The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Coupling of neurogenesis and angiogenesis after ischemic stroke
Open accessAbstract
Stroke is a leading cause of mortality and severe long-term disability worldwide. Development of effective treatment or new therapeutic strategies for ischemic stroke patients is therefore crucial. Ischemic stroke promotes neurogenesis by several growth factors including FGF-2, IGF-1, BDNF, VEGF and chemokines including SDF-1, MCP-1. Stroke-induced angiogenesis is similarly regulated by many factors most notably, eNOS and CSE, VEGF/VEGFR2, and Ang-1/Tie2. Important findings in the last decade have revealed that neurogenesis is not the stand-alone consideration in the fight for full functional recovery from stroke. Angiogenesis has been also shown to be critical in improving post-stroke neurological functional recovery. More than that, recent evidence has shown a highly possible interplay or dependence between stroke-induced neurogenesis and angiogenesis. Moving forward, elucidating the underlying mechanisms of this coupling between stroke-induced neurogenesis and angiogenesis will be of great importance, which will provide the basis for neurorestorative therapy.
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Cites
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Götz, M., & Huttner, W. B. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1739 · Cited by 2,130
Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
Jin, K., Zhu, Y., Sun, Y., Mao, X. O., Xie, L., & Greenberg, D. A. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182296499 · Cited by 1,507
Self-citationVEGF enhances angiogenesis and promotes blood–brain barrier leakage in the ischemic brain
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Self-citationVEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
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Cited by
Angiogenesis and neuronal remodeling after ischemic stroke
Kanazawa, M., Hatakeyama, M., & Ninomiya, I. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.264442 · Cited by 328
Ruan, H., Li, Y., Wang, C., Jiang, Y., Han, Y., Li, Y., Zheng, D., Ye, J., Chen, G., Yang, G.-Y., et al. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.06.007 · Cited by 95
Rho/ROCK Pathway and Noncoding RNAs: Implications in Ischemic Stroke and Spinal Cord Injury
Kimura, T., Horikoshi, Y., Kuriyagawa, C., & Niiyama, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111573 · Cited by 55
MiRNA: Involvement of the MAPK Pathway in Ischemic Stroke. A Promising Therapeutic Target
Gugliandolo, A., Silvestro, S., Sindona, C., Bramanti, P., & Mazzon, E. (2021) · Medicina · doi:10.3390/medicina57101053 · Cited by 49
Zhang, Y., Zhao, X., Guo, C., Zhang, Y., Zeng, F., Yin, Q., Li, Z., Shao, L., Zhou, D., & Liu, L. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-023-01042-9 · Cited by 25
Metadata
- Authors
- Ruan, L., Wang, B., ZhuGe, Q., & Jin, K.
- Venue
- Brain Research
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 1623
- Pages
- 166-173
- ISSN
- 0006-8993 (ISSN-L)
- OpenAlex
- W2027261562
- Cited by
- 301
- References
- 76
- FWCI
- 7.04
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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