Phytosterols from Dunaliella tertiolecta and Dunaliella salina: a potentially novel industrial application
Abstract
Sterols have been extracted and analysed from Dunaliellatertiolecta and Dunaliella salina, in order to evaluate a potentially novel industrial exploitation of these microalgae as source of phytosterols. The effect of salt concentration on sterols yields has been studied varying the quantities of NaCl into culture medium. Twelve sterols were identified by Gas-chromatographic MS/MS analysis for both algal strains. The most abundant phytosterols were (22E,24R)-methylcholesta-5,7,22-trien-3beta-ol (ergosterol) and (22E,24R)-ethylcholesta-5,7,22-trien-3beta-ol (7-dehydroporiferasterol). The whole sterol fraction consisted mainly of phytosterols (C(28) and C(29) sterols). Good yields of total sterols were achieved at lower salt concentration (1.3% and 0.89% of dry weight in D. tertiolecta and D. salina, respectively, at 0.6M NaCl), while an increase in salt concentration resulted in a significant decrease in total sterols yield.
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D. tertiolecta and D. salina grown under different salt concentrations produce abundant phytosterols such as ergosterol and 7-dehydroporiferasterol.
“Francavilla et al. (2010) reported that D. tertiolecta and D. salina grown under different salt concentrations produced abundant phytosterols such as (22E, 24R)-methylcholesta-5,7,22-trien-3b-ol (ergosterol) and (22E, 24R)-ethylcholesta-5,7,22-trien-3b-ol (7-dehydroporiferasterol).”
From Microalgae Metabolites: A Rich Source for Food and Medicine (2019) · cites this paper as Francavilla et al. (2010)
Cites
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751 · see citing works
Chisti, Y. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.02.001 · Cited by 9,524 · see citing works
Recovery of microalgal biomass and metabolites: Process options and economics
Molina Grima, E., Belarbi, E.-H., Acién Fernández, F. G., Robles Medina, A., & Chisti, Y. (2003) · Biotechnology Advances · doi:10.1016/s0734-9750(02)00050-2 · Cited by 2,286 · see citing works
A review of sterol markers for marine and terrigenous organic matter
Volkman, J. K. (1986) · Organic Geochemistry · doi:10.1016/0146-6380(86)90089-6 · Cited by 1,951 · see citing works
Microalgal biomarkers: A review of recent research developments
Volkman, J. K., Barrett, S. M., Blackburn, S. I., Mansour, M. P., Sikes, E. L., & Gelin, F. (1998) · Organic Geochemistry · doi:10.1016/s0146-6380(98)00062-x · Cited by 1,258 · see citing works
Volkman, J. K. (2003) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-002-1172-8 · Cited by 854 · see citing works
Aquatic phototrophs: efficient alternatives to land-based crops for biofuels
Dismukes, G. C., Carrieri, D., Bennette, N., Ananyev, G. M., & Posewitz, M. C. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.05.007 · Cited by 733 · see citing works
Takagi, M., Karseno, & Yoshida, T. (2006) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.101.223 · Cited by 629 · see citing works
Biochemistry and Physiology of Protozoa
(1979) · Elsevier eBooks · doi:10.1016/b978-0-12-444601-4.x5001-2 · Cited by 585 · see citing works
Phytosterols: Applications and recovery methods
Fernandes, P. C. D. B., & Cabral, J. M. S. (2006) · Bioresource Technology · doi:10.1016/j.biortech.2006.10.006 · Cited by 369 · see citing works
Exploitation of Dunaliella for β-carotene production
Raja, R., Hemaiswarya, S., & Rengasamy, R. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0777-8 · Cited by 276 · see citing works
