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Cited by 577

The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.

Detection principles of biological and chemical FET sensors

Open access
Kaisti, Matti·2017·Biosensors and Bioelectronics

Abstract

The seminal importance of detecting ions and molecules for point-of-care tests has driven the search for more sensitive, specific, and robust sensors. Electronic detection holds promise for future miniaturized in-situ applications and can be integrated into existing electronic manufacturing processes and technology. The resulting small devices will be inherently well suited for multiplexed and parallel detection. In this review, different field-effect transistor (FET) structures and detection principles are discussed, including label-free and indirect detection mechanisms. The fundamental detection principle governing every potentiometric sensor is introduced, and different state-of-the-art FET sensor structures are reviewed. This is followed by an analysis of electrolyte interfaces and their influence on sensor operation. Finally, the fundamentals of different detection mechanisms are reviewed and some detection schemes are discussed. In the conclusion, current commercial efforts are briefly considered.

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Metadata

Authors
Kaisti, M.
Venue
Biosensors and Bioelectronics
Publisher
Elsevier BV
Published
2017-12
Volume
98
Pages
437-448
ISSN
0956-5663 (ISSN-L)
OpenAlex
W2725266022
Cited by
577
References
111
FWCI
35.86
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Detection principles of biological and chemical FET sensors. https://app.cochat.ai/papers/10.1016/j.bios.2017.07.010
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Kaisti, M. (2017). Detection principles of biological and chemical FET sensors. Biosensors and Bioelectronics. https://doi.org/10.1016/j.bios.2017.07.010

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.