeletal muscle after prolonged low‐intensity exercise with negative energy balance
Moberg, M., Hendo, G., Jakobsson, M., Mattsson, C. M., Ekblom‐Bak, E., Flockhart, M., Pontén, M., Söderlund, K., & Ekblom, B. T. (2017) · Physiological Reports · doi:10.14814/phy2.13518 · Cited by 14
Omega-3 multiple effects increasing glucocorticoid-induced muscle atrophy: autophagic, AMPK and UPS mechanisms
Fappi, A., Neves, J. D. C., Kawasaki, K. A., Bacelar, L., Sanches, L. N., da Silva, F. P., Larina-Neto, R., Chadi, G., & Zanoteli, E. (2019) · Physiological Reports · doi:10.14814/phy2.13966 · Cited by 13
Electrical stimulation of biofidelic engineered muscle enhances myotube size, force, fatigue resistance, and induces a fast‐to‐slow‐phenotype shift
Pallotta, I., Stec, M. J., Schriver, B. J., Golann, D. R., Considine, K., Su, Q., Barahona, V., Napolitano, J. E., Stanley, S., Garcia, M., et al. (2024) · Physiological Reports · doi:10.14814/phy2.70051 · Cited by 13
Sexual Dimorphism in Transcriptional and Functional Glucocorticoid Effects on Mouse Skeletal Muscle
Li, S., Schönke, M., Buurstede, J. C., Moll, T. J. A., Gentenaar, M., Schilperoort, M., Visser, J. A., Kaikaew, K., van de Vijver, D., Abbassi‐Daloii, T., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.907908 · Cited by 13
Delphi-Based Expert Consensus Statements for the Management of Percutaneous Radiofrequency Neurotomy in the Treatment of Lumbar Facet Joint Syndrome
Occhigrossi, F., Carpenedo, R., Leoni, M. L. G., Varrassi, G., Chinè, E., Cascella, M., Francesco, A., Ezio, A., Lucia, A., Carlo, A., et al. (2023) · Pain and Therapy · doi:10.1007/s40122-023-00512-2 · Cited by 13
Oral corticosteroid use and sarcopenia-related traits in older people with chronic airway disease: a population-based study
Benz, E., Lahousse, L., Arinze, J. T., Wijnant, S. R. A., de Ridder, M. A. J., Rivadeneira, F., Brusselle, G., & Stricker, B. H. C. (2023) · ERJ Open Research · doi:10.1183/23120541.00492-2023 · Cited by 13
Effects of Horse Meat Hydrolysate on Oxidative Stress, Proinflammatory Cytokines, and the Ubiquitin-Proteasomal System of C2C12 Cells
Lee, H.-J., Kim, D., Do, K., Yang, C.-B., Jeon, S.-W., & Jang, A. (2023) · Food Science of Animal Resources · doi:10.5851/kosfa.2023.e65 · Cited by 13
Voluntary exercise improves metabolic profile in high-fat fed glucocorticoid-treated rats
Beaudry, J. L., Dunford, E. C., Leclair, E., Mandel, E. R., Peckett, A. J., Haas, T. L., & Riddell, M. C. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00467.2014 · Cited by 13
Brainstem prolactin-releasing peptide contributes to cancer anorexia-cachexia syndrome in rats
Batista, K. N. I., Schraner, M., & Riediger, T. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108289 · Cited by 12
Glucocorticoid-induced myopathy in people with asthma: a systematic review
Wu, K., Michalski, A., Cortes, D., Rozenberg, D., & Mathur, S. (2021) · Journal of Asthma · doi:10.1080/02770903.2021.1926488 · Cited by 13
Random errors in protein synthesis activate an age-dependent program of muscle atrophy in mice
Moore, J. M., Akbergenov, R., Nigri, M., Isnard, P., Grimm, A., Seebeck, P., Restelli, L. M., Frank, S., Eckert, A., Thiam, K., et al. (2021) · Communications Biology · doi:10.1038/s42003-021-02204-z · Cited by 14
Comparative study on molecular mechanism of diabetic myopathy in two different types of streptozotocin-induced diabetic models
Saliu, T. P., Kumrungsee, T., Miyata, K., Tominaga, H., Yazawa, N., Hashimoto, K., Kamesawa, M., & Yanaka, N. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120183 · Cited by 13