Liska, A. J., Shevchenko, A., Pick, U., & Katz, A. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.104.039438 · Cited by 269 · see citing works
ACCUMULATION OF METABOLITES BY HALOTOLERANT ALGAE AND ITS INDUSTRIAL POTENTIAL
Ben-Amotz, A., & Avron, M. (1983) · Annual Review of Microbiology · doi:10.1146/annurev.mi.37.100183.000523 · Cited by 236 · see citing works
Physiology and Biochemistry of Sterols
Patterson, G. W. (1992) · AOCS Publishing eBooks · doi:10.4324/9781003041023 · Cited by 178 · see citing works
Katz, A., Waridel, P., Shevchenko, A., & Pick, U. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700002-mcp200 · Cited by 166 · see citing works
Peeler, T. C., Stephenson, M. B., Einspahr, K. J., & Thompson, G. A. (1989) · PLANT PHYSIOLOGY · doi:10.1104/pp.89.3.970 · Cited by 102 · see citing works
Patterson, G. W. (1992) · AOCS Publishing eBooks · doi:10.1201/9781439821831.ch5 · Cited by 72 · see citing works
Zelazny, A. M., Shaish, A., & Pick, U. (1995) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.4.1395 · Cited by 56 · see citing works
Ponomarenko, L. P., Стоник, И. В., Aizdaicher, N. A., Orlova, T. Y., Popovskaya, G. I., POMAZKINA, G. V., & Stonik, V. A. (2004) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpc.2004.02.007 · Cited by 52 · see citing works
Melnikov, S. M., ten Hoorn, J. W. M. S., & Bertrand, B. (2003) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2003.08.007 · Cited by 49 · see citing works
Ergosterol production from molasses by genetically modified Saccharomyces cerevisiae
He, X., Guo, X., Liu, N., & Zhang, B. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0807-6 · Cited by 37 · see citing works
The sterols and fatty acids from purified flagella ofChlamydomonas reinhardi
Gealt, M. A., Adler, J. H., & Nes, W. R. (1981) · Lipids · doi:10.1007/bf02535687 · Cited by 33 · see citing works
Wright, J. L. C. (1979) · Canadian Journal of Chemistry · doi:10.1139/v79-415 · Cited by 27 · see citing works
Curtain, C. C., Looney, F. D., Regan, D. L., & Ivancic, N. M. (1983) · Biochemical Journal · doi:10.1042/bj2130131 · Cited by 24 · see citing works
Minor and trace sterols of Dunaliella tertiolecta
Wright, J. L. C. (1981) · Phytochemistry · doi:10.1016/s0031-9422(00)82675-8 · Cited by 20 · see citing works
Chu, F. E., Lund, E. D., Littreal, P. R., Ruck, K. E., Harvey, E. P., Coz, J., Marty, Y., Moal, J., & Soudant, P. (2008) · Marine Biology · doi:10.1007/s00227-008-1072-2 · Cited by 18 · see citing works
Unusual tetraene sterols in some phytoplankton
Patterson, G. W., Gladu, P. K., Wikfors, G. H., & Lusby, W. R. (1992) · Lipids · doi:10.1007/bf02535817 · Cited by 16 · see citing works
Ergosterol production from molasses by genetically modified Saccharomyces cerevisiae
He, Guo, Liu, Zhang, Xp, Xn, & br, B. (2007) · Cited by 14 · see citing works
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High-value products from microalgae—their development and commercialisation
Borowitzka, M. A. (2013) · Journal of Applied Phycology · doi:10.1007/s10811-013-9983-9 · Cited by 1,585 · see citing works
Microalgae Metabolites: A Rich Source for Food and Medicine
Sathasivam, R., Radhakrishnan, R., Hashem, A., & Abd_Allah, E. F. (2019) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2017.11.003 · Cited by 872 · see citing works
Screening for bioactive compounds from algae
Plaza, M., Santoyo, S., Jaime, L., Reina, G. G.-B., Herrero, M., Señoráns, F. J., & Ibáñez, E. (2009) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2009.03.016 · Cited by 493 · see citing works
