Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP

Inference of macromolecular assemblies from crystalline state.

Krissinel, E., & Henrick, K. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2007.05.022 · Cited by 10,189 · see citing works

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Rao, S. S. P., Huntley, M. H., Durand, N. C., Stamenova, E. K., Bochkov, I. D., Robinson, J. T., Sanborn, A. L., Machol, I., Omer, A. D., Lander, E. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.021 · Cited by 9,212 · see citing works

The nuclear receptor superfamily: the second decade

Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90199-x · Cited by 6,964 · see citing works

I-TASSER server for protein 3D structure prediction

Zhang, Y. (2008) · BMC Bioinformatics · doi:10.1186/1471-2105-9-40 · Cited by 5,124 · see citing works

The FoldX web server: an online force field

Schymkowitz, J., Borg, J., Stricher, F., Nys, R., Rousseau, F., & Serrano, L. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki387 · Cited by 2,759 · see citing works

Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome

Kornberg, R. D., & Lorch, Y. (1999) · Cell · doi:10.1016/s0092-8674(00)81958-3 · Cited by 1,833 · see citing works

Protein Structure Prediction and Structural Genomics

Baker, D., & Sali, A. (2001) · Science · doi:10.1126/science.1065659 · Cited by 1,587 · see citing works

CCAAT/enhancer-binding proteins: structure, function and regulation

Ramji, D. P., & Foka, P. (2002) · Biochemical Journal · doi:10.1042/bj20020508 · Cited by 1,401 · see citing works

ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION

Workman, J. L., & Kingston, R. E. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.545 · Cited by 1,129 · see citing works

A large-scale evaluation of computational protein function prediction

Radivojac, P., Clark, W. T., Oron, T. R., Schnoes, A. M., Wittkop, T., Sokolov, A., Graim, K., Funk, C., Verspoor, K., Ben-Hur, A., et al. (2013) · Nature Methods · doi:10.1038/nmeth.2340 · Cited by 1,028 · see citing works

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex

Ellenberger, T. E., Brandl, C. J., Struhl, K., & Harrison, S. C. (1992) · Cell · doi:10.1016/s0092-8674(05)80070-4 · Cited by 972 · see citing works

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

John, S., Sabo, P. J., Thurman, R. E., Sung, M.-H., Biddie, S. C., Johnson, T. A., Hager, G. L., & Stamatoyannopoulos, J. A. (2011) · Nature Genetics · doi:10.1038/ng.759 · Cited by 954 · see citing works

Impaired Energy Homeostasis in C/EBPα Knockout Mice

Wang, N.-D., Finegold, M. J., Bradley, A., Ou, C. N., Abdelsayed, S. V., Wilde, M. D., Taylor, L. R., Wilson, D. R., & Darlington, G. J. (1995) · Science · doi:10.1126/science.7652557 · Cited by 929 · see citing works

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

Zhang, D.-E., Zhang, P., Wang, N.-D., Hetherington, C. J., Darlington, G. J., & Tenen, D. G. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.2.569 · Cited by 910 · see citing works

Glucocorticoid receptor signaling in health and disease

Kadmiel, M., & Cidlowski, J. A. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.07.003 · Cited by 849 · see citing works

The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

McNally, J. G., Müller, W. G., Walker, D., Wolford, R., & Hager, G. L. (2000) · Science · doi:10.1126/science.287.5456.1262 · Cited by 802 · see citing works

ATP-Dependent Nucleosome Remodeling

Becker, P. B., & Hörz, W. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135400 · Cited by 790 · see citing works

ATP-Dependent Chromatin-Remodeling Complexes

Vignali, M., Hassan, A. H., Neely, K. E., & Workman, J. L. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.6.1899-1910.2000 · Cited by 731 · see citing works

Diversity and specialization of mammalian SWI/SNF complexes.Preprint

Wang, W., Xue, Y., Zhou, S., Kuo, A. C., Cairns, B. R., & Crabtree, G. R. (1996) · Genes & Development · doi:10.1101/gad.10.17.2117 · Cited by 707 · see citing works

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

Peterson, C. L., & Herskowitz, I. (1992) · Cell · doi:10.1016/0092-8674(92)90192-f · Cited by 601 · see citing works

Chromatin remodelling: the industrial revolution of DNA around histones

Saha, A., Wittmeyer, J., & Cairns, B. R. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1945 · Cited by 590 · see citing works