Metabolic Pathways and Ion Channels Involved in Skeletal Muscle Atrophy: A Starting Point for Potential Therapeutic Strategies
Canfora, I., Tarantino, N., & Pierno, S. (2022) · Cells · doi:10.3390/cells11162566 · Cited by 16
Exercise Medicine for Osteoarthritis: Research Strategies to Maximize Effectiveness
Bamman, M. M., Wick, T. M., Carmona‐Moran, C. A., & Bridges, S. L. (2015) · Arthritis Care & Research · doi:10.1002/acr.22680 · Cited by 13
Transcript profiles in longissimus dorsi muscle and subcutaneous adipose tissue: A comparison of pigs with different postweaning growth rates1
Pilcher, C. M., Jones, C. K., Schroyen, M., Severin, A. J., Patience, J. F., Tuggle, C. K., & Koltes, J. E. (2015) · Journal of Animal Science · doi:10.2527/jas.2014-8593 · Cited by 13
Preventive Effects of Collagen-Derived Dipeptide Prolyl-Hydroxyproline against Dexamethasone-Induced Muscle Atrophy in Mouse C2C12 Skeletal Myotubes
Kimira, Y., Osawa, K., Osawa, Y., & Mano, H. (2023) · Biomolecules · doi:10.3390/biom13111617 · Cited by 13
11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients
Schluessel, S., Zhang, W., Nowotny, H. F., Bidlingmaier, M., Hintze, S., Kunz, S. L., Martini, S., Mehaffey, S., Meinke, P., Neuerburg, C., et al. (2023) · Aging Clinical and Experimental Research · doi:10.1007/s40520-023-02574-w · Cited by 12
Whey Peptide Alleviates Muscle Atrophy by Strongly Regulating Myocyte Differentiation in Mice
Lee, J. A., Shin, M.-R., Kim, M. J., Kim, H.-Y., Choi, H., Seo, Y., Choi, H.-J., & Roh, S. (2024) · Medicina · doi:10.3390/medicina60030433 · Cited by 12
Potential of Lycii Radicis Cortex as an Ameliorative Agent for Skeletal Muscle Atrophy
Son, R. H., Kim, M. I., Kim, H. M., Guo, S., Lee, D. H., Lim, G. M., Kim, S.-M., Kim, J., & Kim, C. Y. (2024) · Pharmaceuticals · doi:10.3390/ph17040462 · Cited by 14
Altered dynamics of lipid metabolism in muscle cells from patients with idiopathic inflammatory myopathy is ameliorated by 6 months of training
Nemec, M., Vernerová, L., Laiferová, N. A., Balážová, M., Vokurková, M., Kurdiová, T., Oreská, S., Kubínová, K., Klein, M., Špiritović, M., et al. (2020) · The Journal of Physiology · doi:10.1113/jp280468 · Cited by 12
Satellite Cells Exhibit Decreased Numbers and Impaired Functions on Single Myofibers Isolated from Vitamin B6-Deficient Mice
Komaru, T., Yanaka, N., & Kumrungsee, T. (2021) · Nutrients · doi:10.3390/nu13124531 · Cited by 12
The combined effects of treadmill exercise and steroid administration on anterior cruciate ligament reconstruction-induced joint contracture and muscle atrophy in rats
Kaneguchi, A., Takahashi, A., Shimoe, A., Hayakawa, M., Yamaoka, K., & Ozawa, J. (2023) · Steroids · doi:10.1016/j.steroids.2023.109183 · Cited by 12
Evolution of body composition following successful kidney transplantation is strongly influenced by physical activity: results of the CORPOS study
Moreau, K., Desseix, A., Germain, C., Merville, P., Couzi, L., Thiébaut, R., & Chauveau, P. (2021) · BMC Nephrology · doi:10.1186/s12882-020-02214-9 · Cited by 12
α MSH Blunts Endotoxin-Induced MuRF1 and Atrogin-1 Upregulation in Skeletal Muscle by Modulating NF- κ B and Akt/FoxO1 Pathway
Martı́n, A. I., Gómez-SanMiguel, A. B., Gómez-Moreira, C., Villanúa, M. Á., & López‐Calderón, A. (2014) · Mediators of Inflammation · doi:10.1155/2014/179368 · Cited by 12
The Importance of the Training-Induced Decrease in Basal Cortisol Concentration in the Improvement in Muscular Performance in Humans
Grandys, M., Majerczak, J., KULPA, J., Duda, K., Rychlik, U., & Zoladz, J. A. (2016) · Physiological Research · doi:10.33549/physiolres.933039 · Cited by 12
