Cited by 897Deep Brain Stimulation and Movement DisordersObsessive-Compulsive Spectrum DisordersTreatment of Major Depression

The DOI matches its Crossref record; 38 of the 39 references it cites were found in a registry or an index.

Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression

Open access

Malone, Donald A., Dougherty, Darin D., Rezai, Ali R., Carpenter, Linda L., Friehs, Gerhard M., Eskandar, Emad N., Rauch, Scott L., Rasmussen, Steven A., Machado, Andre G., Kubu, Cynthia S., Tyrka, Audrey R., Price, Lawrence H., Stypulkowski, Paul H., Giftakis, Jonathon E., Rise, Mark T., Malloy, Paul F., Salloway, Stephen P., Greenberg, Benjamin D.·2009·Biological Psychiatry

DOI 10.1016/j.biopsych.2008.08.029PMC PMC3486635

Open this paper in CoChat — free account

Abstract

Background We investigated the use of deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) for treatment refractory depression.Methods Fifteen patients with chronic, severe, highly refractory depression received open-label DBS at three collaborating clinical sites. Electrodes were implanted bilaterally in the VC/VS region. Stimulation was titrated to therapeutic benefit and the absence of adverse effects. All patients received continuous stimulation and were followed for a minimum of 6 months to longer than 4 years. Outcome measures included the Hamilton Depression Rating Scale-24 item (HDRS), the Montgomery-Asberg Depression Rating Scale (MADRS), and the Global Assessment of Function Scale (GAF).Results Significant improvements in depressive symptoms were observed during DBS treatment. Mean HDRS scores declined from 33.1 at baseline to 17.5 at 6 months and 14.3 at last follow-up. Similar improvements were seen with the MADRS (34.8, 17.9, and 15.7, respectively) and the GAF (43.4, 55.5, and 61.8, respectively). Responder rates with the HDRS were 40% at 6 months and 53.3% at last follow-up (MADRS: 46.7% and 53.3%, respectively). Remission rates were 20% at 6 months and 40% at last follow-up with the HDRS (MADRS: 26.6% and 33.3%, respectively). The DBS was well-tolerated in this group.Conclusions Deep brain stimulation of the VC/VS offers promise for the treatment of refractory major depression.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.biopsych.2008.08.029

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report
Rush, A. J., Trivedi, M. H., Wisniewski, S. R., Nierenberg, A. A., Stewart, J. W., Warden, D., Niederehe, G., Thase, M. E., Lavori, P. W., Lebowitz, B. D., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.11.1905 · Cited by 5,643
Research confuses me: what is the difference between case-control and cohort studies in quantitative research?
Higgins, S. M. F., Macken, A. P., Cullen, W., Saunders, J., Dunne, C. P., & O’Gorman, C. S. (2013) · PubMed · doi:10.34961/9953 · Cited by 4,807
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Reciprocal Limbic-Cortical Function and Negative Mood: Converging PET Findings in Depression and Normal Sadness
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416
Deep Brain Stimulation to Reward Circuitry Alleviates Anhedonia in Refractory Major Depression
Schlaepfer, T. E., Cohen, M. X., Frick, C., Kosel, M., Brodesser, D., Axmacher, N., Joe, A. Y., Kreft, M., Lenartz, D., & Sturm, V. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301408 · Cited by 1,027
Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: worldwide experience
Greenberg, B. D., Gabriels, L. A., Malone, D. A., Rezai, A. R., Friehs, G. M., Okun, M. S., Shapira, N. A., Foote, K. D., Cosyns, P. R., Kubu, C. S., et al. (2010) · Molecular Psychiatry · doi:10.1038/mp.2008.55 · Cited by 867
Self-citation
Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder
Nuttin, B., Cosyns, P. R., Demeulemeester, H. G., Gybels, J., & Meyerson, B. A. (1999) · The Lancet · doi:10.1016/s0140-6736(99)02376-4 · Cited by 854
Three-Year Outcomes in Deep Brain Stimulation for Highly Resistant Obsessive–Compulsive Disorder
Greenberg, B. D., Malone, D. A., Friehs, G. M., Rezai, A. R., Kubu, C. S., Malloy, P. F., Salloway, S., Okun, M. S., Goodman, W. K., & Rasmussen, S. A. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301165 · Cited by 835
Self-citation
Neuroimaging and frontal–subcortical circuitry in obsessive–compulsive disorder
Saxena, S., Brody, A. L., Schwartz, J. M., & Baxter, L. R. (1998) · British Journal of Psychiatry · doi:10.1192/s0007125000297870 · Cited by 831

