Development of an Ion-Sensitive Solid-State Device for Neurophysiological Measurements
Abstract
The development of an ion-sensitive solid-state device is described. The device combines the principles of an MOS transistor and a glass electrode and can be used for measurements of ion activities in electrochemical and biological environments. Some preliminary results are given.
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The early ion-sensitive FET biosensor only exhibits good sensitivity to charged biomolecules and cannot detect neutral biomolecules, which limited its applications.
“The early ion-sensitive FET biosensor only exhibits good sensitivity to charged biomolecules but cannot detect neutral biomolecules, which limited their applications [4], [5].”
From A Vertically Stacked Nanosheet Gate-All-Around FET for Biosensing Application (2021) · cites this paper as [4]
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Yin, L., Chou, J.-C., Chung, W., Sun, T., & Hsiung, S.-K. (2000) · Sensors and Actuators B Chemical · doi:10.1016/s0925-4005(00)00613-4 · Cited by 129 · see citing works
- Authors
- Bergveld, P.
- Corresponding author
- Bergveld, P.
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 1970-01
- Volume
- BME-17
- Issue
- 1
- Pages
- 70-71
- ISSN
- 0018-9294 (ISSN-L)
- OpenAlex
- W2032168109
- Cited by
- 2,134
- References
- 5
- Citations by year
- 2026: 63 · 2025: 77 · 2024: 91 · 2023: 88 · 2022: 97 · 2021: 115 · 2020: 99 · 2019: 78 · 2018: 91 · 2017: 104 · 2016: 67 · 2015: 87 · 2014: 109 · 2013: 95 · 2012: 74
- FWCI
- 1.05
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- IEEE Transactions on Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
- Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Keywords
- MOS transistors, glass electrode, ion activity measurement, electrochemical sensor, biological environment, neurophysiological measures
- MeSH terms
- Electrodes, Electronics, Medical, Ions, Neurophysiology
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