Subject's own name as a novel in a MMN design: A combined ERP and PET study
Abstract
With a view to elaborating a clinical tool to assess cognitive functions in brain-damaged patients, we had previously displayed characteristic patterns of ERPs (32 electrodes) in awake healthy persons in response to their own name (SON) presented as a novel in a passive oddball paradigm. In the present combined ERP and PET study, in an attempt to identify brain correlates of duration MMN and response to SON uttered by a familiar (FV) or an unknown voice (NFV), we used a block design protocol as close as possible to the aforementioned SON protocol. ERP data showed robust duration MMN and novelty P3 in response to SON similar to our previous results. The PET technique did not allow true MMN generators to be disclosed, but blocks with duration deviants elicited an increase of activation in the right temporal pole as compared with the control condition with no deviants, supporting the hypothesis of right hemispheric dominance in early sound discrimination. For SON contrasts, robust cerebral blood flow activation present over temporal, frontal and parietal cortices, in the hippocampus and in the precuneus could be associated with speech, novelty and self-recognition processing. Familiar and unfamiliar voices activated the prefrontal cortex differently, suggesting different retrieval processes, although corresponding ERP responses could not be differentiated.
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Hearing one's own name consistently increases activity in the medial prefrontal cortex (mPFC).
“Studies investigating the underlying neural correlates of hearing one ' s name consistently identify increased activity of the medial prefrontal cortex (mPFC”
From Exploring Theater Neuroscience: Using Wearable Functional Near-infrared Spectroscopy to Measure the Sense of Self and Interpersonal Coordination in Professional Actors (2022) · cites this paper as Holeckova et al., 2008
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- Authors
- Holeckova, I., Fischer, C., Morlet, D., Delpuech, C., Costes, N., & Mauguière, F.
- Affiliations
- Lyon 1 Université (FR)
- Centre d'Exploration et de Recherche Médicale par Emission de Positons (FR)
- Corresponding author
- Fischer, Catherine
- Venue
- Brain Research
- Publisher
- Elsevier BV
- Published
- 2008-01
- Volume
- 1189
- Pages
- 152-165
- ISSN
- 0006-8993 (ISSN-L)
- OpenAlex
- W2001350720
- Cited by
- 76
- References
- 86
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 6 · 2021: 2 · 2020: 3 · 2019: 17 · 2018: 3 · 2017: 1 · 2016: 5 · 2015: 4 · 2014: 6 · 2013: 4 · 2012: 9
- FWCI
- 0.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Keywords
- own name, P3, voice recognition, hemispheric dominance, sound discrimination, self-recognition, speech processing, hippocampus, precuneus, prefrontal cortex, cerebral blood flow
- MeSH terms
- Acoustic Stimulation, Adult, Attention, Brain Mapping, Cerebral Cortex, Cerebrovascular Circulation, Electroencephalography, Evoked Potentials, Exploratory Behavior, Humans, Language Tests, Functional Laterality, Male, Middle Aged, Nerve Net, Neuropsychological Tests, Speech Perception, Recognition, Psychology, Positron-Emission Tomography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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