Nelumbinis Stamen Ameliorates Chronic Restraint Stress-Induced Muscle Dysfunction and Fatigue in Mice by Decreasing Serum Corticosterone Levels and Activating Sestrin2
Wang, Z., Jin, S., Xia, T., Liu, Y., Zhou, Y., Liu, X., Pan, R., Liao, Y., Yan, M., & Chang, Q. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c06318 · Cited by 11
Anti-muscle atrophy effect of fermented Tenebrio molitor larvae extract by modulating the PI3K-Akt-mTOR/FoxO3α pathway in mice treated with dexamethasone
Han, J., Choi, S.-Y., Choi, R., Park, K.-W., Kang, K.-Y., & Lee, M. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117266 · Cited by 11
Different magnitude of resistance to non-depolarizing muscle relaxants in dexamethasone-treated rat diaphragm associated with altered acetylcholine receptor expression
Chen, D., Yan, M., Huang, L., QIU, Y.-W., & Li, S. T. (2014) · Genetics and Molecular Research · doi:10.4238/2014.august.7.4 · Cited by 11
The effects of bolus supplementation of branched-chain amino acids on skeletal muscle mass, strength, and function in patients with rheumatic disorders during glucocorticoid treatment
Yoshikawa, N., Shimizu, N., Uehara, M., Oda, A., Matsumiya, R., Matsubara, E., Kobayashi, H., Hosono, O., Souta-Kuribara, A., Baba, H., et al. (2016) · Modern Rheumatology · doi:10.1080/14397595.2016.1213480 · Cited by 11
Elastic net of polyurethane strands for sustained delivery of triamcinolone around silicone implants of various sizes
Huh, B. K., Kim, B. H., Kim, C. R., Kim, S.-N., Shin, B. H., Ji, H. B., Lee, S. H., Kim, M. J., Heo, C. Y., & Choy, Y. B. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.110565 · Cited by 11
Diabète et corticoïdes : nouveautés et aspects pratiques
Bastin, M., & Andréelli, F. (2020) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2020.05.007 · Cited by 11
Diphlorethohydroxycarmalol Derived from Ishige okamurae Improves Behavioral and Physiological Responses of Muscle Atrophy Induced by Dexamethasone in an In-Vivo Model
Ryu, B., Oh, S., Yang, H.-W., Batsukh, S., Chung, D.-M., Seo, M., Park, S., Byun, K., & Jeon, Y. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14040719 · Cited by 11
Combinatory in vitro effects of the β2-agonists salbutamol and formoterol in skeletal muscle cells
Piribauer, M., Jiang, L., Kostov, T., Parr, M., Steidel, S., Bizjak, D. A., Steinacker, J. M., & Diel, P. (2023) · Toxicology Letters · doi:10.1016/j.toxlet.2023.02.007 · Cited by 10
Biological Mechanisms Involved in Muscle Dysfunction in COPD: An Integrative Damage–Regeneration–Remodeling Framework
Gea, J., Orozco‐Levi, M., Pascual-Guàrdia, S., Casadevall, C., Enríquez-Rodríguez, C. J., Camps-Ubach, R., & Barreiro, E. (2025) · Cells · doi:10.3390/cells14211731 · Cited by 12
Glucocorticoid Regulates the Synthesis of Porcine Muscle Protein through m6A Modified Amino Acid Transporter SLC7A7
Xu, W., Guo, K., Shi, J., Guo, C., Xu, J., Zheng, R., Jiang, S., & Chai, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020661 · Cited by 10
Practical cancer cachexia management in palliative care – a review of current evidence
Duffy, T., & Kochanczyk, M. (2023) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000655 · Cited by 11
The Alleviative Effect of Sodium Butyrate on Dexamethasone‐Induced Skeletal Muscle Atrophy
Zhao, X., Zhu, M., Wang, Z., Gao, M., Long, Y., Zhou, S., & Wang, W. (2025) · Cell Biology International · doi:10.1002/cbin.70003 · Cited by 9
Advancing muscle aging and sarcopenia research through spatial transcriptomics
