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Reverting Metabolic Dysfunction in Cortex and Cerebellum of APP/PS1 Mice, a Model for Alzheimer’s Disease by Pioglitazone, a Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Agonist

Chang, K. L., Wong, L. R., Pee, H. N., Yang, S., & Ho, P. C. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1586-2 · Cited by 34 · see citing works

Targeted metabolomics study of early pathological features in hippocampus of triple transgenic Alzheimer’s disease male mice

Zhao, Y., Chen, H., Iqbal, J., Liu, X., Zhang, H., Xiao, S., Jin, N., Yao, F., & Shen, L. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24750 · Cited by 32 · see citing works

Systematic review of brain and blood lipidomics in Alzheimer's disease mouse models

Ferré‐González, L., Lloret, A., & Cháfer‐Pericás, C. (2023) · Progress in Lipid Research · doi:10.1016/j.plipres.2023.101223 · Cited by 29 · see citing works

Status of Metabolomic Measurement for Insights in Alzheimer’s Disease Progression—What Is Missing?

Yin, C., Harms, A. C., Hankemeier, T., Kindt, A. S. D., & de Lange, E. C. M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054960 · Cited by 32 · see citing works

Metabolic Alterations and the Protective Effect of Punicalagin Against Glutamate-Induced Oxidative Toxicity in HT22 Cells

Pathakoti, K., Goodla, L., Manubolu, M., & Tencomnao, T. (2017) · Neurotoxicity Research · doi:10.1007/s12640-016-9697-2 · Cited by 31 · see citing works

Tocotrienol-Rich Fraction of Palm Oil Improves Behavioral Impairments and Regulates Metabolic Pathways in AβPP/PS1 Mice

Durani, L. W., Hamezah, H. S., Ibrahim, N. F., Yanagisawa, D., Nasaruddin, M. L., Mori, M., Azizan, K. A., Damanhuri, H. A., Makpol, S., Ngah, W. Z. W., et al. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170880 · Cited by 31 · see citing works

Brain Lipid Dynamics in Amyloid Precursor Protein/Presenilin 1 Mouse Model of Early Alzheimer’s Disease by Desorption Electrospray Ionization and Matrix Assisted Laser Desorption Ionization–Mass Spectrometry Imaging Techniques

Xue-ju, Z., Wu, C., & Tan, W. (2021) · Journal of Proteome Research · doi:10.1021/acs.jproteome.0c01050 · Cited by 28 · see citing works

High-Throughput Direct Mass Spectrometry-Based Metabolomics to Characterize Metabolite Fingerprints Associated with Alzheimer’s Disease Pathogenesis

González‐Domínguez, R., Sayago, A., & Fernández‐Recamales, Á. (2018) · Metabolites · doi:10.3390/metabo8030052 · Cited by 24 · see citing works

Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice

Raber, J., Perez, R., Torres, E. R. S., Krenik, D., Boutros, S. W., Patel, E. M., Chlebowski, A. C., Torres, E. R., Perveen, Z., Penn, A. L., et al. (2021) · Environmental Health Perspectives · doi:10.1289/ehp8428 · Cited by 19 · see citing works

How far are we from reliable metabolomics-based biomarkers? The often-overlooked importance of addressing inter-individual variability factors

González‐Domínguez, Á., & González‐Domínguez, R. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166910 · Cited by 22 · see citing works

Amelioration of cognitive impairments in APPswe/PS1dE9 mice is associated with metabolites alteration induced by total salvianolic acid

Shen, L., Han, B., Geng, Y., Wang, J., Wang, Z., & Wang, M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0174763 · Cited by 19 · see citing works

Mass spectrometry based analytical approaches and pitfalls for toxicometabolomics of arsenic in mammals: A tutorial review

García‐Barrera, T., Rodríguez‐Moro, G., Leblic, B. C., Arias‐Borrego, A., & Gómez‐Ariza, J. L. (2017) · Analytica Chimica Acta · doi:10.1016/j.aca.2017.10.019 · Cited by 17 · see citing works

Age-related changes in the metabolic profiles of rat hippocampus, medial prefrontal cortex and striatum

Durani, L. W., Hamezah, H. S., Ibrahim, N. F., Yanagisawa, D., Makpol, S., Damanhuri, H. A., & Tooyama, I. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.09.164 · Cited by 17 · see citing works

Mechanistic Insights into Alzheimer’s Disease Unveiled through the Investigation of Disturbances in Central Metabolites and Metabolic Pathways