Biologically Active Metabolites Synthesized by Microalgae
de Morais, M. G., Vaz, B. D. S., de Morais, E. G., & Costa, J. A. V. (2015) · BioMed Research International · doi:10.1155/2015/835761 · Cited by 471 · see citing works
Phytochemical and Potential Properties of Seaweeds and Their Recent Applications: A Review
EL-BELTAGI, H. S., Mohamed, A. A., Mohamed, H. I., Ramadan, K. M. A., Barqawi, A. A., & Mansour, A. T. (2022) · Marine Drugs · doi:10.3390/md20060342 · Cited by 384 · see citing works
Ibáñez, E., Herrero, M., Mendiola, J. A., & Castro‐Puyana, M. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1247-2_2 · Cited by 319 · see citing works
Galasso, C., Gentile, A., Orefice, I., Ianora, A., Bruno, A., Noonan, D. M., Sansone, C., Albini, A., & Brunet, C. (2019) · Nutrients · doi:10.3390/nu11061226 · Cited by 295 · see citing works
Benefits of using algae as natural sources of functional ingredients
Ibáñez, E., & Cifuentes, A. (2012) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6023 · Cited by 275 · see citing works
The Red Seaweed Gracilaria gracilis as a Multi Products Source
Francavilla, M., Franchi, M., Monteleone, M., & Caroppo, C. (2013) · Marine Drugs · doi:10.3390/md11103754 · Cited by 264 · see citing works
Microalgae-Derived Pigments: A 10-Year Bibliometric Review and Industry and Market Trend Analysis
Silva, S. C., Ferreira, I. C. F. R., Dias, M. M., & Barreiro, M. F. (2020) · Molecules · doi:10.3390/molecules25153406 · Cited by 248 · see citing works
Advances in Microalgae-Derived Phytosterols for Functional Food and Pharmaceutical Applications
Luo, X., Su, P., & Zhang, W. (2015) · Marine Drugs · doi:10.3390/md13074231 · Cited by 226 · see citing works
Characterization of extracellular polymeric substances produced by micro-algae Dunaliella salina
Mishra, A., Kavita, K., & Jha, B. (2010) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.08.067 · Cited by 220 · see citing works
Garlapati, D., Mathimani, T., Anto, S., Ahamed, T. S., Ananth, D. A., & Pugazhendhi, A. (2019) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2019.119770 · Cited by 188 · see citing works
Fal, S., Aasfar, A., Rabie, R., Smouni, A., & Arroussi, H. E. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e08811 · Cited by 152 · see citing works
Bioactive compounds in microalgae and their potential health benefits
Zhou, L., Li, K., Duan, X., Hill, D., Barrow, C., Dunshea, F., Martin, G., & Suleria, H. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.101932 · Cited by 150 · see citing works
Production, Characterization, Delivery, and Cholesterol-Lowering Mechanism of Phytosterols: A Review
Zhang, R., Han, Y., McClements, D. J., Xu, D., & Chen, S. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c07390 · Cited by 146 · see citing works
Promises and Challenges of Microalgal Antioxidant Production
Sansone, C., & Brunet, C. (2019) · Antioxidants · doi:10.3390/antiox8070199 · Cited by 136 · see citing works
Microalgae: A potential sustainable commercial source of sterols
Randhir, A., Laird, D. W., Maker, G. L., Trengove, R. D., & Moheimani, N. R. (2020) · Algal Research · doi:10.1016/j.algal.2019.101772 · Cited by 128 · see citing works
Mehariya, S., Fratini, F., Lavecchia, R., & Zuorro, A. (2021) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2021.105989 · Cited by 124 · see citing works
Ibrahim, T. N. B. T., Feisal, N. A. S., Kamaludin, N. H., Cheah, W. Y., How, V., Bhatnagar, A., Ma, Z., & Show, P. L. (2023) · Bioresource Technology · doi:10.1016/j.biortech.2023.128661 · Cited by 111 · see citing works