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

Winston, F., & Carlson, M. (1992) · Trends in Genetics · doi:10.1016/0168-9525(92)90300-s · Cited by 574 · see citing works

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

Fryer, C. J., & Archer, T. K. (1998) · Nature · doi:10.1038/30032 · Cited by 511 · see citing works

Mapping the Number of Molecules and Brightness in the Laser Scanning Microscope

Digman, M. A., Dalal, R. B., Horwitz, A. F., & Gratton, E. (2007) · Biophysical Journal · doi:10.1529/biophysj.107.114645 · Cited by 477 · see citing works

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

Yoshinaga, S. K., Peterson, C. L., Herskowitz, I., & Yamamoto, K. R. (1992) · Science · doi:10.1126/science.1360703 · Cited by 477 · see citing works

Promoter targeting and chromatin remodeling by the SWI/SNF complex

Peterson, C. L., & Workman, J. L. (2000) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00068-x · Cited by 438 · see citing works

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

Stavreva, D. A., Wiench, M., John, S., Conway-Campbell, B. L., McKenna, M. A., Pooley, J. R., Johnson, T. A., Voss, T. C., Lightman, S. L., & Hager, G. L. (2009) · Nature Cell Biology · doi:10.1038/ncb1922 · Cited by 375 · see citing works

Computational methods for the prediction of protein interactions

Valencia, A., & Pazos, F. (2002) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(02)00333-0 · Cited by 353 · see citing works

Prediction of water and metal binding sites and their affinities by using the Fold-X force field

Schymkowitz, J. W. H., Rousseau, F., Martins, I. C., Ferkinghoff‐Borg, J., Stricher, F., & Serrano, L. G. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501980102 · Cited by 340 · see citing works

Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription

Collingwood, T., Urnov, F. D., & Wolffe, A. P. (1999) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0230255 · Cited by 318 · see citing works

Utility of homology models in the drug discovery process

Hillisch, A., Pineda, L. F., & Hilgenfeld, R. (2004) · Drug Discovery Today · doi:10.1016/s1359-6446(04)03196-4 · Cited by 315 · see citing works

Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism

Voss, T. C., Schiltz, R. L., Sung, M.-H., Yen, P. M., Stamatoyannopoulos, J. A., Biddie, S. C., Johnson, T. A., Miranda, T. B., John, S., & Hager, G. L. (2011) · Cell · doi:10.1016/j.cell.2011.07.006 · Cited by 307 · see citing works

SWI2/SNF2 and Related Proteins: ATP-Driven Motors That Disrupt-Protein–DNA Interactions?

Pazin, M. J., & Kadonaga, J. T. (1997) · Cell · doi:10.1016/s0092-8674(00)81918-2 · Cited by 307 · see citing works

A C/EBPβ Isoform Recruits the SWI/SNF Complex to Activate Myeloid Genes

Kowenz‐Leutz, E., & Leutz, A. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80384-6 · Cited by 301 · see citing works

A Specificity and Targeting Subunit of a Human SWI/SNF Family-Related Chromatin-Remodeling Complex

Nie, Z., Xue, Y., Yang, D., Zhou, S., Deroo, B. J., Archer, T., & Wang, W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.23.8879-8888.2000 · Cited by 298 · see citing works

Predicting protein-protein interactions on a proteome scale by matching evolutionary and structural similarities at interfaces using PRISM

Tunçbağ, N., Gürsoy, A., Nussinov, R., & Keskin, Ö. (2011) · Nature Protocols · doi:10.1038/nprot.2011.367 · Cited by 264 · see citing works

Selectivity of chromatin-remodelling cofactors for ligand-activated transcription

Lemon, B. D., Inouye, C. J., King, D., & Tjian, R. (2001) · Nature · doi:10.1038/414924a · Cited by 263 · see citing works

Propagation of adipogenic signals through an epigenomic transition statePreprint

Steger, D. J., Grant, G. R., Schupp, M., Tomaru, T., Lefterova, M. I., Schug, J., Manduchi, E., Stoeckert, C. J., & Lazar, M. A. (2010) · Genes & Development · doi:10.1101/gad.1907110 · Cited by 249 · see citing works

PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genesPreprint

Yan, Z., Cui, K., Murray, D., Chen, L., Xue, Y., Gerstein, A. V., Parsons, R. E., Zhao, K., & Wang, W. (2005) · Genes & Development · doi:10.1101/gad.1323805 · Cited by 247 · see citing works

