Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 66

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty and Cachexia

Candow, Darren G., Chilibeck, Philip D., Forbes, Scott C., Fairman, Ciaran M., Gualano, Bruno, Roschel, Hamilton·2022·Bone
DOI 10.1016/j.bone.2022.116467
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.bone.2022.116467

Cites

29 of 29 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 29 references

Research works printed but not linked: 78

  1. Candow, 2021, Current evidence and possible future applications of creatine supplementation for older adults, Nutrients, 13, 1, 10.3390/nu13030745 · DOI · Paper page
  2. Cruz-Jentoft, 2019, Sarcopenia, Lancet, 393, 2636, 10.1016/S0140-6736(19)31138-9 · DOI · Paper page
  3. Larsson, 2019, Sarcopenia: aging-related loss of muscle mass and function, Physiol. Rev., 99, 427, 10.1152/physrev.00061.2017 · DOI · Paper page
  4. Okayama, 2022, Prevalence of sarcopenia and its association with quality of life, postural stability, and past incidence of falls in postmenopausal women with osteoporosis: a cross-sectional study, Healthc. (Basel, Switzerland), 10, 192
  5. Candow, 2021, Effect of 12 months of creatine supplementation and whole-body resistance training on measures of bone, muscle and strength in older males, Nutr. Health, 27, 151, 10.1177/0260106020975247 · DOI · Paper page
  6. Candow, 2021, Efficacy of creatine supplementation and resistance training on area and density of bone and muscle in older adults, Med. Sci. Sports Exerc., 53, 2388, 10.1249/MSS.0000000000002722 · DOI · Paper page
  7. Chilibeck, 2015, Effects of creatine and resistance training on bone health in postmenopausal women, Med. Sci. Sports Exerc., 47, 1587, 10.1249/MSS.0000000000000571 · DOI · Paper page
  8. Candow, 2014, Creatine supplementation and aging musculoskeletal health, Endocrine, 45, 354, 10.1007/s12020-013-0070-4 · DOI · Paper page
  9. Fragala, 2019, Resistance training for older adults: position statement from the National Strength and conditioning association, J. Strength Cond. Res., 33, 2019, 10.1519/JSC.0000000000003230 · DOI · Paper page
  10. Bemben, 2010, The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men, J. Nutr. Health Aging, 14, 155, 10.1007/s12603-009-0124-8 · DOI · Paper page
  11. Villanueva, 2014, Periodized resistance training with and without supplementation improve body composition and performance in older men, Eur. J. Appl. Physiol., 114, 891, 10.1007/s00421-014-2821-1 · DOI
  12. Collins, 2016, Resistance training and co-supplementation with creatine and protein in older subjects with frailty, J. Frailty Aging., 5, 126
  13. Pinkoski, 2006, The effects of conjugated linoleic acid supplementation during resistance training, Med. Sci. Sports Exerc., 38, 339, 10.1249/01.mss.0000183860.42853.15 · DOI
  14. Tarnopolsky, 2007, Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults, PLoS One, 2, 10.1371/journal.pone.0000991 · DOI
  15. Gotshalk, 2002, Creatine supplementation improves muscular performance in older men, Med. Sci. Sports Exerc., 34, 537, 10.1097/00005768-200203000-00023 · DOI · Paper page
  16. Stout, 2007, Effects of creatine supplementation on the onset of neuromuscular fatigue threshold and muscle strength in elderly men and women (64 - 86 years), J. Nutr. Health Aging, 11, 459
  17. Forbes, 2021, Effects of creatine supplementation on properties of muscle, bone, and brain function in older adults: a narrative review, J. Diet. Suppl.
  18. Sales, 2020, Creatine supplementation (3 g/d) and bone health in older women: a 2-year, randomized, placebo-controlled trial, J. Gerontol. Ser. A, 75, 931, 10.1093/gerona/glz162 · DOI · Paper page
  19. Wallimann, 1994, Creatine kinase in non-muscle tissues and cells, Mol. Cell. Biochem., 133–134, 193, 10.1007/BF01267955 · DOI · Paper page