Min, B.-D., Hwang, C. Y., Kim, D., Kim, S.-Y., Jayasinghe, J. N. C., Tran, M. N., Park, S., & Kwon, K. (2025) · Osteoporosis and Sarcopenia · doi:10.1016/j.afos.2025.05.002 · Cited by 12
L-theanine reduces muscle drip loss by regulating oxidative stress-mediated glycolysis disturbance and cytoskeletal protein degradation
Huang, Y. S., Huang, Z., Jia, G., Zhao, H. Y., & Chen, X. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.107424 · Cited by 10
Impact of HSCT Conditioning and Glucocorticoid Dose on Exercise Adherence and Response
Wiskemann, J., HERZOG, B., Kuehl, R., Schmidt, M. E., Steindorf, K., Schwerdtfeger, R., Dreger, P., & Bohus, M. (2017) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001357 · Cited by 10
Local biosynthesis of corticosterone in rat skeletal muscle
Sato, M., Sugiyama, K., Maeda, N., Fujiki, J., Ieko, T., Kawamura, Y., Iwano, H., Mukai, K., & Yokota, H. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2020.105693 · Cited by 9
Sarcopenia in the setting of nonalcoholic fatty liver
Arrese, M. A., Cabello‐Verrugio, C., Arab, J. P., Francisco Barrera, M., Baudrand, R. F., Guarda, F. J., Gul, I., & Cabrera, D. (2022) · Metabolism and Target Organ Damage · doi:10.20517/mtod.2021.16 · Cited by 10
Radiofrequency Neurotomy Does Not Cause Fatty Degeneration of the Lumbar Paraspinal Musculature in Patients with Chronic Lumbar Pain—A Retrospective 3D-Computer-Assisted MRI Analysis Using iSix Software
Oswald, K. A. C., Ekengele, V., Hoppe, S., Streitberger, K., Harnik, M. A., & Albers, C. E. (2022) · Pain Medicine · doi:10.1093/pm/pnac103 · Cited by 10
Application of nanomedicine and mesenchymal stem cells in burn injuries for the elderly patients
Xiong, W., Zhang, R., Zhou, H., Liu, Y., Liang, M., Li, K., Duan, X., Chen, D. P., Luo, Y., Xu, J., et al. (2022) · Smart Materials in Medicine · doi:10.1016/j.smaim.2022.08.001 · Cited by 11
Diosgenin prevents dexamethasone-induced myotube atrophy in C2C12 cells
Yoshioka, Y., Oishi, S., Onoda, K., Shibata, K., & Miyoshi, N. (2023) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2023.109759 · Cited by 12
Glucocorticoid-induced osteoporosis: an overview
Kuchuk, N. O., Hoes, J. N., Bijlsma, J. W. J., & Jacobs, J. W. G. (2014) · International Journal of Clinical Rheumatology · doi:10.2217/ijr.14.24 · Cited by 10
Muscular response to the first three months of deflazacort treatment in boys with Duchenne muscular dystrophy.
Jensen, L., Petersson, S. J., Illum, N. O., Laugaard-Jacobsen, H. C., Thelle, T., Jørgensen, L. H., & Schrøder, H. D. (2017) · Europe PMC (PubMed Central) · Cited by 10
Ferulic Acid Promotes Growth of Both Fast Glycolytic and Slow Oxidative Skeletal Muscles in Corticosteroid-Induced Rat Myopathy
SAMIR, M. D. A. F. M. S. M. (2019) · The Medical Journal of Cairo University/The Medical Journal of Cairo University · doi:10.21608/mjcu.2019.53950 · Cited by 10
Change in skeletal muscle mass is associated with lipid profiles in female rheumatoid arthritis patients -TOMORROW study-
Matsumoto, Y., Sugioka, Y., Tada, M., Okano, T., Mamoto, K., Inui, K., Habu, D., & Koike, T. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.12.028 · Cited by 11
Circadian Clock in Muscle Disease Etiology and Therapeutic Potential for Duchenne Muscular Dystrophy
Kiperman, T., & Ma, K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25094767 · Cited by 9
Guava leaf extract attenuated muscle proteolysis in dexamethasone induced muscle atrophic mice via ubiquitin proteasome system, mTOR-autophagy, and apoptosis pathway
Lee, H., Eo, Y., Kim, S. Y., & Lim, Y. (2024) · Nutrition Research · doi:10.1016/j.nutres.2024.05.009 · Cited by 9
