Cited by 2,134Analytical Chemistry and SensorsAnalog and Mixed-Signal Circuit DesignNeuroscience and Neural Engineering

Development of an Ion-Sensitive Solid-State Device for Neurophysiological Measurements

Bergveld, P.·1970·IEEE Transactions on Biomedical Engineering

Abstract

The development of an ion-sensitive solid-state device is described. The device combines the principles of an MOS transistor and a glass electrode and can be used for measurements of ion activities in electrochemical and biological environments. Some preliminary results are given.

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Registry

Crossref · 10.1109/tbme.1970.4502688

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5 of 5 references verified0 citation errors · 0 not checkable

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  • The early ion-sensitive FET biosensor only exhibits good sensitivity to charged biomolecules and cannot detect neutral biomolecules, which limited its applications.

    “The early ion-sensitive FET biosensor only exhibits good sensitivity to charged biomolecules but cannot detect neutral biomolecules, which limited their applications [4], [5].”

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Authors
Bergveld, P.
Corresponding author
Bergveld, P.
Venue
IEEE Transactions on Biomedical Engineering
Published
1970-01
Volume
BME-17
Issue
1
Pages
70-71
ISSN
0018-9294 (ISSN-L)
OpenAlex
W2032168109
Cited by
2,134
References
5
Citations by year
2026: 63 · 2025: 77 · 2024: 91 · 2023: 88 · 2022: 97 · 2021: 115 · 2020: 99 · 2019: 78 · 2018: 91 · 2017: 104 · 2016: 67 · 2015: 87 · 2014: 109 · 2013: 95 · 2012: 74
FWCI
1.05
Type
journal article
Language
en
Open access
closed
Locations
  • IEEE Transactions on Biomedical Engineering (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
  • Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Keywords
MOS transistors, glass electrode, ion activity measurement, electrochemical sensor, biological environment, neurophysiological measures
MeSH terms
Electrodes, Electronics, Medical, Ions, Neurophysiology

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