Cascading microalgae biorefinery: Fast pyrolysis of Dunaliella tertiolecta lipid extracted-residue
Francavilla, M., Kamaterou, P., Intini, S., Monteleone, M., & Zabaniotou, A. A. (2015) · Algal Research · doi:10.1016/j.algal.2015.06.017 · Cited by 103 · see citing works
Microwave-Mediated Pyrolysis of Macro-Algae
Budarin, V. L., Zhao, Y., Gronnow, M. J., Shuttleworth, P. S., Breeden, S. W., Macquarrie, D. J., & Clark, J. H. (2011) · Green Chemistry · doi:10.1039/c1gc15560a · Cited by 97 · see citing works
Cerón-García, M. C., Sánchez, M. D. M., Sánchez‐Mirón, A., García-Camacho, F., & Grima, E. M. (2012) · Applied Energy · doi:10.1016/j.apenergy.2012.09.054 · Cited by 97 · see citing works
Pavlova lutheri is a high-level producer of phytosterols
Ahmed, F., Zhou, W., & Schenk, P. M. (2015) · Algal Research · doi:10.1016/j.algal.2015.05.013 · Cited by 96 · see citing works
Fernandes, T., & Cordeiro, N. (2021) · Marine Drugs · doi:10.3390/md19100573 · Cited by 95 · see citing works
PHARMACEUTICALLY VALUABLE BIOACTIVE COMPOUNDS OF ALGAE
Bhattacharjee, M. (2016) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2016.v9i6.14507 · Cited by 93 · see citing works
Inhibition of fish oil oxidation and the radical scavenging activity of New Zealand seaweed extracts
Kindleysides, S., Quek, S. Y., & Miller, M. R. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.02.068 · Cited by 92 · see citing works
Biorefinery of Dunaliella salina: Sustainable recovery of carotenoids, polar lipids and glycerol
Monte, J., Ribeiro, C., Parreira, C., Costa, L., Brive, L. M., Casal, S. I. P., Brazinha, C., & Crespo, J. G. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2019.122509 · Cited by 91 · see citing works
Xia, L., Cao, J., Hu, W., Zhi, D., Tang, Y., Li, E., & He, W. (2020) · Earth-Science Reviews · doi:10.1016/j.earscirev.2020.103499 · Cited by 86 · see citing works
Recent advances in recirculating aquaculture systems and role of microalgae to close system loop
Ende, S. S. W., Henjes, J., Spiller, M., Elshobary, M. E., Hanelt, D., & Abomohra, A. (2024) · Bioresource Technology · doi:10.1016/j.biortech.2024.131107 · Cited by 95 · see citing works
Abdel-Aal, E. I., Haroon, A. M., & Mofeed, J. (2015) · The Egyptian Journal of Aquatic Research · doi:10.1016/j.ejar.2015.06.001 · Cited by 83 · see citing works
Harvesting of Dunaliella salina by membrane filtration at pilot scale
Monte, J., Sá, M., Galinha, C. F., Costa, L., Hoekstra, H., Brazinha, C., & Crespo, J. G. (2017) · Separation and Purification Technology · doi:10.1016/j.seppur.2017.08.019 · Cited by 82 · see citing works
Storage temperature and UV-irradiation influence on the ergosterol content in edible mushrooms
Villares, A., Mateo‐Vivaracho, L., Garcia-Lafuente, A. M., & Guillamón, E. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.09.144 · Cited by 77 · see citing works
Goswami, R. K., Mehariya, S., Karthikeyan, O. P., Gupta, V. K., & Verma, P. (2022) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2022.130654 · Cited by 77 · see citing works
Beta-carotene and its protective effect on gastric cancer
Chen, Q.-H., Wu, B., Pan, D., Sang, L.-X., & Chang, B. (2021) · World Journal of Clinical Cases · doi:10.12998/wjcc.v9.i23.6591 · Cited by 70 · see citing works
Francavilla, M., Colaianna, M., Zotti, M., Morgese, M. G., Trotta, P., Tucci, P., Schiavone, S., Cuomo, V., & Trabace, L. (2012) · Current Medicinal Chemistry · doi:10.2174/092986712800672021 · Cited by 70 · see citing works