Mealworm hydrolysate ameliorates dexamethasone-induced muscle atrophy via sirtuin 1-mediated signaling and Akt pathway
Kim, S., Kim, J., Jun, E.-M., Jaiswal, V., Park, E.-J., & Lee, H. (2025) · npj Science of Food · doi:10.1038/s41538-025-00432-9 · Cited by 10
Nanoparticle delivery of AMPK activator 991 prevents its toxicity and improves muscle homeostasis in Duchenne muscular dystrophy
Andreana, I., Ghosh, A., Repellin, M., Kneppers, A. E. M., Larbi, S. B., Tifni, F., Fessard, A., Martin, M. J., Sidi‐Boumedine, J., Kryza, D., et al. (2025) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2025.101564 · Cited by 9
Endocrinological aspects of sarcopenic obesity
Minnetti, M., Poggiogalle, E., Frigerio, F., Piciocchi, C., Pierantozzi, G., Vincenzo, O. D., Pinto, A., Gianfrilli, D., Isidori, A. M., Migliaccio, S., et al. (2026) · Annals of Medicine · doi:10.1080/07853890.2026.2626085 · Cited by 13
Cistanche tubulosa (Schenk) Wight Extract Enhances Hindlimb Performance and Attenuates Myosin Heavy Chain IId/IIx Expression in Cast-Immobilized Mice
Kimbara, Y., Shimada, Y., Kuboyama, T., & Tohda, C. (2019) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2019/9283171 · Cited by 9
Short-time recovery skeletal muscle from dexamethasone-induced atrophy and weakness in old female rats
Alev, K., Aru, M., Vain, A., Pehme, A., Kaasik, P., & Seene, T. (2022) · Clinical Biomechanics · doi:10.1016/j.clinbiomech.2022.105808 · Cited by 9
Trajectories of cardiorespiratory fitness in patients with juvenile dermatomyositis
Blom, K. J., Takken, T., Huijgen, B. C. H., Wienke, J., van Royen‐Kerkhof, A., & van Brussel, M. (2017) · Lara D. Veeken · doi:10.1093/rheumatology/kex366 · Cited by 9
Histopathological changes and oxidative damage in type I and type II muscle fibers in rats undergoing paradoxical sleep deprivation
Mônico‐Neto, M., Lee, K. S., da Luz, M. H. M., Pino, J. M. V., Ribeiro, D. A., Cardoso, C. M., Sueur, L. D. P. L., Tufik, S., & Antunes, H. K. M. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.109939 · Cited by 9
Effect of short-term fasting and glucocorticoids on KLF15 expression and branched-chain amino acids metabolism in Chinese perch
Zhu, X., Hu, J., Zhang, J., Liu, J., Bao, L., Pan, Y., Cheng, J. R., & Chu, W. (2021) · Aquaculture Reports · doi:10.1016/j.aqrep.2021.100617 · Cited by 9
PARP1 mediated PARylation contributes to myogenic progression and glucocorticoid transcriptional response
Tan, A., Younis, A. Z., Evans, A., Creighton, J. V., Coveny, C., Boocock, D. J., Sale, C., Lavery, G. G., Coutts, A. S., & Doig, C. L. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01420-2 · Cited by 10
Role of miRNAs and lncRNAs in dexamethasone‑induced myotube atrophy in vitro
Li, Y., Shi, H., Chen, R., Zhou, S., Lei, S., & She, Y. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9577 · Cited by 9
Testing anabolic activity, potency and mechanisms of action of the phyto-derived beta 2 agonist higenamine
Jiang, L., Piribauer, M., Kostov, T., Steidel, S., Bizjak, D., Steinacker, J., Parr, M., & Diel, P. (2023) · Toxicology Letters · doi:10.1016/j.toxlet.2023.08.007 · Cited by 8
Muscle-Protective Effect of Carnosine against Dexamethasone-Induced Muscle Atrophy in C2C12 Myotube
Rahman, M. M., Ulla, A., Moriwaki, H., YASUKAWA, Y., UCHIDA, T., & Nikawa, T. (2024) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.70.219 · Cited by 8
Aerobic plus resistance exercise attenuates skeletal muscle atrophy induced by dexamethasone through the HDAC4/FoxO3a pathway