Show all 39 references

Research works printed but not linked: 2

Herner, 1961, Treatment of mental disorders with frontal stereotactic thermo-lesions: A follow-up of 116 cases, Acta Psychiatr Scand Suppl, 36, 941
Kubu, 2008, Cognitive effects of DBS in the ventral striatum in patients with severe major depression and obsessive-compulsive disorder, Biol Psychiatry, 63, 232S

Sorted by citations

Items 801–890 of 890

Deep Brain Stimulation Suppresses Gamma Oscillations in Treatment Resistant Depression
Sun, Y. (2012) · TSpace (University of Toronto)
The Costs and Benefits of Deep Brain Stimulation Surgery for Patients with Parkinson’s Disease at Different Stages of Severity – An Initial Exploration
Ng, V. W. M. (2013) · TSpace (University of Toronto)
Deep Brain Stimulation: A Promising Therapeutic Approach to the Treatment of Severe Depressed Patients — Current Evidence and Intrinsic Mechanisms
Pérez-Caballero, L., Torres-Sánchez, S., Micó, J. A., & Berrocoso, E. (2017) · Springer eBooks · doi:10.1007/978-3-319-53126-7_19
The Electrode – Principles of the Neural Interface
Montgomery, E. B. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-381409-8.00008-5
Neuromodulation for Non-urologic Chronic Pain
Staudt, M. D., & Miller, J. P. (2018) · Springer eBooks · doi:10.1007/978-3-319-73266-4_2
Cortical Stimulation for Depression
Gilligan, J. T., Rasouli, J. J., & Kopell, B. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805353-9.00092-9
Experimental and Model-based Approaches to Directional Thalamic Deep Brain Stimulation
Xiao, J. (2016) · University of Minnesota Digital Conservancy (University of Minnesota)
Brain Stimulation Therapy in Psychiatry
Hall, S. E. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-385157-4.01064-2
Vom experimentellen Ansatz zur wirksamen Therapieoption
Bajbouj, M. (2013) · InFo Neurologie + Psychiatrie · doi:10.1007/s15005-013-0304-2
Neuromodulation mit der Vagusnervstimulation und der tiefen Hirnstimulation bei der therapierefraktären Depression: Auf dem Weg zu einer Differentialindikation
Baumann‐Vogel, H., Sürücü, O., Baumann, C. R., & Böker, H. (2014) · Schweizer Archiv für Neurologie und Psychiatrie · doi:10.4414/sanp.2014.00290
Deep Brain Stimulation: Mechanisms Underpinning Antidepressant Effects
Torres-Sánchez, S., Pérez-Caballero, L., & Berrocoso, E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813333-0.00033-0
Deep Brain Stimulation for the Treatment of Resistant Depression: Systematic Review of the Literature
Julião, Í. E. G. S., Santana, D. F., & da Silva, L. J. (2019) · Arquivos Brasileiros de Neurocirurgia Brazilian Neurosurgery · doi:10.1055/s-0039-1692158
Deep brain stimulation for major depression: A prototype of a personalized treatment in psychiatry
Schlaepfer, T. E., & Bewernick, B. H. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813176-3.00008-0
Awake Testing to Confirm Target Engagement
Patel, N., Gavvala, J. R., & Shahed, J. J. (2020) · Springer eBooks · doi:10.1007/978-3-030-34906-6_10
Development of brain stimulation
Crowell, A. L., Riva‐Posse, P., & Mayberg, H. S. (2020) · doi:10.1093/med/9780198713005.003.0019
Nachhaltige antidepressive Effekte
Plewnia, C. (2012) · InFo Neurologie + Psychiatrie · doi:10.1007/s15005-012-0509-9
Brain-Machine Interfaces for Closed-Loop Electrical Brain Stimulation in Neuropsychiatric Disorders
Sani, O. G., Yang, Y., & Shanechi, M. M. (2021) · Handbook of Neuroengineering · doi:10.1007/978-981-15-2848-4_107-1
Role of Deep Brain Stimulation in Treatment Resistant Depression: A Review Article
Khoshnevisan, A. (2021) · Psychology and Psychotherapy Research Study · doi:10.31031/pprs.2021.04.000598
Sex differences in depression susceptibility are modulated by circuit function and Eph receptor signaling
Thériault, R.-K. (2021) · The Atrium (University of Guelph) · doi:10.1503/jpn.200117
Decoding task states from distributed local field potential recordings
Provenza, N. R. (2017) · doi:10.7301/z0348htc