Caroprese, M., Albenzio, M., Ciliberti, M. G., Francavilla, M., & Sevi, A. (2012) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2012.08.002 · Cited by 70 · see citing works
High-Value Coproducts from Algae—An Innovational Way to Deal with Advance Algal Industry
Mehta, P., Singh, D., Saxena, R., Rani, R., Gupta, R. P., Puri, S. K., & Mathur, A. S. (2017) · Energy, environment, and sustainability · doi:10.1007/978-981-10-7431-8_15 · Cited by 68 · see citing works
The microalga Dunaliella and its applications: a review
Barbosa, M., Inácio, L. G., Afonso, C., & Maranhão, P. (2023) · Applied Phycology · doi:10.1080/26388081.2023.2222318 · Cited by 65 · see citing works
Life-cycle and techno-economic analysis of utility-connected algae systems
Rickman, M., Pellegrino, J., Hock, J., Shaw, S. L., & Freeman, B. C. (2012) · Algal Research · doi:10.1016/j.algal.2012.11.003 · Cited by 62 · see citing works
Commercial‐Scale Production of Microalgae for Bioproducts
Borowitzka, M. A. (2018) · Blue Biotechnology · doi:10.1002/9783527801718.ch2 · Cited by 62 · see citing works
Alkayal, F., Albion, R. L., Tillett, R. L., Hathwaik, L. T., Lemos, M. S., & Cushman, J. C. (2010) · Plant Science · doi:10.1016/j.plantsci.2010.07.001 · Cited by 55 · see citing works
Algae and cyanobacteria as a source of novel bioactive compounds for biomedical applications
Kini, S., Divyashree, M., Mani, M. K., & Mamatha, B. S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819311-2.00012-7 · Cited by 55 · see citing works
Salinity-induced chemical, mechanical, and behavioral changes in marine microalgae
Novosel, N., Radić, T. M., Levak, M., Zemła, J., Lekka, M., Vrana, I., Gašparović, B., Horvat, L. L., Kasum, D., Legović, T., et al. (2022) · Journal of Applied Phycology · doi:10.1007/s10811-022-02734-x · Cited by 52 · see citing works
Bilbao, P., Damiani, C., Salvador, G. A., & Leonardi, P. I. (2016) · Journal of Applied Phycology · doi:10.1007/s10811-016-0899-z · Cited by 49 · see citing works
Xia, L., Cao, J., Lee, C., Stüeken, E. E., Zhi, D., & Love, G. D. (2020) · Geobiology · doi:10.1111/gbi.12423 · Cited by 49 · see citing works
The Potential of Cryptophyte Algae in Biomedical and Pharmaceutical Applications
Abidizadegan, M., Peltomaa, E., & Blomster, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.618836 · Cited by 46 · see citing works
Xia, L., Cao, J., Bian, L., Hu, W., Wang, T., Zhi, D., Tang, Y., & Li, E. (2022) · Science China Earth Sciences · doi:10.1007/s11430-021-9861-4 · Cited by 44 · see citing works
UV–C radiation increases sterol production in the microalga Pavlova lutheri
Ahmed, F., & Schenk, P. M. (2017) · Phytochemistry · doi:10.1016/j.phytochem.2017.04.002 · Cited by 40 · see citing works
Challenges and Opportunities in the Present Era of Marine Algal Applications
Beetul, K., Gopeechund, A., Kaullysing, D., Mattan-Moorgawa, S., Puchooa, D., & Bhagooli, R. (2016) · InTech eBooks · doi:10.5772/63272 · Cited by 38 · see citing works
Biotechnological Enhancement of Probiotics through Co-Cultivation with Algae: Future or a Trend?
Perković, L., Djedović, E., Vujović, T., Baković, M., Paradžik, T., & Čož‐Rakovac, R. (2022) · Marine Drugs · doi:10.3390/md20020142 · Cited by 40 · see citing works
Schepisi, E. S., Mondo, A. D., Ambrosino, L., Smerilli, A., Sansone, C., & Brunet, C. (2021) · Food Reviews International · doi:10.1080/87559129.2021.1938115 · Cited by 37 · see citing works
Hailat, I. A., & Helleur, R. J. (2013) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.6766 · Cited by 36 · see citing works
Screening for Bioactive Compounds from Algae