Liang, D., Wang, D., Zheng, X., Xiang, H., Liu, S., Yu, C., Tian, J., Ma, J., & Niu, Y. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111581 · Cited by 8
Deferoxamine prevents dexamethasone-induced muscle atrophy by reducing MuRF1 and atrogin-1
Jeong, J.-Y., Son, Y., Kim, Y., Lee, N., Kim, Y., Heo, Y. J., Choi, S., Choi, J., Han, S. J., Jeon, J., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1582216 · Cited by 8
Mineralocorticoid Receptor Signaling in the Inflammatory Skeletal Muscle Microenvironments of Muscular Dystrophy and Acute Injury
Howard, Z. M., Gomatam, C. K., Piepho, A. B., & Rafael‐Fortney, J. A. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.942660 · Cited by 8
Metabolic disorders and post-acute hospitalization in black/mixed-race patients with long COVID in Brazil: A cross-sectional analysis
Barreto, A. P., Filho, M. A. B., Duarte, L. C., Silva, T. C., Camelier, A. A., Tavares, N. M., Barral‐Netto, M., Boaventura, V. S., Lima, M. C. C., & on behalf of the CPC study group (2022) · PLoS ONE · doi:10.1371/journal.pone.0276771 · Cited by 8
Investigating Eukaryotic Elongation Factor 2 Kinase/Eukaryotic Translation Elongation Factor 2 Pathway Regulation and Its Role in Protein Synthesis Impairment during Disuse-Induced Skeletal Muscle Atrophy
Vilchinskaya, N. A., Lim, W. F., Belova, S. P., Roberts, T. C., Wood, M. J. A., & Lomonosova, Y. N. (2023) · American Journal Of Pathology · doi:10.1016/j.ajpath.2023.02.009 · Cited by 8
Metabolic complications of glucocorticoids – Prevention by metformin
Sanpawithayakul, K., & Korbonits, M. (2023) · Annales d Endocrinologie · doi:10.1016/j.ando.2023.05.002 · Cited by 9
Lithium treatment mitigates the diabetogenic effects of chronic cortico-therapy
Delangre, E., Pommier, G., Tolu, S., Uzan, B., Bailbé, D., & Movassat, J. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114895 · Cited by 9
Myasthenia gravis with tongue muscle atrophy: A case series
Zhao, X.-L., Zheng, Y., Yang, C., Wang, J., Liu, Y., Du, T., Zhao, Z.-Y., Duan, R., & Li, X. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e30015 · Cited by 8
The Impact of Ulmus macrocarpa Extracts on a Model of Sarcopenia-Induced C57BL/6 Mice
Lee, C. H., Kwon, Y., Park, S., Kim, T.-H., Kim, M. S., Kim, E. J., Jung, J. I., Min, S., Park, K., Jeong, J. H., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116197 · Cited by 11
GH replacement titrated to serum IGF-1 does not reduce concentrations of myostatin in blood or skeletal muscle
Paul, R. G., McMahon, C. D., Elston, M. S., & Conaglen, J. V. (2018) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2018.12.001 · Cited by 8
The effects of melatonin on neurohormonal regulation in cardiac cachexia: A mechanistic review
Vayghan, H. J., Saleh‐Ghadimi, S., Maleki, V., Moludi, J., & Alizadeh, M. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.29151 · Cited by 8
In Vivo and In Vitro Study of N -Methyltaurine on Pharmacokinetics and Antimuscle Atrophic Effects in Mice
Nguyen, K. H., Ito, S., Maeyama, S., Schaffer, S. W., Murakami, S., & Ito, T. (2020) · ACS Omega · doi:10.1021/acsomega.0c01588 · Cited by 8
Condensed Outpatient Rehabilitation Early After Lung Transplantation: A Retrospective Analysis of 6-Minute Walk Distance and Its Predictors
Byrd, R., Smith, P. J., McHugh, H. F., Snyder, L. D., & Pastva, A. M. (2021) · Cardiopulmonary Physical Therapy Journal · doi:10.1097/cpt.0000000000000174 · Cited by 8
Interaction between retinoic acid and FGF/ERK signals are involved in Dexamethasone-induced abnormal myogenesis during embryonic development
Xu, S., He, X., Shi, J., Li, Z., Song, J., Wang, J., Wang, G., Brand‐Saberi, B., Cheng, X., & Yang, X. (2021) · Toxicology · doi:10.1016/j.tox.2021.152917 · Cited by 8