González‐Domínguez, R., González‐Domínguez, Á., Sayago, A., Sanz, G., Lechuga-Sancho, A. M., & Fernández‐Recamales, Á. (2021) · Biomedicines · doi:10.3390/biomedicines9030298 · Cited by 16 · see citing works

Whole-brain mapping of metabolic alterations in a mouse model of Alzheimer's disease by desorption electrospray ionization mass spectrometry imaging

Wang, X., Yang, X., Hou, Z., Tian, S., Xu, G., Li, J., Wen, L., Bi, D., Gao, F., Shen, Y., et al. (2022) · Talanta · doi:10.1016/j.talanta.2022.124046 · Cited by 14 · see citing works

Establishing a competing endogenous RNA (ceRNA)-immunoregulatory network associated with the progression of Alzheimer’s disease

Li, Y., Shi, H., Chen, T., Xue, J., Wang, C., Peng, M., & Si, G. (2022) · Annals of Translational Medicine · doi:10.21037/atm-21-6762 · Cited by 12 · see citing works

Chronic treatment with baicalein alleviates behavioural disorders and improves cerebral blood flow via reverting metabolic abnormalities in a J20 transgenic mouse model of Alzheimer's disease

Li, Z., Wong, L. R., Wong, P., Shen, W. X., Yang, S., Huang, L., Lim, Y.-A., & Ho, P. C. (2023) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2023.100599 · Cited by 11 · see citing works

Mass Spectrometry-Based Metabolomic Multiplatform for Alzheimer’s Disease Research

González‐Domínguez, R., González‐Domínguez, Á., Sayago, A., & Fernández‐Recamales, Á. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7704-8_8 · Cited by 11 · see citing works

Decreased plasma nicotinamide and altered NAD+ metabolism in glial cells surrounding Aβ plaques in a mouse model of Alzheimer's disease

Sekiya, M., Sakakibara, Y., Hirota, Y., Ito, N., Chikamatsu, S., Takei, K., Nishijima, R., & Iijima, K. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106694 · Cited by 10 · see citing works

Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35

Wei, M., Liu, Y., Pi, Z., Yue, K., Li, S., Hu, M., Liu, Z., Song, F., & Liu, Z. (2019) · RSC Advances · doi:10.1039/c9ra00302a · Cited by 10 · see citing works

High-Throughput Metabolomics Based on Direct Mass Spectrometry Analysis in Biomedical Research

González‐Domínguez, R., González‐Domínguez, Á., Segundo, C., Schwarz, M., Sayago, A., Mateos, R. M., Durán, E., Lechuga-Sancho, A. M., & Fernández‐Recamales, Á. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9236-2_3 · Cited by 9 · see citing works

Early Effect of Amyloidβ-Peptide on Hippocampal and Serum Metabolism in Rats Studied by an Integrated Method of NMR-Based Metabolomics and ANOVA-Simultaneous Component Analysis

Du, Y., Zheng, H. X., Xia, H., Zhao, L., Hu, W., Bai, G., Yan, Z., & Gao, H. (2017) · BioMed Research International · doi:10.1155/2017/3262495 · Cited by 8 · see citing works

The Impact of the Exposome on Alzheimer’s Disease: The Influence of Nutrition

Monaco, M., Torazza, C., Fedele, E., & Grilli, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073015 · Cited by 7 · see citing works

Laser Activated Electron Tunneling Based Mass Spectrometric Imaging of Molecular Architectures of Mouse Brain Revealing Regional Specific Lipids

Huang, L., Tang, X., Zhang, W., Jiang, R., & Zhong, H. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b02871 · Cited by 7 · see citing works

Small molecule biomarkers in Alzheimer’s disease

Kim, M. G., & Legido‐Quigley, C. (2018) · OCL · doi:10.1051/ocl/2018027 · Cited by 7 · see citing works

Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method

Xiao, S., Wei, X., Han, B., Shi, X., Wei, C., Liang, R., Sun, J., Zhang, Z., Han, Z., & Shen, L. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1561831 · Cited by 6 · see citing works

Analysis and Annotation of Phospholipids by Mass Spectrometry-Based Metabolomics

González‐Domínguez, Á., Santos-Martín, M., Sayago, A., Lechuga-Sancho, A. M., Fernández‐Recamales, Á., & González‐Domínguez, R. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2966-6_7 · Cited by 5 · see citing works

Plasma lipidomics in early APP/PS1 female mouse model and its relationship with brain: Is it affected by the estrous cycle?

