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Body composition by DXA
Open accessAbstract
Body composition measurements from DXA have been available since DXA technology was developed 30 years ago, but are historically underutilized. Recently, there have been rapid developments in body composition assessment including the analysis and publication of representative data for the US, official usage guidance from the International Society for Clinical Densitometry, and development of regional body composition measures with clinical utility. DXA body composition is much more than whole body percent fat. In this paper celebrating 30 years of DXA for body composition, we will review the principles of DXA soft tissue analysis, practical clinical and research applications, and what to look for in the future.
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“Visceral fat from the android region was estimated in this study, not calculated directly, but has a similar relationship to other biomarkers of metabolic health such as visceral fat measured by computed tomography.”
From Body composition changes during weight reduction with tirzepatide in the SURMOUNT ‐1 study of adults with obesity or overweight (2025) · cites this paper as [39]
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“DXA is also limited in the ability to accommodate patients who exceed length, width and rated load capacity”
From Body composition changes during weight reduction with tirzepatide in the SURMOUNT ‐1 study of adults with obesity or overweight (2025) · cites this paper as [39]
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Metadata
- Authors
- Shepherd, J. A., Ng, B. K., Sommer, M. J., & Heymsfield, S. B.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Shepherd, John A.
- Venue
- Bone
- Publisher
- Elsevier BV
- Published
- 2017-11
- Volume
- 104
- Pages
- 101-105
- ISSN
- 1873-2763 (ISSN-L)
- 8756-3282
- PMC
- PMC5659281
- OpenAlex
- W2626344501
- Semantic Scholar
- 240b0b4a4fee0c01cf45aeb4f4dca05e5732d9d3
- Cited by
- 460
- References
- 42
- Citations by year
- 2026: 44 · 2025: 78 · 2024: 73 · 2023: 64 · 2022: 64 · 2021: 67 · 2020: 34 · 2019: 20 · 2018: 11 · 2017: 2
- FWCI
- 13.55
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Bone (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK111698, R01DK109008, P30DK098722)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Infectious Diseases › HIV-related health complications and treatments
- Keywords
- body composition, dual-energy X-ray absorptiometry, regional body composition, soft tissue analysis, clinical application, research applications
- MeSH terms
- Body Composition, Humans, Osteoporosis, Absorptiometry, Photon, Bariatrics, Body Size
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