Design and synthesis of spirocyclic ligands of glucocorticoid receptors
Badarau, E., Robert, F., Massip, S., Jakob, F., Lucas, S., Frormann, S., & Ghosez, L. (2018) · Tetrahedron · doi:10.1016/j.tet.2018.02.030 · Cited by 8
Effect of citrulline on muscle protein turnover in an in vitro model of muscle catabolism
Kuci, O., Archambault, E., Dodacki, A., Nubret, E., Bandt, J. P. D., & Cynober, L. (2019) · Nutrition · doi:10.1016/j.nut.2019.110597 · Cited by 8
Recapitulating pathophysiology of skeletal muscle diseases in vitro using primary mouse myoblasts on a nanofibrous platform
Jain, A., Behera, M., Ravi, V., Mishra, S., Sundaresan, N. R., & Chatterjee, K. (2020) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2020.102341 · Cited by 8
Myostatin and markers of bone metabolism in dermatomyositis
Kerschan‐Schindl, K., Gruther, W., Föger‐Samwald, U., Bangert, C., Kudlacek, S., & Pietschmann, P. (2021) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-021-04030-0 · Cited by 8
6′-sialyllactose prevents dexamethasone-induced muscle atrophy by controlling the muscle protein degradation pathway
Go, H., Sung, N. J., Choi, J., Kim, L., & Park, E. J. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150892 · Cited by 7
EPA-enriched phospholipids and DHA-enriched phospholipids prevent dexamethasone-induced skeletal muscle atrophy via regulating protein turnover and mitochondrial quality
Li, Y.-C., Wu, S.-X., Zou, Q.-Y., Zheng, Y., Wu, Z., Zhao, X., Gao, X., Yang, Y., & Du, L. (2025) · Food Research International · doi:10.1016/j.foodres.2025.117086 · Cited by 7
Regulatory Mechanisms of Muscle Mass: The Critical Role of Resistance Training in Children and Adolescent
Castelli, F., Valero‐Breton, M., Hernandez, M. A., Guarda, F. J., Cornejo, J. G., Cabello‐Verrugio, C., & Cabrera, D. (2022) · Advances in experimental medicine and biology · doi:10.1007/5584_2022_743 · Cited by 7
Glucocorticoid receptor antagonist CORT113176 attenuates motor and neuropathological symptoms of Huntington's disease in R6/2 mice
Gentenaar, M., Meulmeester, F. L., van der Burg, X. R., Hoekstra, A. T., Hunt, H., Kroon, J., van Roon‐Mom, W., & Meijer, O. C. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.114675 · Cited by 7
Current Aspects of Selected Factors to Modulate Brain Health and Sports Performance in Athletes
Przewłócka, K., Korewo-Labelle, D., Berezka, P., Karnia, M. J., & Kaczor, J. J. (2024) · Nutrients · doi:10.3390/nu16121842 · Cited by 9
Adults born preterm have lower peripheral skeletal muscle area and strength
Deprez, A., El-Jalbout, R., Cloutier, A., Gagnon, D. H., Hamelin, A. G., Mathieu, M.-E., Kugathasan, T. A., Dumont, N. A., Nuyt, A. M., & Luu, T. M. (2024) · Scientific Reports · doi:10.1038/s41598-024-72533-6 · Cited by 7
Effects of Fish Meat-derived Peptide and Dipeptides on Dexamethasone-induced Fatigue in Mice
Iwasaki, Y., Sakai, H., Asami, M., Kitora, S., Naito, H., Kon, R., Ikarashi, N., & Kamei, J. (2019) · Journal of Food and Nutrition Research · doi:10.12691/jfnr-7-12-2 · Cited by 7
Strontium gluconate potently promotes osteoblast development and restores bone formation in glucocorticoid-induced osteoporosis rats
Dai, L., Chen, X., Xiong, Y., Chen, J., Li, J., Li, D., Zhou, G., Zou, Y., & Liu, T. (2021) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2021.02.100 · Cited by 7
Body Composition and Maximal Exercise Capacity After Heart Transplantation
Regamey, J., Monney, P. A., Yerly, P., Favre, L., Kirsch, M. E. W., Tozzi, P., Lamy, O., & Hullin, R. (2021) · ESC Heart Failure · doi:10.1002/ehf2.13642 · Cited by 7