Ferré‐González, L., Balaguer, Á., Roca, M., Ftara, A., Lloret, A., & Cháfer‐Pericás, C. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01549-x · Cited by 4 · see citing works

Metabolomic Fingerprinting of Blood Samples by Direct Infusion Mass Spectrometry: Application in Alzheimer’s Disease Research

González‐Domínguez, R. (2017) · Journal of Analysis and Testing · doi:10.1007/s41664-017-0018-4 · Cited by 3 · see citing works

Correction to: Metabolomic Fingerprinting of Blood Samples by Direct Infusion Mass Spectrometry: Application in Alzheimer’s Disease Research

González‐Domínguez, R. (2017) · Journal of Analysis and Testing · doi:10.1007/s41664-017-0041-5 · Cited by 2 · see citing works

State-of-the-art Mass Spectrometry-based Approaches to Explore the Polar Metabolome: Alzheimer's Disease as a Case Study

González‐Domínguez, R., González‐Domínguez, Á., Sayago, A., & Fernández‐Recamales, Á. (2021) · Royal Society of Chemistry eBooks · doi:10.1039/9781839163524-00219 · Cited by 1 · see citing works

Multicompartmental High-Throughput Metabolomics Based on Mass Spectrometry

González‐Domínguez, R., González‐Domínguez, Á., Sayago, A., & Fernández‐Recamales, Á. (2020) · Neuromethods · doi:10.1007/978-1-0716-0864-7_15 · Cited by 1 · see citing works

Correction: Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer’s disease rat induced by amyloid beta 25-35

Wei, M., Liu, Y., Pi, Z., Yue, K., Li, S., Hu, M., Liu, Z., Song, F., & Liu, Z. (2021) · RSC Advances · doi:10.1039/d1ra90081a

Mass Spectrometry-Based Metabolomics Multi-platform for Alzheimer’s Disease Research

González‐Domínguez, Á., Sayago, A., Fernández‐Recamales, Á., & González‐Domínguez, R. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-3774-6_6

Metabolomics tools for the analysis of phospholipids as potential markers to decipher the molecular mechanisms behind diseases

González‐Domínguez, Á., Jurado‐Sumariva, L., Sayago, A., Schwarz, M., Fernández‐Recamales, Á., Durán, E., & González‐Domínguez, R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-19116-9.00012-9

Peripheral Indicators of Alzheimer’s Disease Pathology in Women With Polycystic Ovary Syndrome: A Case–Control Study

Xing, B., Xiaoqing, P., & Yan, Z. (2026) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/cjn.2025.10495

The Environmental Contribution to Health and Disease: Analytical Tools for Monitoring and Diagnosis

Aranda‐Merino, N., Heras, C. G. D. L., Ramos‐Payán, M., Fernández‐Torres, R., Bello‐López, M. Á., & Gómez‐Ariza, J. L. (2026) · Environments · doi:10.3390/environments13080416

Metabolomic screening of regional brain alterations in the APP/PS1 transgenic model of Alzheimer's disease by direct infusion mass spectrometry

González‐Domínguez, R., García‐Barrera, T., Vitórica, J., & Gómez‐Ariza, J. L. (2014) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2014.10.009 · Cited by 92 · see citing works

Application of metabolomics based on direct mass spectrometry analysis for the elucidation of altered metabolic pathways in serum from the APP/PS1 transgenic model of Alzheimer's disease

González‐Domínguez, R., García‐Barrera, T., Vitórica, J., & Gómez‐Ariza, J. L. (2015) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2015.01.025 · Cited by 53 · see citing works

Metabolomic investigation of systemic manifestations associated with Alzheimer's disease in the APP/PS1 transgenic mouse model

González‐Domínguez, R., García‐Barrera, T., Vitórica, J., & Gómez‐Ariza, J. L. (2015) · Molecular BioSystems · doi:10.1039/c4mb00747f · Cited by 50 · see citing works

Region-specific metabolic alterations in the brain of the APP/PS1 transgenic mice of Alzheimer's disease

González‐Domínguez, R., García‐Barrera, T., Vitórica, J., & Gómez‐Ariza, J. L. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.09.014 · Cited by 96 · see citing works

Application of a metabolomic multiplatform to investigate Alzheimer's disease pathogenesis

González‐Domínguez, R. (2016) · International Electronic Conference on Metabolomics (IECM) · doi:10.3390/iecm-1-a003