The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
It Is Time to Address the Crisis in the Pharmacotherapy of Posttraumatic Stress Disorder: A Consensus Statement of the PTSD Psychopharmacology Working Group
Open accessOverview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Increasing evidence suggests that these circuitry treatment effects are mediated by changes in synaptic plasticity in key areas of the circuitry (Krystal et al., 2017;Luchkina & Bolshakov, 2018;Mahan & Ressler, 2012;Mansson et al., 2016;Mansson et al., 2017).”
From Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders (2019) · cites this paper as Krystal et al., 2017
In the citing paper
“and, indeed, patients with an anxiety disorder display abnormal levels of glutamate and glutamate receptors (Krystal et al., 2017).”
From Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders (2019) · cites this paper as Krystal et al., 2017
In the citing paper
“Stress that is considered a risk factor in the development of anxiety disorders alters levels of glutamate in rodents, and, indeed, patients with an anxiety disorder display abnormal levels of glutamate and glutamate receptors (Krystal et al., 2017).”
From Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders (2019) · cites this paper as Krystal et al., 2017
Citations
Cites
Posttraumatic Stress Disorder in the National Comorbidity Survey
Kessler, R. C. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950240066012 · Cited by 10,379
Clinician-administered PTSD scale: A review of the first ten years of research
Weathers, F. W., Keane, T. M., & Davidson, J. R. T. (2001) · Depression and Anxiety · doi:10.1002/da.1029 · Cited by 1,903
Biological studies of post-traumatic stress disorder
Pitman, R. K., Rasmusson, A. M., Koenen, K. C., Shin, L. M., Orr, S. P., Gilbertson, M. W., Milad, M. R., & Liberzon, I. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3339 · Cited by 1,529
Post-Traumatic Stress Disorder in the General Population
Helzer, J. E., Robins, L. N., & McEvoy, L. (1987) · New England Journal of Medicine · doi:10.1056/nejm198712243172604 · Cited by 1,199
Sequenced treatment alternatives to relieve depression (STAR*D): Rationale and design
Rush, A. J., Fava, M., Wisniewski, S. R., Lavori, P. W., Trivedi, M. H., Sackeim, H. A., Thase, M. E., Nierenberg, A. A., Quitkin, F. M., Kashner, T. M., et al. (2004) · Controlled Clinical Trials · doi:10.1016/s0197-2456(03)00112-0 · Cited by 1,076
Medication Augmentation after the Failure of SSRIs for Depression
Trivedi, M. H., Fava, M., Wisniewski, S. R., Thase, M. E., Quitkin, F., Warden, D., Ritz, L., Nierenberg, A. A., Lebowitz, B. D., Biggs, M. M., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052964 · Cited by 1,002
Perkonigg, A., Kessler, R. C., Storz, S., & Wïttchen, H. (2000) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2000.101001046.x · Cited by 999
Thomas, J. L., Wilk, J. E., Riviere, L. A., McGurk, D., Castro, C. A., & Hoge, C. W. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.54 · Cited by 942
Efficacy and Safety of Sertraline Treatment of Posttraumatic Stress Disorder
Brady, K. T., Pearlstein, T. B., Asnis, G. M., Baker, D. G., ROTHBAUM, B. O., Sikes, C. R., & Farfel, G. M. (2000) · JAMA · doi:10.1001/jama.283.14.1837 · Cited by 707
Gaynes, B. N., Warden, D., Trivedi, M. H., Wisniewski, S. R., Fava, M., & Rush, A. J. (2009) · Psychiatric Services · doi:10.1176/ps.2009.60.11.1439 · Cited by 661
Research works printed but not linked: 2
- Shiner, 2016, Preliminary analysis of 1-year psychotropic medication receipt among VA patients with new episodes of PTSD care, 2004-2013, Ongoing VA-Funded Research
- 2013, A randomized, double-blind, placebo-controlled parallel-group, fixed-dose study evaluating the efficacy and safety of the neurokinin-1 receptor antagonist orvepitant (GW823296) in post traumatic stress disorder (PTSD), Protocol summary
Cited by
Sorted by citations
Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits
Ressler, K. J., Berretta, S., Bolshakov, V. Y., Rosso, I. M., Meloni, E. G., Rauch, S. L., & Carlezon, W. A. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00635-8 · Cited by 572
Mithoefer, M. C., Mithoefer, A. T., Feduccia, A. A., Jerome, L., Wagner, M., Wymer, J., Holland, J., Hamilton, S., Yazar-Klosinski, B., Emerson, A., et al. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30135-4 · Cited by 439
Prefrontal cortex, amygdala, and threat processing: implications for PTSD
Alexandra Kredlow, M., Fenster, R. J., Laurent, E. S., Ressler, K. J., & Phelps, E. A. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01155-7 · Cited by 346
“In contrast to the promise of current scientific approaches, in the clinic PTSD remains very difficult to treat [15, 16].”
ResultReviewing the Potential of Psychedelics for the Treatment of PTSD
Krediet, E., Bostoen, T., Breeksema, J., van Schagen, A., Passie, T., & Vermetten, E. (2020) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyaa018 · Cited by 260
Feder, A., Costi, S., Rutter, S. B., Collins, A. B., Govindarajulu, U., Jha, M. K., Horn, S. R., Kautz, M., Corniquel, M., Collins, K. A., et al. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20050596 · Cited by 246
Metadata
- Authors
- Krystal, J. H., Davis, L. L., Neylan, T. C., A. Raskind, M., Schnurr, P. P., Stein, M. B., Vessicchio, J., Shiner, B., Gleason, T. D., & Huang, G. D.
- Affiliations
- Yale University (US)
- University of Alabama (US)
- San Francisco VA Medical Center (US)
- National Center for Post Traumatic Stress Disorder (US)
- University of California San Diego (US)
- VA Connecticut Healthcare System (US)
- United States Department of Veterans Affairs (US)
- Corresponding author
- Krystal, John H.
- ORCID
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 82
- Issue
- 7
- Pages
- e51-e59
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2598895258
- Cited by
- 265
- References
- 61
- Citations by year
- 2026: 15 · 2025: 33 · 2024: 26 · 2023: 31 · 2022: 30 · 2021: 41 · 2020: 30 · 2019: 26 · 2018: 26 · 2017: 6
- FWCI
- 28.15
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biological Psychiatry (acceptedVersion)
- PubMed (publishedVersion)
- Funders
- VA Office of Research and Development Clinical Science Research & Development Service and Cooperative Studies Program
- National Institutes of Health
- Pfizer
- AstraZeneca
- National Institute on Alcohol Abuse and Alcoholism
- National Institute of Mental Health
- Department of Veterans Affairs
- Department of Defense
- Lilly Pharmaceuticals
- VA Health Services Research and Development Career Development Award
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Clinical Psychology › Migration, Health and Trauma
- Keywords
- post-traumatic stress disorder, pharmacotherapy, psychopharmacology, treatment gap, veterans, military personnel, Department of Veterans Affairs, Department of Defense
- MeSH terms
- Animals, Clinical Trials as Topic, Humans, Psychopharmacology, Psychotropic Drugs, Stress Disorders, Post-Traumatic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