C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements

Grøntved, L., John, S., Baek, S., Liu, Y., Buckley, J. R., Vinson, C., Aguilera, G., & Hager, G. L. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.106 · Cited by 229 · see citing works

NOXclass: prediction of protein-protein interaction types

Zhu, H., Domingues, F. S., Sommer, I., & Lengauer, T. (2006) · BMC Bioinformatics · doi:10.1186/1471-2105-7-27 · Cited by 210 · see citing works

BAF60a Mediates Critical Interactions between Nuclear Receptors and the BRG1 Chromatin-Remodeling Complex for Transactivation

Hsiao, P., Fryer, C. J., Trotter, K. W., Wang, W., & Archer, T. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.17.6210-6220.2003 · Cited by 202 · see citing works

PRISM: a web server and repository for prediction of protein–protein interactions and modeling their 3D complexes

Baspinar, A., Cukuroglu, E., Nussinov, R., Keskin, Ö., & Gürsoy, A. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku397 · Cited by 201 · see citing works

Cooperation between C/EBPα TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiationPreprint

Pedersen, T. Å., Kowenz‐Leutz, E., Leutz, A., & Nerlov, C. (2001) · Genes & Development · doi:10.1101/gad.209901 · Cited by 196 · see citing works

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Rochel, N., Ciesielski, F., Godet, J., Momán, E., Roessle, M. W., Peluso‐Iltis, C., Moulin, M., Haertlein, M., Callow, P., Mély, Y., et al. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2054 · Cited by 193 · see citing works

HDAC1 Acetylation Is Linked to Progressive Modulation of Steroid Receptor-Induced Gene Transcription

Qiu, Y., Zhao, Y., Becker, M., John, S., Parekh, B. S., Huang, S., Hendarwanto, A., Martínez, E. D., Chen, Y., Lu, H., et al. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.04.019 · Cited by 184 · see citing works

Yeast SNF2/SWI2, SNF5, and SNF6 proteins function coordinately with the gene-specific transcriptional activators GAL4 and Bicoid.Preprint

Laurent, B. C., & Carlson, M. (1992) · Genes & Development · doi:10.1101/gad.6.9.1707 · Cited by 155 · see citing works

Protein interface classification by evolutionary analysis

Duarte, J. M., Srebniak, A., Schärer, M. A., & Capitani, G. (2012) · BMC Bioinformatics · doi:10.1186/1471-2105-13-334 · Cited by 141 · see citing works

Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor

Presman, D. M., Ogara, M. F., Stortz, M., Álvarez, L. D., Pooley, J. R., Schiltz, R. L., Grøntved, L., Johnson, T. A., Mittelstadt, P. R., Ashwell, J. D., et al. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001813 · Cited by 138 · see citing works

DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation

Chen, Y., Bates, D. L., Dey, R., Chen, P., Machado, A. C. D., Laird‐Offringa, I. A., Rohs, R., & Chen, L. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.10.012 · Cited by 117 · see citing works

Evolutionary profiles improve protein–protein interaction prediction from sequence

Hamp, T., & Rost, B. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btv077 · Cited by 117 · see citing works

Association of DNA-bound progesterone receptors

Théveny, B., Bailly, A., Rauch, C., Rauch, M., Delain, E., & Milgröm, E. (1987) · Nature · doi:10.1038/329079a0 · Cited by 106 · see citing works

Chromatin remodeling by nuclear receptors

Hebbar, P. B., & Archer, T. (2003) · Chromosoma · doi:10.1007/s00412-003-0232-x · Cited by 106 · see citing works

HotRegion: a database of predicted hot spot clusters

Cukuroglu, E., Gürsoy, A., & Keskin, Ö. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr929 · Cited by 99 · see citing works

Using Inducible Vectors to Study Intracellular Trafficking of GFP-Tagged Steroid/Nuclear Receptors in Living Cells

Walker, D. A., Htun, H., & Hager, G. L. (1999) · Methods · doi:10.1006/meth.1999.0874 · Cited by 98 · see citing works

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

Goswami, D., Devarakonda, S., Chalmers, M. J., Pascal, B. D., Spiegelman, B. M., & Griffin, P. R. (2013) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-013-0669-y · Cited by 77 · see citing works