  20. Ch’ng, 1994, Transcriptional and posttranscriptional mechanisms modulate creatine kinase expression during differentiation of osteoblastic cells, J. Biol. Chem., 269, 2336, 10.1016/S0021-9258(17)42172-7 · DOI
  21. Heyden, 1970, Enzyme histochemistry and its application in comparative studies of adenosinetriphosphatase (ATPase) and some oxidative enzymes in bone, cartilage and tooth germs, Odontol. Revy., 21, 129
  22. Somjen, 1994, Stimulation by insulin-like growth factor-I of creatine kinase activity in skeletal-derived cells and tissues of male and female rats, J. Endocrinol., 143, 251, 10.1677/joe.0.1430251 · DOI
  23. Gerber, 2005, Stimulatory effects of creatine on metabolic activity, differentiation and mineralization of primary osteoblast-like cells in monolayer and micromass cell cultures, Eur. Cell. Mater., 10, 8, 10.22203/eCM.v010a02 · DOI
  24. De Souza, 2012, Influence of creatine supplementation on bone quality in the ovariectomized rat model: an FT-Raman spectroscopy study, Lasers Med. Sci., 27, 487, 10.1007/s10103-011-0976-0 · DOI
  25. Miranda, 2011, Effect of different doses of creatine on the bone in thirty days of supplementation in mice: FT-Raman study, Spectroscopy, 25, 225, 10.1155/2011/212038 · DOI
  26. Antolic, 2007, Creatine monohydrate increases bone mineral density in young Sprague-dawley rats, Med. Sci. Sports Exerc., 39, 816, 10.1249/mss.0b013e318031fac4 · DOI · Paper page
  27. Alves, 2012, Influence of creatine supplementation on bone mass of spontaneously hypertensive rats, Rev. Bras. Reumatol., 52, 453
  28. Murai, 2015, Exercise training, creatine supplementation, and bone health in ovariectomized rats, Osteoporos. Int., 26, 1395, 10.1007/s00198-014-3017-6 · DOI
  29. Rubin, 1985, Regulation of bone mass by mechanical strain magnitude, Calcif. Tissue Int., 37, 411, 10.1007/BF02553711 · DOI · Paper page
  30. Cornish, 2009, Conjugated linoleic acid combined with creatine monohydrate and whey protein supplementation during strength training, Int. J. Sport Nutr. Exerc. Metab., 19, 79, 10.1123/ijsnem.19.1.79 · DOI
  31. Gualano, 2014, Creatine supplementation and resistance training in vulnerable older women: a randomized double-blind placebo-controlled clinical trial, Exp. Gerontol., 53, 7, 10.1016/j.exger.2014.02.003 · DOI · Paper page
  32. Chilibeck, 2005, Creatine monohydrate and resistance training increase bone mineral content and density in older men, J. Nutr. Health Aging, 9, 352
  33. Pinto, 2016, Impact of creatine supplementation in combination with resistance training on lean mass in the elderly, J. Cachexia. Sarcopenia Muscle, 7, 413, 10.1002/jcsm.12094 · DOI · Paper page
  34. Forbes, 2018, Creatine supplementation during resistance training does not lead to greater bone mineral density in older humans: a brief meta-analysis, Front. Nutr., 5, 10.3389/fnut.2018.00027 · DOI
  35. Candow, 2019, Effect of pre-exercise and post-exercise creatine supplementation on bone mineral content and density in healthy aging adults, Exp. Gerontol., 119, 89, 10.1016/j.exger.2019.01.025 · DOI · Paper page
  36. Roschel, 2021, Supplement-based nutritional strategies to tackle frailty: a multifactorial, double-blind, randomized placebo-controlled trial, Clin. Nutr., 40, 4849, 10.1016/j.clnu.2021.06.024 · DOI · Paper page
  37. Forbes, 2021, A high dose of creatine combined with resistance training appears to be required to augment indices of bone health in older adults, Ann. Nutr. Metab.
  38. LaCroix, 2010, Hip structural geometry and incidence of hip fracture in postmenopausal women: what does it add to conventional bone mineral density?, Osteoporos. Int., 21, 919, 10.1007/s00198-009-1056-1 · DOI · Paper page
  39. Candow, 2021, Efficacy of creatine supplementation and resistance training on area and density of bone and muscle in older adults, Med. Sci. Sports Exerc., 53, 2388, 10.1249/MSS.0000000000002722 · DOI · Paper page
