Pharmacogenetic Randomized Trial for Cocaine Abuse: Disulfiram and Dopamine β-Hydroxylase

R: A Language and Environment for Statistical Computing

R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,706 · see citing works

Inference of Population Structure Using Multilocus Genotype Data

Pritchard, J. K., Stephens, M., & Donnelly, P. (2000) · Genetics · doi:10.1093/genetics/155.2.945 · Cited by 33,871 · see citing works

Inferring weak population structure with the assistance of sample group information

HUBISZ, M. J., FALUSH, D., STEPHENS, M., & PRITCHARD, J. K. (2009) · Molecular Ecology Resources · doi:10.1111/j.1755-0998.2009.02591.x · Cited by 3,475 · see citing works

An Improved Diagnostic Evaluation Instrument for Substance Abuse Patients

McLellan, A. T., Luborsky, L. B., WOODY, G. E., & Brien, C. P. O. (1980) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198001000-00006 · Cited by 3,163 · see citing works

Drug Dependence, a Chronic Medical Illness

McLellan, A. T., Lewis, D. C., O'Brien, C. P., & Kleber, H. D. (2000) · JAMA · doi:10.1001/jama.284.13.1689 · Cited by 2,622 · cited 6× · see citing works

Addiction Is a Brain Disease, and It Matters

Leshner, A. I. (1997) · Science · doi:10.1126/science.278.5335.45 · Cited by 1,615 · see citing works

The genetics of addictions: uncovering the genes

Goldman, D., Oroszi, G., & Ducci, F. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1635 · Cited by 1,099 · see citing works

Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients

Carroll, K. M., Fenton, L. R., Ball, S. A., Nich, C., Frankforter, T. L., Shi, J. M., & Rounsaville, B. J. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.3.264 · Cited by 410 · see citing works

Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram

Carroll, K. M., Nich, C., Ball, S. A., McCance, E. F., & Rounsavile, B. J. (1998) · Addiction · doi:10.1046/j.1360-0443.1998.9357137.x · Cited by 375 · see citing works

Dopamine supersensitivity correlates with D2 High states, implying many paths to psychosis

Seeman, P. M., Weinshenker, D., Quirion, R., Srivastava, L. K., Bhardwaj, S. K., Grandy, D. K., Premont, R. T., Sotnikova, T. D., Boksa, P., El-Ghundi, M., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409766102 · Cited by 353 · see citing works

There and Back Again: A Tale of Norepinephrine and Drug Addiction

Weinshenker, D., & Schroeder, J. P. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301263 · Cited by 347 · see citing works

Clinical Guidelines for Psychiatrists for the Use of Pharmacogenetic Testing for CYP450 2D6 and CYP450 2C19

de León, J., Armstrong, S. C., & Cozza, K. L. (2005) · Psychosomatics · doi:10.1176/appi.psy.47.1.75 · Cited by 300 · see citing works

Pharmacogenetics of Psychotropic Drug Response

Malhotra, A. K., Murphy, G. M., & Kennedy, J. L. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.5.780 · Cited by 298 · see citing works

Pharmacogenetics of Antidepressant Medication Intolerance

Murphy, G. M., Kremer, C. M. E., Rodrigues, H. E., & Schatzberg, A. F. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.10.1830 · Cited by 284 · see citing works

A Quantitative-Trait Analysis of Human Plasma–Dopamine β-Hydroxylase Activity: Evidence for a Major Functional Polymorphism at the DBH Locus

Zabetian, C. P., Anderson, G., Buxbaum, S. G., Elston, R. C., Ichinose, H., Nagatsu, T., Kim, K., Kim, C., Malison, R. T., Gelernter, J. E., et al. (2001) · The American Journal of Human Genetics · doi:10.1086/318198 · Cited by 268 · see citing works

How important is treatment? One-year outcomes of treated and untreated alcohol-dependent individuals.

Weisner, C., Matzger, H., & Kaskutas, L. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00438.x · Cited by 247 · see citing works

A National 5-Year Follow-up of Treatment Outcomes for Cocaine Dependence

Simpson, D. D., Joe, G. W., & Broome, K. M. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.6.538 · Cited by 243 · see citing works

Disulfiram treatment for cocaine dependence in methadone‐maintained opioid addicts

Petrakis, I. L., Carroll, K. M., Nich, C., Gordon, L. T., McCance‐Katz, E. F., Frankforter, T. L., & Rounsaville, B. J. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.9522198.x · Cited by 229 · see citing works

Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450–metabolized drugs

Rogers, J. F., Nafziger, A. N., & Bertino, J. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01363-3 · Cited by 217 · see citing works

Proportioning whole-genome single-nucleotide-polymorphism diversity for the identification of geographic population structure and genetic ancestry.

Lao, O., van Duijn, K., Kersbergen, P., de Knijff, P., & Kayser, M. (2006) · American Journal of Human Genetics · doi:10.1086/501531 · Cited by 192 · see citing works

A haplotype at the DBH locus, associated with low plasma dopamine β-hydroxylase activity, also associates with cocaine-induced paranoia

Cubells, J. F., Kranzler, H. R., McCance‐Katz, E. F., Anderson, G. M., Malison, R. T., Price, L. H., & Gelernter, J. E. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000657 · Cited by 179 · see citing works

Serum Dopamine-β-Hydroxylase Activity: Sibling-Sibling Correlation

Weinshilboum, R. M., Raymond, F. A., Elveback, L. R., & Weidman, W. H. (1973) · Science · doi:10.1126/science.181.4103.943 · Cited by 175 · see citing works

Concentrations of monoamine metabolites in the cerebrospinal fluid of twins and unrelated individuals—A genetic study

Oxenstierna, G., Edman, G., Iselius, L., Oreland, L., Ross, S. B., & Sedvall, G. (1986) · Journal of Psychiatric Research · doi:10.1016/0022-3956(86)90020-8 · Cited by 174 · see citing works

Heroin use during methadone maintenance treatment: the importance of methadone dose and cocaine use.

Hartel, D. M., Schoenbaum, E. E., Selwyn, P. A., Kline, J. D., Davenny, K., Klein, R. S., & Friedland, G. H. (1995) · American Journal of Public Health · doi:10.2105/ajph.85.1.83 · Cited by 169 · see citing works

Human genetics of plasma dopamine ?-hydroxylase activity: applications to research in psychiatry and neurology

Cubells, J. F., & Zabetian, C. P. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1840-8 · Cited by 168 · see citing works

Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects: a preliminary trial

George, T. P., Chawarski, M. C., Pakes, J., Carroll, K. M., Kosten, T. R., & Schottenfeld, R. S. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00310-8 · Cited by 159 · see citing works

Serum Dopamine-βHydroxylase Activity in the Affective Psychoses and Schizophrenia

Meltzer, H. Y. (1976) · Archives of General Psychiatry · doi:10.1001/archpsyc.1976.01770050047007 · Cited by 144 · see citing works

Dopamine β-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation

Cubells, J. F., van Kammen, D. P., Kelley, M. E., Anderson, G. M., O’Connor, D. T., Price, L. H., Malison, R. T., Rao, P. A., Kobayashi, K., Nagatsu, T., et al. (1998) · Human Genetics · doi:10.1007/s004390050736 · Cited by 134 · see citing works

Dopamine β-Hydroxylase Knockout Mice have Alterations in Dopamine Signaling and are Hypersensitive to Cocaine

Schank, J. R., Ventura, R., Puglisi‐Allegra, S., Alcaro, A., Cole, C. D., Liles, L. C., Seeman, P. M., & Weinshenker, D. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301000 · Cited by 129 · see citing works

Disulfiram Attenuates Drug-Primed Reinstatement of Cocaine Seeking via Inhibition of Dopamine β-Hydroxylase

Schroeder, J. P., Cooper, D. A., Schank, J. R., Lyle, M. A., Gaval‐Cruz, M., Ogbonmwan, Y. E., Pozdeyev, N. V., Freeman, K. G., Iuvone, P. M., Edwards, G. L., et al. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.127 · Cited by 119 · see citing works

Cocaine use and HIV risk behavior in methadone maintenance patients

Bux, D. A., Lamb, R. J., & Iguchi, M. Y. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(94)01058-s · Cited by 115 · see citing works

Disulfiram effects on acute cocaine administration

McCance‐Katz, E. F., Kosten, T. R., & Jatlow, P. L. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00050-7 · Cited by 106 · see citing works

Dopamine agonists for the treatment of cocaine dependence

Minozzi, S., Amato, L., Pani, P. P., Solimini, R., Vecchi, S., Crescenzo, F. D., Zuccaro, P., & Davoli, M. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003352.pub4 · Cited by 105 · see citing works

Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals

Weinshenker, D., Miller, N. S., Blizinsky, K. D., Laughlin, M. L., & Palmiter, R. D. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.212519999 · Cited by 103 · see citing works

Emerging pharmacological strategies in the fight against cocaine addiction

Sofuoglu, M., & Kosten, T. R. (2006) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.11.1.91 · Cited by 100 · see citing works

Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use–dependent inhibitor of dopamine synthesis

Yao, L., Fan, P., Arolfo, M. P., Jiang, Z., Olive, M. F., Zablocki, J. A., Sun, H.-L., Chu, N., Lee, J., Kim, H., et al. (2010) · Nature Medicine · doi:10.1038/nm.2200 · Cited by 99 · see citing works

Genetic control of plasma dopamine- β -hydroxylase

Ross, S. B., Wetterberg, L., & Myrhed, M. (1973) · Life Sciences · doi:10.1016/0024-3205(73)90056-8 · Cited by 99 · see citing works

Effects of dopamine β-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice

Bourdélat-Parks, B. N., Anderson, G. M., Donaldson, Z. R., Weiss, J. M., Bonsall, R. W., Emery, M., Liles, L. C., & Weinshenker, D. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0139-8 · Cited by 97 · see citing works

Catecholamine modulatory effects of nepicastat (RS‐25560‐197), a novel, potent and selective inhibitor of dopamine‐β‐hydroxylase

Stanley, W. C., Li, B., Bonhaus, D. W., Johnson, L. G., Lee, K., Porter, S., Walker, K. A. M., Martinez, G., Eglen, R. M., Whiting, R. L., et al. (1997) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0701315 · Cited by 93 · see citing works

Antecedents and Consequences of Cocaine Abuse among Opioid Addicts

Kosten, T. R., Rounsaville, B. J., & Kleber, H. D. (1988) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198803000-00006 · Cited by 88 · see citing works

The Structure of Linkage Disequilibrium at the DBH Locus Strongly Influences the Magnitude of Association between Diallelic Markers and Plasma Dopamine β-Hydroxylase Activity

Zabetian, C. P., Buxbaum, S. G., Elston, R. C., Köhnke, M. D., Anderson, G. M., Gelernter, J. E., & Cubells, J. F. (2003) · The American Journal of Human Genetics · doi:10.1086/375499 · Cited by 86 · see citing works

HIV infection and cocaine use in methadone maintained and untreated intravenous drug users

Meandzija, B., O’Connor, P. G., Fitzgerald, B. J., Rounsaville, B. J., & Kosten, T. R. (1994) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(94)90092-2 · Cited by 79 · see citing works

Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans

Hameedi, F. A., Rosen, M. I., McCance‐Katz, E. F., McMahon, T. J., Price, L. H., Jatlow, P. I., Woods, S. W., & Kosten, T. R. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00361-6 · Cited by 74 · see citing works

Disulfiram effects on responses to intravenous cocaine administration

Baker, J. R., Jatlow, P. I., & McCance‐Katz, E. F. (2006) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.08.016 · Cited by 73 · see citing works

A genotype-controlled analysis of plasma dopamine β-hydroxylase in healthy and alcoholic subjects: evidence for alcohol-related differences in noradrenergic function

Köhnke, M. D., Zabetian, C. P., Anderson, G., Kolb, W., Gaertner, I., Buchkremer, G., Vonthein, R., Schick, S., Lutz, U. C., Köhnke, A. M., et al. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01427-0 · Cited by 73 · see citing works

Chronic disulfiram treatment effects on intranasal cocaine administration: Initial results

McCance‐Katz, E. F., Kosten, T. R., & Jatlow, P. I. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00506-4 · Cited by 72 · see citing works

Manual-Guided Psychosocial Treatment

Carroll, K. M. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830220041007 · Cited by 70 · see citing works

Disulfiram and Diethyldithiocarbamate Intoxication Affects the Storage and Release of Striatal Dopamine

Vaccari, A., Saba, P., Ruiu, S., Collu, M., & Devoto, P. (1996) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.0147 · Cited by 70 · see citing works

Genotype-controlled analysis of plasma dopamine β-hydroxylase activity in psychotic unipolar major depression

Cubells, J. F., Price, L. H., Meyers, B. S., Anderson, G. M., Zabetian, C. P., Alexopoulos, G. S., Nelson, J. C., Sanacora, G., Kirwin, P. D., Carpenter, L. L., et al. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01349-x · Cited by 61 · see citing works

Possible control of dopamine β-hydroxylase via a codominant mechanism associated with the polymorphic (GT) n repeat at its gene locus in healthy individuals

Wei, J., Ramchand, C. N., & Hemmings, G. P. (1996) · Human Genetics · doi:10.1007/s004390050310 · Cited by 61 · see citing works

Methadone-Related Deaths in Palm Beach County

Wolf, B. C., Lavezzi, W. A., Sullivan, L., & Flannagan, L. M. (2004) · Journal of Forensic Sciences · doi:10.1520/jfs2003221 · Cited by 54 · see citing works

Clinical Characteristics of Emotionally Disturbed Boys with Very Low Activities of Dopamine-β-hydroxylase

Rogeness, G. A., Hernández, J. M., Macedo, C. A., MITCHELL, E. L., AMRUNG, S. A., & Harris, W. R. (1984) · Journal of the American Academy of Child Psychiatry · doi:10.1097/00004583-198403000-00013 · Cited by 54 · see citing works

The long-term outcomes of drug use by methadone maintenance patients

BOVASSO, G. B., & Cacciola, J. (2003) · The Journal of Behavioral Health Services & Research · doi:10.1007/bf02287318 · Cited by 51 · see citing works

Predicting Cocaine Use Among Methadone Patients: Analysis of Findings From a National Study

Dunteman, G. H., Condelli, W. S., & Fairbank, J. A. (1992) · Psychiatric Services · doi:10.1176/ps.43.6.608 · Cited by 50 · see citing works

Near-Zero Plasma Dopamine-β-Hydroxylase and Conduct Disorder in Emotionally Disturbed Boys

Rogeness, G. A., Hernández, J. M., Macedo, C. A., AMRUNG, S. A., & Hoppe, S. K. (1986) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(10)60012-x · Cited by 47 · see citing works

CSF Dopamine β-Hydroxylase in Schizophrenia

Sternberg, D. E. (1983) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790060041005 · Cited by 45 · see citing works

DBH gene variants that cause low plasma dopamine β hydroxylase with or without a severe orthostatic syndrome

Deinum, J., Steenbergen-Spanjers, G. C. H., Jansen, M., Boomsma, F., Lenders, J. W. M., van Ittersum, F. J., Hück, N., van den Heuvel, L. P., & Wevers, R. A. (2004) · Journal of Medical Genetics · doi:10.1136/jmg.2003.009282 · Cited by 44 · see citing works

Monoamine related functional gene variants and relationships to monoamine metabolite concentrations in CSF of healthy volunteers

Jönsson, E. G., Bah, J., Melke, J., Jamra, R. A., Schumacher, J. H., Westberg, L., Ivo, R., Cichon, S., Propping, P., Nöthen, M. M., et al. (2004) · BMC Psychiatry · doi:10.1186/1471-244x-4-4 · Cited by 43 · see citing works

Dopamine agonists for the treatment of cocaine dependence

Amato, L., Minozzi, S., Pani, P. P., Solimini, R., Vecchi, S., Zuccaro, P., & Davoli, M. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003352.pub3 · Cited by 42 · see citing works

CSF dopamine beta-hydroxylase in schizophrenia: associations with premorbid functioning and brain computerized tomography scan measures

van Kammen, D. P., Kelley, M. E., Gilbertson, M. W., Gurklis, J. A., & O'Connor, D. T. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.3.372 · Cited by 42 · see citing works

Changes in HIV Risk Behaviors Among Cocaine-Using Methadone Patients

Magura, S., Rosenblum, A., & Rodriguez, E. M. (1998) · Journal of Addictive Diseases · doi:10.1300/j069v17n04_07 · Cited by 41 · see citing works

Low dopamine-beta-hydroxylase: A biological sequela of abuse and neglect?

Galvin, M. R., Shekhar, A., Simon, J. R., Stilwell, B. M., Eyck, R. L. T., Laite, G., Karwisch, G. A., & Blix, S. (1991) · Psychiatry Research · doi:10.1016/0165-1781(91)90002-7 · Cited by 39 · see citing works

Serum dopamine‐β‐hydroxylase activity in clinical subtypes of depression

Sapru, M. K., Rao, B. S. S., & Channabasavanna, S. M. (1989) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1989.tb03008.x · Cited by 39 · see citing works

The effect of increased cocaine use on drug treatment

Black, J. L., Dolan, M. P., Penk, W. E., Robinowitz, R., & DeFord, H. A. (1987) · Addictive Behaviors · doi:10.1016/0306-4603(87)90042-6 · Cited by 36 · see citing works

Serum DBH activity in psychotic vs. nonpsychotic unipolar and bipolar depression

Mód, L., Rihmer, Z., Magyar, I., Arató, M., Alföldi, A., & Bagdy, G. (1986) · Psychiatry Research · doi:10.1016/0165-1781(86)90127-7 · Cited by 36 · see citing works

Diagnoses, Catecholamine Metabolism, and Plasma Dopamine-β-Hydroxylase

Rogeness, G. A., Maas, J. W., Javors, M. A., Macedo, C. A., Harris, W. R., & Hoppe, S. K. (1988) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-198801000-00019 · Cited by 35 · see citing works

Correlation of Plasma Dopamine β-hydroxylase Activity with Polymorphisms in DBH Gene: A Study on Eastern Indian Population

Bhaduri, N., & Mukhopadhyay, K. (2008) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-007-9256-8 · Cited by 34 · see citing works

Quantitative Fluorescent-PCR Detection of Sex Chromosome Aneuploidies and AZF Deletions/Duplications

Plaseski, T., Noveski, P., Trivodalieva, S., Efremov, G. D., & Plaseska‐Karanfilska, D. (2008) · Genetic Testing · doi:10.1089/gte.2008.0068 · Cited by 33 · see citing works

TREATING COCAINE-USING METHADONE PATIENTS: PREDICTORS OF OUTCOMES IN A PSYCHOSOCIAL CLINICAL TRIAL

Magura, S., Rosenblum, A., Fong, C., Villano, C. L., & Richman, B. L. (2002) · Substance Use & Misuse · doi:10.1081/ja-120016225 · Cited by 33 · see citing works

Plasma dopamine-β-hydroxylase, HVA, MHPG, and conduct disorder in emotionally disturbed boys

Rogeness, G. A., Javors, M. A., Maas, J. W., Macedo, C. A., & Fischer, C. (1987) · Biological Psychiatry · doi:10.1016/0006-3223(87)90058-8 · Cited by 28 · see citing works

The Pharmacogenetics of Major Depression: Past, Present, and Future

Laje, G., & McMahon, F. J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.09.016 · Cited by 26 · see citing works

Factors Associated with Client-Reported HIV Infection Among Clients Entering Methadone Treatment

MacGowan, R. J., Fichtner, R. R., Swanson, N., Collier, C., Kroliczak, A., & Cole, G. E. (1997) · AIDS Education and Prevention · doi:10.1521/aeap.1997.9.3.205 · Cited by 20 · see citing works

TaqI polymorphic sites at the human dopamine β-hydroxylase gene possibly associated with biochemical alterations of the catecholamine pathway in schizophrenia

Wei, J., Ramchand, C. N., & Hemmings, G. P. (1998) · Psychiatric Genetics · doi:10.1097/00041444-199800810-00003 · Cited by 16 · see citing works

Antidepressants for cocaine dependence (Withdrawn Paper. 2010, art no. CD002950)

de Lima, M. S., Farrell, M., Reisser, A. A. L., & Soares, B. G. (2010) · Research Portal (King's College London) · Cited by 16 · see citing works

Possible control of dopamine beta-hydroxylase via a codominant mechanism associated with the polymorphic (GT)n repeat at its gene locus in healthy individuals

Jiang, W., Ramchand, C. N., & Hemmings, G. P. (1997) · Human Molecular Genetics · Cited by 15 · see citing works

Psychotherapeutic Treatment of Cocaine Abuse: Models for Its Evaluation Alone and In Combination With Pharmacotherapy

Carroll, K. M. (1993) · PsycEXTRA Dataset · doi:10.1037/e495932006-009 · Cited by 12 · see citing works

Carbamazepine for cocaine dependence (Withdrawn Paper. 2009, art. no. CD002023)

Reisser, A. A. L., de Lima, M. S., Soares, B. G. D. O., & Farrell, M. (2009) · Research Portal (King's College London) · Cited by 7 · see citing works

Novel Agents for the Pharmacological Treatment of Alcohol Use Disorder

Burnette, E. M., Nieto, S. J., Grodin, E. N., Meredith, L. R., Hurley, B., Miotto, K., Gillis, A. J., & Ray, L. A. (2022) · Drugs · doi:10.1007/s40265-021-01670-3 · Cited by 169 · see citing works

Comparison of Treatments for Cocaine Use Disorder Among Adults: A Systematic Review and Meta-analysis

Bentzley, B. S., Han, S. S., Neuner, S., Humphreys, K., Kampman, K. M., & Halpern, C. H. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.8049 · Cited by 161 · see citing works

Pharmacotherapy for Cocaine Use Disorder—a Systematic Review and Meta-analysis

Chan, B., Kondo, K., Freeman, M., Ayers, C., Montgomery, J., & Kansagara, D. (2019) · Journal of General Internal Medicine · doi:10.1007/s11606-019-05074-8 · Cited by 150 · see citing works

Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism

Lei, Y., Tang, L., Chen, Q., Wu, L., He, W., Tu, D., Wang, S., Chen, Y., Liu, S., Xie, Z., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-34671-1 · Cited by 104 · see citing works

Addiction pharmacogenetics

Patriquin, M. A., Bauer, I. E., Soares, J. C., Graham, D. P., & Nielsen, D. A. (2015) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000095 · Cited by 86 · see citing works

Pharmacotherapeutic strategies for treating cocaine use disorder—what do we have to offer?

Brandt, L., Chao, T. W.-C., Comer, S. D., & LEVIN, F. R. (2020) · Addiction · doi:10.1111/add.15242 · Cited by 85 · see citing works

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

Obeidat, M., Hao, K., Bossé, Y., Nickle, D. C., Nie, Y., Postma, D. S., Laviolette, M., Sandford, A. J., Daley, D., Hogg, J. C., et al. (2015) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(15)00380-x · Cited by 80 · see citing works

The Pharmacogenetics of Alcohol Use Disorder

Jones, J. D., Comer, S. D., & Kranzler, H. R. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12643 · Cited by 79 · see citing works

Psychostimulant addiction treatment

Phillips, K. A., Epstein, D. H., & Preston, K. L. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.04.002 · Cited by 75 · see citing works

Molecular genetics of cocaine use disorders in humans

Noèlia Fernàndez-castillo, A., Cabana‐Domínguez, J., Corominas, R., & Cormand, B. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01256-1 · Cited by 65 · see citing works

Aldehyde dehydrogenase-2 as a therapeutic target

Kimura, M., Yokoyama, A., & Higuchi, S. (2019) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2019.1690454 · Cited by 64 · see citing works

A systematic review and meta-analysis of medications for stimulant use disorders in patients with co-occurring opioid use disorders

Chan, B., Freeman, M., Ayers, C., Korthuis, P. T., Paynter, R., Kondo, K., & Kansagara, D. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108193 · Cited by 56 · see citing works

A Preliminary Study of DBH (Encoding Dopamine Beta-Hydroxylase) Genetic Variation and Neural Correlates of Emotional and Motivational Processing in Individuals With and Without Pathological Gambling

Yang, B., Balodis, I. M., Lacadie, C., Xu, J., & Potenza, M. N. (2016) · Journal of Behavioral Addictions · doi:10.1556/2006.5.2016.026 · Cited by 59 · see citing works

Emerging drugs for the treatment of cocaine use disorder: a review of neurobiological targets and pharmacotherapy

Shorter, D. I., Domingo, C. B., & Kosten, T. R. (2014) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.2015.985203 · Cited by 58 · see citing works

Clinical potential of methylphenidate in the treatment of cocaine addiction: a review of the current evidence

Dürsteler, K. M., Berger, E.-M., Strasser, H., Caflisch, C., Mutschler, J., Herdener, M., & Vogel, M. (2015) · Substance Abuse and Rehabilitation · doi:10.2147/sar.s50807 · Cited by 51 · see citing works

Treatment-refractory substance use disorder: focus on alcohol, opioids, and cocaine

Soyka, M., & Mutschler, J. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.11.003 · Cited by 49 · see citing works

Efficacy of Medications Approved for the Treatment of Alcohol Dependence and Alcohol Withdrawal Syndrome in Female Patients: A Descriptive Review

Agabio, R., Pani, P. P., Preti, A., Gessa, G. L., & Franconi, F. (2015) · European Addiction Research · doi:10.1159/000433579 · Cited by 45 · see citing works

Variation within the serotonin (5-HT) 5-HT2C receptor system aligns with vulnerability to cocaine cue reactivity

Anastasio, N. C., Liu, S., Maili, L., Swinford-Jackson, S. E., Lane, S. D., Fox, R. G., Hamon, S., Nielsen, D. A., Cunningham, K. A., & Moeller, F. G. (2014) · Translational Psychiatry · doi:10.1038/tp.2013.131 · Cited by 42 · see citing works

Pharmacogenetics of naltrexone and disulfiram in alcohol dependent, dually diagnosed veterans

Arias, A. J., Gelernter, J. E., Gueorguieva, R. V., Ralevski, E., & Petrakis, I. L. (2014) · American Journal on Addictions · doi:10.1111/j.1521-0391.2014.12102.x · Cited by 37 · see citing works

DBH gene as predictor of response in a cocaine vaccine clinical trial

Kosten, T. R., Domingo, C. B., Hamon, S., & Nielsen, D. A. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.02.037 · Cited by 35 · see citing works

Biomarkers for the Development of New Medications for Cocaine Dependence

Bough, K. J., Amur, S., Lao, G., Hemby, S., Tannu, N. S., Kampman, K., Schmitz, J., Martinez, D. M., Merchant, K. M., Green, C., et al. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2013.210 · Cited by 37 · see citing works

Psychostimulant use disorder emphasizing methamphetamine and the opioid -dopamine connection: Digging out of a hypodopaminergic ditch

Blum, K., Cadet, J. L., & Gold, M. S. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117252 · Cited by 34 · see citing works

Correlates of cocaine use during methadone treatment: implications for screening and clinical management (ANRS Methaville study)

The ANRS Methaville study group, Roux, P., Lions, C., Vilotitch, A., Michel, L., Mora, M., Maradan, G., Marcellin, F., Spire, B., Morel, A., et al. (2016) · Harm Reduction Journal · doi:10.1186/s12954-016-0100-7 · Cited by 33 · see citing works

Medications to treat cocaine use disorders

Buchholz, J. R., & Saxon, A. J. (2019) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000518 · Cited by 33 · see citing works

ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse

Spellicy, C. J., Kosten, T. R., Hamon, S., Harding, M. J., & Nielsen, D. A. (2013) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e328361c39d · Cited by 32 · see citing works

Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment

Schottenfeld, R. S., Chawarski, M. C., Cubells, J. F., George, T. P., Lappalainen, J., & Kosten, T. R. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.12.007 · Cited by 31 · see citing works

Pharmacogenetics of Addiction Therapy

Nielsen, D. A., Nielsen, E. M., Dasari, T., & Spellicy, C. J. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-0956-8_15 · Cited by 31 · see citing works

A review of pharmacogenetic studies of substance-related disorders

Jones, J. D., & Comer, S. D. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.03.003 · Cited by 31 · see citing works

Pharmacogenetic randomized trial for cocaine abuse: Disulfiram and α1A-adrenoceptor gene variation

Shorter, D. I., Nielsen, D. A., Huang, W., Harding, M. J., Hamon, S., & Kosten, T. R. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.05.014 · Cited by 31 · see citing works

Modifying the role of serotonergic5‐ HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study

Nielsen, D. A., Harding, M. J., Hamon, S., Huang, W., & Kosten, T. R. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00839.x · Cited by 30 · see citing works

Functional neural changes following behavioral therapies and disulfiram for cocaine dependence.

DeVito, E. E., Dong, G., Hedy Kober, A., Xu, J., Carroll, K. M., & Potenza, M. N. (2017) · Psychology of Addictive Behaviors · doi:10.1037/adb0000298 · Cited by 28 · see citing works

The κ-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial

Nielsen, D. A., Hamon, S., & Kosten, T. R. (2013) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000008 · Cited by 27 · see citing works

Selective inhibition of dopamine‐beta‐hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex

Devoto, P., Flore, G., Saba, P., Frau, R., & Gessa, G. L. (2015) · Brain and Behavior · doi:10.1002/brb3.393 · Cited by 27 · see citing works

Pharmacogenetic Role of Dopamine Transporter (SLC6A3) Variation on Response to Disulfiram Treatment for Cocaine Addiction

Kampangkaew, J., Spellicy, C. J., Nielsen, E. M., Harding, M. J., Ye, A., Hamon, S., Kosten, T. R., & Nielsen, D. A. (2019) · American Journal on Addictions · doi:10.1111/ajad.12891 · Cited by 26 · see citing works

Vulnerability to addiction

Maldonado, R. J., Calvé, P., García‐Blanco, A., Domingo‐Rodriguez, L., Senabre, E., & Martín‐García, E. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108466 · Cited by 28 · see citing works

Pharmacotherapy treatment of stimulant use disorder

Liu, M. T. (2021) · Mental Health Clinician · doi:10.9740/mhc.2021.11.347 · Cited by 26 · see citing works

Regulatory Polymorphisms in HumanDBHAffect Peripheral Gene Expression and Sympathetic Activity

Barrie, E. S., Weinshenker, D., Verma, A., Pendergrass, S. A., Lange, L. A., Ritchie, M. D., WILSON, J. G., Kuivaniemi, H., Tromp, G. C., Carey, D. J., et al. (2014) · Circulation Research · doi:10.1161/circresaha.116.304398 · Cited by 26 · see citing works

Human pharmacology for addiction medicine

Quednow, B. B., & Herdener, M. (2015) · Progress in brain research · doi:10.1016/bs.pbr.2015.07.017 · Cited by 25 · see citing works

Evaluating the Impact of Naltrexone on the Rat Gambling Task to Test Its Predictive Validity for Gambling Disorder

Ciano, P. D., & Foll, B. L. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155604 · Cited by 18 · see citing works

The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics

Zhang, S., Zong, Y., Chen, L., Li, Q., Li, Z., & Meng, R. (2023) · Discover Oncology · doi:10.1007/s12672-023-00729-9 · Cited by 23 · see citing works

Evaluation of the dopamine β-hydroxylase (DβH) inhibitor nepicastat in participants who meet criteria for cocaine use disorder

Garza, R. D. L., Bubar, M. J., Carbone, C. L., Moeller, F. G., Newton, T. F., Anastasio, N. C., Harper, T. A., Ware, D. L., Fuller, M. A., Holstein, G. J., et al. (2015) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.01.009 · Cited by 22 · see citing works

Pharmacogenetics ofDopamine β‐Hydroxylasein cocaine dependence therapy with doxazosin

Zhang, X., Nielsen, D. A., Domingo, C. B., Shorter, D. I., Nielsen, E. M., & Kosten, T. R. (2018) · Addiction Biology · doi:10.1111/adb.12611 · Cited by 21 · see citing works

Combined effect of common gene variants on response to drug withdrawal therapy in medication overuse headache

Cargnin, S., Viana, M., Sances, G., Bianchi, M., Ghiotto, N., Tassorelli, C., Nappi, G., Canonico, P. L., Genazzani, A. A., & Terrazzino, S. (2014) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-014-1726-6 · Cited by 20 · see citing works

Disulfiram for binge eating disorder: An open trail

Farci, A. M. G., Piras, S., Murgia, M., Chessa, A., Restivo, A., Gessa, G. L., & Agabio, R. (2014) · Eating Behaviors · doi:10.1016/j.eatbeh.2014.10.008 · Cited by 20 · see citing works

The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency

Spellicy, C. J., Kosten, T. R., Hamon, S., Harding, M. J., & Nielsen, D. A. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00109 · Cited by 19 · see citing works

Genetic variation of the dopamine transporter (DAT1) influences the acute subjective responses to cocaine in volunteers with cocaine use disorders

Brewer, A. J., Nielsen, D. A., Spellicy, C. J., Hamon, S., Gingrich, J., Thompson-Lake, D. G. Y., Nielsen, E. M., Mahoney, J. J., Kosten, T. R., Newton, T. F., et al. (2015) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0000000000000137 · Cited by 19 · see citing works

The influence of dopamine β-hydroxylase gene polymorphism rs1611115 on levodopa/carbidopa treatment for cocaine dependence

Liu, S., Green, C. E., Lane, S. D., Kosten, T. R., Moeller, F. G., Nielsen, D. A., & Schmitz, J. M. (2014) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0000000000000055 · Cited by 18 · see citing works

Effects of Pharmacologic Dopamine β-Hydroxylase Inhibition on Cocaine-Induced Reinstatement and Dopamine Neurochemistry in Squirrel Monkeys

Cooper, D. A., Kimmel, H. L., Manvich, D. F., Schmidt, K. T., Weinshenker, D., & Howell, L. L. (2014) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.113.212357 · Cited by 18 · see citing works

A variant in ANKK1 modulates acute subjective effects of cocaine: a preliminary study

Spellicy, C. J., Harding, M. J., Hamon, S., Mahoney, J. J., Reyes, J. A., Kosten, T. R., Newton, T. F., Garza, R. D. L., & Nielsen, D. A. (2014) · Genes Brain & Behavior · doi:10.1111/gbb.12121 · Cited by 17 · see citing works

Why haven't we solved the addiction crisis?

Blum, K., Bowirrat, A., Llanos-Gomez, L., Downs, B. W., Bagchi, D., Barh, D., Modestino, E. J., Baron, D. A., McLaughlin, T., Thanos, P. K., et al. (2022) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2022.120404 · Cited by 18 · see citing works

Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels

Ciano, P. D., Manvich, D. F., Pushparaj, A., Gappasov, A., Hess, E., Weinshenker, D., & Foll, B. L. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4744-0 · Cited by 16 · see citing works

Apolipoprotein E DNA methylation and posttraumatic stress disorder are associated with plasma ApoE level: A preliminary study

Nielsen, D. A., Spellicy, C. J., Harding, M. J., & Graham, D. P. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.05.013 · Cited by 17 · see citing works

Integrative Pharmacology in the Treatment of Substance Use Disorders

Donlon, J., Kumari, P., Varghese, S. P., Bai, M. Y., Florentin, O. D., Frost, E. D., Banks, J., Vadlapatla, N., Kam, O., Shad, M. U., et al. (2023) · Journal of Dual Diagnosis · doi:10.1080/15504263.2023.2293854 · Cited by 15 · see citing works

Doxazosin treatment in cocaine use disorder: pharmacogenetic response based on an alpha-1 adrenoreceptor subtype D genetic variant

Shorter, D. I., Zhang, X., Domingo, C. B., Nielsen, E. M., Kosten, T. R., & Nielsen, D. A. (2020) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2019.1674864 · Cited by 15 · see citing works

Integrative Bayesian analysis of neuroimaging-genetic data with application to cocaine dependence

Azadeh, S., Hobbs, B. P., Ma, L., Nielsen, D. A., Gerard Moeller, F., & Baladandayuthapani, V. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2015.10.033 · Cited by 12 · see citing works

Pharmacogenomic and Pharmacomicrobiomic Aspects of Drugs of Abuse

Borrego-Ruiz, A., & Borrego, J. J. (2025) · Genes · doi:10.3390/genes16040403 · Cited by 15 · see citing works

Dopamine β-Hydroxylase Inhibitors Enhance the Discriminative Stimulus Effects of Cocaine in Rats

Manvich, D. F., DePoy, L. M., & Weinshenker, D. (2013) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.113.207746 · Cited by 14 · see citing works

FAAH variant Pro129Thr modulates subjective effects produced by cocaine administration

Patel, M. M., Nielsen, D. A., Kosten, T. R., Garza, R. D. L., Newton, T. F., & Verrico, C. D. (2018) · American Journal on Addictions · doi:10.1111/ajad.12788 · Cited by 14 · see citing works

Pharmacotherapy for Stimulant-Related Disorders

Haile, C. N., & Kosten, T. R. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-013-0415-y · Cited by 13 · see citing works

A mechanistic overview of approaches for the treatment of psychostimulant dependence

Jensen, K. L., Jensen, S. B., & Madsen, K. L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.854176 · Cited by 12 · see citing works

Disulfiram for the treatment of cocaine dependence

Traccis, F., Minozzi, S., Trogu, E., Vacca, R., Vecchi, S., Pani, P. P., & Agabio, R. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007024.pub3 · Cited by 11 · see citing works

Comparison of Caffeine and d-amphetamine in Cocaine-Dependent Subjects: Differential Outcomes on Subjective and Cardiovascular Effects, Reward Learning, and Salivary Paraxanthine

Lane, S. D. (2014) · Journal of Addiction Research & Therapy · doi:10.4172/2155-6105.1000176 · Cited by 11 · see citing works

Psychotic Symptoms Associated with the use of Dopaminergic Drugs, in Patients with Cocaine Dependence or Abuse

Roncero, C., Abad, A. C., Padilla-Mata, A., Ros‐Cucurull, E., Barral, C., Casas, M., & Grau‐López, L. (2016) · Current Neuropharmacology · doi:10.2174/1570159x14666160324144912 · Cited by 9 · see citing works

GABAergic polygenic risk for cocaine use disorder is negatively correlated with precuneus activity during cognitive control in African American individuals

Yang, B., Balodis, I. M., Hedy Kober, A., Worhunsky, P. D., Lacadie, C., Gelernter, J. E., & Potenza, M. N. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2020.106695 · Cited by 7 · see citing works

Developing Treatments for Stimulant Abuse: A Brief Overview.

Davidson, C. (2016) · PubMed · Cited by 7 · see citing works

Toxicology in Addiction Medicine

Schwarz, D. A., George, M. P., & Bluth, M. H. (2016) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2016.07.009 · Cited by 7 · see citing works

Association of dopamine β-hydroxylase polymorphism rs1611115 and serum levels with psychiatric disorders in Pakistani population

Hashmi, A. N., Dharejo, R. A., Zubair, U. B., Khan, N., Kashif, I., Ajmal, M., Taj, R., Qamar, R., & Azam, M. (2022) · International Journal of Neuroscience · doi:10.1080/00207454.2022.2126774 · Cited by 6 · see citing works

Treatment with dopamine β-hydroxylase (DBH) inhibitors prevents morphine use and relapse-like behavior in rats

Frankowska, M., Surówka, P., Suder, A., Pieniążek, R., Pukło, R., Jastrzębska, J., Daniel, W. A., Filip, M., Bujalska-Zadrożny, M., & Kleczkowska, P. (2021) · Pharmacological Reports · doi:10.1007/s43440-021-00307-2 · Cited by 6 · see citing works

Disulfiram: Pharmacology and Mechanism of Action

Sousa, A. D. (2019) · Springer eBooks · doi:10.1007/978-981-32-9876-7_2 · Cited by 6 · see citing works

Association between a functional polymorphism on the dopamine-β-hydroxylase gene and reward dependence in two independent samples

Plieger, T., Felten, A., Melchers, M., Markett, S. A., Montag, C., & Reuter, M. (2017) · Personality and Individual Differences · doi:10.1016/j.paid.2017.05.050 · Cited by 6 · see citing works

Rivastigmine does not alter cocaine-induced subjective effects or self-administration

Patel, M. M., Verrico, C. D., & Garza, R. D. L. (2019) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2019.172758 · Cited by 5 · see citing works

Pharmacogenetics of Addiction Therapy

Graham, D. P., Harding, M. J., & Nielsen, D. A. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2573-6_16 · Cited by 6 · see citing works

Identification of key genes and therapeutic drugs for cocaine addiction using integrated bioinformatics analysis

Wang, X., Sun, S., Chen, H., Yun, B., Zhang, Z., Wang, X., Wu, Y., Lv, J., He, Y., Wan, L., et al. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1201897 · Cited by 5 · see citing works

The α-1 adrenoceptor (ADRA1A) genotype moderates the magnitude of acute cocaine-induced subjective effects in cocaine-dependent individuals

Shorter, D. I., Nielsen, D. A., Hamon, S., Nielsen, E. M., Kosten, T. R., Newton, T. F., & Garza, R. D. L. (2016) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0000000000000234 · Cited by 5 · see citing works

The OPRD1 rs678849 variant influences outcome of disulfiram treatment for cocaine dependency in methadone-maintained patients

Thomas, P. S., Nielsen, E. M., Spellicy, C. J., Harding, M. J., Ye, A., Patriquin, M. A., Hamon, S., Kosten, T. R., & Nielsen, D. A. (2021) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000279 · Cited by 5 · see citing works

PharmGKB summary: disulfiram pathway

Gonzalez-Suarez, A. D., Thorn, C. F., Whirl‐Carrillo, M., & Klein, T. E. (2023) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0000000000000509 · Cited by 4 · see citing works

Regaining control over alcohol intake but not abstinence on disulfiram medication, as a harm reduction approach: 2 case reports

Schallenberg, M., Pilhatsch, M., Petzold, J., Vogel, D., Zimmermann, U. S., & Spreer, M. (2024) · Addiction Science & Clinical Practice · doi:10.1186/s13722-024-00522-1 · Cited by 4 · see citing works

Treatment of Cocaine Addiction

Gorelick, D. A. (2014) · Springer eBooks · doi:10.1007/978-88-470-5322-9_15 · Cited by 4 · see citing works

Serotonin transporter gene promoter polymorphism predicts relationship between years of cocaine use and impulsivity

Liu, S., Maili, L., Lane, S. D., Schmitz, J. M., Spellicy, C. J., Cunningham, K. A., Moeller, F. G., & Nielsen, D. A. (2015) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000094 · Cited by 4 · see citing works

The role of polysubstance use in the development, maintenance, and treatment of stimulant use disorders

Rough, M. I., & Nader, M. A. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100119 · Cited by 3 · see citing works

The Role of Norepinephrine in Drug Addiction: Past, Present, and Future

Foster, S. L., & Weinshenker, D. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812202-0.00015-4 · Cited by 3 · see citing works

Disulfiram in the Management of Cocaine Dependence and Other Psychiatric Disorders

Sousa, A. D. (2019) · Springer eBooks · doi:10.1007/978-981-32-9876-7_4 · Cited by 3 · see citing works

Disulfiram in the Management of Alcohol Dependence

Sousa, A. D. (2019) · Springer eBooks · doi:10.1007/978-981-32-9876-7_3 · Cited by 2 · see citing works

Cocaine Addiction and Treatment

Gorelick, D. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-36391-8_13 · Cited by 2 · see citing works

Disorders due to Substance Use: Stimulants

Sevarino, K. A., & Farrell, M. (2024) · Springer eBooks · doi:10.1007/978-3-030-51366-5_26 · Cited by 3 · see citing works

Dopamine Beta Hydroxylase: An Enzyme with Therapeutic Potential to Combat Neural and Cardiovascular Diseases

Kundu, S., Saini, M., Dey, S. K., & Kundu, S. (2020) · Springer eBooks · doi:10.1007/978-981-15-5530-5_14 · Cited by 2 · see citing works

Off-label and repurposed use of disulfiram beyond alcohol dependence: A systematic review of clinical and preclinical evidence

Benkő, B.-M., De Brito Parreirinha, N. S., Sebe, I., & Zelkó, R. (2026) · iScience · doi:10.1016/j.isci.2026.115441 · Cited by 2 · see citing works

Caracterización del gen de la dopamina (β-hidroxilasa en población mestiza colombiana

Mejía, C. A. I., Bonilla, J. H., Valencia-Castillo, S., Beltrán, L., & Calvo, A. M. (2013) · Areandina · doi:10.33132/01248146.31 · Cited by 1 · see citing works

Pharmacogenetics of naltrexone and disulfiram in alcohol dependent, dually diagnosed veterans

Arias, A. J., Gelernter, J. E., Gueorguieva, R. V., Ralevski, E., & Petrakis, I. L. (2013) · American Journal on Addictions · doi:10.1111/j.1521-0391.2013.12102.x · Cited by 1 · see citing works

Genetic Factors Underlying Treatment Resistance in Psychiatry

Maron, E., Lan, C., & Nutt, D. (2018) · Springer eBooks · doi:10.1007/978-981-10-4358-1_3 · Cited by 2 · see citing works

Substanzbezogene Störungen

Claus, A., Gerlach, M., Stohler, R., & Wiesbeck, G. A. (2016) · Springer eBooks · doi:10.1007/978-3-662-48624-5_25 · Cited by 1 · see citing works

Using Genetics to Improve Addiction Treatment Outcomes

Allenby, C. E., & Falcone, M. (2017) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-017-0106-9 · Cited by 1 · see citing works

A rodent model of phenotypic variation in sweet preference, addiction vulnerability, and pharmacological treatment sensitivity

Holtz, N. A. (2013) · University of Minnesota Digital Conservancy (University of Minnesota)

Offenders with mental health problems and problematic substance use : treatment interventions and crime relapse

Durbeej, N. (2014) · Figshare

The Specific Binding between Aptamer and its Target Molecules Investigated by Microcantilever Sensor

Zhang, H. Y. (2013) · Advanced materials research · doi:10.4028/www.scientific.net/amr.811.455

Correlación genotipo-fenotipo cardiovascular de la dopamina β-hidroxilasa (DβH)

Mejia, C. A. I., C, S. Y. V., G, C. M. R., Andrea López, B., Beatriz Giraldo, O., & Alejandra Quiceno, G. (2015) · Revista Médica de Risaralda · doi:10.22517/25395203.11461

The Influence of Dopamine Beta-Hydroxylase Gene Polymorphism C.-979T>C (Rs1611115) on the Clinical Manifestations of Migraine

Климов, Е. А. (2018) · Journal of Neurology & Stroke · doi:10.15406/jnsk.2018.08.00276

Bibliography: Substance-Related and Addictive Disorders

(2015) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.130311

PRACTICE TESTS ANSWER KEY (CHAPTER 14)

(2022) · Elsevier eBooks · doi:10.1016/b978-0-323-75486-6.00025-4

Pathophysiology, Molecular Interaction Mechanism, Metabolism, Pharmacotherapy and New Perspectives in the Pharmacological Treatment of Chemical Dependence on the Main Illicit Drugs Consumed in the World

Ferreira, J. V., Chaves, G. A., Batista, M. A., Correia, L. C., de Souza, L. R., da Costa, D. C., Barcelos, M. P., da Silva, C. H. T. D. P., Taft, C. A., & Hage-Melim, L. I. D. S. (2022) · Engineering materials · doi:10.1007/978-3-031-07622-0_16

Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment

Schottenfeld, R. S., Chawarski, M. C., Cubells, J. F., George, T. P., Lappalainen, J., & Kosten, T. R. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.12.007 · Cited by 31 · see citing works

Pharmacogenetic randomized trial for cocaine abuse: Disulfiram and α1A-adrenoceptor gene variation

Shorter, D. I., Nielsen, D. A., Huang, W., Harding, M. J., Hamon, S., & Kosten, T. R. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.05.014 · Cited by 31 · see citing works

Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures

Gaval‐Cruz, M., Schroeder, J. P., Liles, L. C., Javors, M. A., & Weinshenker, D. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.02.009 · Cited by 24 · see citing works

Pharmacogenetic Role of Dopamine Transporter (SLC6A3) Variation on Response to Disulfiram Treatment for Cocaine Addiction

Kampangkaew, J., Spellicy, C. J., Nielsen, E. M., Harding, M. J., Ye, A., Hamon, S., Kosten, T. R., & Nielsen, D. A. (2019) · American Journal on Addictions · doi:10.1111/ajad.12891 · Cited by 26 · see citing works

ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse

Spellicy, C. J., Kosten, T. R., Hamon, S., Harding, M. J., & Nielsen, D. A. (2013) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e328361c39d · Cited by 32 · see citing works