Interaction of C/EBPα and the glucocorticoid receptor in vivo and in nontransformed human cells

Rüdiger, J. J., Roth, M., Bihl, M., Cornelius, B., Johnson, M. W., Ziesche, R., & Block, L. H. (2002) · The FASEB Journal · doi:10.1096/fj.01-0226com · Cited by 70 · see citing works

The HSA Domain of BRG1 Mediates Critical Interactions Required for Glucocorticoid Receptor-Dependent Transcriptional Activation In Vivo

Trotter, K. W., Fan, H.-Y., Ivey, M. L., Kingston, R. E., & Archer, T. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01301-07 · Cited by 65 · see citing works

Constructing structural networks of signaling pathways on the proteome scale

Kuzu, G., Keskin, Ö., Gürsoy, A., & Nussinov, R. (2012) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2012.04.004 · Cited by 64 · see citing works

Human Proteome-scale Structural Modeling of E2–E3 Interactions Exploiting Interface Motifs

Kar, G., Keskin, Ö., Nussinov, R., & Gürsoy, A. (2011) · Journal of Proteome Research · doi:10.1021/pr2009143 · Cited by 54 · see citing works

Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP

Johansson-Haque, K., Palanichamy, E., & Okret, S. (2008) · Journal of Molecular Endocrinology · doi:10.1677/jme-08-0015 · Cited by 53 · see citing works

Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids

Presman, D. M., Álvarez, L. D., Levi, V., Eduardo, S. L., Digman, M. A., Marti, M. A., Veleiro, A. S., Burton, G., & Pecci, A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013279 · Cited by 51 · see citing works

Exploring the transcription–chromatin interface: Figure 1.Preprint

Jones, K. A., & Kadonaga, J. T. (2000) · Genes & Development · doi:10.1101/gad.14.16.1992 · Cited by 49 · see citing works

Exploiting Conformational Ensembles in Modeling Protein–Protein Interactions on the Proteome Scale

Kuzu, G., Gursoy, A., Nussinov, R., & Keskin, O. (2013) · Journal of Proteome Research · doi:10.1021/pr400006k · Cited by 47 · see citing works

iLoops: a protein–protein interaction prediction server based on structural features

Planas-Iglesias, J., Marín-López, M. A., Bonet, J., Garcı́a-Garcı́a, J., & Oliva, B. (2013) · Bioinformatics · doi:10.1093/bioinformatics/btt401 · Cited by 47 · see citing works

Chromatin remodeling and tissue-selective responses of nuclear hormone receptors.

Hsiao, P., Deroo, B., & Archer, T. (2002) · Biochemistry and cell biology = Biochimie et biologie cellulaire · doi:10.1139/o02-082 · Cited by 42 · see citing works

Evaluating template-based and template-free protein-protein complex structure prediction

Vreven, T., Hwang, H., Pierce, B. G., & Weng, Z. (2013) · Briefings in Bioinformatics · doi:10.1093/bib/bbt047 · Cited by 41 · see citing works

DNA-looping by RXR Tetramers Permits Transcriptional Regulation “at a Distance”

Yasmin, R., Yeung, K. T., Chung, R. H., Gaczynska, M. E., Osmulski, P. A., & Noy, N. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.08.070 · Cited by 36 · see citing works

Enriching the human apoptosis pathway by predicting the structures of protein–protein complexes

Acuner, S. E., Keskin, Ö., Nussinov, R., & Gürsoy, A. (2012) · Journal of Structural Biology · doi:10.1016/j.jsb.2012.02.002 · Cited by 33 · see citing works

At a Distance

Coonin, B. R. (2011) · Internet Reference Services Quarterly · doi:10.1080/10875301.2011.571970 · Cited by 31 · see citing works

Impaired hepatocyte maturation, abnormal expression of biliary transcription factors and liver fibrosis in C/EBPα(Cebpa)-knockout mice.