Faculty Opinions recommendation of Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex.
Hen, R. (2011) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.7494957.7789055
Mechanisms and Targeting of Deep-Brain Stimulation Therapies
Brinda, A. K., & Johnson, M. D. (2022) · Handbook of Neuroengineering · doi:10.1007/978-981-15-2848-4_133-1
Psychosurgical Procedures
Lévêque, M. (2014) · Springer eBooks · doi:10.1007/978-3-319-01144-8_3
Does Closed-Loop DBS for Treatment of Psychiatric Disorders Raise Salient Authenticity Concerns?
Dasgupta, I., Schönau, A., Brown, T., Klein, E. P., & Goering, S. (2021) · Advances in neuroethics · doi:10.1007/978-3-030-74188-4_14
Elektrokonvulsionstherapie, Hirnstimulationsverfahren
Kreuzer, P. M., Jooyandeh, S. M., Langguth, B., Kranz, G. S., Padberg, F., Kasper, S. F., & Baghai, T. C. (2017) · Springer Reference Medizin · doi:10.1007/978-3-642-45028-0_32-2
Hirnstimulationsverfahren
Schläpfer, T. E., & Kayser, S. (2011) · Springer eBooks · doi:10.1007/978-3-642-19844-1_63
Faculty Opinions recommendation of Six-Nine Year Follow-Up of Deep Brain Stimulation for Obsessive-Compulsive Disorder.
Mallet, L. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.727085714.793546314
Estudo randomizado, fase II, duplamente coberto, de estimulação elétrica bilateral subcutânea do nervo trigêmeo para o tratamento de depressão maior unipolar - TREND
Gorgulho, A. A. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2022.tde-08042022-123137
Author Index to Volume 65
(2009) · Biological Psychiatry · doi:10.1016/s0006-3223(09)00559-9
Neuromodulation and Psychiatric Disorders
Goodman, W. K., & George, M. S. (2017) · Oxford University Press eBooks · doi:10.1093/med/9780190681425.003.0010
DBS
Ward, W. K. (2017) · Springer eBooks · doi:10.1007/978-981-287-104-6_100074
Deep Brain Stimulation for Highly Refractory Depression
Dougherty, D. D., Widge, A. S., & Greenberg, B. D. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805353-9.00087-5
Self-citation
Bibliography: for Psychopharmacology: Treatment-Resistant Disorders
(2010) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.8.4.foc550
Neuropsychological Considerations for Parkinson’s Disease Patients Being Considered for Surgical Intervention with Deep Brain Stimulation
Mattis, P. J., Fridman, C. B., & Meltzer, E. P. (2019) · Clinical handbooks in neuropsychology · doi:10.1007/978-3-319-93497-6_35
Deep Brain Stimulation for Patients with Eating Disorders
Ward, W. K. (2016) · Springer eBooks · doi:10.1007/978-981-287-087-2_208-1
Deep Brain Stimulation for Treatment-Resistant Mental Illness
Widge, A. S. (2022) · Psychiatric Annals · doi:10.3928/00485713-20220621-02
Brain-Machine Interface: Overview
Oweiss, K. G. (2022) · Springer eBooks · doi:10.1007/978-1-0716-1006-0_783
Deep Brain Stimulation and memory restoration
Liu, H. (2022) · doi:10.26481/dis.20221003hl
Brain-Machine Interface: Overview
Oweiss, K. G. (2015) · Springer eBooks · doi:10.1007/978-1-4614-6675-8_783
Current state of knowledge concerning experimental applications for deep brain stimulation in specific neurologic and psychiatric disorders
Senger, M., DORUCH, P., & Kędziora–Kornatowska, K. (2022) · Journal of Education Health and Sport · doi:10.12775/jehs.2022.12.12.042
Cerebral—deep
Mackel, C. E., Gologorsky, Y., & Alterman, R. L. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-817000-7.00003-x
Deep Brain Stimulation-Emerging Indications and Newer Techniques: A Current Perspective
Moidu, F., & Ovallath, S. (2022) · International Neuropsychiatric Disease Journal · doi:10.9734/indj/2022/v18i3356
Use of deep brain stimulation for treatment-resistant depression – review of main stimulation targets
Tokarzewska, A., Orczyk, J., OŁOWNIA, A., & Małyszek, M. (2023) · Journal of Education Health and Sport · doi:10.12775/jehs.2023.13.05.002
Elektrisch evenwicht
van der Linden, M. A. (2023) · Utrecht University Repository (Utrecht University) · doi:10.33540/1684