Herrero, M., Mendiola, J. A., Plaza, M., & Ibáñez, E. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3348-4_35 · Cited by 39 · see citing works
Pavón-Pérez, J., Agurto-Muñoz, A., Figueroa, C. P., & Agurto-Muñoz, C. (2021) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2021.106078 · Cited by 34 · see citing works
Kumar, V., Jaiswal, K. K., Tomar, M. S., Rajput, V. S., Upadhyay, S., Nanda, M., Vlaskin, M. S., Kumar, S., & KURBATOVA, A. I. (2021) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-021-01906-y · Cited by 33 · see citing works
Chlorella sorokiniana Extract Improves Short-Term Memory in Rats
Morgese, M. G., Mhillaj, E., Francavilla, M., Bové, M., Morgano, L., Tucci, P., Trabace, L., & Schiavone, S. (2016) · Molecules · doi:10.3390/molecules21101311 · Cited by 33 · see citing works
Microalgae: An Untapped Resource for Natural Antimicrobials
Jena, J., & Subudhi, E. (2018) · Springer eBooks · doi:10.1007/978-981-13-1586-2_8 · Cited by 33 · see citing works
Application of microalgae metabolites in food and pharmaceutical industry
Mishra, N., Gupta, E., Singh, P., & Prasad, R. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820284-5.00005-8 · Cited by 30 · see citing works
Cao, J., Zhang, R., Zhi, D., Tang, Y., Xia, L., & He, W. (2025) · Science China Earth Sciences · doi:10.1007/s11430-024-1525-0 · Cited by 29 · see citing works
An appraisal of the variable response of microalgal lipids to culture salinity
Cañavate, J. P., & Fernández‐Díaz, C. (2021) · Reviews in Aquaculture · doi:10.1111/raq.12592 · Cited by 29 · see citing works
Monte, J., Bernardo, J., Sá, M., Parreira, C., Galinha, C. F., Costa, L., Casanovas, C., Brazinha, C., & Crespo, J. G. (2019) · Separation and Purification Technology · doi:10.1016/j.seppur.2019.116021 · Cited by 27 · see citing works
Monte, J., Sá, M., Parreira, C., Galante, J., Serra, A. R., Galinha, C. F., Costa, L., Pereira, V. J., Brazinha, C., & Crespo, J. G. (2019) · Algal Research · doi:10.1016/j.algal.2019.101460 · Cited by 26 · see citing works
Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds
Fernandes, T., Quintana, A. M., & Cordeiro, N. (2020) · Scientific Reports · doi:10.1038/s41598-019-57188-y · Cited by 21 · see citing works
Chen, H., Wu, J., Huang, R., Dai, J.-L., Liang, M., & Jiang, J. (2024) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2024.108697 · Cited by 20 · see citing works
Derossi, A., Francavilla, M., Monteleone, M., Caporizzi, R., & Severini, C. (2021) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2021.102677 · Cited by 20 · see citing works
Fatty Acids from Microalgae: Targeting the Accumulation of Triacylglycerides
Bilbao, P., Salvador, G. A., & Leonardi, P. I. (2017) · InTech eBooks · doi:10.5772/67482 · Cited by 18 · see citing works
Safety assessment of Spirulina platensis through sprague dawley rats modeling
BASHIR, S., SHARIF, M. K., JAVED, M. S., AMJAD, A., KHAN, A. A., SHAH, F.-U.-H., & KHALIL, A. A. (2020) · Food Science and Technology · doi:10.1590/fst.41918 · Cited by 16 · see citing works
Rai, V., Patel, S. K., Muthuraj, M., Gandhi, M., Das, D., & Srivastava, S. (2021) · Biofuel Research Journal · doi:10.18331/brj2021.8.1.4 · Cited by 16 · see citing works
Bioremediation Using Microalgae and Cyanobacteria and Biomass Valorisation
Encarnação, T., Ramos, P., Danouche, M., McDonald, J., Lizzul, A. M., Nicolau, N., Campos, M. G., & SOBRAL, A. J. F. N. (2023) · Environmental challenges and solutions · doi:10.1007/978-3-031-17226-7_2 · Cited by 17 · see citing works