Akai, Y., Oitate, T., Koike, T., & Shiojiri, N. (2014) · PubMed · doi:10.14670/hh-29.107 · Cited by 26 · see citing works

Visualization by BiFC of different C/EBPβ dimers and their interaction with HP1α reveals a differential subnuclear distribution of complexes in living cells

Susperreguy, S., Prendes, L. P., Desbats, M. A., Charó, N. L., Brown, K. E., MacDougald, O. A., Kerppola, T. K., Schwartz, J., & Piwien‐Pilipuk, G. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.11.008 · Cited by 17 · see citing works

Association of the glucocorticoid receptor with STAT3, C/EBPβ, and the hormone‐responsive element within the rat haptoglobin gene promoter during the acute phase response

Јovanović, J. A., Poznanović, G., Ivanović‐Matić, S., Bogojević, D., Mihailović, M., Uskoković, A. S., & Grigorov, I. (2010) · IUBMB Life · doi:10.1002/iub.313 · Cited by 12 · see citing works

Accurate prediction of interfacial residues in two‐domain proteins using evolutionary information: Implications for three‐dimensional modeling

Bhaskara, R. M., Padhi, A., & Srinivasan, N. (2013) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.24486 · Cited by 7 · see citing works

Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Weikum, E. R., Knuesel, M. T., Ortlund, E. A., & Yamamoto, K. R. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.152 · Cited by 533 · see citing works

Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246 · see citing works

DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

Presman, D. M., Ganguly, S., Schiltz, R. L., Johnson, T. A., Karpova, T., & Hager, G. L. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1606774113 · Cited by 142 · see citing works

Quantifying transcription factor binding dynamics at the single-molecule level in live cells

Presman, D. M., Ball, D. A., Paakinaho, V., Grimm, J. B., Lavis, L. D., Karpova, T., & Hager, G. L. (2017) · Methods · doi:10.1016/j.ymeth.2017.03.014 · Cited by 102 · see citing works

Mechanistic Insights Into the Interaction Between Transcription Factors and Epigenetic Modifications and the Contribution to the Development of Obesity

Huang, Q., Ma, C., Chen, L., Luo, D., Chen, R., & Liang, F. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00370 · Cited by 78 · see citing works

Endocrine disruptors of sex hormone activities

Varticovski, L., Stavreva, D. A., McGowan, A., Raziuddin, R., & Hager, G. L. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111415 · Cited by 75 · see citing works

Glucocorticoid Receptor: A Multifaceted Actor in Breast Cancer

Noureddine, L. M., Trédan, O., Hussein, N., Badran, B. M., Romancer, M. L., & Poulard, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094446 · Cited by 55 · see citing works

Histone Modifications in Major Depressive Disorder and Related Rodent Models

Deussing, J. M., & Jakovcevski, M. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-53889-1_9 · Cited by 46 · see citing works

Multifaceted Control of GR Signaling and Its Impact on Hepatic Transcriptional Networks and Metabolism

Præstholm, S. M., Correia, C. M., & Grøntved, L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.572981 · Cited by 44 · see citing works

Stress, glucocorticoid signaling pathway, and metabolic disorders

de Guia, R. M. (2020) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2020.06.038 · Cited by 43 · see citing works

Dynamic switching of transcriptional regulators between two distinct low-mobility chromatin states

Wagh, K., Stavreva, D. A., Jensen, R. A., Paakinaho, V., Fettweis, G., Schiltz, R. L., Wüstner, D., Mandrup, S., Presman, D. M., Upadhyaya, A., et al. (2023) · Science Advances · doi:10.1126/sciadv.ade1122 · Cited by 42 · see citing works

Low-activity programming of the PDGFRβ/FAK pathway mediates H-type vessel dysplasia and high susceptibility to osteoporosis in female offspring rats after prenatal dexamethasone exposure

Shangguan, Y., Wu, Z., Xie, X., Zhou, S., He, H., Xiao, H., Liu, L., Zhu, J., Chen, H., Han, H., et al. (2021) · Biochemical Pharmacology · doi:10.1016/j.bcp.2021.114414 · Cited by 35 · see citing works

Domain architecture of BAF250a reveals the ARID and ARM-repeat domains with implication in function and assembly of the BAF remodeling complex

Sandhya, S., Maulik, A., Giri, M., & Singh, M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0205267 · Cited by 31 · see citing works

Short-Term Responders of Non–Small Cell Lung Cancer Patients to EGFR Tyrosine Kinase Inhibitors Display High Prevalence of TP53 Mutations and Primary Resistance Mechanisms

Xu, Y., Tong, X., Yan, J., Wu, X., Shao, Y. W., & Fan, Y. (2018) · Translational Oncology · doi:10.1016/j.tranon.2018.08.010 · Cited by 29 · see citing works