An editorial view on restoring the balance of intestinal microbiota and its relevance to most of the neuropsychiatric disorders
Oprea, G., Ghidersa, M., Balmus, I. M., Mavroudis, I. A., Ciobica, A. S., & Cîmpeanu, M. (2023) · Bulletin of Integrative Psychiatry · doi:10.36219/bpi.2023.1.03
Depression and Bipolar Affective Disorder
Zheng, Z., Zou, K., Huang, J., Bao, T., & Han, J. (2023) · Springer eBooks · doi:10.1007/978-981-99-4538-2_18
Estado del arte: nuevas aplicaciones para la estimulación cerebral profunda.
Roy, H., Green, A. L., & Aziz, T. Z. (2018) · NeuroTarget · doi:10.47924/neurotarget2018128
Mechanisms of deep brain stimulation for psychiatric disorders
Brusco, C., Feigen, C. M., & Eskandar, E. N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18496-3.00017-3
Self-citation
Deep brain stimulation for depression
Kitay, B. M., & Riva‐Posse, P. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18496-3.00019-7
Neuromodulation in Psychiatry
Davani, A. J., Richardson, A. J. W., Vodovozov, W., & Sanghani, S. N. (2024) · Advances in Psychiatry and Behavioral Health · doi:10.1016/j.ypsc.2024.05.013
Brain Structures Involved in Major Depressive Disorder
Bennett, M. R. (2024) · Springer eBooks · doi:10.1007/978-981-97-2803-9_8
The role of MRgFUS in the treatment of neuropsychiatric disorders: a state of the art
Campisi, B. M., Costanzo, R., Noto, M., Cipollina, G. P., MARINO, S., Lorenzo, G. D., Bonosi, L., Brunasso, L., Iacopino, D. G., & Maugeri, R. (2024) · Journal of Neurosurgical Sciences · doi:10.23736/s0390-5616.24.06306-9
Other Biological Treatments Used in Depression
Demir, B., & Dönmezdil, S. (2024) · doi:10.69860/nobel.9786053359456.5
How Does Brain Stimulation Work? Neuroversion and Other Putative Mechanisms of Action
(2024) · Frontiers research topics · doi:10.3389/978-2-8325-5538-5
Literaturverzeichnis zu Voderholzer (Hrsg.): Therapie psychischer Erkrankungen, 20. Auflage
(2024) · Elsevier eBooks · doi:10.1016/b978-3-437-21224-6.00055-4
References
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.bm01
Chapter 9. Cognitive Effects of ECT
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg09
Chapter 4. The Pre-ECT Medical Workup
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg04
Chapter 2. Patient Selection for ECT
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg02
Chapter 3. Patient Education and Informed Consent for ECT
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg03
Chapter 1. Introduction to ECT
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg01
Chapter 10. ECT Versus Other Neuropsychiatric Treatments
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg10
Chapter 6. ECT Technique, Part I: Managing the Individual Treatment
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg06 · Cited by 1
Index
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.index
Chapter 5. Anesthesia for ECT
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg05
Chapter 8. Preventing Relapse After ECT: Maintenance ECT and Pharmacotherapy
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg08
Chapter 7. ECT Technique, Part II: Managing the Course of Treatments
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.lg07
Front Matter
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615379422.fm01
Neurotechnologies in Anxiety and Depression
Chaudhary, U. (2025) · Springer eBooks · doi:10.1007/978-3-031-78991-5_7
Cariprazine modulates affective and social behaviors through ventral striatal islands of Calleja neurons
Song, Z.-W., Wang, W., Wang, H., Zhong, Y., Li, G., Tan, R., & Zhang, Y. F. (2025) · Current Zoology · doi:10.1093/cz/zoaf034
Brain-Computer Interface Technology for Emotion Recognition and Social Cue Analysis in Individuals With Neurological and Mental Health Disorders
Jain, A., Shantha, V., & Veena, N. (2025) · Advances in computational intelligence and robotics book series · doi:10.4018/979-8-3373-5072-1.ch012
Neurochemical mechanisms of deep brain stimulation
Liu, H., Witzig, V. S., Tan, S. K. H., & Hescham, S. (2025) · Deep Brain Stimulation · doi:10.1016/j.jdbs.2025.08.002