  40. Bender, 2008, Long-term creatine supplementation is safe in aged patients with parkinson disease, Nutr. Res., 28, 172, 10.1016/j.nutres.2008.01.001 · DOI · Paper page
  41. Crockett, 2018, Differences in function and fracture risk in postmenopausal women with and without a recent distal radius fracture, J. Aging Phys. Act., 26, 136, 10.1123/japa.2016-0132 · DOI
  42. MacRae, 1992, Physical performance measures that predict faller status in community-dwelling older adults, J. Orthop. Sports Phys. Ther., 16, 123, 10.2519/jospt.1992.16.3.123 · DOI · Paper page
  43. Frank-Wilson, 2016, Lower leg muscle density is independently associated with fall status in community-dwelling older adults, Osteoporos. Int., 27, 2231, 10.1007/s00198-016-3514-x · DOI · Paper page
  44. Huisingh-Scheetz, 2017, How should older adults with cancer be evaluated for frailty?, J. Geriatr. Oncol., 8, 8, 10.1016/j.jgo.2016.06.003 · DOI
  45. Guralnik, 2020, Clinically meaningful change for physical performance: perspectives of the ICFSR task force, J. Frailty Aging, 9, 9, 10.14283/jfa.2019.33 · DOI
  46. Morley, 2012, A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged african americans, J. Nutr. Health Aging, 16, 601, 10.1007/s12603-012-0084-2 · DOI · Paper page
  47. Ofori-Asenso, 2019, Global incidence of frailty and prefrailty among community-dwelling older adults: a systematic review and meta-analysis, JAMA Netw. Open, 2, 10.1001/jamanetworkopen.2019.8398 · DOI · Paper page
  48. Rohrmann, 2020, Epidemiology of frailty in older people, Adv. Exp. Med. Biol., 1216, 21, 10.1007/978-3-030-33330-0_3 · DOI
  49. Liu, 2011, Exercise as an intervention for frailty, Clin. Geriatr. Med., 27, 101, 10.1016/j.cger.2010.08.001 · DOI
  50. Jadczak, 2016, Effectiveness of exercise interventions on physical function in community-dwelling frail older people: an umbrella review protocol, JBI Database Syst. Rev. Implement. Rep., 14, 93, 10.11124/JBISRIR-2016-003081 · DOI
  51. Avgerinos, 2018, Effects of creatine supplementation on cognitive function of healthy individuals: a systematic review of randomized controlled trials, Exp. Gerontol., 108, 173, 10.1016/j.exger.2018.04.013 · DOI · Paper page
  52. Pires, 2020, Creatine supplementation on cognitive performance following creatine supplementation on cognitive performance following exercise in female muay thai athletes exercise in female muay thai athletes, J. Soc. NeuroSports, 1
  53. Forbes, 2022, Effects of creatine supplementation on brain function and health, Nutrients, 14, 921, 10.3390/nu14050921 · DOI · Paper page
  54. Nomura, 2003, Anti-inflammatory activity of creatine supplementation in endothelial cells in vitro, Br. J. Pharmacol., 139, 715, 10.1038/sj.bjp.0705316 · DOI
  55. Aoyagi, 2015, Cancer cachexia, mechanism and treatment, worldJ Gastrointest. Oncol., 7, 17, 10.4251/wjgo.v7.i4.17 · DOI · Paper page
  56. Baracos, 2018, Cancer-associated cachexia, Nat. Rev. Dis. Prim., 4
  57. Aversa, 2017, Cancer-induced muscle wasting: latest findings in prevention and treatment, Ther. Adv. Med. Oncol., 9, 369, 10.1177/1758834017698643 · DOI
  58. Vaughan, 2013, Cancer cachexia: impact, mechanisms and emerging treatments, J. Cachexia. Sarcopenia Muscle, 4, 95, 10.1007/s13539-012-0087-1 · DOI
  59. Morley, 2006, Cachexia: pathophysiology and clinical relevance, Am. J. Clin. Nutr., 83, 735, 10.1093/ajcn/83.4.735 · DOI · Paper page
  60. Koppe, 2019, Kidney cachexia or protein-energy wasting in chronic kidney disease: facts and numbers, J. Cachexia. Sarcopenia Muscle, 10, 479, 10.1002/jcsm.12421 · DOI
  61. Fearon, 2011, Definition and classification of cancer cachexia: an international consensus, LancetOncologia, 12, 489