Mechanisms behind context-dependent role of glucocorticoids in breast cancer progression

Butz, H., & Patócs, A. (2022) · Cancer and Metastasis Reviews · doi:10.1007/s10555-022-10047-1 · Cited by 27 · see citing works

The developmental and pathogenic roles of BAF57, a special subunit of the BAF chromatin‐remodeling complex

Lomelı́, H., & Castillo‐Robles, J. (2016) · FEBS Letters · doi:10.1002/1873-3468.12201 · Cited by 24 · see citing works

Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism

Zhang, P., Li, L., Bao, Z., & Huang, F. (2016) · Nutrition & Metabolism · doi:10.1186/s12986-016-0090-1 · Cited by 25 · see citing works

Regulation of metabolic homeostasis by the TGF‐β superfamily receptor ALK7

Ibáñez, C. F. (2021) · FEBS Journal · doi:10.1111/febs.16090 · Cited by 21 · see citing works

Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance

Li, J., Xu, J., Jiang, H., Zhang, T., Ramakrishnan, A., Shen, L., & Xu, P.-X. (2021) · Journal of the American Society of Nephrology · doi:10.1681/asn.2021040525 · Cited by 18 · see citing works

Data for "Dynamic switching of transcriptional regulators between two distinct low-mobility chromatin states"

Wagh, K., Stavreva, D. A., Jensen, R. A., Paakinaho, V., Fettweis, G., Schiltz, R. L., Wüstner, D., Mandrup, S., Presman, D. M., Upadhyaya, A., et al. (2023) · UEF eRepo (University of Eastern Finland) · doi:10.5281/zenodo.7558777 · Cited by 19 · see citing works

SKOV3 cells containing a truncated ARID1a protein have a restricted genome-wide response to glucocorticoids

Stubbs, F. E., Birnie, M. T., Biddie, S. C., Lightman, S. L., & Conway-Campbell, B. L. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.09.018 · Cited by 17 · see citing works

Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

Mármol, P., Krapacher, F. A., & Ibáñez, C. F. (2020) · eLife · doi:10.7554/elife.54721 · Cited by 16 · see citing works

An integrated approach to elucidate signaling pathways of dioscin-induced apoptosis, energy metabolism and differentiation in acute myeloid leukemia

Chan, S., Liang, P., & Guh, J. (2018) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-018-1484-6 · Cited by 16 · see citing works

Transglutaminase 2 mediates transcriptional regulation through BAF250a polyamination

Kim, H.-J., Lee, J.-H., Cho, S., Jeon, J., & Kim, I. G. (2021) · Genes & Genomics · doi:10.1007/s13258-021-01055-6 · Cited by 15 · see citing works

20‐Hydroxyecdysone receptor‐activated Bombyx mori CCAAT/enhancer‐binding protein gamma regulates the expression of BmCBP and subsequent histone H3 lysine 27 acetylation in Bo. mori

Lyu, H., Xu, G., Chen, P., Song, Q., Feng, Q., Yi, Y., & Zheng, S. (2019) · Insect Molecular Biology · doi:10.1111/imb.12630 · Cited by 12 · see citing works

Epigenetic aging in major depressive disorder: Clocks, mechanisms and therapeutic perspectives

Shaikh, M., & Doshi, G. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176757 · Cited by 12 · see citing works

BRG1 defines a genomic subset of inflammatory genes transcriptionally controlled by the glucocorticoid receptorPreprint

Mechtidou, A., Greulich, F., Strickland, B. A., Jouffe, C., Cernilogar, F. M., Schotta, G., & Uhlenhaut, N. H. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.13.472398 · Cited by 6 · see citing works

InteractoMIX: a suite of computational tools to exploit interactomes in biological and clinical research

Poglayen, D., Marín-López, M. A., Bonet, J., Fornés, O., Garcı́a-Garcı́a, J., Planas-Iglesias, J., Segura, J., Oliva, B., & Fernández‐Fuentes, N. (2016) · Biochemical Society Transactions · doi:10.1042/bst20150001 · Cited by 5 · see citing works

Role of chromatin remodeling complex SWI/SNF and VDR in chronic rhinosinusitis

Kowalik, K., Waniewska-Łęczycka, M., Sarnowska, E. A., Rusetska, N., Sierdziński, J., & Zagor, M. (2020) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/117683 · Cited by 5 · see citing works