de Jong, D. L. C., Timmermans, K. R., de Winter, J. M., & Derksen, G. C. H. (2021) · Journal of Applied Phycology · doi:10.1007/s10811-020-02359-y · Cited by 15 · see citing works
Cañavate, J.-P., Hachero-Cruzado, I., Pérez-Gavilán, C., & Fernández-Díaz, C. (2020) · Journal of Applied Phycology · doi:10.1007/s10811-020-02258-2 · Cited by 14 · see citing works
Spray-drying optimization for Dunaliella salina and Porphyridium cruentum biomass
Konar, N., Durmaz, Y., Gürbüz, B., Polat, D. G., & Mert, B. (2023) · Drying Technology · doi:10.1080/07373937.2023.2244058 · Cited by 14 · see citing works
Wang, Y., Cao, J., Tao, K., Zhang, C., Xiang, B., Li, E., Yu, S., & Pan, C. (2023) · AAPG Bulletin · doi:10.1306/10242222027 · Cited by 14 · see citing works
Ramez, A. M., Elmahallawy, E. K., Elshopakey, G. E., Saleh, A. A., Moustafa, S. M., Albrakati, A., Abdo, W. S., & El-Shewehy, D. M. M. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.650531 · Cited by 17 · see citing works
Bagul, V. P., & Annapure, U. S. (2021) · Bioresource Technology Reports · doi:10.1016/j.biteb.2021.100688 · Cited by 13 · see citing works
Fagundes, M. B., & Wagner, R. C. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.96719 · Cited by 13 · see citing works
Ciliberti, M. G., Francavilla, M., Intini, S., Albenzio, M., Marino, R., Santillo, A., & Caroprese, M. (2017) · Marine Drugs · doi:10.3390/md15070216 · Cited by 13 · see citing works
Valdés, A., Sánchez-Martínez, J. D., Gallego, R., Ibáñez, E., Herrero, M., & Cifuentes, A. (2024) · npj Science of Food · doi:10.1038/s41538-023-00246-7 · Cited by 12 · see citing works
Woyda-Ploszczyca, A. M., & Rybak, A. S. (2021) · Algal Research · doi:10.1016/j.algal.2021.102474 · Cited by 11 · see citing works
Recent advances in microalgae-based vitamin D metabolome: Biosynthesis, and production
Ouedrhiri, W., Bennis, I., & Arroussi, H. E. (2024) · Bioresource Technology · doi:10.1016/j.biortech.2024.131078 · Cited by 10 · see citing works
Exploiting microalgal diversity for sterol production
Abdel-Karim, O. H., Wijffels, R. H., & Barbosa, M. J. (2025) · Frontiers in Plant Science · doi:10.3389/fpls.2025.1616863 · Cited by 10 · see citing works
Mass spectrometry-based metabolomics of value-added biochemicals from Ettlia oleoabundans
Matich, E. K., Butryn, D. M., Ghafari, M., del Solar, V., Camgoz, E., Pfeifer, B. A., Aga, D. S., HAZNEDAROĞLU, B. Z., & Atilla‐Gokcumen, G. E. (2016) · Algal Research · doi:10.1016/j.algal.2016.08.009 · Cited by 10 · see citing works
Li, W., Cao, J., Hu, W., Tang, Y., Xiang, B., Ma, W., He, W., Tao, K., & Wang, Y. (2023) · Fuel · doi:10.1016/j.fuel.2023.129081 · Cited by 9 · see citing works
Biorefineries: Focusing on a Closed Cycle Approach with Biogas as the Final Step
Khoshnevisan, B., & Angelidaki, İ. (2018) · Biofuel and biorefinery technologies · doi:10.1007/978-3-319-77335-3_11 · Cited by 9 · see citing works
Viêgas, C. V., Díaz, G. C., Cruz, Y. R., & Mendes, L. B. B. (2020) · American Journal of Plant Sciences · doi:10.4236/ajps.2020.1112148 · Cited by 8 · see citing works
Bioactive molecules from microalgae
Strauch, S. M., & Coutinho, P. B. D. N. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820655-3.00023-9 · Cited by 8 · see citing works
Algal Biorefinery for High-Value Platform Chemicals
HAZNEDAROĞLU, B. Z., Rismani‐Yazdi, H., Allnutt, F. C. T., Reeves, D., & Peccia, J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802980-0.00018-3 · Cited by 7 · see citing works
Bio-based nutraceuticals from biorefining
Liang, Y., & Wen, Z. (2014) · Elsevier eBooks · doi:10.1533/9780857097385.2.596 · Cited by 8 · see citing works
Qin, Z., Zhi, D., & Xi, K. (2021) · Energy Exploration & Exploitation · doi:10.1177/01445987211023856 · Cited by 6 · see citing works
Determination of Main Plant Sterols in Turkish Bread Wheat (Triticum aestivum L.) by GC-MS
Erdem, H., TOSUN, Y. K., Akkbik, M., & Hazer, O. (2017) · Turkish Journal of Agriculture - Food Science and Technology · doi:10.24925/turjaf.v5i7.710-719.1035 · Cited by 6 · see citing works
Lewandowski, I. M., Lippe, M., Castro-Montoya, J. M., Dickhoefer, U., Langenberger, G., Pucher, J., Schließmann, U., Schmid‐Staiger, U., Derwenskus, F., & Lippert, C. (2017) · Springer eBooks · doi:10.1007/978-3-319-68152-8_6 · Cited by 7 · see citing works
Microalgas: potencial para la producción de compuestos bioactivos nanoencapsulados
Mérida, L. G. R., de Menezes, C. R., Lopes, E. J., Zepka, L. Q., & Lopes, E. J. (2015) · Ciência e Natura · doi:10.5902/2179460x19690 · Cited by 5 · see citing works
Nádudvari, Á., Forzese, M., Maniscalco, R., Stefano, A. D., Misz‐Kennan, M., Marynowski, L., Krzykawski, T., & Simoneit, B. R. T. (2022) · International Journal of Coal Geology · doi:10.1016/j.coal.2022.104053 · Cited by 5 · see citing works
Novel Products from Microalgae
Subashini, G., & Bhuvaneswari, S. (2020) · Springer eBooks · doi:10.1007/978-981-15-1394-7_15 · Cited by 5 · see citing works
Zeng, J., Yang, C., Song, Q., Jia, L., & Qiu, C. (2012) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2012.10.009 · Cited by 5 · see citing works
A New γ-Pyrone from Ampelocissus artemisiifolia
Xu, Z., Yang, F. Q., Wang, L., Lu, J., Gao, D., Huang, W., & Xia, Z. (2014) · Chemistry of Natural Compounds · doi:10.1007/s10600-014-1141-3 · Cited by 4 · see citing works
Seaweed as Alternative Preservatives for Aquafeed in Asian Aquaculture
Bambaranda, B. V. A. S., Medhe, S. V., & Kamble, M. T. (2024) · Sustainability Sciences in Asia and Africa · doi:10.1007/978-981-97-4279-0_24 · Cited by 4 · see citing works
Chemical Defence by Sterols in the Freshwater Ciliate Stentor polymorphus
Buonanno, F., Trenti, F., Achille, G., Vallesi, A., Guella, G., & Ortenzi, C. (2022) · Biology · doi:10.3390/biology11121749 · Cited by 4 · see citing works
Biomarker records and mineral compositions of the Messinian halite and K–Mg salts from Sicily
Isaji, Y., Yoshimura, T., Kuroda, J., Tamenori, Y., Jiménez-Espejo, F. J., Lugli, S., Manzi, V., Roveri, M., Kawahata, H., & Ohkouchi, N. (2019) · Progress in Earth and Planetary Science · doi:10.1186/s40645-019-0306-x · Cited by 4 · see citing works
- Authors
- Francavilla, M., Trotta, P., & Luque, R.
- Affiliations
- Istituto di Scienze Marine del Consiglio Nazionale delle Ricerche (IT)
- University of Córdoba (ES)
- Corresponding author
- Francavilla, Matteo
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 101
- Issue
- 11
- Pages
- 4144-4150
- ISSN
- 0960-8524 (ISSN-L)
- OpenAlex
- W2056410449
- Cited by
- 143
- References
- 28
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 8 · 2023: 15 · 2022: 16 · 2021: 18 · 2020: 13 · 2019: 10 · 2018: 4 · 2017: 10 · 2016: 6 · 2015: 8 · 2014: 4 · 2013: 5 · 2012: 8
- FWCI
- 2.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bioresource Technology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Keywords
- phytosterols, Dunaliella tertiolecta, Dunaliella salina, microalgae, salt concentration, sodium chloride, ergosterol
- MeSH terms
- Industry, Gas Chromatography-Mass Spectrometry, Phytosterols, Species Specificity, Tandem Mass Spectrometry, Eukaryota
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