  62. Blum, 2014, Validation of the consensus-definition for cancer cachexia and evaluation of a classification model--a study based on data from an international multicentre project (EPCRC-CSA), Ann. Oncol. Off. J. Eur. Soc. Med. Oncol., 25, 1635, 10.1093/annonc/mdu086 · DOI · Paper page
  63. Dunne, 2017, Research priorities in cancer cachexia: the University of Rochester Cancer Center NCI Community Oncology Research Program Research Base Symposium on cancer cachexia and sarcopenia, Curr. Opin. Support. Palliat. Care, 11, 278, 10.1097/SPC.0000000000000301 · DOI
  64. Johns, 2014, Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle, PLoS One, 9, 10.1371/journal.pone.0083618 · DOI
  65. Jatoi, 2017, A double-blind, placebo-controlled randomized trial of creatine for the cancer anorexia/weight loss syndrome (N02C4): an alliance trial, Ann. Oncol. Off. J. Eur. Soc. Med. Oncol., 28, 1957, 10.1093/annonc/mdx232 · DOI
  66. Norman, 2006, Effects of creatine supplementation on nutritional status, muscle function and quality of life in patients with colorectal cancer–a double blind randomised controlled trial, Clin. Nutr., 25, 596, 10.1016/j.clnu.2006.01.014 · DOI
  67. Antunes, 2018, Exercise training as therapy for cancer-induced cardiac cachexia, Trends Mol. Med., 24, 709, 10.1016/j.molmed.2018.06.002 · DOI
  68. Bosaeus, 2008, Nutritional support in multimodal therapy for cancer cachexia, Support Care Cancer, 16, 447
  69. Lonbro, 2013, Feasibility and efficacy of progressive resistance training and dietary supplements in radiotherapy treated head and neck cancer patients–the DAHANCA 25A study, Acta Oncol., 52, 310, 10.3109/0284186X.2012.741325 · DOI
  70. Fairman, 2019, Examining the effects of creatine supplementation in augmenting adaptations to resistance training in patients with prostate cancer undergoing androgen deprivation therapy: a randomised, double-blind, placebo-controlled trial, BMJ Open, 9, 10.1136/bmjopen-2019-030080 · DOI
  71. Aguiar, 2013, Long-term creatine supplementation improves muscular performance during resistance training in older women, Eur. J. Appl. Physiol., 113, 987, 10.1007/s00421-012-2514-6 · DOI · Paper page
  72. Deacon, 2008, Randomized controlled trial of dietary creatine as an adjunct therapy to physical training in chronic obstructive pulmonary disease, Am. J. Respir. Crit. Care Med., 178, 233, 10.1164/rccm.200710-1508OC · DOI
  73. Eijnde, 2003, Effects of creatine supplementation and exercise training on fitness in men 55–75 yr old, J. Appl. Physiol., 95, 818, 10.1152/japplphysiol.00891.2002 · DOI · Paper page
  74. Hass, 2007, Resistance training with creatine monohydrate improves upper-body strength in patients with Parkinson disease: a randomized trial, Neurorehabil. Neural Repair, 21, 107, 10.1177/1545968306293449 · DOI
  75. Smolarek, 2020, Effect of 16 Weeks of Strength Training and Creatine Supplementation on Strength and Cognition in Older Adults: A Pilot Study, J. Exerc. Physiol., 23
  76. Bermon, 1998, Effects of creatine monohydrate ingestion in sedentary and weight-trained older adults, Acta Physiol. Scand., 164, 147, 10.1046/j.1365-201X.1998.00427.x · DOI · Paper page
  77. Bernat, 2019, Effects of high-velocity resistance training and creatine supplementation in untrained healthy aging males, Appl. Physiol. Nutr. Metab., 44, 1246, 10.1139/apnm-2019-0066 · DOI
  78. Candow, 2015, Strategic creatine supplementation and resistance training in healthy older adults, Appl. Physiol. Nutr. Metab., 40, 689, 10.1139/apnm-2014-0498 · DOI · Paper page

Cited by

Metadata

Authors
Candow, D. G., Chilibeck, P. D., Forbes, S. C., Fairman, C. M., Gualano, B., & Roschel, H.
Venue
Bone
Publisher
Elsevier BV
Published
2022-09
Volume
162
Pages
116467
ISSN
8756-3282
DOI
10.1016/j.bone.2022.116467
Cited by
66
References
29
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.