A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer

Dorso, M. A., Patel, P. T., Pankov, A., Boyer, J. A., Soni, R. K., Priore, I. S. D., Hayatt, O., Kulick, A. R., Hagen, C. J., de Stanchina, E., et al. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0310 · Cited by 4 · see citing works

Epigenomic Modulators and Thyroid Hormone Receptor β Agonists: A New Paradigm for Tumor Suppression in Thyroid Cancer

Rustad, J. L., Gillis, N. E., Lignos, J. M., Bright, K. A., Frietze, S. E., & Carr, F. E. (2025) · Endocrinology · doi:10.1210/endocr/bqaf116 · Cited by 3 · see citing works

Epigenetics and Chromatin Remodeling

Kinyamu, H. K., Mackey, L. C., Crusselle‐Davis, V. J., & Archer, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65388-6

Twenty-First Century Glucocorticoid Receptor Molecular Biology

Wang, C., Oldenkamp, R., Oellers, R., & Logie, C. (2018) · InTech eBooks · doi:10.5772/intechopen.72016

Decreased ARID1A Expression Associates with Tumor Progression and Adverse Prognosis in Renal Cell CarcinomaPreprint

Somsuan, K., Samon, R., Tangjitpisud, P., Aluksanasuwan, S., Srithongc, Y., Thongboonkerd, V., & Sakulsak, N. (2021) · Research Square · doi:10.21203/rs.3.rs-1034681/v1

Traitement des tumeurs endocrines digestives par la sandostatine (octreotide sms 201. 995) : a propos de 78 cas

Blanchin, M. (1989)

Epigenetics and Chromatin Remodeling

Kinyamu, H. K., Theofilatos, D., Mackey, L. C., & Archer, T. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-95488-4.00260-6

Glucocorticoid receptor activity in triple negative breast cancer

Noureddine, L. M. (2022) · doi:10.70675/13ab50cfz7edbz4a44z918aza657b9614a4d

Biological functions of BAF57, its role in disease pathogenesis, and treatment: From molecular mechanisms to clinical translation

Li, Y., Shen, J., Zhong, L., Huang, S., Deng, Q., Tang, Y., Hu, P., & Wu, Y. (2026) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2026.06.004

Bovine α-herpesvirus 1 replication and immediate early transcription unit 1 promoter are jointly stimulated by glucocorticoid receptor and DNA-dependent ATPases

El-mayet, F. S., Clair, M. S., Costello, B., Ostler, J. B., & Jones, C. (2026) · Journal of General Virology · doi:10.1099/jgv.0.002301

Disruption of SWI/SNF ATPases in the mouse liver impairs diurnal gene expression associated with specific promoter features

Toft, N. I., Goitea, V. E., Præstholm, S. M., Correia, C. M., Heyde, I., Siersbæk, M. S., Oster, H., & Grøntved, L. (2026) · Nature Communications · doi:10.1038/s41467-026-77798-1

Reconstitution of Glucocorticoid Receptor-Dependent Transcription In Vivo

Trotter, K. W., & Archer, T. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.8.3347-3358.2004 · Cited by 107 · see citing works

Rapid Periodic Binding and Displacement of the Glucocorticoid Receptor during Chromatin Remodeling

Nagaich, A. K., Walker, D. A., Wolford, R. G., & Hager, G. L. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00178-9 · Cited by 239 · see citing works

BAF60a Mediates Critical Interactions between Nuclear Receptors and the BRG1 Chromatin-Remodeling Complex for Transactivation

Hsiao, P., Fryer, C. J., Trotter, K. W., Wang, W., & Archer, T. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.17.6210-6220.2003 · Cited by 202 · see citing works

Recruitment of the SWI-SNF Chromatin Remodeling Complex as a Mechanism of Gene Activation by the Glucocorticoid Receptor τ1 Activation Domain

Wallberg, A. E., Neely, K. E., Hassan, A. H., Gustafsson, J.-Α., Workman, J. L., & Wright, A. P. H. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.6.2004-2013.2000 · Cited by 134 · see citing works

The HSA Domain of BRG1 Mediates Critical Interactions Required for Glucocorticoid Receptor-Dependent Transcriptional Activation In Vivo

Trotter, K. W., Fan, H.-Y., Ivey, M. L., Kingston, R. E., & Archer, T. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01301-07 · Cited by 65 · see citing works