Deep brain stimulation for treatment-resistant depression
Riva‐Posse, P. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824067-0.00022-0
Les interventions de psychochirurgie
Lévêque, M. (2013) · Springer eBooks · doi:10.1007/978-2-8178-0454-5_3
Postmortem Dissections of Common Targets for Deep Brain Stimulation for Parkinson’s Disease, Dystonia, and Obsessive-Compulsive Disorder
Holanda, V. M., Middlebrooks, E. H., & Santiago, N. (2025) · Springer eBooks · doi:10.1007/978-3-031-95119-0_16
The effects of deep brain stimulation on neurochemistry
Hescham, S., Liu, H., Witzig, V. S., & Tan, S. K. H. (2026) · Elsevier eBooks · doi:10.1016/b978-0-323-99742-3.00006-0
Neurorestorative and neuroimmune effects of deep brain stimulation
Campos, A. C. P., Pagano, R. L., & Hamani, C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-323-99742-3.00003-5
Epigenetic regulation of BDNF-TRKB signaling in the pathophysiology and treatment of mood disorders
Boulle, F. (2013) · theses.fr (ABES) · doi:10.70675/7796cc83z9f91z48c6zadb1zb6a90897b5d5
When anatomy drives physiology : expanding the actor-critic model of the basal ganglia to new subthalamus connections
Haynes, W. I. A. (2014) · theses.fr (ABES) · doi:10.70675/bc75d92dz55b5z447azbb70z2e28f320b4e7
Validation d'une nouvelle électrode hybride intracérébrale comportant des tétrodes dans l'épilepsie pharmaco-résistante
Despouy, E. (2019) · theses.fr (ABES) · doi:10.70675/5903e0fdz9e05z4aa9z8acazb5f1f807aff8
Medial forebrain bundle deep brain stimulation in a rodent model of depression : modulation of sleep abnormalities and mechanisms of anti-depressant effects
Gardner, W. (2021) · theses.fr (ABES) · doi:10.70675/ad8c62bdza271z421eza82ez2615d4e0056d
Advances in the Clinical Application of Neurostimulation in Major Depression
Göke, K., Kaster, T. S., & Blumberger, D. M. (2026) · Advances in experimental medicine and biology · doi:10.1007/978-981-95-6872-7_28
Deep brain stimulation for major depressive disorder: a systematic review and meta-analysis
Manocchio, F., Profant, M. R., Abbasian, A., Enepekides, J., Rabin, J. S., Goubran, M., Meng, Y., Cao, X., Nestor, S. M., Hamani, C., et al. (2026) · Nature Mental Health · doi:10.1038/s44220-026-00725-2
Differential response to deep brain stimulation in harm-avoidant vs. disgust subtypes of obsessive-compulsive disorderPreprint
Hamre, T. A., Kutcher, T., Hanish, R. R., Soubra, S. S., Bentley, H., Mansourian, K. A., Nitcheu, G. L. T., Belavadi, V., Chamarthi, S., Jourahmad, Z., et al. (2026) · medRxiv · doi:10.64898/2026.07.20.26357997
Long-term cognitive effects after SCG-DBS in patients with treatment resistant depression: A 5-year follow-up
Vicent-Gil, M., Trujols, J., Puigdemont, D., Portella, M. J., Alemany, C., Serrano-Gimeno, V., Aibar‐Durán, J. Á., Rodríguez, R. R., Ros, E., Cofán, M., et al. (2026) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2026.111882
Use of neurostimulation in patients with treatment-resistant depression: current options and future directions
Noda, Y. (2026) · Expert Review of Medical Devices · doi:10.1080/17434440.2026.2717170
Neuromodulation for pain in children
Shahin, M. N., & Raskin, J. S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-23540-5.00017-5
Cortical evoked potentials from deep brain stimulation of the superolateral medial forebrain bundle: An exploratory study
Pereira, J., Dold, M., Sajonz, B., Reinacher, P. C., Jarc, N., Czornik, M., Baldermann, J. C., Schlaepfer, T. E., Reisert, M., Tangermann, M., et al. (2026) · Clinical Neurophysiology · doi:10.1016/j.clinph.2026.2112451
Vraies et fausses innovations en psychiatrie
Dardennes, R. M., & Anbar, N. N. A. (2012) · Springer eBooks · doi:10.1007/978-2-8178-0299-2_8
Sonstige biologische Therapieverfahren – Theoretische und empirische Grundlagen sowie klinische Anwendungsprinzipien
Kasper, S. F., Baghai, T. C., & Padberg, F. (2011) · Springer eBooks · doi:10.1007/978-3-642-03637-8_29