Costly immunometabolic remodelling in disused muscle buildup through physical exercise
Padilha, C. S., Figueiredo, C., Deminice, R., Krüger, K., Seelaender, M. C. L., Neto, J. C. R., & Lira, F. S. (2022) · Acta Physiologica · doi:10.1111/apha.13782 · Cited by 7
Influence of COPD systemic environment on the myogenic function of muscle precursor cells in vitro
Casadevall, C., Sancho‐Muñoz, A., Vicente, I., Pascual-Guàrdia, S., Admetlló, M., & Gea, J. (2022) · Respiratory Research · doi:10.1186/s12931-022-02203-6 · Cited by 7
Oral glutamine supplementation relieves muscle loss in immobilized rats, altering p38MAPK and FOXO3a signaling pathways
Petry, É. R., Dresch, D. D. F., Carvalho, C., Medeiros, P. C., Rosa, T. G., de Oliveira, C. M., Martins, L. A. M., Guma, F. T. C. R., Marroni, N. P., & Wannmacher, C. M. D. (2023) · Nutrition · doi:10.1016/j.nut.2023.112273 · Cited by 7
Diagnostic evaluation in steroid-induced myopathy: case report suggesting clinical utility of quantitative muscle ultrasonography
Minetto, M. A., Caresio, C., D’Angelo, V., Lanfranco, F., Ghizzoni, L., Roatta, S., Arvat, E., & Kesari, S. (2018) · Endocrine Research · doi:10.1080/07435800.2018.1461904 · Cited by 7
Leg muscle strength is reduced and is associated with physical quality of life in Antineutrophil cytoplasmic antibody-associated vasculitis
Hessels, A. C., van der Hoeven, J. H., Sanders, J., Brouwer, E., Rutgers, A., & Stegeman, C. A. (2019) · PLoS ONE · doi:10.1371/journal.pone.0211895 · Cited by 7
Chaihu Shugan San Exerts Antidepressant Effects by Regulating Glucocorticoid Metabolism in CUMS Rats and Network Pharmacology Provides Complementary Mechanistic Insights
Xu, Y., Han, X., Zhu, Y., Deng, B., Li, L., Du, Y., Qin, Y., Lv, Y., & Zhai, X. (2025) · ACS Omega · doi:10.1021/acsomega.4c08802 · Cited by 6

Authors: Schakman, O., Kalista, S., Barbé, C., Loumaye, A., & Thissen, J. P.
Affiliations: UCLouvain (BE)
Corresponding author: Thissen, J.P.
ORCID: Schakman, O.
Barbé, C.
Loumaye, A.
Venue: The International Journal of Biochemistry & Cell Biology
Publisher: Elsevier BV
Published: 2013-10
Volume: 45
Issue: 10
Pages: 2163-2172
ISSN: 1357-2725 (ISSN-L)
DOI: 10.1016/j.biocel.2013.05.036
OpenAlex: W2092885411
Cited by: 705
References: 157
Citations by year: 2026: 81 · 2025: 74 · 2024: 58 · 2023: 60 · 2022: 68 · 2021: 62 · 2020: 58 · 2019: 43 · 2018: 44 · 2017: 37 · 2016: 45 · 2015: 48 · 2014: 24 · 2013: 2
FWCI: 3.73
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: The International Journal of Biochemistry & Cell Biology (publishedVersion)
PubMed (publishedVersion)
Digital Access to Libraries (submittedVersion)
Funders: Fund for Scientific Medical Research (Belgium)
National Fund for Scientific Research (Belgium)
Association Française contre les Myopathies (France)
Association Belge contre les Maladies neuro-musculaires
Fonds Spéciaux de Recherche (Université catholique de Louvain, Belgium)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Keywords: glucocorticoid-induced muscle atrophy, skeletal muscle atrophy, muscle protein degradation, ubiquitin-proteasome system, lysosomal proteolysis, atrogenes, atrogin-1, MuRF1, FOXO, muscle protein synthesis, insulin-like growth factor I, myostatin, glucocorticoid-induced myopathy, cachexia, sepsis
MeSH terms: Animals, Glucocorticoids, Humans, Muscular Atrophy, Protein Biosynthesis, Signal Transduction

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Glucocorticoid-induced skeletal muscle atrophy

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks