Aberrant disgust responses and immune reactivity in cocaine-dependent men.
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Cocaine is associated with increased immune reactivity and inflammation in humans and neuroinflammation in animal models.
“Cocaine is a highly potent and addictive brain stimulant that is associated with increased immune reactivity and inflammation in humans (Fox et al., 2012; Ersche et al., 2014; Levandowski et al., 2016; Moreira et al., 2016; Pianca et al., 2017) and neuroinflammation in animal models (Guo et al., 2015; Periyasamy et al., 2017).”
From Engineered Extracellular Vesicles Loaded With miR-124 Attenuate Cocaine-Mediated Activation of Microglia (2020) · cites this paper as Ersche et al., 2014
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Autonomic nervous system activity in emotion: a review
Kreibig, S. D. (2010) · Biological Psychology · doi:10.1016/j.biopsycho.2010.03.010 · Cited by 3,188 · see citing works
Steptoe, A., Hamer, M., & Chida, Y. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.03.011 · Cited by 1,278 · see citing works
Autonomic innervation and regulation of the immune system (1987–2007)
Nance, D. M., & Sanders, V. M. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.03.008 · Cited by 855 · see citing works
Disgust: evolved function and structure
Tybur, J. M., Lieberman, D., Kurzban, R., & DeScioli, P. (2013) · Psychological Review · doi:10.1037/a0030778 · Cited by 810 · see citing works
The insula and drug addiction: an interoceptive view of pleasure, urges, and decision-making
Naqvi, N. H., & Bechara, A. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0268-7 · Cited by 598 · see citing works
Can the emotion of disgust be harnessed to promote hand hygiene? Experimental and field-based tests
Porzig-Drummond, R., Stevenson, R., Case, T., & Oaten, M. (2009) · Social Science & Medicine · doi:10.1016/j.socscimed.2009.01.013 · Cited by 122 · see citing works
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Research works printed but not linked: 73
- [1]DeBeck K. Kerr T. Li K. Fischer B. Buxton J. Montaner J. Smoking of crack cocaine as a risk factor for HIV infection among people who use injection drugs Can Med Assoc J 181 2009 585 589 19841052 PMC2764753
- [2]Garfein R.S. Vlahov D. Galai N. Doherty M.C. Nelson K.E. Viral infections in short-term injection drug users: The prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses Am J Public Health 86 1996 655 661 8629715 PMC1380472
- [3]Gordon R.J. Lowy F.D. Bacterial infections in drug users N Engl J Med 353 2005 1945 1954 16267325
- [4]Story A. Bothamley G. Hayward A. Crack cocaine and infectious tuberculosis Emerg Infect Dis 14 2008 1466 1469 18760022 PMC2603115
- [5]Wilson T. DeHovitz J.A. STDs, HIV, and crack cocaine: A review Aids Patient Care STDS 11 1997 62 66 11361764
- [8]Fischer B. Powis J. Cruz M.F. Rudzinski K. Rehm J. Hepatitis C virus transmission among oral crack users: Viral detection on crack paraphernalia Eur J Gastroent Hepat 20 2008 29 32 18090987
- [9]Scheinmann R. Hagan H. Lelutiu-Weinberger C. Stern R. Jarlais D.C.D. Flom P.L. Non-injection drug use and Hepatitis C Virus: A systematic review Drug Alcohol Depen 89 2007 1 12 PMC1892753 17174481
- [10]Howe C.J. Fuller C.M. Ompad D.C. Galea S. Koblin B. Thomas D. Association of sex, hygiene and drug equipment sharing with hepatitis C virus infection among non-injecting drug users in New York City Drug Alcohol Depen 79 2005 389 395 16102381
- [11]Khan M.R. Berger A. Hemberg J. O’Neill A. Dyer T.P. Smyrk K. Non-injection and injection drug use and STI/HIV risk in the United States: The degree to which sexual risk behaviors versus sex with an STI-infected partner account for infection transmission among drug users AIDS Behav 17 2013 1185 1194 22890684 PMC3923515
- [12]Roy K. Howie H. Sweeney C. Parry J. Molyneaux P. Goldberg D. Hepatitis A virus and injecting drug misuse in Aberdeen, Scotland: A case–control study J Viral Hepat 11 2004 277 282 15117332
- [13]Gyarmathy V.A. Neaigus A. Miller M. Friedman S.R. Des Jarlais D.C. Risk correlates of prevalent HIV, hepatitis B virus, and hepatitis C virus infections among noninjecting heroin users J Acq Immun Def Synd 30 2002 448 456 12138352
- [14]Clark K.H. Wiley C.A. Bradberry C.W. Psychostimulant abuse and neuroinflammation: Emerging evidence of their interconnection Neurotox Res 23 2013 174 188 22714667
- [15]Friedman H. Pross S. Klein T.W. Addictive drugs and their relationship with infectious diseases FEMS Immunol Med Mic 47 2006 330 342 16872369
- [16]Reece A.S. Clinical implications of addiction related immunosuppression J Infection 56 2008 437 445 18440646
- [17]Stefanidou M. Loutsidou A.C. Chasapis C.T. Spiliopoulou C.A. Immunotoxicity of Cocaine and Crack Curr Drug Abuse Rev 4 2011 95 97 21696343
- [18]Baldwin G.C. Roth M.D. Tashkin D.P. Acute and chronic effects of cocaine on the immune system and the possible link to AIDS J Neuroimmunol 83 1998 133 138 9610681
- [19]Pellegrino T. Bayer B.M. In vivo effects of cocaine on immune cell function J Neuroimmunol 83 1998 139 147 9610682
- [20]Halpern J.H. Sholar M.B. Glowacki J. Mello N.K. Mendelson J.H. Siegel A.J. Diminished interleukin-6 response to proinflammatory challenge in men and women after intravenous cocaine administration J Clin Endocrinol Metab 88 2003 1188 1193 12629105
- [21]Irwin M.R. Olmos L. Wang M. Valladares E.M. Motivala S.J. Fong T. Cocaine dependence and acute cocaine induce decreases of monocyte proinflammatory cytokine expression across the diurnal period: Autonomic mechanisms J Pharmacol Exp Ther 320 2007 507 515 17068203
- [22]Chen Y. Ke Q. Xiao Y.F. Wu G. Kaplan E. Hampton T.G. Cocaine and catecholamines enhance inflammatory cell retention in the coronary circulation of mice by upregulation of adhesion molecules Am J Physiol Heart Circ Physiol 288 2005 2323 2331 15637118
- [23]Meng Q. Lima J.A. Lai H. Vlahov D. Celentano D.D. Margolick J.B. Elevated C-reactive protein levels are associated with endothelial dysfunction in chronic cocaine users Int J Cardiol 88 2003 191 198 12714198
- [24]Siegel A.J. Mendelson J.H. Sholar M.B. McDonald J.C. Lewandrowski K.B. Lewandrowski E.L. Effect of cocaine usage on C-reactive protein, von Willebrand factor, and fibrinogen Am J Cardiol 89 2002 1133 1135 11988210
- [25]Pacheco-Lopez G. Bermudez-Rattoni F. Brain–immune interactions and the neural basis of disease-avoidant ingestive behaviour Philos Trans R Soc Lond B 366 2011 3389 3405 22042916 PMC3189354
- [26]Riether C. Doenlen R. Pacheco-Lopez G. Niemi M.B. Engler A. Engler H. Behavioural conditioning of immune functions: How the central nervous system controls peripheral immune responses by evoking associative learning processes Rev Neuroscience 19 2008 1 17 18561817
- [27]Stevenson R.J. Case T.I. Oaten M.J. Proactive strategies to avoid infectious disease Philos Trans R Soc Lond B 366 2011 3361 3363 22042913 PMC3189360
- [28]Oaten M. Stevenson R.J. Case T.I. Disgust as a disease-avoidance mechanism Psychol Bull 135 2009 303 321 19254082
- [29]Curtis V. de Barra M. Aunger R. Disgust as an adaptive system for disease avoidance behaviour Philos Trans R Soc Lond B 366 2011 389 401 21199843 PMC3013466
- [30]Rozin P. Fallon A.E. A perspective on disgust Psychol Rev 94 1987 23 41 3823304
- [33]Ader R. Cohen N. Behaviorally conditioned immunosuppression and murine systemic lupus erythematosus Science 215 1982 1534 1536 7063864
- [34]Schedlowski M. Pacheco-Lopez G. The learned immune response: Pavlov and beyond Brain Behav Immun 24 2010 176 185 19698779
- [35]Schaller M. Miller G.E. Gervais W.M. Yager S. Chen E. Mere visual perception of other people’s disease symptoms facilitates a more aggressive immune response Psychol Sci 21 2010 649 652 20483842
- [36]Baumann H. Gauldie J. The acute phase response Immunol Today 15 1994 74 80 7512342
- [37]Gabay C. Kushner I. Acute-phase proteins and other systemic responses to inflammation N Engl J Med 340 1999 448 454 9971870
- [38]Butcher E.C. Williams M. Youngman K. Rott L. Briskin M. Lymphocyte trafficking and regional immunity Frank J.D. Advances in Immunology Vol 72 1999 Academic Press San Diego, CA 209 253 10361577
- [40]Sheehan D.V. Lecrubier Y. Sheehan K.H. Amorim P. Janavs J. Weiller E. The Mini-International Neuropsychiatric Interview (MINI): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 J Clin Psychiatry 59 1998 22 33 9881538
- [41]First M.B. Spitzer R.L. Gibbon M. Williams J.B.W. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition. (SCID-I/NP) 2002 Biometrics Research, New York State Psychiatric Institute New York
- [42]Lovibond P.F. Lovibond S.H. The structure of negative emotional states: Comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories Behav Res Ther 33 1995 335 343 7726811
- [44]Ersche K.D. Stochl J. Woodward J.M. Fletcher P.C. The skinny on cocaine. Insights into eating behavior and body weight in cocaine-dependent men Appetite 71 2013 75 80 23920064 PMC3863945
- [45]Preston K.L. Epstein D.H. Cone E.J. Wtsadik A.T. Huestis M.A. Moolchan E.T. Urinary elimination of cocaine metabolites in chronic cocaine users during cessation J Anal Toxicol 26 2002 393 400 12422991
- [46]Fuse S. Molloy M.J. Usherwood E.J. Immune responses against persistent viral infections: Possible avenues for immunotherapeutic interventions Crit Rev Immunol 28 2008 159 183 18540829
- [47]Black S. Kushner I. Samols D. C-reactive Protein J Biol Chem 279 2004 48487 48490 15337754
- [48]Stevenson R.J. Hodgson D. Oaten M.J. Barouei J. Case T.I. The effect of disgust on oral immune function Psychophysiology 48 2011 900 907 21166686
- [49]Stevenson R.J. Hodgson D. Oaten M.J. Moussavi M. Langberg R. Case T.I. Disgust elevates core body temperature and up-regulates certain oral immune markers Brain Behav Immun 26 2012 1160 1168 22841694
- [50]Szabo S.J. Sullivan B.M. Peng S.L. Glimcher L.H. Molecular mechanisms regulating Th1 immune responses Annual Review of Immunology 21 2003 713 758 12500979
- [51]Kobayashi Y. The role of chemokines in neutrophil biology Front Biosci Landmark 13 2008 2400 2407 17981721
- [53]Stevenson R.J. Case T.I. Hodgson D. Porzig-Drummond R. Barouei J. Oaten M.J. A scale for measuring hygiene behavior: Development, reliability and validity Am J Infect Control 37 2009 557 564 19362392
- [55]Stanislaw H. Todorov N. Calculation of signal detection theory measures Behav Res Meth Instr 31 1999 137 149 10495845
- [56]Howell D.C. Statistical Methods for Psychology 4th ed. 1997 Duxbury Press London
- [57]Ansar W. Ghosh S. C-reactive protein and the biology of disease Immunol Res 56 2013 131 142 23371836
- [58]Hou R. Baldwin D.S. A neuroimmunological perspective on anxiety disorders Hum Psychopharmacol Clin Exp 27 2012 6 14 22213434
- [60]Miller G.A. Chapman J.P. Misunderstanding analysis of covariance J Abnorm Psychol 110 2001 40 48 11261398
- [61]Critchley H.D. Electrodermal responses: What happens in the brain Neuroscientist 8 2002 132 142 11954558
- [62]Erta M. Quintana A. Hidalgo J. Interleukin-6, a major cytokine in the central nervous system Int J Biol Sci 8 2012 1254 1266 23136554 PMC3491449
- [63]Lekander M. Furst C.J. Rotstein S. Blomgren H. Fredrikson M. Anticipatory immune changes in women treated with chemotherapy for ovarian-cancer Int J Behav Med 2 1995 1 12 16250785
- [65]Stockhorst U. Spennes-Saleh S. Körholz D. Göbel U. Schneider M.E. Steingrüber H.J. Anticipatory symptoms and anticipatory immune responses in pediatric cancer patients receiving chemotherapy: Features of a classically conditioned response? Brain Behav Immun 14 2000 198 218 10970680
- [66]Aps J.K.M. Martens L.C. Review: The physiology of saliva and transfer of drugs into saliva Forensic Sci Int 150 2005 119 131 15944052
- [67]Gornikiewicz A. Sautner T. Brostjan C. Schmierer B. Fugger R. Roth E. Catecholamines up-regulate lipopolysaccharide-induced IL-6 production in human microvascular endothelial cells FASEB J 14 2000 1093 1100 10834930
- [68]Marz P. Cheng J.G. Gadient R.A. Patterson P.H. Stoyan T. Otten U. Sympathetic neurons can produce and respond to interleukin 6 PNAS 95 1998 3251 3256 9501249 PMC19728
- [69]Lang P.J. Greenwald M.K. Bradley M.M. Hamm A.O. Looking at Pictures—Affective, facial, visceral, and behavioral reactions Psychophysiology 30 1993 261 273 8497555
- [71]Jacobsen T.N. Grayburn P.A. Snyder R.W. Hansen J. Chavoshan B. Landau C. Effects of intranasal cocaine on sympathetic nerve discharge in humans J Clin Invest 99 1997 628 634 9045864 PMC507844
- [72]Vongpatanasin W. Mansour Y. Chavoshan B. Arbique D. Victor R.G. Cocaine stimulates the human cardiovascular system via a central mechanism of action Circulation 100 1999 497 502 10430763
- [74]Marsland A.L. Bachen E.A. Cohen S. Rabin B. Manuck S.B. Stress, immune reactivity and susceptibility to infectious disease Physiol Behav 77 2002 711 716 12527024
- [75]Bosch J.A. De Geus E.J.C. Veerman E.C.I. Hoogstraten J. Amerongen A.V.N. Innate secretory immunity in response to laboratory stressors that evoke distinct patterns of cardiac autonomic activity Psychosom Med 65 2003 245 258 12651992
- [76]Reichenberg A. Kraus T. Haack M. Schuld A. Pollmächer T. Yirmiya R. Endotoxin-induced changes in food consumption in healthy volunteers are associated with TNF-alpha and IL-6 secretion Psychoneuroendocrinology 27 2002 945 956 12383455
- [77]Konsman J.P. Parnet P. Dantzer R. Cytokine-induced sickness behaviour: Mechanisms and implications Trends Neurosci 25 2002 154 159 11852148
- [80]Roncero C. Grau-Lopez L. Diaz-Moran S. Miquel L. Martinez-Luna N. Casas M. Evaluation of sleep disorders in drug dependent inpatients Med Clin 138 2012 332 335 22018396
- [81]Erickson K.L. Medina E.A. Hubbard N.E. Micronutrients and innate immunity J Infect Dis 182 2000 S5 S10 10944478
- [82]Gamaldo C.E. Shaikh A.K. McArthur J.C. The sleep-immunity relationship Neurol Clin 30 2012 1313 1343 23099140
- [83]Paulus M.P. Tapert S.F. Schulteis G. The role of interoception and alliesthesia in addiction Pharmacol Biochem Behav 94 2009 1 7 19698739 PMC2753707
- [85]Goldstein R.Z. Craig A.D. Bechara A. Garavan H. Childress A.R. Paulus M.P. The neurocircuitry of impaired insight in drug addiction Trends Cogn Sci 13 2009 372 380 19716751 PMC2844118
- [86]Verdejo-Garcia A. Clark L. Dunn B.D. The role of interoception in addiction: A critical review Neurosci Biobehav Rev 36 2012 1857 1869 22659642
- [87]Ribeiro L.A. Sanchez Z.M. Nappo S.A. Surviving crack: A qualitative study of the strategies and tactics developed by Brazilian users to deal with the risks associated with the drug BMC Public Health 10 2010 672 21050465 PMC3091576
- [88]Malchy L.A. Bungay V. Johnson J.L. Buxton J. Do crack smoking practices change with the introduction of safer crack kits? Can J Public Health 102 2011 188 192 21714316 PMC6973889
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Cocaine abuse and effects in the serum levels of cytokines IL-6 and IL-10
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Chivero, E. T., Liao, K., Niu, F., Tripathi, A., Tian, C., Buch, S., & Hu, G. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00573 · Cited by 69 · see citing works
Soto-Méndez, M. J., Romero-Abal, M. E., Aguilera, C. M., Rico, M. C., Solomons, N. W., Schümann, K., & Gil, A. (2015) · PLOS ONE · doi:10.1371/journal.pone.0129158 · Cited by 12 · see citing works
- Authors
- Ersche, K. D., Hagan, C. C., Smith, D. G., Abbott, S., Jones, P. S., Apergis-Schoute, A. M., & Döffinger, R.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2014-01
- Volume
- 75
- Issue
- 2
- Pages
- 140-147
- ISSN
- 0006-3223
- PMC
- PMC3898808
- Cited by
- 45
- References
- 6
- Language
- en
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