Authors: Malone, D. A., Dougherty, D. D., Rezai, A. R., Carpenter, L. L., Friehs, G. M., Eskandar, E. N., Rauch, S. L., Rasmussen, S. A., Machado, A. G., Kubu, C. S., Tyrka, A. R., Price, L. H., Stypulkowski, P. H., Giftakis, J. E., Rise, M. T., Malloy, P. F., Salloway, S. P., & Greenberg, B. D.
Affiliations: Cleveland Clinic (US)
McLean Hospital (US)
Butler Hospital (US)
Brown University (US)
Massachusetts General Hospital (US)
Medtronic (United States) (US)
Corresponding author: Malone, Donald A.
ORCID: Dougherty, Darin D.
Rezai, Ali R.
Carpenter, Linda L.
Eskandar, Emad N.
Rauch, Scott L.
Rasmussen, Steven A.
Kubu, Cynthia S.
Tyrka, Audrey R.
Price, Lawrence H.
Giftakis, Jonathon E.
Salloway, Stephen P.
Greenberg, Benjamin D.
Venue: Biological Psychiatry
Publisher: Elsevier BV
Published: 2009-02
Volume: 65
Issue: 4
Pages: 267-275
ISSN: 0006-3223 (ISSN-L)
DOI: 10.1016/j.biopsych.2008.08.029
PMC: PMC3486635
OpenAlex: W2014786844
Cited by: 897
References: 39
Citations by year: 2026: 16 · 2025: 20 · 2024: 41 · 2023: 46 · 2022: 37 · 2021: 38 · 2020: 34 · 2019: 51 · 2018: 45 · 2017: 57 · 2016: 58 · 2015: 70 · 2014: 70 · 2013: 64 · 2012: 81
FWCI: 35.18
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (5p50mh086400-05)
National Institute of Mental Health (P-50-MH-086400)
National Eye Institute (R01EY017658)
Topics: Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords: deep brain stimulation, ventral capsule/ventral striatum, treatment-resistant depression, depression remission, long-term outcomes
MeSH terms: Adolescent, Adult, Chronic Disease, Cognition, Depressive Disorder, Drug Resistance, Electrodes, Implanted, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Recurrence, Treatment Outcome, Neostriatum, Deep Brain Stimulation, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks